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Original Articles

Antibiotic Suppression of Intestinal Microbiota Reduces Heme-Induced Lipoperoxidation Associated with Colon Carcinogenesis in Rats

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Pages 119-125 | Received 23 Apr 2014, Accepted 07 Sep 2014, Published online: 16 Dec 2014

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Read on this site (3)

Arianna Sasso & Giovanni Latella. (2018) Role of Heme Iron in the Association Between Red Meat Consumption and Colorectal Cancer. Nutrition and Cancer 70:8, pages 1173-1183.
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Chenbo Ding, Wendong Tang, Xiaobo Fan & Guoqiu Wu. (2018) Intestinal microbiota: a novel perspective in colorectal cancer biotherapeutics. OncoTargets and Therapy 11, pages 4797-4810.
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Arianna Sasso & Giovanni Latella. (2018) Dietary components that counteract the increased risk of colorectal cancer related to red meat consumption. International Journal of Food Sciences and Nutrition 69:5, pages 536-548.
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Samuele Tardito, Serena Matis & Roberto Benelli. (2023) The Pleiotropic Effects of Gut Microbiota in Colorectal Cancer Progression: How to Turn Foes into Friends. Cancers 15:3, pages 916.
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Anaïs Mazenc, Loïc Mervant, Claire Maslo, Corinne Lencina, Valérie Bézirard, Mathilde Levêque, Ingrid Ahn, Valérie Alquier-Bacquié, Nathalie Naud, Cécile Héliès-Toussaint, Laurent Debrauwer, Sylvie Chevolleau, Françoise Guéraud, Fabrice H.F. Pierre, Vassilia Théodorou & Maïwenn Olier. (2022) Maternal heme-enriched diet promotes a gut pro-oxidative status associated with microbiota alteration, gut leakiness and glucose intolerance in mice offspring. Redox Biology 53, pages 102333.
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Sara Ristori, Francesca Scavone, Chiara Bartolozzi & Lisa Giovannelli. (2022) The comet assay for the evaluation of gut content genotoxicity: Use in human studies as an early biomarker of colon cancer risk. Mutation Research/Genetic Toxicology and Environmental Mutagenesis 878, pages 503477.
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Jing Liu, Chao Liu & Jinbo Yue. (2021) Radiotherapy and the gut microbiome: facts and fiction. Radiation Oncology 16:1.
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Liana C. Arnaud, Thierry Gauthier, Augustin Le Naour, Saleha Hashim, Nathalie Naud, Jerry W. Shay, Fabrice H. Pierre, Elisa Boutet-Robinet & Laurence Huc. (2021) Short-Term and Long-Term Carcinogenic Effects of Food Contaminants (4-Hydroxynonenal and Pesticides) on Colorectal Human Cells: Involvement of Genotoxic and Non-Genomic Mechanisms. Cancers 13:17, pages 4337.
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Andrew D. Frugé, Kristen S. Smith, Aaron J. Riviere, Rachel Tenpenny-Chigas, Wendy Demark-Wahnefried, Anna E. Arthur, William M. Murrah, William J. van der Pol, Shanese L. Jasper, Casey D. Morrow, Robert D. Arnold & Kimberly Braxton-Lloyd. (2021) A Dietary Intervention High in Green Leafy Vegetables Reduces Oxidative DNA Damage in Adults at Increased Risk of Colorectal Cancer: Biological Outcomes of the Randomized Controlled Meat and Three Greens (M3G) Feasibility Trial. Nutrients 13:4, pages 1220.
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书辰 董. (2021) The Relationship between Bile Acid Metabolism and Colorectal Polyps. Advances in Clinical Medicine 11:06, pages 2564-2571.
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Nadine Abu‐Ghazaleh, Weng Joe Chua & Vinod Gopalan. (2020) Intestinal microbiota and its association with colon cancer and red/processed meat consumption. Journal of Gastroenterology and Hepatology 36:1, pages 75-88.
