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Original Articles

Bixin Triggers Apoptosis of Human Hep3B Hepatocellular Carcinoma Cells: An Insight to Molecular and IN SILICO Approach

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Pages 971-983 | Received 21 Jul 2017, Accepted 04 Jun 2018, Published online: 11 Sep 2018

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Lia Kusmita, Yuvianti Dwi Franyoto, Mutmainah Mutmainah, Ika Puspitaningrum & Agustina D. R. Nurcahyanti. (2022) Bixa orellana L. carotenoids: antiproliferative activity on human lung cancer, breast cancer, and cervical cancer cells in vitro. Natural Product Research 36:24, pages 6421-6427.
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Kaviyapriya Muthusamy, Gnanam Ramasamy, Caroline Ravikumar, Senthil Natesan, Raveendran Muthurajan, Sivakumar Uthandi, Kumaran Kalyanasundaram & Vikas Tiwari. Exploring bixin from Bixa orellana L. seeds: quantification and in silico insights into its anti-cancer potential. Journal of Biomolecular Structure and Dynamics 0:0, pages 1-15.
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Articles from other publishers (19)

Yu-Qiong He, Can-Can Zhou, Sheng-Gui Jiang, Wen-Qian Lan, Feng Zhang, Xia Tao & Wan-Sheng Chen. (2024) Natural products for the treatment of chemotherapy-related cognitive impairment and prospects of nose-to-brain drug delivery. Frontiers in Pharmacology 15.
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Arghadip Das, Supravat Das, Sanchari Bhattacharya, Debjeet Sur, Samrat Bose & Tilottama Mukherjee. (2023) Potential Oncotherapeutic Effects of Nutraceuticals against Hepatocellular Carcinoma: Recent Advancements. Current Functional Foods 1:2.
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Asma Ashraf, Muhammad Umar Ijaz, Saima Muzammil, Muhammad Muzammil Nazir, Saima Zafar, S.M. Neamul Kabir Zihad, Shaikh Jamal Uddin, Md Saquib Hasnain & Amit Kumar Nayak. (2023) The role of bixin as antioxidant, anti-inflammatory, anticancer, and skin protecting natural product extracted from Bixa orellana L. Fitoterapia 169, pages 105612.
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Ayesheh Enayati, Atefe Rezaei, Seid Reza Falsafi, Hadis Rostamabadi, Narjes Malekjani, Sahar Akhavan-Mahdavi, Mohammad Saeed Kharazmi & Seid Mahdi Jafari. (2023) Bixin-loaded colloidal nanodelivery systems, techniques and applications. Food Chemistry 412, pages 135479.
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Shailaja Amol Dombe & Pramodkumar Jaykumar Shirote. (2023) Phytonutraceuticals in Cancer Prevention and Therapeutics. Current Nutrition & Food Science 19:3, pages 209-228.
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Senthil Kumar Raju, Sabarainath Chandrasekar, Priyadharshini Vengadhajalapathy, Revathy Sundaram, Sangeetha Periyasamyy, Thatchayani Chinnaraj, Praveen Sekar & Shridharshini Kumar. (2023) Review on phytochemical composition and pharmacological activities of Bixa orellana. Journal of Pharmaceutical and Biological Sciences 10:2, pages 57-67.
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Ayesheh Enayati, Elham Assadpour & Seid Mahdi Jafari. 2023. Handbook of Food Bioactive Ingredients. Handbook of Food Bioactive Ingredients 757 789 .
Ayesheh Enayati, Elham Assadpour & Seid Mahdi Jafari. 2022. Handbook of Food Bioactive Ingredients. Handbook of Food Bioactive Ingredients 1 33 .
Ana Paula da Fonseca Machado, Mariana da Rocha Alves, Roberto de Paula do Nascimento, Lívia Mateus Reguengo & Mario Roberto Marostica Junior. (2022) Antiproliferative effects and main molecular mechanisms of Brazilian native fruits and their by-products on lung cancer. Food Research International 162, pages 111953.
