324
Views
40
CrossRef citations to date
0
Altmetric
Original Articles

Liquiritigenin Potentiates the Inhibitory Effects of Cisplatin on Invasion and Metastasis Via Downregulation MMP-2/9 and PI3 K/AKT Signaling Pathway in B16F10 Melanoma Cells and Mice Model

, , , , , , & show all
Pages 761-770 | Received 05 Nov 2013, Accepted 23 Mar 2015, Published online: 15 May 2015

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (1)

Xueqin Li, Qianqian Song, Xueru Guo, Limin Wang, Qicheng Zhang, Limin Cao, Yinghui Ren, Xiang Wu, Zhaowei Meng & Ke Xu. (2020) The Metastasis Potential Promoting Capacity of Cancer-Associated Fibroblasts Was Attenuated by Cisplatin via Modulating KRT8. OncoTargets and Therapy 13, pages 2711-2723.
Read now

Articles from other publishers (39)

Rihui Li, Yongwei Chen, Yuanfang Cheng, Yajuan Wang, Qing Deng & Bin Wang. (2024) Inhibitory Effect of Tanshinone IIA Extracted from Radix Salviae miltiorrhizae on Melanoma B16F10 Cells . Journal of Biobased Materials and Bioenergy 18:5, pages 943-949.
Crossref
Zhuxian Wang, Hongkai Chen, Tao Liang, Yi Hu, Yaqi Xue, Yufan Wu, Quanfu Zeng, Yixin Zheng, Yinglin Guo, Zeying Zheng, Dan Zhai, Peiyi Liang, Chunyan Shen, Cuiping Jiang, Li Liu, Qun Shen, Hongxia Zhu & Qiang Liu. (2023) The implications of lipid mobility, drug-enhancers (surfactants)-skin interaction, and TRPV1 activation on licorice flavonoid permeability. Drug Delivery and Translational Research 14:6, pages 1582-1600.
Crossref
Parvin Zulfugarova, Tayebeh Zivari-Ghader, Sevinj Maharramova, Elham Ahmadian, Aziz Eftekhari, Rovshan Khalilov, Vugar Ali Turksoy, Gvozden Rosić & Dragica Selakovic. (2023) A mechanistic review of pharmacological activities of homeopathic medicine licorice against neural diseases. Frontiers in Neuroscience 17.
Crossref
Qi Lu, Lin‐feng Zou, Yuan‐zhen Gao, Ting Ye, Meng‐jiao Li, Yu‐Kun Zhang, Bing Liang, Wenshe Sun & Dong‐ming Xing. (2022) Liquiritigenin reverses skin aging by inhibiting UV‐induced mitochondrial uncoupling and excessive energy consumption. Journal of Cosmetic Dermatology 22:3, pages 1017-1030.
Crossref
Zhuxian Wang, Yi Hu, Yaqi Xue, Zhaoming Zhu, Yufan Wu, Quanfu Zeng, Yuan Wang, Haoyang Han, Haixiang Zhang, Chunyan Shen, Kuiyan Yi, Cuiping Jiang, Li Liu, Hongxia Zhu, Hui Li, Qiang Liu & Qun Shen. (2022) Mechanism insight on licorice flavonoids release from Carbopol hydrogels: Role of “release steric hindrance” and drug solubility in the release medium. European Journal of Pharmaceutical Sciences 179, pages 106307.
Crossref
Hardeep Singh Tuli, Vivek Kumar Garg, Jinit K Mehta, Ginpreet Kaur, Ranjan K Mohapatra, Kuldeep Dhama, Katrin Sak, Ajay Kumar, Mehmet Varol, Diwakar Aggarwal, Uttpal Anand, Jagjit Kaur, Ross Gillan, Gautam Sethi & Anupam Bishayee. (2022) Licorice (Glycyrrhiza glabra L.)-Derived Phytochemicals Target Multiple Signaling Pathways to Confer Oncopreventive and Oncotherapeutic Effects. OncoTargets and Therapy Volume 15, pages 1419-1448.
