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A fish oil diet inhibits colon cancer in mice

Pages 1-11 | Received 11 Apr 1990, Accepted 05 Sep 1990, Published online: 04 Aug 2009

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Ralf Schubert, Janine Reichenbach, Claudia Koch, Stephan Kloeß, Ulrike Koehl, Klaus Mueller, Patrick Baer, Christopher Beermann, Hansjosef Boehles & Stefan Zielen. (2010) Reactive Oxygen Species Abrogate the Anticarcinogenic Effect of Eicosapentaenoic Acid in Atm-Deficient Mice. Nutrition and Cancer 62:5, pages 584-592.
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Christopher M. Somers, Jacek M. Kwiecien & James S. Quinn. (2005) A marine fish diet reduces spontaneous lymphoma in outbred Swiss-Webster mice. Leukemia & Lymphoma 46:12, pages 1797-1800.
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Naoyuki Danbara, Takashi Yuri, Miki Tsujita-Kyutoku, Mutsuya Sato, Hideto Senzaki, Hideho Takada, Takahiko Hada, Teruo Miyazawa, Kazuichi Okazaki & Airo Tsubura. (2004) Conjugated Docosahexaenoic Acid Is a Potent Inducer of Cell Cycle Arrest and Apoptosis and Inhibits Growth of Colo 201 Human Colon Cancer Cells. Nutrition and Cancer 50:1, pages 71-79.
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Dong‐Yeon Kim, Kyeong‐Hee Chung & Jung‐Hee Lee. (1998) Stimulatory effects of high‐fat diets on colon cell proliferation depend on the type of dietary fat and site of the colon. Nutrition and Cancer 30:2, pages 118-123.
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PeterJ. Horvath, HibaH. Shuhaiber, CarolS. Fink & AtifB. Awad. (1997) Type of dietary fiber, not fat, alters phospholipase D and ornithine decarboxylase activities in the rat large intestine. Nutrition and Cancer 27:2, pages 143-149.
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Hans‐Peter Bartram, Andrea Gostner, Elisabeth Kelber, Gerda Dusel, Antje Weimer, Wolfgang Scheppach & Heinrich Kasper. (1996) Effects of fish oil on fecal bacterial enzymes and steroid excretion in healthy volunteers: Implications for colon cancer prevention. Nutrition and Cancer 25:1, pages 71-78.
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Dong‐YeonK. Lee, RobertS. Chapkin & JoanneR. Lupton. (1993) Dietary fat and fiber modulate colonic cell proliferation in an interactive site‐specific manner. Nutrition and Cancer 20:2, pages 107-118.
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Articles from other publishers (48)

Alireza Tojjari, Khalil Choucair, Arezoo Sadeghipour, Azhar Saeed & Anwaar Saeed. (2023) Anti-Inflammatory and Immune Properties of Polyunsaturated Fatty Acids (PUFAs) and Their Impact on Colorectal Cancer (CRC) Prevention and Treatment. Cancers 15:17, pages 4294.
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Carlotta Franchi, Ilaria Ardoino, Cristina Bosetti, Eva Negri, Diego Serraino, Anna Crispo, Attilio Giacosa, Elena Fattore, Alberto Dolci, Francesca Bravi, Federica Turati, Carlo La Vecchia & Barbara D’Avanzo. (2022) Inverse Association between Canned Fish Consumption and Colorectal Cancer Risk: Analysis of Two Large Case–Control Studies. Nutrients 14:8, pages 1663.
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Mayu Sebe, Rie Tsutsumi, Sotaro Yamaguchi, Yousuke T. Horikawa, Nagakatsu Harada, Takuro Oyama, Nami Kakuta, Katsuya Tanaka, Yasuo M. Tsutsumi, Yutaka Nakaya & Hiroshi Sakaue. (2016) The synergystic effects of omega-3 fatty acids against 5-fluorouracil-induced mucosal impairment in mice. BMC Nutrition 2:1.
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Subreen A. Khatib, Emily L. Rossi, Laura W. Bowers & Stephen D. Hursting. (2016) Reducing the burden of obesity-associated cancers with anti-inflammatory long-chain omega-3 polyunsaturated fatty acids. Prostaglandins & Other Lipid Mediators 125, pages 100-107.
