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Original Articles

Induction of Anoikis in Human Colorectal Cancer Cells by Fucoxanthinol

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Pages 1043-1052 | Received 24 Oct 2016, Accepted 20 Mar 2017, Published online: 09 Oct 2017

Keep up to date with the latest research on this topic with citation updates for this article.

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Masaru Terasaki, Shouta Takahashi, Ryuta Nishimura, Atsuhito Kubota, Hiroyuki Kojima, Tohru Ohta, Junichi Hamada, Yasuhiro Kuramitsu, Hayato Maeda, Kazuo Miyashita, Mami Takahashi & Michihiro Mutoh. (2022) A Marine Carotenoid of Fucoxanthinol Accelerates the Growth of Human Pancreatic Cancer PANC-1 Cells. Nutrition and Cancer 74:1, pages 357-371.
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Reo Yokoyama, Hiroyuki Kojima, Rie Takai, Tohru Ohta, Hayato Maeda, Kazuo Miyashita, Michihiro Mutoh & Masaru Terasaki. (2021) Effects of CLIC4 on Fucoxanthinol-Induced Apoptosis in Human Colorectal Cancer Cells. Nutrition and Cancer 73:5, pages 889-898.
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Articles from other publishers (19)

Vandana Joshi & Navneeta Bharadvaja. (2023) Current Prospects and Clinical Status of Microalgae Derived Chemotherapeutics. Revista Brasileira de Farmacognosia 33:3, pages 445-470.
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Jingbing Liu, Guanzheng Lu, Can Liang, Yifan Tian & Ziyu Jiang. (2023) Roles of anoikis in colorectal cancer therapy and the assessment of anoikis-regulatory molecules as therapeutic targets. Pathology - Research and Practice 241, pages 154256.
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Yunhua Fu, Dong Xie, Yinghao Zhu, Xinyue Zhang, Hao Yue, Kai Zhu, Zifeng Pi & Yulin Dai. (2022) Anti-colorectal cancer effects of seaweed-derived bioactive compounds. Frontiers in Medicine 9.
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Nur Akmal Solehah Din, ‘Ain Sajda Mohd Alayudin, Noor-Soffalina Sofian-Seng, Hafeedza Abdul Rahman, Noorul Syuhada Mohd Razali, Seng Joe Lim & Wan Aida Wan Mustapha. (2022) Brown Algae as Functional Food Source of Fucoxanthin: A Review. Foods 11:15, pages 2235.
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Ayaka Yasuda, Momoka Wagatsuma, Wataru Murase, Atsuhito Kubota, Hiroyuki Kojima, Tohru Ohta, Junichi Hamada, Hayato Maeda & Masaru Terasaki. (2022) Fucoxanthinol Promotes Apoptosis in MCF-7 and MDA-MB-231 Cells by Attenuating Laminins–Integrins Axis. Onco 2:3, pages 145-163.
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Ningning Han, Jianjiang Li & Xia Li. (2022) Natural Marine Products: Anti-Colorectal Cancer In Vitro and In Vivo. Marine Drugs 20:6, pages 349.
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Charly Gutierrez, Xavier Pinson, Kathleen Jarnouen, Marine Charpentier, Raphael Pineau, Laëtitia Lallement & Rémy Pedeux. (2022) Characterization of the Peri-Membrane Fluorescence Phenomenon Allowing the Detection of Urothelial Tumor Cells in Urine. Cancers 14:9, pages 2171.
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Janani Manochkumar, C. George Priya Doss, Thomas Efferth & Siva Ramamoorthy. (2022) Tumor preventive properties of selected marine pigments against colon and breast cancer. Algal Research 61, pages 102594.
