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Vitamin B6 kills hepatoma cells in culture

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Pages 216-222 | Published online: 04 Aug 2009

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Dai SHIMADA, Ayumi FUKUDA, Hiroaki KANOUCHI, Mitsuharu MATSUMOTO & Tatsuzo OKA. (2006) Vitamin B6 Suppresses Growth of the Feline Mammary Tumor Cell Line FRM. Bioscience, Biotechnology, and Biochemistry 70:4, pages 1038-1040.
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Dai Shimada, Ayumi Fukuda, Hiroaki Kawaguchi, Norihisa Kato, Hiroki Yoshida, Hiroaki Kanouchi & Tatsuzo Oka. (2005) Effect of High Dose of Pyridoxine on Mammary Tumorigenesis. Nutrition and Cancer 53:2, pages 202-207.
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Ana Molina, Tatsuzo Oka, SaturninoM. Muñoz, Mika Chikamori‐Aoyama, Masashi Kuwahata & Yasuo Natori. (1997) Vitamin B6 suppresses growth and expression of albumin gene in a human hepatoma cell line HepG2. Nutrition and Cancer 28:2, pages 206-211.
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KarlJ. Gebhard, DailaS. Gridley, DwightR. Stickney & TerryD. Shulz. (1990) Enhancement of immune status by high levels of dietary vitamin B‐6 without growth inhibition of human malignant melanoma in athymic nude mice. Nutrition and Cancer 14:1, pages 15-26.
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DennisM. DiSorbo, Richard Wagner$suffix/text()$suffix/text() & Larry Nathanson. (1985) In vivo and in vitro inhibition of B16 melanoma growth by vitamin b6 . Nutrition and Cancer 7:1-2, pages 43-52.
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DennisM. DiSorbo & Larry Nathanson. (1983) High‐dose pyridoxal supplemented culture medium inhibits the growth of a human malignant melanoma cell line. Nutrition and Cancer 5:1, pages 10-15.
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Tilahun Ayane Debele, Chi-Kang Chen, Lu-Yi Yu & Chun-Liang Lo. (2023) Lipopolyplex-Mediated Co-Delivery of Doxorubicin and FAK siRNA to Enhance Therapeutic Efficiency of Treating Colorectal Cancer. Pharmaceutics 15:2, pages 596.
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Gerald Litwack. 2022. Human Biochemistry. Human Biochemistry 703 747 .
Michael N. Viegas, Vincent Laizé, Maria A. Salgado, Carla Aguiar & Jorge Dias. (2019) Effect of Trace Minerals and B Vitamins on the Proliferation/Cytotoxicity and Mineralization of a Gilthead Seabream Bone–Derived Cell Line. Biological Trace Element Research 196:2, pages 629-638.
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L Galluzzi, E Vacchelli, J Michels, P Garcia, O Kepp, L Senovilla, I Vitale & G Kroemer. (2013) Effects of vitamin B6 metabolism on oncogenesis, tumor progression and therapeutic responses. Oncogene 32:42, pages 4995-5004.
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Galina Lurie, Lynne R. Wilkens, Yurii B. Shvetsov, Nicholas J. Ollberding, Adrian A. Franke, Brian E. Henderson, Laurence N. Kolonel & Marc T. Goodman. (2012) Prediagnostic Plasma Pyridoxal 5′-Phosphate (Vitamin B6) Levels and Invasive Breast Carcinoma Risk: The Multiethnic Cohort. Cancer Epidemiology, Biomarkers & Prevention 21:11, pages 1942-1948.
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Sang Woon Choi & Simonetta Friso. 2012. Water Soluble Vitamins. Water Soluble Vitamins 247 264 .
Sangita Manna, M. Janarthan, Balaram Ghosh, Basabi Rana, Ajay Rana & Malay Chatterjee. (2010) Fish oil regulates cell proliferation, protect DNA damages and decrease HER-2/neu and c-Myc protein expression in rat mammary carcinogenesis. Clinical Nutrition 29:4, pages 531-537.
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Paula Lumy Takeuchi, Lusânia Maria Greggi Antunes & Catarina Satie Takahashi. (2007) Evaluation of the clastogenicity and anticlastogenicity of vitamin B6 in human lymphocyte cultures. Toxicology in Vitro 21:4, pages 665-670.
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John Kauh & Jay Umbreit. (2004) Colorectal cancer prevention. Current Problems in Cancer 28:5, pages 240-264.
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Yoshiyuki Mizushina, Xianai Xu, Kiminori Matsubara, Chikako Murakami, Isoko Kuriyama, Masahiko Oshige, Masaharu Takemura, Norihisa Kato, Hiromi Yoshida & Kengo Sakaguchi. (2003) Pyridoxal 5′-phosphate is a selective inhibitor in vivo of DNA polymerase α and ε. Biochemical and Biophysical Research Communications 312:4, pages 1025-1032.
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Kiminori Matsubara, Shun-ichiro Komatsu, Tatsuzo Oka & Norihisa Kato. (2003) Vitamin B6-mediated suppression of colon tumorigenesis, cell proliferation, and angiogenesis (review). The Journal of Nutritional Biochemistry 14:5, pages 246-250.
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David C. Plais, James Gardner-Thorpe, Hiromichi Ito, Stanley W. Ashley & Edward E. Whang. (2003) Vitamin B6 inhibits the growth of human pancreatic carcinoma. Nutrition Research 23:5, pages 673-679.
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S. Komatsu, N. Yanaka, K. Matsubara & N. Kato. (2003) Antitumor effect of vitamin B6 and its mechanisms. Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics 1647:1-2, pages 127-130.
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T. Oka. (2009) Modulation of gene expression by vitamin B6. Nutrition Research Reviews 14:02, pages 257.
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Shun-ichiro Komatsu, Norihisa Kato, Hiromitsu Watanabe, Tatsuzo Oka, Haruhito Tsuge & Hironori Nii. (2001) Vitamin B-6–Supplemented Diets Compared with a Low Vitamin B-6 Diet Suppress Azoxymethane-Induced Colon Tumorigenesis in Mice by Reducing Cell Proliferation. The Journal of Nutrition 131:8, pages 2204-2207.
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JOHN W. THANASSI & NATALIE T. MEISLER. (2006) Metabolism of Pyridoxine in Hepatomas. Annals of the New York Academy of Sciences 585:1, pages 424-437.
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Terry D. Shultz, Doris Lee, Dwight R. Stickney & Daila S. Gridley. (1989) Effect of pyridoxine and pyridoxal on the in vitro growth of human and murine cancer cells. Nutrition Research 9:2, pages 133-151.
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Robert D. Reynolds. 1987. Essential Nutrients in Carcinogenesis. Essential Nutrients in Carcinogenesis 339 347 .
Raymond J. ShambergerRaymond J. Shamberger. 1984. Nutrition and Cancer. Nutrition and Cancer 117 194 .

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