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Nutrition and Cancer Volume 60, 2008 - Issue 3
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Original Article

Phase 1 Study of Topical Perillyl Alcohol Cream for Chemoprevention of Skin Cancer

Steven P. Stratton Arizona Cancer Center and Department of Medicine, College of Medicine, University of Arizona, Tucson, Arizona, USA
,
Kathy Lynn Saboda Arizona Cancer Center, University of Arizona, Tucson, Arizona, USA
,
Paul B. Myrdal Arizona Cancer Center and Department of Pharmacy Practice & Science, College of Pharmacy, University of Arizona, Tucson, Arizona, USA
,
Abhishek Gupta Nektar Therapeutics, San Carlos, California, USA
,
Naja E. McKenzie Arizona Cancer Center, University of Arizona, Tucson, Arizona, USA
,
Chris Brooks Arizona Cancer Center, University of Arizona, Tucson, Arizona, USA
,
Stuart J. Salasche Arizona Cancer Center and Department of Medicine, College of Medicine, University of Arizona, Tucson, Arizona, USA
,
James A. Warneke Arizona Cancer Center and Department of Surgery, College of Medicine, University of Arizona, Tucson, Arizona, USA
,
James Ranger-Moore Arizona Cancer Center and Division of Epidemiology & Biostatistics, College of Public Health, University of Arizona, Tucson, Arizona, USA
,
Paul D. Bozzo Arizona Cancer Center, University of Arizona, Tucson, Arizona, USA
,
James Blanchard Department of Pharmacy Practice & Science, College of Pharmacy, University of Arizona, Tucson, Arizona, USA
,
Janine G. Einspahr Arizona Cancer Center and Department of Medicine, College of Medicine, University of Arizona, Tucson, Arizona, USA
,
Robert T. Dorr Arizona Cancer Center and Department of Pharmacology, College of Medicine, University of Arizona, Tucson, Arizona, USA
,
Norman Levine Department of Medicine, College of Medicine, University of Arizona, Tucson, Arizona, USA
&
David S. Alberts Arizona Cancer Center, University of Arizona, Tucson, Arizona, USA; Department of Medicine, College of Medicine, University of Arizona, Tucson, Arizona, USA; Division of Epidemiology & Biostatistics, College of Public Health, University of Arizona, Tucson, Arizona, USA; Department of Pharmacology, College of Medicine, University of Arizona, Tucson, Arizona, USA
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Pages 325-330 | Received 23 Apr 2007, Accepted 26 Aug 2007, Published online: 28 Apr 2008

Citations (14)

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Read on this site (2)

Brian Berman & Sadegh Amini. (2012) Pharmacotherapy of actinic keratosis: an update. Expert Opinion on Pharmacotherapy 13:13, pages 1847-1871.
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Brian Berman, Sadegh Amini, Whitney Valins & Samantha Block. (2009) Pharmacotherapy of actinic keratosis. Expert Opinion on Pharmacotherapy 10:18, pages 3015-3031.
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Articles from other publishers (12)

Thomas C. Chen, Clovis O. da Fonseca, Daniel Levin & Axel H. Schönthal. (2021) The Monoterpenoid Perillyl Alcohol: Anticancer Agent and Medium to Overcome Biological Barriers. Pharmaceutics 13:12, pages 2167.
Crossref
Marta Di Martile, Stefania Garzoli, Rino Ragno & Donatella Del Bufalo. (2020) Essential Oils and Their Main Chemical Components: The Past 20 Years of Preclinical Studies in Melanoma. Cancers 12:9, pages 2650.
Crossref
P.S. Pavithra, Alka Mehta & Rama S. Verma. (2019) Essential oils: from prevention to treatment of skin cancer. Drug Discovery Today 24:2, pages 644-655.
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J.F. Tomaz-Morais, R.M. Braga, F.B. de Sousa, D.P. de Sousa, L.C. deM. Pordeus, R.N. de Almeida & R.D. de Castro. (2017) Orofacial antinociceptive activity of (S)-(−)-perillyl alcohol in mice: a randomized, controlled and triple-blind study. International Journal of Oral and Maxillofacial Surgery 46:5, pages 662-667.
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Jessica Mounessa, Rosie Qin, Cory A. Dunnick & Robert P. Dellavalle. (2016) Chemoprevention of Keratinocyte Carcinomas: An Updated Review. American Journal of Clinical Dermatology 17:5, pages 475-484.
Crossref
M.C.F. Simões, J.J.S. Sousa & A.A.C.C. Pais. (2015) Skin cancer and new treatment perspectives: A review. Cancer Letters 357:1, pages 8-42.
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. 2014. Essential Oil Safety. Essential Oil Safety 677 755 .
Shahla Shojaei, Amir Kiumarsi, Adel Rezaei Moghadam, Javad Alizadeh, Hassan Marzban & Saeid Ghavami. 2014. Natural Products and Cancer Signaling: Isoprenoids, Polyphenols and Flavonoids. Natural Products and Cancer Signaling: Isoprenoids, Polyphenols and Flavonoids 7 32 .
Renata Prado, Shayla O. Francis, Mariah N. Mason, Gregory Wing, Ryan G. Gamble & Robert Dellavalle. (2011) Nonmelanoma Skin Cancer Chemoprevention. Dermatologic Surgery 37:11, pages 1566-1578.
Crossref
Victoria Williams, Theodore Rosen, Roger I. Ceilley, James Q. del Rosso & Eggert Stockfleth. 2011. Cancer of the Skin. Cancer of the Skin 462 476 .
G. Tim Bowden & David S. Alberts. 2011. Signaling Pathways in Squamous Cancer. Signaling Pathways in Squamous Cancer 335 363 .
Steven P. Stratton, David S. Alberts, Janine G. Einspahr, Paul M. Sagerman, James A. Warneke, Clara Curiel-Lewandrowski, Paul B. Myrdal, Kelly L. Karlage, Brian J. Nickoloff, Chris Brooks, Kathylynn Saboda, Michael L. Yozwiak, Mary F. Krutzsch, Chengcheng Hu, Maria Lluria-Prevatt, Zigang Dong, G. Timothy Bowden & Peter H. Bartels. (2010) A Phase 2a Study of Topical Perillyl Alcohol Cream for Chemoprevention of Skin Cancer. Cancer Prevention Research 3:2, pages 160-169.
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