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Saikat Mitra, Talha Bin Emran, Deepak Chandran, B. M. Redwan Matin Zidan, Rajib Das, Sukamto S. Mamada, Ayu Masyita, Mirnawati Salampe, Firzan Nainu, Mayeen Uddin Khandaker, Abubakr M. Idris & Jesus Simal-Gandara. (2022) Cruciferous vegetables as a treasure of functional foods bioactive compounds: Targeting p53 family in gastrointestinal tract and associated cancers. Frontiers in Nutrition 9.
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Hwa Seung Han, Song Yi Koo & Ki Young Choi. (2022) Emerging nanoformulation strategies for phytocompounds and applications from drug delivery to phototherapy to imaging. Bioactive Materials 14, pages 182-205.
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Alexsandro Tavares Figueiredo-Junior, Samuel Santos Valença, Priscilla Vanessa Finotelli, Francisca de Fátima dos Anjos, Lycia de Brito-Gitirana, Christina Maeda Takiya & Manuella Lanzetti. (2022) Treatment with Bixin-Loaded Polymeric Nanoparticles Prevents Cigarette Smoke-Induced Acute Lung Inflammation and Oxidative Stress in Mice. Antioxidants 11:7, pages 1293.
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Yunfeng Qiu, Changfeng Li & Bin Zhang. (2022) Bixin Prevents Colorectal Cancer Development through AMPK-Activated Endoplasmic Reticulum Stress. BioMed Research International 2022, pages 1-12.
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Zhong‐Ji Qian, Mei‐Fang Chen, Jiali Chen, Yi Zhang, Chunxia Zhou, Pengzhi Hong & Ping Yang. (2021) Intracellular ethanol‐mediated oxidation and apoptosis in HepG2/CYP2E1 cells impaired by two active peptides from seahorse ( Hippocampus kuda bleeler) protein hydrolysates via the Nrf2/HO‐1 and akt pathways . Food Science & Nutrition 9:3, pages 1584-1602.
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Alexsandro Tavares Figueiredo-Junior, Francisca de Fátima dos Anjos, Francisco das Chagas de Melo Brito, Vicente Galber Freitas Viana, Samuel Santos Valença, Manuella Lanzetti & Priscilla Vanessa Finotelli. (2020) Bixin loaded on polymeric nanoparticles: synthesis, characterization, and antioxidant applications in a biological system. Applied Nanoscience 11:1, pages 63-78.
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Saikat Dewanjee, Sonjit Das, Swarnalata Joardar, Simanta Bhattacharjee & Pratik Chakraborty. 2021. Carotenoids: Structure and Function in the Human Body. Carotenoids: Structure and Function in the Human Body 475 512 .
Ye Yu, Dong-Ming Wu, Jing Li, Shi-Hua Deng, Teng Liu, Ting Zhang, Miao He, Yang-Yang Zhao & Ying Xu. (2020) Bixin Attenuates Experimental Autoimmune Encephalomyelitis by Suppressing TXNIP/NLRP3 Inflammasome Activity and Activating NRF2 Signaling. Frontiers in Immunology 11.
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Lenka Koklesova, Alena Liskova, Marek Samec, Constanze Buhrmann, Samson Mathews Samuel, Elizabeth Varghese, Milad Ashrafizadeh, Masoud Najafi, Mehdi Shakibaei, Dietrich Büsselberg, Frank A. Giordano, Olga Golubnitschaja & Peter Kubatka. (2020) Carotenoids in Cancer Apoptosis—The Road from Bench to Bedside and Back. Cancers 12:9, pages 2425.
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Juan Carlos Castro, Joseph Dylan Maddox, Marianela Cobos, Jae Diana Paredes, Anthony Jhoao Fasabi, Gabriel Vargas-Arana, Jorge Luis Marapara, Pedro Marcelino Adrianzen, María Zadith Casuso & Segundo Levi Estela. 2019. Pharmacognosy - Medicinal Plants. Pharmacognosy - Medicinal Plants.

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