Crossref
Yu-Jen Kuo, Jin-Kuo Pei & Wen-Wan Chao. (2022) Pharmacological and Chemical Potential of Spiranthes sinensis (Orchidaceae): A Narrative Review. Plants 11:13, pages 1692.
Crossref
Meng Zhou, Yanpeng Dai, Yong Ma, Yi Yan, Min Hua, Qi Gao, Xue Geng & Qian Zhou. (2022) Protective Effects of Liquiritigenin against Cisplatin-Induced Nephrotoxicity via NRF2/SIRT3-Mediated Improvement of Mitochondrial Function. Molecules 27:12, pages 3823.
Crossref
Weiwei Wang, Weiliang Gu, Chao He, Tong Zhang, Yao Shen & Yiqiong Pu. (2022) Bioactive components of Banxia Xiexin Decoction for the treatment of gastrointestinal diseases based on flavor-oriented analysis. Journal of Ethnopharmacology 291, pages 115085.
Crossref
Neetu Bhari, Robert A. Schwaertz, Zoe Apalla, Gabriel Salerni, Bengu Nisa Akay, Anant Patil, Stephan Grabbe & Mohamad Goldust. (2021) Effect of estrogen in malignant melanoma. Journal of Cosmetic Dermatology 21:5, pages 1905-1912.
Crossref
Saabira Banu Sahubar Sadik, Prathibha Sivaprakasam, Nishanthi Ramasami & Ashok Kumar Pandurangan. 2022. Handbook of Research on Natural Products and Their Bioactive Compounds as Cancer Therapeutics. Handbook of Research on Natural Products and Their Bioactive Compounds as Cancer Therapeutics 45 71 .
Chang Liu, Dai Yuan, Chi Zhang, Ye Tao, Ying Meng, Mengli Jin, Wu Song, Bingmei Wang & Lin Wei. (2022) Liquiritin Alleviates Depression-Like Behavior in CUMS Mice by Inhibiting Oxidative Stress and NLRP3 Inflammasome in Hippocampus. Evidence-Based Complementary and Alternative Medicine 2022, pages 1-10.
Crossref
Glenise Bierhalz Voss, Ana L.S. Oliveira, Elisabete Maria da Cruz Alexandre & Manuela Estevez Pintado. 2022. Technologies to Recover Polyphenols from AgroFood By-products and Wastes. Technologies to Recover Polyphenols from AgroFood By-products and Wastes 1 23 .
Luigi Battaglia, Anna Scomparin, Chiara Dianzani, Paola Milla, Elisabetta Muntoni, Silvia Arpicco & Roberta Cavalli. (2021) Nanotechnology Addressing Cutaneous Melanoma: The Italian Landscape. Pharmaceutics 13:10, pages 1617.
Crossref
Jia Chen, Lin-Fu Li, Xiao-Ru Hu, Feng Wei & Shuangcheng Ma. (2021) Network Pharmacology-Based Strategy for Elucidating the Molecular Basis Forthe Pharmacologic Effects of Licorice (Glycyrrhiza spp.). Frontiers in Pharmacology 12.
Crossref
Zhixin Zhang, Lin Yang, Jiaming Hou, Shaokai Tian & Ying Liu. (2021) Molecular mechanisms underlying the anticancer activities of licorice flavonoids. Journal of Ethnopharmacology 267, pages 113635.
Crossref
M. Zubair, S. Wang & N. Ali. (2021) Advanced Approaches to Breast Cancer Classification and Diagnosis. Frontiers in Pharmacology 11.
Crossref
Banele Ndlovu, Maryna De Kock, Jeremy Klaasen & Farzana Rahiman. (2021) In Vitro Comparison of the Anti-Proliferative Effects of Galenia africana on Human Skin Cell Lines. Scientia Pharmaceutica 89:1, pages 12.
