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Nutrition and Cancer Volume 66, 2014 - Issue 4
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Original Articles

Combined Treatment with Epimedium koreanum Nakai Extract and Gefitinib Overcomes Drug Resistance Caused by T790M Mutation in Non-Small Cell Lung Cancer Cells

Jie SongKey Laboratory of Delivery Systems of Chinese Meteria Medica, Jiangsu Provincial Academy of Chinese Medicine, Jiangsu, Nanjing, China
,
Rongling ZhongKey Laboratory of Delivery Systems of Chinese Meteria Medica, Jiangsu Provincial Academy of Chinese Medicine, Jiangsu, Nanjing, China
,
Houcai HuangKey Laboratory of Delivery Systems of Chinese Meteria Medica, Jiangsu Provincial Academy of Chinese Medicine, Jiangsu, Nanjing, China
,
Zhenhai ZhangKey Laboratory of Delivery Systems of Chinese Meteria Medica, Jiangsu Provincial Academy of Chinese Medicine, Jiangsu, Nanjing, China
,
Dongmei DingKey Laboratory of Delivery Systems of Chinese Meteria Medica, Jiangsu Provincial Academy of Chinese Medicine, Jiangsu, Nanjing, China
,
Hongmei YanKey Laboratory of Delivery Systems of Chinese Meteria Medica, Jiangsu Provincial Academy of Chinese Medicine, Jiangsu, Nanjing, China
,
E SunKey Laboratory of Delivery Systems of Chinese Meteria Medica, Jiangsu Provincial Academy of Chinese Medicine, Jiangsu, Nanjing, China
&
Xiaobin JiaKey Laboratory of Delivery Systems of Chinese Meteria Medica, Jiangsu Provincial Academy of Chinese Medicine, Jiangsu, Nanjing, ChinaCorrespondence[email protected]
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Pages 682-689 | Received 16 Jul 2013, Accepted 08 Jan 2014, Published online: 16 Apr 2014

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Hyun-Ji Park & Shin-Hyung Park. (2023) The Ethanolic Extract of Trichosanthes Kirilowii Root Exerts anti-Cancer Effects in Human Non-Small Cell Lung Cancer Cells Resistant to EGFR TKI. Nutrition and Cancer 75:1, pages 376-387.
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Hao Wu, Qingxiang Zhong, Rongling Zhong, Houcai Huang, Zhi Xia, Zhongcheng Ke, Zhenhai Zhang, Jie Song & Xiaobin Jia. (2016) Preparation and antitumor evaluation of self-assembling oleanolic acid-loaded Pluronic P105/d-α-tocopheryl polyethylene glycol succinate mixed micelles for non-small-cell lung cancer treatment. International Journal of Nanomedicine 11, pages 6337-6352.
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Gisella Campanelli, Rabab Al Deabel, Anand Puaar, Lakshmi Sirisha Devarakonda, Prashanth Parupathi, Joyce Zhang, Noah Waxner, Ching Yang, Avinash Kumar & Anait S. Levenson. (2023) Molecular Efficacy of Gnetin C as Dual‐Targeted Therapy for Castrate‐Resistant Prostate Cancer. Molecular Nutrition & Food Research 67:24.
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Juan Xia, Jun-Nan Hu, Zi Wang, En-Bo Cai, Shen Ren, Ying-Ping Wang, Xiu-Juan Lei & Wei Li. (2022) Based on network pharmacology and molecular docking to explore the protective effect of Epimedii Folium extract on cisplatin-induced intestinal injury in mice. Frontiers in Pharmacology 13.
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Hiu Lee, Mingjing Meng, Yulong Liu, Tao Su & Hiu Kwan. (2021) Medicinal herbs and bioactive compounds overcome the drug resistance to epidermal growth factor receptor inhibitors in non‑small cell lung cancer (Review). Oncology Letters 22:3.
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Chao Huang, Zhihua Li, Jinglin Zhu, Xuetong Chen, Yuanyuan Hao, Ruijie Yang, Ruifei Huang, Jun Zhou, Zhenzhong Wang, Wei Xiao, Chunli Zheng & Yonghua Wang. (2021) Systems pharmacology dissection of Epimedium targeting tumor microenvironment to enhance cytotoxic T lymphocyte responses in lung cancer. Aging 13:2, pages 2912-2940.
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Xiuling Li, Shunung Liang, Chee Hwee Tan, Shuwen Cao, Xiaoding Xu, Phei Er Saw & Wei Tao. (2021) Nanocarriers in the Enhancement of Therapeutic Efficacy of Natural Drugs. BIO Integration 2:2.
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Hao Wu, Yuan Luo, Dongmei Xu, Xue Ke & Tianyuan Ci. (2020) Low molecular weight heparin modified bone targeting liposomes for orthotopic osteosarcoma and breast cancer bone metastatic tumors. International Journal of Biological Macromolecules 164, pages 2583-2597.
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Ya-Sai Sun, Kiran Thakur, Fei Hu, Jian-Guo Zhang & Zhao-Jun Wei. (2020) Icariside II inhibits tumorigenesis via inhibiting AKT/Cyclin E/ CDK 2 pathway and activating mitochondria-dependent pathway. Pharmacological Research 152, pages 104616.
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Jun Li, Xiao‐Hui Wang, Jing Hu, Meng Shi, Lu Zhang & Hong Chen. (2019) Combined treatment with N‐acetylcysteine and gefitinib overcomes drug resistance to gefitinib in NSCLC cell line. Cancer Medicine 9:4, pages 1495-1502.
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Ji Yun Jung, Sang Mi Park, Hae Li Ko, Jong Rok Lee, Chung A Park, Sung Hui Byun, Sae Kwang Ku, Il Je Cho & Sang Chan Kim. (2018) Epimedium koreanum Ameliorates Oxidative Stress-Mediated Liver Injury by Activating Nuclear Factor Erythroid 2-Related Factor 2 . The American Journal of Chinese Medicine 46:02, pages 469-488.
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Xiang Dong Su, Wei Li, Ji Eun Kim, Seo Young Yang, Jin Yeul Ma & Young Ho Kim. (2017) Prenyl-flavonoids from Epimedium koreanum Nakai and their soluble epoxide hydrolase and tyrosinase inhibitory activities. Medicinal Chemistry Research 26:11, pages 2761-2767.
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Jie Song, Liang Feng, Rongling Zhong, Zhi Xia, Li Zhang, Li Cui, Hongmei Yan, Xiaobin Jia & Zhenhai Zhang. (2017) Icariside II inhibits the EMT of NSCLC cells in inflammatory microenvironment via down-regulation of Akt/NF-κB signaling pathway. Molecular Carcinogenesis 56:1, pages 36-48.
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Hui-Li Tan, Kok-Gan Chan, Priyia Pusparajah, Surasak Saokaew, Acharaporn Duangjai, Learn-Han Lee & Bey-Hing Goh. (2016) Anti-Cancer Properties of the Naturally Occurring Aphrodisiacs: Icariin and Its Derivatives. Frontiers in Pharmacology 7.
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Sheng-Yi Lin, Hsiu-Hui Chang, Yi-Hua Lai, Ching-Hsiung Lin, Min-Hsuan Chen, Gee-Chen Chang, Meng-Feng Tsai & Jeremy J. W. Chen. (2015) Digoxin Suppresses Tumor Malignancy through Inhibiting Multiple Src-Related Signaling Pathways in Non-Small Cell Lung Cancer. PLOS ONE 10:5, pages e0123305.
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