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Lidia Sánchez-Alcoholado, Bruno Ramos-Molina, Ana Otero, Aurora Laborda-Illanes, Rafael Ordóñez, José Antonio Medina, Jaime Gómez-Millán & María Isabel Queipo-Ortuño. (2020) The Role of the Gut Microbiome in Colorectal Cancer Development and Therapy Response. Cancers 12:6, pages 1406.
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Yingling Liu, Yuli Cai, Si Chen, Yawen Gou, Qiaomin Wang, Mingli Zhang, Yetao Wang, Haiou Hong & Kaiguang Zhang. (2020) Analysis of Risk Factors of Gastric Low-Grade Intraepithelial Neoplasia in Asymptomatic Subjects Undergoing Physical Examination. Gastroenterology Research and Practice 2020, pages 1-9.
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Reggie Surya. (2020) Mechanistic Hypotheses on Colorectal Cancer and Red Meat Intake: A Review. IOP Conference Series: Earth and Environmental Science 426:1, pages 012176.
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Nina Seiwert, Daniel Heylmann, Solveig Hasselwander & Jörg Fahrer. (2020) Mechanism of colorectal carcinogenesis triggered by heme iron from red meat. Biochimica et Biophysica Acta (BBA) - Reviews on Cancer 1873:1, pages 188334.
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Océane C. B. Martin, Maïwenn Olier, Sandrine Ellero-Simatos, Nathalie Naud, Jacques Dupuy, Laurence Huc, Sylviane Taché, Vanessa Graillot, Mathilde Levêque, Valérie Bézirard, Cécile Héliès-Toussaint, Florence Blas Y. Estrada, Valérie Tondereau, Yannick Lippi, Claire Naylies, Lindsey Peyriga, Cécile Canlet, Anne Marie Davila, François Blachier, Laurent Ferrier, Elisa Boutet-Robinet, Françoise Guéraud, Vassilia Théodorou & Fabrice H. F. Pierre. (2019) Haem iron reshapes colonic luminal environment: impact on mucosal homeostasis and microbiome through aldehyde formation. Microbiome 7:1.
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Francesco Sofi, Monica Dinu, Giuditta Pagliai, Fabrice Pierre, Francoise Gueraud, Jildau Bowman, Philippe Gerard, Vincenzo Longo, Lisa Giovannelli, Giovanna Caderni & Carlotta de Filippo. (2019) Fecal microbiome as determinant of the effect of diet on colorectal cancer risk: comparison of meat-based versus pesco-vegetarian diets (the MeaTIc study). Trials 20:1.
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Frugé, Smith, Riviere, Demark-Wahnefried, Arthur, Murrah, Morrow, Arnold & Braxton-Lloyd. (2019) Primary Outcomes of a Randomized Controlled Crossover Trial to Explore the Effects of a High Chlorophyll Dietary Intervention to Reduce Colon Cancer Risk in Adults: The Meat and Three Greens (M3G) Feasibility Trial. Nutrients 11:10, pages 2349.
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Fariborz Mansour-Ghanaei, Gharmohammad Varshi, Farahnaz Joukar, Mohammad Taghi Ashoobi, Javad Esmaeilpour, Alireza Gharibpoor, Arash Daryakar, Roya Mansour-Ghanaei, Heydar Ali Balou, Hamid Saeidi Saedi, Sara Mavaddati & Masood Sepehrimanesh. (2019) Prevalence of pre-cancerous colon lesions in referred patients under patronage of a local relief foundation in Guilan province. Journal of Medicine and Life 12:2, pages 133-139.
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Christa Pfeifhofer-Obermair, Piotr Tymoszuk, Verena Petzer, Günter Weiss & Manfred Nairz. (2018) Iron in the Tumor Microenvironment—Connecting the Dots. Frontiers in Oncology 8.