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João Pedro de Magalhães, Michael Müller, G. Ed. Rainger & Wilma Steegenga. (2016) Fish oil supplements, longevity and aging. Aging 8:8, pages 1578-1582.
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Amikar Sehdev & Bert H. O’Neil. (2015) The Role of Aspirin, Vitamin D, Exercise, Diet, Statins, and Metformin in the Prevention and Treatment of Colorectal Cancer. Current Treatment Options in Oncology 16:9.
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Hannah Arem, Marian L. Neuhouser, Melinda L. Irwin, Brenda Cartmel, Lingeng Lu, Harvey Risch, Susan T. Mayne & Herbert Yu. (2012) Omega-3 and omega-6 fatty acid intakes and endometrial cancer risk in a population-based case–control study. European Journal of Nutrition 52:3, pages 1251-1260.
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Michael McCulloch, Michael Broffman, Mark van der Laan, Alan Hubbard, Lawrence Kushi, Donald I. Abrams, Jin Gao & John M. ColfordJrJr. (2011) Colon Cancer Survival With Herbal Medicine and Vitamins Combined With Standard Therapy in a Whole-Systems Approach. Integrative Cancer Therapies 10:3, pages 240-259.
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Joo Y Lee, Ling Zhao & Daniel H Hwang. (2010) Modulation of pattern recognition receptor-mediated inflammation and risk of chronic diseases by dietary fatty acids. Nutrition Reviews 68:1, pages 38-61.
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Simona Serini, Elisabetta Piccioni & Gabriella Calviello. 2010. Dietary Omega-3 Polyunsaturated Fatty Acids and Cancer. Dietary Omega-3 Polyunsaturated Fatty Acids and Cancer 67 89 .
Yuko Yonezawa, Hiromi Yoshida & Yoshiyuki Mizushina. (2007) Mechanism of Growth Inhibition of Human Cancer Cells by Conjugated Eicosapentaenoic Acid, an Inhibitor of DNA Polymerase and Topoisomerase. International Journal of Molecular Sciences 8:12, pages 1206-1224.
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Carsten N. Gutt, Lars Brinkmann, Arianeb Mehrabi, Hamidreza Fonouni, Beat P. Müller-Stich, Gregor Vetter, Jürgen M. Stein, Peter Schemmer & Markus W. Büchler. (2007) Dietary omega-3-polyunsaturated fatty acids prevent the development of metastases of colon carcinoma in rat liver. European Journal of Nutrition 46:5, pages 279-285.
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Sang Lee, Kathleen M. Gura, Sendia Kim, Danielle A. Arsenault, Bruce R. Bistrian & Mark Puder. (2006) Current Clinical Applications of Ω‐6 and Ω‐3 Fatty Acids. Nutrition in Clinical Practice 21:4, pages 323-341.
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DAVID HEBER & SUSAN BOWERMAN. 2006. Nutritional Oncology. Nutritional Oncology 1 13 .
W Elaine Hardman, LuZhe Sun, Nicholas Short & Ivan L Cameron. (2005) Dietary omega-3 fatty acids and ionizing irradiation on human breast cancer xenograft growth and angiogenesis. Cancer Cell International 5:1.
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Yuko Yonezawa, Takahiko Hada, Keisuke Uryu, Tsuyoshi Tsuzuki, Takahiro Eitsuka, Teruo Miyazawa, Chikako Murakami-Nakai, Hiromi Yoshida & Yoshiyuki Mizushina. (2005) Inhibitory effect of conjugated eicosapentaenoic acid on mammalian DNA polymerase and topoisomerase activities and human cancer cell proliferation. Biochemical Pharmacology 70:3, pages 453-460.
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Guo-Dong Zhou, Natasa Popovic, Joanne R. Lupton, Nancy D. Turner, Robert S. Chapkin & Kirby C. Donnelly. (2005) Tissue-Specific Attenuation of Endogenous DNA I-Compounds in Rats by Carcinogen Azoxymethane: Possible Role of Dietary Fish Oil in Colon Cancer Prevention. Cancer Epidemiology, Biomarkers & Prevention 14:5, pages 1230-1235.
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Adriana B. Actis, David C. Cremonezzi, Irena B. King, Silvia Joekes, Aldo R. Eynard & Mirta A. Valentich. (2005) Effects of soy oil on murine salivary tumorigenesis. Prostaglandins, Leukotrienes and Essential Fatty Acids 72:3, pages 187-194.