Crossref
Fang Liang, Hao Zhang, Hui Gao, Duo Cheng, Nan Zhang, Jie Du, Junmin Yue, Peng Du, Beibei Zhao & Lu Yin. (2020) Liquiritigenin decreases tumorigenesis by inhibiting DNMT activity and increasing BRCA1 transcriptional activity in triple-negative breast cancer. Experimental Biology and Medicine 246:4, pages 459-466.
Crossref
Su-Tze Chou, Bing-Ying Ho, Yu-Ting Tai, Chun-Jen Huang & Wen-Wan Chao. (2020) Bidirect effects from cisplatin combine with rosmarinic acid (RA) or hot water extracts of Glechoma hederacea (HWG) on renal cancer cells. Chinese Medicine 15:1.
Crossref
Chitra Joseph, Mansour Alsaleem, Nnamdi Orah, Pavan L. Narasimha, Islam M. Miligy, Sasagu Kurozumi, Ian O. Ellis, Nigel P. Mongan, Andrew R. Green & Emad A. Rakha. (2020) Elevated MMP9 expression in breast cancer is a predictor of shorter patient survival. Breast Cancer Research and Treatment 182:2, pages 267-282.
Crossref
Soraya Sajadimajd, Roodabeh Bahramsoltani, Amin Iranpanah, Jayanta Kumar Patra, Gitishree Das, Sushanto Gouda, Roja Rahimi, Elnaz Rezaeiamiri, Hui Cao, Francesca Giampieri, Maurizio Battino, Rosa Tundis, Maria G. Campos, Mohammad Hosein Farzaei & Jianbo Xiao. (2020) Advances on Natural Polyphenols as Anticancer Agents for Skin Cancer. Pharmacological Research 151, pages 104584.
Crossref
Simbulan-Rosenthal, Dougherty, Vakili, Ferraro, Kuo, Alobaidi, Aljehane, Gaur, Sykora, Glasgow, Agarwal & Rosenthal. (2019) CRISPR-Cas9 Knockdown and Induced Expression of CD133 Reveal Essential Roles in Melanoma Invasion and Metastasis. Cancers 11:10, pages 1490.
Crossref
Meimei Chen, Jingru Zhu, Jie Kang, Xinmei Lai, Yuxing Gao, Huijuan Gan & Fafu Yang. (2019) Exploration in the Mechanism of Action of Licorice by Network Pharmacology. Molecules 24:16, pages 2959.
Crossref
Hsin‐Yu Chen, Yi‐Wen Jiang, Chao‐Lin Kuo, Tzong‐Der Way, Yu‐Cheng Chou, Yuan‐Shiun Chang & Jing‐Gung Chung. (2018) Chrysin inhibit human melanoma A375.S2 cell migration and invasion via affecting MAPK signaling and NF‐κB signaling pathway in vitro. Environmental Toxicology 34:4, pages 434-442.
Crossref
Yi‐Wen Jiang, Hsin‐Yu Cheng, Chao‐Lin Kuo, Tzong‐Der Way, Jin‐Cherng Lien, Fu‐Shin Chueh, Yun‐Lian Lin & Jing‐Gung Chung. (2018) Tetrandrine inhibits human brain glioblastoma multiforme GBM 8401 cancer cell migration and invasion in vitro. Environmental Toxicology 34:4, pages 364-374.
Crossref
Fan-Chun Meng & Jun-Kai Lin. (2019) Liquiritigenin Inhibits Colorectal Cancer Proliferation, Invasion, and Epithelial-to-Mesenchymal Transition by Decreasing Expression of Runt-Related Transcription Factor 2. Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics 27:2, pages 139-146.
