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Nutrition and Cancer Volume 60, 2007 - Issue 1
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Original Articles

Deoxycholic Acid Can Induce Apoptosis in the Human Colon Cancer Cell Line HCT116 in the Absence of Bax

Satoko Yui Laboratory of Molecular Nutrition, Graduate School of Agriculture, Kyoto Prefectural University, Kyoto, Japan
,
Ryuhei Kanamoto Laboratory of Molecular Nutrition, Graduate School of Agriculture, Kyoto Prefectural University, Kyoto, Japan
&
Tohru Saeki Laboratory of Molecular Nutrition, Graduate School of Agriculture, Kyoto Prefectural University, Kyoto, Japan
Pages 91-96 | Received 10 Nov 2006, Accepted 12 Jun 2007, Published online: 02 Jan 2008

Citations (16)

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Satoko Yui, Ryuhei Kanamoto & Tohru Saeki. (2009) Biphasic Regulation of Cell Death and Survival by Hydrophobic Bile Acids in HCT116 Cells. Nutrition and Cancer 61:3, pages 374-380.
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Vassiliki Costarelli. (2009) Bile acids as possible human carcinogens: new tricks from an old dog. International Journal of Food Sciences and Nutrition 60:sup6, pages 116-125.
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Articles from other publishers (14)

Kulvinder Kochar Kaur, Gautam Nand K. Allahbadia & Mandeep Singh. (2022) Mode of Actions of Bile Acids in Avoidance of Colorectal Cancer Development; and their Therapeutic Applications in Cancers - A Narrative Review. Journal of Pharmacy and Nutrition Sciences 12, pages 35-53.
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Ziyue Wang, Hui Liu, Lu Li, Yucai Li, Haiyang Yan & Yuan Yuan. (2022) Modulation of Disordered Bile Acid Homeostasis and Hepatic Tight Junctions Using Salidroside against Hepatocyte Apoptosis in Furan-Induced Mice. Journal of Agricultural and Food Chemistry 70:32, pages 10031-10043.
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Jung Yoon Jang, Eunok Im, Yung Hyun Choi & Nam Deuk Kim. (2022) Mechanism of Bile Acid-Induced Programmed Cell Death and Drug Discovery against Cancer: A Review. International Journal of Molecular Sciences 23:13, pages 7184.
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Yamila B. Gándola, Camila Fontana, Mariana A. Bojorge, Tania T. Luschnat, Marcela A. Moretton, Diego A. Chiapetta, Sandra V. Verstraeten & Lorena González. (2020) Concentration-dependent effects of sodium cholate and deoxycholate bile salts on breast cancer cells proliferation and survival. Molecular Biology Reports 47:5, pages 3521-3539.
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Senthilkumar Rajagopal & Murugavel PonnusamySenthilkumar Rajagopal & Murugavel Ponnusamy. 2018. Metabotropic GPCRs: TGR5 and P2Y Receptors in Health and Diseases. Metabotropic GPCRs: TGR5 and P2Y Receptors in Health and Diseases 57 76 .
HAI-BO YANG, WEI SONG, MEI-DIE CHENG, HAI-FANG FAN, XU GU, YING QIAO, XIN LU, RUI-HE YU & LAN-YING CHEN. (2015) Deoxycholic acid inhibits the growth of BGC-823 gastric carcinoma cells via a p53-mediated pathway. Molecular Medicine Reports 11:4, pages 2749-2754.
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Hana Ajouz, Deborah Mukherji & Ali Shamseddine. (2014) Secondary bile acids: an underrecognized cause of colon cancer. World Journal of Surgical Oncology 12:1.
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Juan I. Barrasa, Nieves Olmo, Ma Antonia Lizarbe & Javier Turnay. (2013) Bile acids in the colon, from healthy to cytotoxic molecules. Toxicology in Vitro 27:2, pages 964-977.
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Marine Baptissart, Aurelie Vega, Salwan Maqdasy, Françoise Caira, Silvère Baron, Jean-Marc A. Lobaccaro & David H. Volle. (2013) Bile acids: From digestion to cancers. Biochimie 95:3, pages 504-517.
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Chiara Degirolamo, Salvatore Modica, Giuseppe Palasciano & Antonio Moschetta. (2011) Bile acids and colon cancer: Solving the puzzle with nuclear receptors. Trends in Molecular Medicine 17:10, pages 564-572.
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Riccardo Solimando, Franco Bazzoli & Luigi Ricciardiello. (2011) Chemoprevention of colorectal cancer: A role for ursodeoxycholic acid, folate and hormone replacement treatment?. Best Practice & Research Clinical Gastroenterology 25:4-5, pages 555-568.
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Harris Bernstein, Carol Bernstein, Claire M Payne & Katerina Dvorak. (2009) Bile acids as endogenous etiologic agents in gastrointestinal cancer. World Journal of Gastroenterology 15:27, pages 3329.
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Kannan Krishnamurthy, Guanghu Wang, Dmitriy Rokhfeld & Erhard Bieberich. (2008) Deoxycholate promotes survival of breast cancer cells by reducing the level of pro-apoptotic ceramide. Breast Cancer Research 10:6.
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Jennifer M. Longpre & George Loo. (2008) Protection of human colon epithelial cells against deoxycholate by rottlerin. Apoptosis 13:9, pages 1162-1171.
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