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Studies of immunomodulating actions of carotenoids. II. astaxanthin enhances in vitro antibody production to T‐dependent antigens without facilitating polyclonal B‐cell activation

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Pages 269-280 | Received 16 Jun 1992, Accepted 02 Dec 1992, Published online: 04 Aug 2009

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Weihong Sun, Hong Lin, Yuxiu Zhai, Limin Cao, Kailiang Leng & Lihong Xing. (2015) Separation, Purification, and Identification of (3S,3′S)-trans-Astaxanthin from Haematococcus pluvialis. Separation Science and Technology 50:9, pages 1377-1383.
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R. Raja, S. Hemaiswarya, N. Ashok Kumar, S. Sridhar & R. Rengasamy. (2008) A Perspective on the Biotechnological Potential of Microalgae. Critical Reviews in Microbiology 34:2, pages 77-88.
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Harumi Jyonouchi, Sining Sun, Koji Iijima & Myron D. Gross. (2000) Antitumor Activity of Astaxanthin and Its Mode of Action. Nutrition and Cancer 36:1, pages 59-65.
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Jean Soon Park, Boon P. Chew, Teri S. Wong, Ji-Xiang Zhang & Nancy S. Magnuson. (1999) Dietary Lutein But Not Astaxanthin or β-Carotene Increases pim-1 Gene Expression in Murine Lymphocytes. Nutrition and Cancer 33:2, pages 206-212.
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Harumi Jyonouchim, Sining Sun & Yoshifumi Tomita. (1996) Actions of β-Carotene on T-Helper Cell Functions for Antibody Production. Journal of Nutritional Immunology 3:4, pages 21-34.
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Harumi Jyonouchi, Sining Sun, Munetaka Mizokami & MyronD. Gross. (1996) Effects of various carotenoids on cloned, effector‐stage T‐helper cell activity. Nutrition and Cancer 26:3, pages 313-324.
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Harumi Jyonouchi, Lei Zhang, Myron Gross & Yoshifumi Tomita. (1994) Immunomodulating actions of carotenoids: Enhancement of in vivo and in vitro antibody production to T‐dependent antigens. Nutrition and Cancer 21:1, pages 47-58.
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Pinar Buket Demirel & Bilge Guvenc Tuna. 2021. Global Perspectives on Astaxanthin. Global Perspectives on Astaxanthin 427 445 .
Keng Chin Lim, Fatimah Md. Yusoff, Mohamed Shariff, Mohd. Salleh Kamarudin & Norio Nagao. (2019) Dietary supplementation of astaxanthin enhances hemato-biochemistry and innate immunity of Asian seabass, Lates calcarifer (Bloch, 1790). Aquaculture 512, pages 734339.
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Sergio Davinelli, Michael Nielsen & Giovanni Scapagnini. (2018) Astaxanthin in Skin Health, Repair, and Disease: A Comprehensive Review. Nutrients 10:4, pages 522.
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Ahmad Mohammad Abdel-Mawgoud & Gregory Stephanopoulos. (2018) Simple glycolipids of microbes: Chemistry, biological activity and metabolic engineering. Synthetic and Systems Biotechnology 3:1, pages 3-19.
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Weihong Sun, Lihong Xing, Hong Lin, Kailiang Leng, Yuxiu Zhai & Xiaofang Liu. (2016) Assessment and comparison of in vitro immunoregulatory activity of three astaxanthin stereoisomers. Journal of Ocean University of China 15:2, pages 283-287.
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Min Chang Son, Dong-Jun Lee, Sejin Park, Min Sung Kim, Chul Won Lee & Won Gun An. (2015) Development of Axenic Culture and Astaxanthin Production in Microalgae. Journal of Life Science 25:7, pages 733-739.
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Jin Liu, Zheng Sun, Henri Gerken, Zheng Liu, Yue Jiang & Feng Chen. (2014) Chlorella zofingiensis as an Alternative Microalgal Producer of Astaxanthin: Biology and Industrial Potential. Marine Drugs 12:6, pages 3487-3515.