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Susanna C Larsson, Maria Kumlin, Magnus Ingelman-Sundberg & Alicja Wolk. (2004) Dietary long-chain n−3 fatty acids for the prevention of cancer: a review of potential mechanisms. The American Journal of Clinical Nutrition 79:6, pages 935-945.
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Catherine E Roynette, Philip C Calder, Yves M Dupertuis & Claude Pichard. (2004) n-3 Polyunsaturated fatty acids and colon cancer prevention. Clinical Nutrition 23:2, pages 139-151.
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C. Rupnarain, Z. Dlamini, S. Naicker & K. Bhoola. (2004) Colon cancer: genomics and apoptotic events. Biological Chemistry 385:6.
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Jean-Louis Nano, Christine Nobili, Fernand Girard-Pipau & Patrick Rampal. (2003) Effects of fatty acids on the growth of Caco-2 cells. Prostaglandins, Leukotrienes and Essential Fatty Acids 69:4, pages 207-215.
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W. Elaine Hardman. (2002) Omega-3 Fatty Acids to Augment Cancer Therapy. The Journal of Nutrition 132:11, pages 3508S-3512S.
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Leana J. Coleman, Eva K. Landström, Peter J. Royle, Anthony R. Bird & Graeme H. McIntosh. (2002) A Diet Containing α-Cellulose and Fish Oil Reduces Aberrant Crypt Foci Formation and Modulates Other Possible Markers for Colon Cancer Risk in Azoxymethane-Treated Rats. The Journal of Nutrition 132:8, pages 2312-2318.
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Michael McEntee & Jay Whelan. 2001. Nutrient-Gene Interactions in Health and Disease. Nutrient-Gene Interactions in Health and Disease 231 260 .
Z.-Y. Chen & N.W. Istfan. (2001) Docosahexaenoic acid, a major constituent of fish oil diets, prevents activation of cyclin-dependent kinases and S-phase entry by serum stimulation in HT-29 cells. Prostaglandins, Leukotrienes and Essential Fatty Acids (PLEFA) 64:1, pages 67-73.
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M. Kontogiannea, A. Gupta, F. Ntanios, T. Graham, P. Jones & S. Meterissian. (2000) ω-3 Fatty Acids Decrease Endothelial Adhesion of Human Colorectal Carcinoma Cells. Journal of Surgical Research 92:2, pages 201-205.
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Melissa B. Hansen Petrik, Chun-Hung Chiu, Michael F. McEntee & Jay Whelan. (2000) Antagonism of Arachidonic Acid Is Linked to the Antitumorigenic Effect of Dietary Eicosapentaenoic Acid in ApcMin/+ Mice. The Journal of Nutrition 130:5, pages 1153-1158.
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R.A. Silva, S.E. Muñoz, C.A. Perez & A.R. Eynard. (2000) Effects of dietary fat on benz-a-pyrene-induced forestomach tumorigenesis in mice chronically exposed to arsenic. Experimental and Toxicologic Pathology 52:1, pages 11-16.
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Daniel P. Gaposchkin, Raphael A. Zoeller & Selwyn A. Broitman. (2000) Incorporation of polyunsaturated fatty acids into CT-26, a transplantable murine colonic adenocarcinoma. Lipids 35:2, pages 181-186.
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Rosemary G. Clarke, Elizabeth K. Lund, Peter Latham, Andrew C. Pinder & Ian T. Johnson. (1999) Effect of eicosapentaenoic acid on the proliferation and incidence of apoptosis in the colorectal cell line HT29. Lipids 34:12, pages 1287-1295.
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Masazumi Takeshita, Hiroshi Ueda, Komei Shirabe, Yasunori Higuchi & Satoshi Yoshida. (1997) Lack of promotion of colon carcinogenesis by high-oleic safflower oil. Cancer 79:8, pages 1487-1493.
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Qingyong Ma, Margaret Hoper, Isla Halliday & Brian J Rowlands. (1996) Diet and experimental colorectal cancer. Nutrition Research 16:3, pages 413-426.
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C J Van Noorden. (1995) Effects of n-3 and n-6 polyunsaturated fatty acid-enriched diets on lipid metabolism in periportal and pericentral compartments of female rat liver lobules and the consequences for cell proliferation after partial hepatectomy.. Journal of Lipid Research 36:8, pages 1708-1720.
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