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Nutrition and Cancer Volume 64, 2012 - Issue 4
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Original Articles

Inhibitory Effect of Liquiritigenin on Migration Via Downregulation ProMMP-2 and PI3K/Akt Signaling Pathway in Human Lung Adenocarcinoma A549 cells

Yu Wang Department of Nutrition and Food Hygiene, School of Public Health, Nanjing Medical University, Nanjing, China
,
Sirou Xie Department of Nutrition and Food Hygiene, School of Public Health, Nanjing Medical University, Nanjing, China
,
Changwei Liu Department of Nutrition and Food Hygiene, School of Public Health, Nanjing Medical University, Nanjing, China
,
Yuchen Wu Department of Nutrition and Food Hygiene, School of Public Health, Nanjing Medical University, Nanjing, China
,
Yuxin Liu Department of Nutrition and Food Hygiene, School of Public Health, Nanjing Medical University, Nanjing, China
&
Yunqing Cai Department of Nutrition and Food Hygiene, School of Public Health, Nanjing Medical University, Nanjing, China
Pages 627-634 | Received 24 May 2011, Accepted 11 Mar 2012, Published online: 20 Apr 2012

Citations (23)

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Hui Shi, Yuchen Wu, Yang Wang, Ming Zhou, Shu Yan, Zhimin Chen, Dawei Gu & Yunqing Cai. (2015) Liquiritigenin Potentiates the Inhibitory Effects of Cisplatin on Invasion and Metastasis Via Downregulation MMP-2/9 and PI3 K/AKT Signaling Pathway in B16F10 Melanoma Cells and Mice Model. Nutrition and Cancer 67:5, pages 761-770.
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Articles from other publishers (22)

