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Black Cohosh Does Not Exert an Estrogenic Effect on the Breast

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Pages 269-277 | Received 12 Feb 2007, Accepted 22 May 2007, Published online: 05 Dec 2007

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Camil Castelo-Branco, Concepción Navarro, Estanislao Beltrán, Fernando Losa & Marta Camacho. (2022) Black cohosh efficacy and safety for menopausal symptoms. The Spanish Menopause Society statement. Gynecological Endocrinology 38:5, pages 379-384.
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Rachel Ruhlen & Edward Sauter. (2010) Plant based therapies to prevent/treat cancer. Expert Review of Clinical Pharmacology 3:1, pages 1-3.
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Articles from other publishers (26)

Sradhanjali Mohapatra, P Ayash Kumar, Akshay Aggarwal, Ashif Iqubal, Mohd Aamir Mirza & Zeenat Iqbal. (2024) Phytotherapeutic approach for conquering menopausal syndrome and osteoporosis. Phytotherapy Research.
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Yuan Le, Xilin Li, Si Chen, Kylie G. Ning, Xiaoqing Guo, Charles G. Wu, Mugimane G. Manjanatha & Nan Mei. (2022) Actein contributes to black cohosh extract‐induced genotoxicity in human TK6 cells. Journal of Applied Toxicology 42:9, pages 1491-1502.
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Maša Sinreih, Klara Gregorič, Kristina Gajser & Tea Lanišnik Rižner. (2022) Physiological Concentrations of Cimicifuga racemosa Extract Do Not Affect Expression of Genes Involved in Estrogen Biosynthesis and Action in Endometrial and Ovarian Cell Lines. Biomolecules 12:4, pages 545.
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Sradhanjali Mohapatra, Ashif Iqubal, Mohammad Javed Ansari, Bisma Jan, Sultan Zahiruddin, Mohd Aamir Mirza, Sayeed Ahmad & Zeenat Iqbal. (2022) Benefits of Black Cohosh (Cimicifuga racemosa) for Women Health: An Up-Close and In-Depth Review. Pharmaceuticals 15:3, pages 278.
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Ji-Eun Seo, Xiaoqing Guo, Dayton M Petibone, Sharon D Shelton, Ying Chen, Xilin Li, Volodymyr Tryndyak, Stephanie L Smith-Roe, Kristine L Witt, Nan Mei & Mugimane G Manjanatha. (2021) Mechanistic Evaluation of Black Cohosh Extract-Induced Genotoxicity in Human Cells. Toxicological Sciences 182:1, pages 96-106.
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Lucille R. Marchand & James A. Stewart. 2018. Integrative Medicine. Integrative Medicine 772 784.e7 .
Birgit M. Dietz, Atieh Hajirahimkhan, Tareisha L. Dunlap & Judy L. Bolton. (2016) Botanicals and Their Bioactive Phytochemicals for Women’s Health. Pharmacological Reviews 68:4, pages 1026-1073.
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Wolfgang Wuttke & Dana Seidlová-Wuttke. (2015) Black cohosh (Cimicifuga racemosa) is a non-estrogenic alternative to hormone replacement therapy. Clinical Phytoscience 1:1.
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Juergen Drewe, Kathleen A Bucher & Catherine Zahner. (2015) A systematic review of non-hormonal treatments of vasomotor symptoms in climacteric and cancer patients. SpringerPlus 4:1.
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Marwa R. Amer, Gabriela C. Cipriano, Jineane V. Venci & Mona A. Gandhi. (2015) Safety of Popular Herbal Supplements in Lactating Women. Journal of Human Lactation 31:3, pages 348-353.
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Dejan Nikolić, David C. Lankin, Tamara Cisowska, Shao-Nong Chen, Guido F. Pauli & Richard B. van Breemen. 2015. The Formation, Structure and Activity of Phytochemicals. The Formation, Structure and Activity of Phytochemicals 31 75 .
Dejan Nikolić, Jinghu Li & Richard B. van Breemen. (2014) Metabolism of N ω ‐methylserotonin, a serotonergic constituent of black cohosh ( Cimicifuga racemosa , L. (Nutt.)), by human liver microsomes . Biomedical Chromatography 28:12, pages 1647-1651.