Crossref
Rossella Salemi, Luca Falzone, Gabriele Madonna, Jerry Polesel, Diana Cinà, Domenico Mallardo, Paolo A. Ascierto, Massimo Libra & Saverio Candido. (2018) MMP-9 as a Candidate Marker of Response to BRAF Inhibitors in Melanoma Patients With BRAFV600E Mutation Detected in Circulating-Free DNA. Frontiers in Pharmacology 9.
Crossref
Gong Deuk Bae, Eun-Young Park, Dong Jae Baek, Hee-Sook Jun & Yoon Sin Oh. (2018) Liquiritigenin prevents palmitate-induced beta-cell apoptosis via estrogen receptor-mediated AKT activation. Biomedicine & Pharmacotherapy 101, pages 348-354.
Crossref
Sheng Li, Xiu-Yin Shen, Ting Ouyang, Yuhua Qu, Tao Luo & Hua-Qiao Wang. (2017) Synergistic anticancer effect of combined crocetin and cisplatin on KYSE-150 cells via p53/p21 pathway. Cancer Cell International 17:1.
Crossref
Anna Ju, Young-Chang Cho, Ba Kim, Sewoong Lee, Hien Thi Le, Huong Vuong & Sayeon Cho. (2017) Anticancer effects of methanol extract of Myrmecodia platytyrea Becc. leaves against human hepatocellular carcinoma cells via inhibition of ERK and STAT3 signaling pathways. International Journal of Oncology.
Crossref
Kuang-Chi Lai, Yung-Ting Hsiao, Jiun-Long Yang, Yi-Shih Ma, Yi-Ping Huang, Tai-An Chiang & Jing-Gung Chung. (2017) Benzyl isothiocyanate and phenethyl isothiocyanate inhibit murine melanoma B16F10 cell migration and invasion in vitro. International Journal of Oncology 51:3, pages 832-840.
Crossref
Baoqi Duan, Tao Guo, Haoliang Sun, Rui Cai, Qinglin Rui & Zhaoqing Xi. (2017) miR-205 as a biological marker in non-small cell lung cancer. Biomedicine & Pharmacotherapy 91, pages 823-830.
Crossref
Siliang Wang, Peiliang Shen, Jinrong Zhou & Yin Lu. (2017) Diet phytochemicals and cutaneous carcinoma chemoprevention: A review. Pharmacological Research 119, pages 327-346.
Crossref
Monica Marzagalli, Marina Montagnani Marelli, Lavinia Casati, Fabrizio Fontana, Roberta Manuela Moretti & Patrizia Limonta. (2016) Estrogen Receptor β in Melanoma: From Molecular Insights to Potential Clinical Utility. Frontiers in Endocrinology 7.
Crossref
Njainday Pulo Jobe, Daniel Rösel, Barbora Dvořánková, Ondřej Kodet, Lukáš Lacina, Rosana Mateu, Karel Smetana & Jan Brábek. (2016) Simultaneous blocking of IL-6 and IL-8 is sufficient to fully inhibit CAF-induced human melanoma cell invasiveness. Histochemistry and Cell Biology 146:2, pages 205-217.
Crossref
Ruijing Tang, Yujun Xu, Feiya Ma, Jing Ren, Sunan Shen, Youwei Du, Yayi Hou & Tingting Wang. (2016) Extremely low frequency magnetic fields regulate differentiation of regulatory T cells: Potential role for ROS‐mediated inhibition on AKT. Bioelectromagnetics 37:2, pages 89-98.
Crossref
YuQing Chen, Qing Tang, JingJing Wu, Fang Zheng, LiJun Yang & Swei Sunny Hann. (2015) Inactivation of PI3-K/Akt and reduction of SP1 and p65 expression increase the effect of solamargine on suppressing EP4 expression in human lung cancer cells. Journal of Experimental & Clinical Cancer Research 34:1.
Crossref
Omer F. KuzuFelix D. NguyenMohammad A. NooryArati Sharma. (2015) Current State of Animal (Mouse) Modeling in Melanoma Research. Cancer Growth and Metastasis 8s1, pages CGM.S21214.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.