Lei Bao, Pei Hao, Meiju Jiang & Weijiang Chu. (2023) Liquiritigenin regulates insulin sensitivity and ameliorates inflammatory responses in the nonalcoholic fatty liver by activation PI3K / AKT pathway . Chemical Biology & Drug Design.
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Leihao Hu, Canfeng He, Aier Mo, Xingkai Zhan, Caizhi Yang, Wei Guo, Lingling Sun, Weiwei Su & Lizhu Lin. (2023) A Mechanism Exploration for the Yi-Fei-San-Jie Formula against Non-Small-Cell Lung Cancer Based on UPLC-MS/MS, Network Pharmacology, and In Silico Verification. Evidence-Based Complementary and Alternative Medicine 2023, pages 1-16.
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Rui-fei Xie, Zi-yu Song, Lu-yao Xu-shao, Jin-ge Huang, Ting Zhao & Zi Yang. (2022) The mechanism of Bai He Gu Jin Tang against non-small cell lung cancer revealed by network pharmacology and molecular docking. Medicine 101:52, pages e32555.
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Weiwei Wang, Weiliang Gu, Chao He, Tong Zhang, Yao Shen & Yiqiong Pu. (2022) Bioactive components of Banxia Xiexin Decoction for the treatment of gastrointestinal diseases based on flavor-oriented analysis. Journal of Ethnopharmacology 291, pages 115085.
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Yu Li, Pachaiyappan Saravana Kumar, Jiao qiu, Yalan Ran, Xuhui Tan, Renjun Zhao, Lunqiang Ai, Mingyuan Yuan, Ji Zhu & Meijun He. (2022) Production of bioactive compounds from callus of Pueraria thomsonii Benth with promising cytotoxic and antibacterial activities. Arabian Journal of Chemistry 15:6, pages 103854.
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Zhixin Zhang, Lin Yang, Jiaming Hou, Shaokai Tian & Ying Liu. (2021) Molecular mechanisms underlying the anticancer activities of licorice flavonoids. Journal of Ethnopharmacology 267, pages 113635.
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Hyun-Su Lee, Eun-Nam Kim & Gil-Saeng Jeong. (2020) Oral Administration of Liquiritigenin Confers Protection from Atopic Dermatitis through the Inhibition of T Cell Activation. Biomolecules 10:5, pages 786.
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Po-Han Lin, Hsiang-Lin Kung, Hsin-Yuan Chen, Ko-Chieh Huang & Shih-Min Hsia. (2019) Isoliquiritigenin Suppresses E2-Induced Uterine Leiomyoma Growth through the Modulation of Cell Death Program and the Repression of ECM Accumulation. Cancers 11:8, pages 1131.
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Gonçalo P. Rosa, Ana M. L. Seca, Maria do Carmo Barreto, Artur M. S. Silva & Diana C. G. A. Pinto. (2019) Chalcones and Flavanones Bearing Hydroxyl and/or Methoxyl Groups: Synthesis and Biological Assessments. Applied Sciences 9:14, pages 2846.
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Fan-Chun Meng & Jun-Kai Lin. (2019) Liquiritigenin Inhibits Colorectal Cancer Proliferation, Invasion, and Epithelial-to-Mesenchymal Transition by Decreasing Expression of Runt-Related Transcription Factor 2. Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics 27:2, pages 139-146.
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Judyta Kruk, Irena Baranowska, Bogusław Buszewski, Sylwia Bajkacz, Bartosz Kowalski & Magdalena Ligor. (2019) Flavonoids enantiomer distribution in different parts of goldenrod ( Solidago virgaurea L.), lucerne ( Medicago sativa L.) and phacelia ( Phacelia tanacetifolia Benth.) . Chirality 31:2, pages 138-149.
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Nancy Jaiswal, Yashodhara Verma & Pragati Misra. (2017) Micropropagation and in vitro elicitation of licorice (Glycyrrhiza spp.). In Vitro Cellular & Developmental Biology - Plant 53:3, pages 145-166.
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Yanfang Yang, Guijun Zhang, Qiyu Sun, Liang Liu, Hui Peng, Jingjuan Wang & Li Xiang. (2017) Simultaneous Determination of 8 Compounds in Gancao-Ganjiang-Tang by HPLC-DAD and Analysis of the Relations between Compatibility, Dosage, and Contents of Medicines. Evidence-Based Complementary and Alternative Medicine 2017, pages 1-8.
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Irena Baranowska, Judyta Hejniak & Sylwia Magiera. (2017) LC-ESI-MS/MS method for the enantioseparation of six flavanones. Analytical Methods 9:6, pages 1018-1030.
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Nilanjan Adhikari, Amit K. Halder, Sumana Mallick, Achintya Saha, Kishna D. Saha & Tarun Jha. (2016) Robust design of some selective matrix metalloproteinase-2 inhibitors over matrix metalloproteinase-9 through in silico/fragment-based lead identification and de novo lead modification: Syntheses and biological assays. Bioorganic & Medicinal Chemistry 24:18, pages 4291-4309.
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Gangadhara R Sareddy & Ratna K. Vadlamudi. (2015) Cancer therapy using natural ligands that target estrogen receptor beta. Chinese Journal of Natural Medicines 13:11, pages 801-807.
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Guang Li, Kai Yu, Fushuang Li, Kangping Xu, Jing Li, Shujin He, Shousong Cao & Guishan Tan. (2014) Anticancer potential of Hericium erinaceus extracts against human gastrointestinal cancers. Journal of Ethnopharmacology 153:2, pages 521-530.
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Di Wang, Hei-Kiu Wong, Yi-Bin Feng & Zhang-Jin Zhang. (2014) Liquiritigenin exhibits antitumour action in pituitary adenoma cells via Ras/ERKs and ROS-dependent mitochondrial signalling pathways. Journal of Pharmacy and Pharmacology 66:3, pages 408-417.
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Xiaoying Wang, Han Zhang, Lili Chen, Lihua Shan, Guanwei Fan & Xiumei Gao. (2013) Liquorice, a unique “guide drug” of traditional Chinese medicine: A review of its role in drug interactions. Journal of Ethnopharmacology 150:3, pages 781-790.
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Charlotte Simmler, Atieh Hajirahimkhan, David C. Lankin, Judy L. Bolton, Tristesse Jones, Djaja D. Soejarto, Shao-Nong Chen & Guido F. Pauli. (2013) Dynamic Residual Complexity of the Isoliquiritigenin–Liquiritigenin Interconversion During Bioassay. Journal of Agricultural and Food Chemistry 61:9, pages 2146-2157.
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Zhaoguo Xu & Rong Wu. (2012) Alteration in Metastasis Potential and Gene Expression in Human Lung Cancer Cell Lines by ITGB8 Silencing. The Anatomical Record 295:9, pages 1446-1454.
Crossref
Yuxin Liu, Sirou Xie, Yu Wang, Kang Luo, Yang Wang & Yunqing Cai. (2012) Liquiritigenin Inhibits Tumor Growth and Vascularization in a Mouse Model of Hela Cells. Molecules 17:6, pages 7206-7216.
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