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Nutrition and Cancer Volume 65, 2013 - Issue 7
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Original Articles

Influence of Lycopene on Cell Viability, Cell Cycle, and Apoptosis of Human Prostate Cancer and Benign Hyperplastic Cells

Nathalia da Costa Pereira Soares Programa de Pesquisa em Ciência de Alimentos, Instituto de Química, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil
,
Anderson Junger Teodoro Laboratório de Bioquímica Nutricional, Programa de Alimentos e Nutrição, Universidade Federal do Estado do Rio de Janeiro, Rio de Janeiro, Brazil
,
Felipe Leite Oliveira Laboratório de Proliferação e Diferenciação Celular, Instituto de Ciências Biomédicas, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil
,
Carlos Antonio do Nascimento Santos Instituto Nacional de Metrologia, Qualidade e Tecnologia, Rio de Janeiro, Brazil
,
Christina Maeda Takiya Laboratório de Patologia Celular, Instituto de Ciências Biomédicas, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil
,
Oswaldo Saback Junior Departamento de Cirurgia, Hospital Universitário Clementino Fraga Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil
,
Mario Bianco Departamento de Cirurgia, Hospital Universitário Clementino Fraga Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil
,
Antonio Palumbo Junior Programa de Pesquisa em Biologia Celular e do Desenvolvimento, Instituto de Ciências Biomédicas, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil
,
Luiz Eurico Nasciutti Programa de Pesquisa em Biologia Celular e do Desenvolvimento, Instituto de Ciências Biomédicas, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil
,
Luciana Bueno Ferreira Instituto Nacional do Câncer, Programa de Carcinogênese Molecular, Rio de Janeiro, Brazil
,
Etel Rodrigues Pereira Gimba Universidade Federal Fluminense, Instituto de Humanidades e Saúde, Departamento Interdisciplinar, Rio das Ostras, Brazil; Instituto Nacional de Câncer, Programa de Carcinogênese Molecular, Rio de Janeiro, Brazil
&
Radovan Borojevic Excellion Biomedical Services, Petrópolis, Rio de Janeiro, Brazil
 show all
Pages 1076-1085 | Received 25 Feb 2013, Accepted 31 May 2013, Published online: 20 Sep 2013

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Junyu Zhou, Xiaogang Yang, Peng Song, Hongwei Wang & Xiumei Wang. (2019) HOXC6 in the prognosis of prostate cancer. Artificial Cells, Nanomedicine, and Biotechnology 47:1, pages 2715-2720.
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Articles from other publishers (29)