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María Lourdes Mourelle, Carmen P. Gómez & José L. Legido. 2021. Recent Advances in Micro and Macroalgal Processing. Recent Advances in Micro and Macroalgal Processing 537 603 .
Fernanda Malhão, Ana Catarina Macedo, Carla Costa, Eduardo Rocha & Alice Abreu Ramos. (2021) Fucoxanthin Holds Potential to Become a Drug Adjuvant in Breast Cancer Treatment: Evidence from 2D and 3D Cell Cultures. Molecules 26:14, pages 4288.
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Masaru Terasaki, Atsuhito Kubota, Hiroyuki Kojima, Hayato Maeda, Kazuo Miyashita, Chikara Kawagoe, Michihiro Mutoh & Takuji Tanaka. (2021) Fucoxanthin and Colorectal Cancer Prevention. Cancers 13:10, pages 2379.
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Saikat Dewanjee, Sonjit Das, Swarnalata Joardar, Simanta Bhattacharjee & Pratik Chakraborty. 2021. Carotenoids: Structure and Function in the Human Body. Carotenoids: Structure and Function in the Human Body 475 512 .
Sarah Méresse, Mostefa Fodil, Fabrice Fleury & Benoît Chénais. (2020) Fucoxanthin, a Marine-Derived Carotenoid from Brown Seaweeds and Microalgae: A Promising Bioactive Compound for Cancer Therapy. International Journal of Molecular Sciences 21:23, pages 9273.
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Masaru Terasaki, Yasuhiro Kuramitsu, Mareshige Kojoma, Sang-Yong Kim, Takuji Tanaka, Hayato Maeda, Kazuo Miyashita, Chikara Kawagoe, Shoui Kohno & Michihiro Mutoh. (2020) High fucoxanthin wakame (Undaria pinnatifida) prevents tumor microenvironment formation in an AOM/DSS mouse carcinogenic model. Journal of Functional Foods 64, pages 103709.
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Masaru Terasaki, Mimori Ikuta, Hiroyuki Kojima, Takuji Tanaka, Hayato Maeda, Kazuo Miyashita & Michihiro Mutoh. (2019) Dietary Fucoxanthin Induces Anoikis in Colorectal Adenocarcinoma by Suppressing Integrin Signaling in a Murine Colorectal Cancer Model. Journal of Clinical Medicine 9:1, pages 90.
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Shuya Tamura, Takumi Narita, Gen Fujii, Shingo Miyamoto, Takahiro Hamoya, Yurie Kurokawa, Maiko Takahashi, Kouhei Miki, Yui Matsuzawa, Masami Komiya, Masaru Terasaki, Tomohiro Yano & Michihiro Mutoh. (2019) Inhibition of NF-kappaB transcriptional activity enhances fucoxanthinol-induced apoptosis in colorectal cancer cells. Genes and Environment 41:1.
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Masaru Terasaki, Tatsuya Iida, Fubuki Kikuchi, Kanae Tamura, Tetsuya Endo, Yasuhiro Kuramitsu, Takuji Tanaka, Hayato Maeda, Kazuo Miyashita & Michihiro Mutoh. (2019) Fucoxanthin potentiates anoikis in colon mucosa and prevents carcinogenesis in AOM/DSS model mice. The Journal of Nutritional Biochemistry 64, pages 198-205.
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Masaru Terasaki, Naoya Matsumoto, Ryuichi Hashimoto, Tetsuya Endo, Hayato Maeda, Junichi Hamada, Kazumi Osada, Kazuo Miyashita & Michihiro Mutoh. (2019) Fucoxanthin administration delays occurrence of tumors in xenograft mice by colonospheres, with an anti-tumor predictor of glycine. Journal of Clinical Biochemistry and Nutrition 64:1, pages 52-58.
Crossref
Bing Hu, Tong Zhang, Hong-Mei An, Jia-Lu Zheng, Xia Yan & Xiao-Wei Huang. (2018) Herbal formula YGJDSJ inhibits anchorage-independent growth and induces anoikis in hepatocellular carcinoma Bel-7402 cells. BMC Complementary and Alternative Medicine 18:1.
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