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Nutrition and Cancer Volume 64, 2012 - Issue 6
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Original Articles

Reduction in Colon Cancer Risk by Consumption of Kava or Kava Fractions in Carcinogen-Treated Rats

Julie Triolet Department of Food Science and Nutrition, University of Minnesota, St. Paul, Minnesota, USA
,
Ahmad Ali Shaik Department of Medicinal Chemistry, University of Minnesota, Minneapolis, Minnesota, USA
,
Daniel D. Gallaher Department of Food Science and Nutrition, University of Minnesota, St. Paul, Minnesota, USA
,
Michael G. O’Sullivan Department of Veterinary Population Medicine, University of Minnesota, St. Paul, Minneapolis, USA
&
Chengguo Xing Department of Medicinal Chemistry, University of Minnesota, Minneapolis, Minnesota, USA
Pages 838-846 | Received 21 Nov 2011, Accepted 16 Apr 2012, Published online: 13 Jun 2012

Citations (15)

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Ajmila Islam & Daniel D. Gallaher. (2015) Wheat Type (Class) Influences Development and Regression of Colon Cancer Risk Markers in Rats. Nutrition and Cancer 67:8, pages 1285-1294.
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Articles from other publishers (14)

Breanne Freeman, Jessica Mamallapalli, Tengfei Bian, Kayleigh Ballas, Allison Lynch, Alexander Scala, Zhiguang Huo, Kristianna M. Fredenburg, Adriaan W. Bruijnzeel, Carolyn J. Baglole, Junxuan Lu, Ramzi G. Salloum, John Malaty & Chengguo Xing. (2023) Opportunities and Challenges of Kava in Lung Cancer Prevention. International Journal of Molecular Sciences 24:11, pages 9539.
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Jessica Mamallapalli, Siva Rama Raju Kanumuri, Pedro Corral, Edward Johnston, Chunlin Zhuang, Christopher R. McCurdy, Carol A. Mathews, Abhisheak Sharma & Chengguo Xing. (2021) Characterization of Different Forms of Kava (Piper methysticum) Products by UPLC-MS/MS. Planta Medica 88:14, pages 1348-1359.
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Siva Rama Raju Kanumuri, Jessica Mamallapalli, Robyn Nelson, Christopher R. McCurdy, Carol A. Mathews, Chengguo Xing & Abhisheak Sharma. (2022) Clinical pharmacokinetics of kavalactones after oral dosing of standardized kava extract in healthy volunteers. Journal of Ethnopharmacology 297, pages 115514.
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Rita B. Soares, Ricardo Jorge Dinis-Oliveira & Nuno G. Oliveira. (2022) An Updated Review on the Psychoactive, Toxic and Anticancer Properties of Kava. Journal of Clinical Medicine 11:14, pages 4039.
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C. Jansen, J.D. Baker, E. Kodaira, L. Ang, A.J. Bacani, J.T. Aldan, L.M.N. Shimoda, M. Salameh, A.L. Small-Howard, A.J. Stokes, H. Turner & C.N. Adra. (2021) Medicine in motion: Opportunities, challenges and data analytics-based solutions for traditional medicine integration into western medical practice. Journal of Ethnopharmacology 267, pages 113477.
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Tengfei Bian, Pedro Corral, Yuzhi Wang, Jordy Botello, Rick Kingston, Tyler Daniels, Ramzi G. Salloum, Edward Johnston, Zhiguang Huo, Junxuan Lu, Andrew C. Liu & Chengguo Xing. (2020) Kava as a Clinical Nutrient: Promises and Challenges. Nutrients 12:10, pages 3044.
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Yi Wang, Sreekanth C. Narayanapillai, Katelyn M. Tessier, Lori G. Strayer, Pramod Upadhyaya, Qi Hu, Rick Kingston, Ramzi G. Salloum, Junxuan Lu, Stephen S. Hecht, Dorothy K. Hatsukami, Naomi Fujioka & Chengguo Xing. (2020) The Impact of One-week Dietary Supplementation with Kava on Biomarkers of Tobacco Use and Nitrosamine-based Carcinogenesis Risk among Active Smokers. Cancer Prevention Research 13:5, pages 483-492.
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You‐Cheng Hseu, Ting‐Yu Yang, Mei‐Ling Li, Peramaiyan Rajendran, Dony Chacko Mathew, Chia‐Hsuan Tsai, Ruei‐Wan Lin, Chuan‐Chen Lee & Hsin‐Ling Yang. (2018) Chalcone flavokawain A attenuates TGF ‐β1‐induced fibrotic pathology via inhibition of ROS /Smad3 signaling pathways and induction of Nrf2/ ARE ‐mediated antioxidant genes in vascular smooth muscle cells . Journal of Cellular and Molecular Medicine 23:2, pages 775-788.
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L.S. Einbond, A. Negrin, D.M. Kulakowski, H.-A. Wu, V. Antonetti, F. Jalees, W. Law, M. Roller, S. Redenti, E.J. Kennelly & M.J. Balick. (2017) Traditional preparations of kava (Piper methysticum) inhibit the growth of human colon cancer cells in vitro. Phytomedicine 24, pages 1-13.
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Su-Ni Tang, Jinhui Zhang, Peixin Jiang, Palika Datta, Pablo Leitzman, M. Gerard O'Sullivan, Cheng Jiang, Chengguo Xing & Junxuan Lü. (2016) Gene expression signatures associated with suppression of TRAMP prostate carcinogenesis by a kavalactone-rich Kava fraction. Molecular Carcinogenesis 55:12, pages 2291-2303.
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T. K. LimT. K. Lim. 2016. Edible Medicinal and Non-Medicinal Plants. Edible Medicinal and Non-Medicinal Plants 147 196 .
Dong Fu & Iqbal Ramzan. 2015. Phytotherapies. Phytotherapies 312 329 .
Sreekanth C. Narayanapillai, Pablo Leitzman, M. Gerard O’Sullivan & Chengguo Xing. (2014) Flavokawains A and B in Kava, Not Dihydromethysticin, Potentiate Acetaminophen-Induced Hepatotoxicity in C57BL/6 Mice. Chemical Research in Toxicology 27:10, pages 1871-1876.
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Xuesen Li, Xia Xu, Tao Ji, Zhongbo Liu, Mai Gu, Bang H. Hoang & Xiaolin Zi. (2014) Dietary feeding of flavokawain A, a Kava chalcone, exhibits a satisfactory safety profile and its association with enhancement of phase II enzymes in mice. Toxicology Reports 1, pages 2-11.
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