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Chang Hwan Yoon, Hee Sung Bok, Dae Ki Choi & Kyung Ho Row. (2012) Optimization Condition of Astaxanthin Extract from Shrimp Waste Using Response Surface Methodology. Korean Chemical Engineering Research 50:3, pages 545-550.
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Chang Xu, Hui Wang, Yu Huan Liu, Prof. Roger Ruan & Yun Li. (2012) Research on Edible Fungi and Algae as Feed Supplement. Advanced Materials Research 518-523, pages 608-613.
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Preejith Vachali, Prakash Bhosale & Paul S. Bernstein. 2012. Microbial Carotenoids From Fungi. Microbial Carotenoids From Fungi 41 59 .
Tae-Won Kwak, Ji-Young Cha, Chul-Won Lee, Young-Min Kim, Byung-Hong Yoo, Sung-Gu Kim, Jong-Myoung Kim, Seong-Ha Park & Won-Gun An. (2011) Anti-Inflammatory and Antioxidant Effect of Astaxanthin Derived from Microalgae. Journal of Life Science 21:10, pages 1377-1384.
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Jean Soon Park, Jong Hee Chyun, Yoo Kyung Kim, Larry L Line & Boon P Chew. (2010) Astaxanthin decreased oxidative stress and inflammation and enhanced immune response in humans. Nutrition & Metabolism 7:1.
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Rosemari Otton, Douglas Popp Marin, Anaysa Paola Bolin, Rita de Cássia Macedo dos Santos, Tatiana Geraldo Polotow, Sandra Coccuzzo Sampaio & Marcelo Paes de Barros. (2010) Astaxanthin ameliorates the redox imbalance in lymphocytes of experimental diabetic rats. Chemico-Biological Interactions 186:3, pages 306-315.
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Mariana Ferreira Leite, Amanda Martins de Lima, Monica Miyuki Massuyama & Rosemari Otton. (2010) Astaxanthin restores the enzymatic antioxidant profile in salivary gland of alloxan-induced diabetic rats. Archives of Oral Biology 55:7, pages 479-485.
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Paola Palozza, Cristiana Torelli, Alma Boninsegna, Rossella Simone, Assunta Catalano, Maria Cristina Mele & Nevio Picci. (2009) Growth-inhibitory effects of the astaxanthin-rich alga Haematococcus pluvialis in human colon cancer cells. Cancer Letters 283:1, pages 108-117.
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Naoko TAKAHASHI, Toshihiro NADE, Yoko HAMASAKI, Keigo KUCHIDA & Nobuhiro KIMURA. (2009) Relationship between presence and absence of SHIKORI beef checked by the grading examination or the cutting examination and the blood property in Holstein fatting steers at shipping. Nihon Chikusan Gakkaiho 80:3, pages 341-348.
Crossref
. (2008) Effect of Dietary Combined Probiotics(Any-Lac, ®) Supplementation Contained with Phaffia rhodozyma on the Growth Performances and Meat Quality of Pigs. Journal of Animal Science and Technology 50:5, pages 657-666.
Crossref
Hiroshige ITAKURA, Jiro TAKAHASHIAkitoshi KITAMURA. (2008) Astaxanthin for Complementary and Alternative Medicine補完代替医療素材としてのアスタキサンチン. Japanese Journal of Complementary and Alternative Medicine 5:3, pages 173-182.
Crossref
Hyun-Seok Youn, Myong-Kyun Roh, Andreas Weber, Gordon T. Wilkinson & Byung-Soo Chun. (2007) Solubility of astaxanthin in supercritical carbon dioxide. Korean Journal of Chemical Engineering 24:5, pages 831-834.
Crossref
Shokufeh Golkhoo, Fatemeh Barantalab, Ali Reza Ahmad & Zuhair Muhammad H. (2007) Purification of Astaxanthin from Mutant of Phaffia rhodozyma JH-82 Which Isolated from Forests Trees of Iran. Pakistan Journal of Biological Sciences 10:5, pages 802-805.