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Océane C.B. Martin, Nathalie Naud, Sylviane Taché, Laurent Debrauwer, Sylvie Chevolleau, Jacques Dupuy, Céline Chantelauze, Denis Durand, Estelle Pujos-Guillot, Florence Blas-Y-Estrada, Christine Urbano, Gunter G.C. Kuhnle, Véronique Santé-Lhoutellier, Thierry Sayd, Didier Viala, Adeline Blot, Nathalie Meunier, Pascal Schlich, Didier Attaix, Françoise Guéraud, Valérie Scislowski, Denis E. Corpet & Fabrice H.F. Pierre. (2018) Targeting Colon Luminal Lipid Peroxidation Limits Colon Carcinogenesis Associated with Red Meat Consumption. Cancer Prevention Research 11:9, pages 569-580.
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Claire Kruger & Yuting Zhou. (2018) Red meat and colon cancer: A review of mechanistic evidence for heme in the context of risk assessment methodology. Food and Chemical Toxicology 118, pages 131-153.
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S.M.K. Gamage, Lakal Dissabandara, Alfred King-Yin Lam & Vinod Gopalan. (2018) The role of heme iron molecules derived from red and processed meat in the pathogenesis of colorectal carcinoma. Critical Reviews in Oncology/Hematology 126, pages 121-128.
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Peter Stenvinkel, Johanna Painer, Makoto Kuro-o, Miguel Lanaspa, Walter Arnold, Thomas Ruf, Paul G. Shiels & Richard J. Johnson. (2018) Novel treatment strategies for chronic kidney disease: insights from the animal kingdom. Nature Reviews Nephrology 14:4, pages 265-284.
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Edda Russo, Giovanni Bacci, Carolina Chiellini, Camilla Fagorzi, Elena Niccolai, Antonio Taddei, Federica Ricci, Maria N. Ringressi, Rossella Borrelli, Filippo Melli, Manouela Miloeva, Paolo Bechi, Alessio Mengoni, Renato Fani & Amedeo Amedei. (2018) Preliminary Comparison of Oral and Intestinal Human Microbiota in Patients with Colorectal Cancer: A Pilot Study. Frontiers in Microbiology 8.
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Stephanie Rockfield, Joseph Raffel, Radhe Mehta, Nabila Rehman & Meera Nanjundan. (2017) Iron overload and altered iron metabolism in ovarian cancer. Biological Chemistry 398:9, pages 995-1007.
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Nancy D Turner & Shannon K Lloyd. (2017) Association between red meat consumption and colon cancer: A systematic review of experimental results. Experimental Biology and Medicine 242:8, pages 813-839.
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Thomas Van Hecke, John Van Camp & Stefaan De Smet. (2017) Oxidation During Digestion of Meat: Interactions with the Diet and Helicobacter pylori Gastritis, and Implications on Human Health . Comprehensive Reviews in Food Science and Food Safety 16:2, pages 214-233.
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Camelia Papuc, Gheorghe V. Goran, Corina N. Predescu & Valentin Nicorescu. (2017) Mechanisms of Oxidative Processes in Meat and Toxicity Induced by Postprandial Degradation Products: A Review. Comprehensive Reviews in Food Science and Food Safety 16:1, pages 96-123.
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Christina Steppeler, Marianne Sødring & Jan Erik Paulsen. (2016) Colorectal Carcinogenesis in the A/J Min/+ Mouse Model is Inhibited by Hemin, Independently of Dietary Fat Content and Fecal Lipid Peroxidation Rate. BMC Cancer 16:1.
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Stefaan De Smet & Els Vossen. (2016) Meat: The balance between nutrition and health. A review. Meat Science 120, pages 145-156.
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Marion Oberli, Annaïg Lan, Nadezda Khodorova, Véronique Santé-Lhoutellier, Francine Walker, Julien Piedcoq, Anne-Marie Davila, François Blachier, Daniel Tomé, Gilles Fromentin & Claire Gaudichon. (2016) Compared with Raw Bovine Meat, Boiling but Not Grilling, Barbecuing, or Roasting Decreases Protein Digestibility without Any Major Consequences for Intestinal Mucosa in Rats, although the Daily Ingestion of Bovine Meat Induces Histologic Modifications in the Colon. The Journal of Nutrition 146:8, pages 1506-1513.
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