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Heidi Fritz, Dugald Seely, Jessie McGowan, Becky Skidmore, Rochelle Fernandes, Deborah A. Kennedy, Kieran Cooley, Raimond Wong, Stephen Sagar, Lynda G. Balneaves & Dean Fergusson. (2013) Black Cohosh and Breast Cancer. Integrative Cancer Therapies 13:1, pages 12-29.
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Wolfgang Wuttke, Hubertus Jarry, Jutta Haunschild, Guenter Stecher, Markus Schuh & Dana Seidlova-Wuttke. (2014) The non-estrogenic alternative for the treatment of climacteric complaints: Black cohosh (Cimicifuga or Actaea racemosa). The Journal of Steroid Biochemistry and Molecular Biology 139, pages 302-310.
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A.-M. Beer & A. Neff. (2013) Differentiated Evaluation of Extract-Specific Evidence on Cimicifuga racemosa 's Efficacy and Safety for Climacteric Complaints . Evidence-Based Complementary and Alternative Medicine 2013, pages 1-21.
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. 2013. Principles and Practice of Phytotherapy. Principles and Practice of Phytotherapy 353 961 .
Wolfgang Wuttke & Dana Seidlova-Wuttke. 2013. Evidence and Rational Based Research on Chinese Drugs. Evidence and Rational Based Research on Chinese Drugs 397 430 .
Lucille R. Marchand. 2012. Integrative Medicine. Integrative Medicine 692 703.e4 .
Kapil K. Soni, Temitope O. Lawal, Tracie D. Locklear & Gail B. Mahady. (2011) Black Cohosh for Menopause: Safety and Efficacy Issues and Future Perspectives. Drug Information Journal 45:1, pages 37-44.
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. 2011. A Guide to Evidence-based Integrative and Complementary Medicine. A Guide to Evidence-based Integrative and Complementary Medicine 590 608 .
M. Dolores Juliá, Javier Ferrer, Francisco Quereda, Concepción Navarro, Carmen Menéndez, Nicolás Mendoza, Andrés Forteza, Camil Castelo-Branco, M. Jesús Cornellana, M. Jesús Cancelo, Estanislao Beltrán, Luis Ignacio Bachiller, Josep Allué, José Villero, Rafael Sánchez-Borrego, Santiago Palacios, Javier Haya & Magdalena Durán. (2009) Posicionamiento de la Asociación Española para el Estudio de la Menopausia sobre el uso clínico de la Cimicífuga racemosa en el climaterio. Progresos de Obstetricia y Ginecología 52:12, pages 712-721.
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Kimberly Braxton Lloyd & Lori B. Hornsby. (2009) Complementary and Alternative Medications for Women's Health Issues. Nutrition in Clinical Practice 24:5, pages 589-608.
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Sharon J. Wayne, Marian L. Neuhouser, Carol Koprowski, Cornelia M. Ulrich, Charles Wiggins, Frank Gilliland, Kathy B. Baumgartner, Richard N. Baumgartner, Anne McTiernan, Leslie Bernstein & Rachel Ballard-Barbash. (2008) Breast cancer survivors who use estrogenic botanical supplements have lower serum estrogen levels than non users. Breast Cancer Research and Treatment 117:1, pages 111-119.
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Joseph M. Betz, Linda Anderson, Mark I. Avigan, Joanne Barnes, Norman R. Farnsworth, Barbro Gerdén, Leigh Henderson, Edward J. Kennelly, Uwe Koetter, Stephanie Lessard, Tieraona Low Dog, Michelle McLaughlin, Belal Naser, Ruediger G. W. Osmers, Linda S. Pellicore, John R. Senior, Richard B. van Breemen, Wolfgang Wuttke & John H. Cardellina. (2009) Black Cohosh. Nutrition Today 44:4, pages 155-162.
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Carlos Palacio, Ghania Masri & Arshag D Mooradian. (2009) Black Cohosh for the Management of Menopausal Symptoms. Drugs & Aging 26:1, pages 23-36.
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Vicki L. Davis, Manuel J. Jayo, Arline Ho, Mary P. Kotlarczyk, Mary L. Hardy, Warren G. Foster & Claude L. Hughes. (2008) Black Cohosh Increases Metastatic Mammary Cancer in Transgenic Mice Expressing c- erb B2 . Cancer Research 68:20, pages 8377-8383.
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