Dilara Ataseven, Ayşegül Öztürk, Mustafa Özkaraca & Ziad Joha. (2023) Anticancer activity of lycopene in HT-29 colon cancer cell line. Medical Oncology 40:5.
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Vittoria Rago & Silvia Di Agostino. (2023) Novel Insights into the Role of the Antioxidants in Prostate Pathology. Antioxidants 12:2, pages 289.
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Nikolina Vrdoljak. (2022) Carotenoids and Carcinogenesis: Exploring the Antioxidant and Cell Signaling Roles of Carotenoids in the Prevention of Cancer. Critical Reviews™ in Oncogenesis 27:3, pages 1-13.
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Joanna Dulińska-Litewka, Yoav Sharoni, Przemysław Hałubiec, Agnieszka Łazarczyk, Oskar Szafrański, James A. McCubrey, Bartosz Gąsiorkiewicz, Piotr Laidler & Torsten Bohn. (2021) Recent Progress in Discovering the Role of Carotenoids and Their Metabolites in Prostatic Physiology and Pathology with a Focus on Prostate Cancer—A Review—Part I: Molecular Mechanisms of Carotenoid Action. Antioxidants 10:4, pages 585.
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Poorigali Raghavendra-Rao Sowmya, Rudrappa Ambedkar & Rangaswamy Lakshminarayana. 2020. Handbook of Oxidative Stress in Cancer: Mechanistic Aspects. Handbook of Oxidative Stress in Cancer: Mechanistic Aspects 1 20 .
Rim Gheribi & Khaoula Khwaldia. 2021. Nutraceuticals and Cancer Signaling. Nutraceuticals and Cancer Signaling 39 60 .
Mirele da Silveira Vasconcelos, Luciana Maia Nogueira de Oliveira, Diana Célia Sousa Nunes-Pinheiro, Carolina de Araújo Viana, Ayrles Fernanda Brandão da Silva, Ana Débora Nunes Pinheiro, Semíramis Silva Santos, Joanna de Freitas Rocha, Erika Freitas Mota, Seid Mahdi Jafari, Ana Sanches Silva, Seyed Mohammad Nabavi & Dirce Fernandes de Melo. 2021. Nutraceuticals and Cancer Signaling. Nutraceuticals and Cancer Signaling 201 257 .
Mahdi Mirahmadi, Shayan Azimi-Hashemi, Ehsan Saburi, Hossein Kamali, Mandana Pishbin & Farzin Hadizadeh. (2020) Potential inhibitory effect of lycopene on prostate cancer. Biomedicine & Pharmacotherapy 129, pages 110459.
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Joe L RowlesIIIIII, Joshua W Smith, Catherine C Applegate, Miller Rita J, Matthew A Wallig, Amandeep Kaur, Jesus N SarolJrJr, Salma Musaad, Steven K Clinton, William D O'Brien & John W ErdmanJrJr. (2020) Dietary Tomato or Lycopene Do Not Reduce Castration-Resistant Prostate Cancer Progression in a Murine Model. The Journal of Nutrition 150:7, pages 1808-1817.
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Renata Rivera-Madrid, Victor Manuel Carballo-Uicab, Yair Cárdenas-Conejo, Margarita Aguilar-Espinosa & Ramamoorthy Siva. 2020. Carotenoids: Properties, Processing and Applications. Carotenoids: Properties, Processing and Applications 1 40 .
Dwayne Tucker, Melisa Anderson, Fabian Miller, Kurt Vaz, Lennox Anderson-Jackson & Donovan McGrowder. 2019. Antioxidants. Antioxidants.
Alok Ranjan, Sharavan Ramachandran, Nehal Gupta, Itishree Kaushik, Stephen Wright, Suyash Srivastava, Hiranmoy Das, Sangeeta Srivastava, Sahdeo Prasad & Sanjay K. Srivastava. (2019) Role of Phytochemicals in Cancer Prevention. International Journal of Molecular Sciences 20:20, pages 4981.
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Nathalia da Costa Pereira Soares, Monique de Barros Elias, Clara Lima Machado, Bruno Boquimpani Trindade, Radovan Borojevic & Anderson Junger Teodoro. (2019) Comparative Analysis of Lycopene Content from Different Tomato-Based Food Products on the Cellular Activity of Prostate Cancer Cell Lines. Foods 8:6, pages 201.
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Monique de Barros Elias, Felipe Leite Oliveira, Fatima Costa Rodrigues Guma, Renata Brum Martucci, Radovan Borojevic & Anderson Junger Teodoro. (2019) Lycopene inhibits hepatic stellate cell activation and modulates cellular lipid storage and signaling. Food & Function 10:4, pages 1974-1984.
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Ping Chen, Shina Xu & Jinlong Qu. (2017) Lycopene Protects Keratinocytes Against UVB Radiation‐Induced Carcinogenesis via Negative Regulation of FOXO3a Through the mTORC2/AKT Signaling Pathway. Journal of Cellular Biochemistry 119:1, pages 366-377.
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Lynnette R. Ferguson, Helen Chen, Andrew R. Collins, Marisa Connell, Giovanna Damia, Santanu Dasgupta, Meenakshi Malhotra, Alan K. Meeker, Amedeo Amedei, Amr Amin, S. Salman Ashraf, Katia Aquilano, Asfar S. Azmi, Dipita Bhakta, Alan Bilsland, Chandra S. Boosani, Sophie Chen, Maria Rosa Ciriolo, Hiromasa Fujii, Gunjan Guha, Dorota Halicka, William G. Helferich, W. Nicol Keith, Sulma I. Mohammed, Elena Niccolai, Xujuan Yang, Kanya Honoki, Virginia R. Parslow, Satya Prakash, Sarallah Rezazadeh, Rodney E. Shackelford, David Sidransky, Phuoc T. Tran, Eddy S. Yang & Christopher A. Maxwell. (2015) Genomic instability in human cancer: Molecular insights and opportunities for therapeutic attack and prevention through diet and nutrition. Seminars in Cancer Biology 35, pages S5-S24.
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R Niranjana, R Gayathri, Stephen Nimish Mol, T Sugawara, T Hirata, K Miyashita & P Ganesan. (2015) Carotenoids modulate the hallmarks of cancer cells. Journal of Functional Foods 18, pages 968-985.
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Jiqian Xu, Houxiang Hu, Bin Chen, Rongchuan Yue, Zhou Zhou, Yin Liu, Shuang Zhang, Lei Xu, Huan Wang & Zhengping Yu. (2015) Lycopene Protects against Hypoxia/Reoxygenation Injury by Alleviating ER Stress Induced Apoptosis in Neonatal Mouse Cardiomyocytes. PLOS ONE 10:8, pages e0136443.
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Hyemin Choi & Dong Gun Lee. (2015) Lycopene induces apoptosis in Candida albicans through reactive oxygen species production and mitochondrial dysfunction. Biochimie 115, pages 108-115.
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Hoon Young Kong & Jonghoe Byun. (2015) Screening and Characterization of a Novel RNA Aptamer That Specifically Binds to Human Prostatic Acid Phosphatase and Human Prostate Cancer Cells. Molecules and Cells 38:2, pages 171-179.
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Misaki Ono, Mikako Takeshima & Shuji Nakano. 2015. Mechanism of the Anticancer Effect of Phytochemicals. Mechanism of the Anticancer Effect of Phytochemicals 139 166 .
Nathalia da Costa Pereira Soares, Anderson Junger Teodoro, Felipe Leite Oliveira, Christina Maeda Takiya, Antonio Palumbo Junior, Luiz Eurico Nasciutti, Priscila Falagan Lotsch, José Mauro Granjeiro, Luciana Bueno Ferreira, Etel Rodrigues Pereira Gimba & Radovan Borojevic. (2014) Lycopene induce apoptosis in human prostate cells and alters the expression of Bax and Bcl-2 genes. LWT - Food Science and Technology 59:2, pages 1290-1297.
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W. Merkle. (2014) Prostatakarzinomprophylaxe durch NahrungsergänzungsmittelProstate cancer prophylaxis by dietary supplements. Der Urologe 53:11, pages 1610-1619.
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Simone Mariani, Luana Lionetto, Michele Cavallari, Andrea Tubaro, Debora Rasio, Cosimo De Nunzio, Gena Hong, Marina Borro & Maurizio Simmaco. (2014) Low Prostate Concentration of Lycopene Is Associated with Development of Prostate Cancer in Patients with High-Grade Prostatic Intraepithelial Neoplasia. International Journal of Molecular Sciences 15:1, pages 1433-1440.
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