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Original Articles

Ellagic Acid Induces Novel and Atypical PKC Isoforms and Promotes Caspase-3 Dependent Apoptosis by Blocking Energy Metabolism

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Pages 675-681 | Received 27 May 2013, Accepted 02 Dec 2013, Published online: 26 Feb 2014

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Shaimaa M. Badr-Eldin, Hibah M. Aldawsari, Usama A. Fahmy, Osama A. A. Ahmed, Nabil A. Alhakamy, Omar D. Al-hejaili, Alhanoof A. Alhassan, Ghadeer A. Ammari, Shouq I. Alhazmi, Raghad M. Alawadi, Rana Bakhaidar, Abdulmohsen J. Alamoudi, Thikryat Neamatallah & Singkome Tima. (2022) Optimized Apamin-Mediated Nano-Lipidic Carrier Potentially Enhances the Cytotoxicity of Ellagic Acid against Human Breast Cancer Cells. International Journal of Molecular Sciences 23:16, pages 9440.
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Ammara Riaz, Rabia Zara, Gul Bushra, Nazia Kanwal, Ayesha Sadiqa, Farzana Shareef, Iqra Sarfraz, Muhammad Ajmal Shah, Ilknur Ucak, Shazia Anwer Bukhari & Azhar Rasul. 2022. The Role of Phytonutrients in Metabolic Disorders. The Role of Phytonutrients in Metabolic Disorders 237 290 .
Mateusz Pieróg, Katarzyna Socała, Elżbieta Wyska, Ewa Poleszak & Piotr Wlaź. (2021) Effect of Ellagic Acid on Seizure Threshold in Two Acute Seizure Tests in Mice. Molecules 26:16, pages 4841.
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Venkatasubramanian Aishwarya, Solairaja Solaipriya & Venkatabalasubramanian Sivaramakrishnan. (2020) Role of ellagic acid for the prevention and treatment of liver diseases. Phytotherapy Research 35:6, pages 2925-2944.
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Alam ZebAlam Zeb. 2021. Phenolic Antioxidants in Foods: Chemistry, Biochemistry and Analysis. Phenolic Antioxidants in Foods: Chemistry, Biochemistry and Analysis 413 434 .
Adil Farooq Wali, Jayachithra Ramakrishna Pillai, Maryam Razmpoor, Salma Jabnoun, Imra Akbar, Saiema Rasool, Azher Arafah, Andleeb Khan, Rukhsana Akhter & Sabhiya Majid. 2020. Therapeutic Applications of Honey and its Phytochemicals. Therapeutic Applications of Honey and its Phytochemicals 31 52 .
Tamires Rocha Falcão, Aurigena Antunes de Araújo, Luiz Alberto Lira Soares, Iuri Brilhante de Farias, Wliana Alves Viturino da Silva, Magda Rhayanny Assunção Ferreira, Raimundo Fernandes de Araújo Jr, Juliana Silva de Medeiros, Maria Luiza Diniz de Sousa Lopes & Gerlane Coelho Bernardo Guerra. (2019) Libidibia ferrea Fruit Crude Extract and Fractions Show Anti-Inflammatory, Antioxidant, and Antinociceptive Effect In Vivo and Increase Cell Viability In Vitro . Evidence-Based Complementary and Alternative Medicine 2019, pages 1-14.
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Mohammad Shavez Khan, Faizan Abul Qais & Iqbal Ahmad. 2019. New Look to Phytomedicine. New Look to Phytomedicine 179 201 .
Alam Zeb. (2018) Ellagic acid in suppressing in vivo and in vitro oxidative stresses. Molecular and Cellular Biochemistry 448:1-2, pages 27-41.
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Alexandra L. Boehning, Safia A. Essien, Erica L. Underwood, Pramod K. Dash & Darren Boehning. (2018) Cell type-dependent effects of ellagic acid on cellular metabolism. Biomedicine & Pharmacotherapy 106, pages 411-418.
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Jinlu Zhao, Guodong Li, Wanlan Bo, Yuhui Zhou, Shuwei Dang, Jiufeng Wei, Xinglong Li & Ming Liu. (2017) Multiple effects of ellagic acid on human colorectal carcinoma cells identified by gene expression profile analysis. International Journal of Oncology.
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Omran Karmach & Manuela Martins-Green. 2016. Complementary and Alternative Medicines in Prostate Cancer. Complementary and Alternative Medicines in Prostate Cancer 181 196 .
Laura Porcza, Claire Simms & Mridula Chopra. (2016) Honey and Cancer: Current Status and Future Directions. Diseases 4:4, pages 30.
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Akhilendra Kumar Maurya & Manjula Vinayak. (2016) PI-103 and Quercetin Attenuate PI3K-AKT Signaling Pathway in T- Cell Lymphoma Exposed to Hydrogen Peroxide. PLOS ONE 11:8, pages e0160686.
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Marcos Roberto de Oliveira. (2016) The Effects of Ellagic Acid upon Brain Cells: A Mechanistic View and Future Directions. Neurochemical Research 41:6, pages 1219-1228.
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Sudha Mishra & Manjula Vinayak. (2015) Role of ellagic acid in regulation of apoptosis by modulating novel and atypical PKC in lymphoma bearing mice. BMC Complementary and Alternative Medicine 15:1.
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Akhilendra Kumar Maurya & Manjula Vinayak. (2015) Modulation of PKC signaling and induction of apoptosis through suppression of reactive oxygen species and tumor necrosis factor receptor 1 (TNFR1): key role of quercetin in cancer prevention. Tumor Biology 36:11, pages 8913-8924.
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Souvik Sarkar, Asim A. Siddiqui, Somnath Mazumder, Rudranil De, Shubhra J. Saha, Chinmoy Banerjee, Mohd. S. Iqbal, Susanta Adhikari, Athar Alam, Siddhartha Roy & Uday Bandyopadhyay. (2015) Ellagic Acid, a Dietary Polyphenol, Inhibits Tautomerase Activity of Human Macrophage Migration Inhibitory Factor and Its Pro-inflammatory Responses in Human Peripheral Blood Mononuclear Cells. Journal of Agricultural and Food Chemistry 63:20, pages 4988-4998.
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Daniela Beck da Silva Marcondes, Cristiane Loiva Reichert, Lucas Ferrari de Andrade, Cid Aimbiré de Moraes Santos & Almeriane Maria Weffort-Santos. (2014) Cytotoxicity and apoptogenic effects of Lafoensia pacari. Journal of Ethnopharmacology 157, pages 243-250.
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