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Original Articles

Zapotin (5,6,2′,6′-tetramethoxyflavone) Modulates the Crosstalk Between Autophagy and Apoptosis Pathways in Cancer Cells with Overexpressed Constitutively Active PKCϵ

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Pages 290-304 | Received 16 Jan 2015, Accepted 21 Oct 2015, Published online: 04 Feb 2016

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Manami Haba, Naohito Abe, Tetsuro Kamiya, Nagisa Mizuno, Satoshi Okubo, Takao Yamaura, Hirokazu Hara & Masayoshi Oyama. (2022) Two new methoxylated flavones isolated from Casimiroa edulis La Llave and their MMP-9 inhibitory activity. Natural Product Research 36:23, pages 5959-5966.
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Jakub W. Strawa, Katarzyna Jakimiuk & Michał Tomczyk. (2021) Zapotin, a Polymethoxyflavone, with Potential Therapeutic Attributes. International Journal of Molecular Sciences 22:24, pages 13227.
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Christian Bailly. (2021) The subgroup of 2′-hydroxy-flavonoids: Molecular diversity, mechanism of action, and anticancer properties. Bioorganic & Medicinal Chemistry 32, pages 116001.
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Monica Benvenuto, Loredana Albonici, Chiara Focaccetti, Sara Ciuffa, Sara Fazi, Loredana Cifaldi, Martino Tony Miele, Fernando De Maio, Ilaria Tresoldi, Vittorio Manzari, Andrea Modesti, Laura Masuelli & Roberto Bei. (2020) Polyphenol-Mediated Autophagy in Cancer: Evidence of In Vitro and In Vivo Studies. International Journal of Molecular Sciences 21:18, pages 6635.
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Ewa Toton, Aleksandra Romaniuk, Natalia Konieczna, Johann Hofmann, Jan Barciszewski & Maria Rybczynska. (2018) Impact of PKCε downregulation on autophagy in glioblastoma cells. BMC Cancer 18:1.
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Tianyi Wang, Conghe Liu & Lili Jia. (2018) The roles of PKCs in regulating autophagy. Journal of Cancer Research and Clinical Oncology 144:12, pages 2303-2311.
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Hongwei Jiang, Yujin Ma, Liujun Fu, Jie Wang, Linlei Wang, Menglin Fan, Ke Huang, Yingyu Zhang & Huifang Peng. (2018) Influence of lipopolysaccharides on autophagy and inflammation in pancreatic islet cells of mice fed by high-fat diet. European Journal of Inflammation 16, pages 1721727X1775418.
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Wafaa Mostafa Elkady, Eman Ahmed Ibrahim, Mariam Hussein Gonaid & Farouk Kamel El Baz. (2017) Chemical Profile and Biological Activity of Casimiroa Edulis Non-Edible Fruit`s Parts. Advanced Pharmaceutical Bulletin 7:4, pages 655-660.
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