Crossref
Mohamed M. Rafi, Prem Narayan Yadav & Marynell Reyes. (2007) Lycopene Inhibits LPS‐Induced Proinflammatory Mediator Inducible Nitric Oxide Synthase in Mouse Macrophage Cells. Journal of Food Science 72:1.
Crossref
Zhong-Ce Hu, Yu-Guo Zheng, Zhao Wang & Yin-Chu Shen. (2006) pH control strategy in astaxanthin fermentation bioprocess by Xanthophyllomyces dendrorhous. Enzyme and Microbial Technology 39:4, pages 586-590.
Crossref
Y.-G. Zheng, Z.-C. Hu, Z. Wang & Y.-C. Shen. (2006) Large-Scale Production of Astaxanthin by Xanthophyllomyces Dendrorhous. Food and Bioproducts Processing 84:2, pages 164-166.
Crossref
Laura M. Hix, Dean A. Frey, Mark D. McLaws, Marianne Østerlie, Samuel F. Lockwood & John S. Bertram. (2005) Inhibition of chemically-induced neoplastic transformation by a novel tetrasodium diphosphate astaxanthin derivative. Carcinogenesis 26:9, pages 1634-1641.
Crossref
Zhong-Ce Hu, Yu-Guo Zheng, Zhao Wang & Yin-Chu Shen. (2005) Effect of sugar-feeding strategies on astaxanthin production by Xanthophyllomyces dendrorhous. World Journal of Microbiology and Biotechnology 21:5, pages 771-775.
Crossref
Ching HouYomi Watanabe, Yuji Shimada & Toshihiro Nagao. 2005. Handbook of Industrial Biocatalysis. Handbook of Industrial Biocatalysis 8-1 8-27 .
Oi-Ming Lai & Casimir AkohYuji Shimada. 2005. Healthful Lipids. Healthful Lipids.
John Dore. 2004. Phytopharmaceuticals in Cancer Chemoprevention. Phytopharmaceuticals in Cancer Chemoprevention.
Martin Guerin, Mark E Huntley & Miguel Olaizola. (2003) Haematococcus astaxanthin: applications for human health and nutrition. Trends in Biotechnology 21:5, pages 210-216.
Crossref
. (2002) Effect of Egg Yolks from Laying Hens Intubated Astaxanthin on the Oxidation of Liver Microsome of Mouse. Journal of the Korean Society of Food Science and Nutrition 31:1, pages 155-159.
Crossref
. (2002) Changes of Lectin Activity of Kidney Beans by floating and Fermentation. Journal of the Korean Society of Food Science and Nutrition 31:1, pages 1-6.
Crossref
Kristina Meissner, Werner Siems, Olaf Sommerburg & Micheal Leichsenring. 2001. Handbook of Antioxidants. Handbook of Antioxidants.
Liu Beihui & Lee Yuan Kun. (2001) In vitro biosynthesis of xanthophylls by cell extractsof a green alga Chlorococcum. Plant Physiology and Biochemistry 39:2, pages 147-154.
Crossref
Hong Wook Kim, Boon P Chew, Teri S Wong, Jean Soon Park, Brian B.C Weng, Katherine M Byrne, Michael G Hayek & Gregory A Reinhart. (2000) Modulation of humoral and cell-mediated immune responses by dietary lutein in cats. Veterinary Immunology and Immunopathology 73:3-4, pages 331-341.
Crossref
Harold Schmitz & Kati Chevaux. 2000. Nutrition and Immunology. Nutrition and Immunology 107 119 .
Michelle S Santos, J Michael Gaziano, Lynette S Leka, Alison A Beharka, Charles H Hennekens & Simin Nikbin Meydani. (1998) β-Carotene–induced enhancement of natural killer cell activity in elderly men: an investigation of the role of cytokines. The American Journal of Clinical Nutrition 68:1, pages 164-170.
Crossref
Akihiro Yokoyama, Yoshikazu Shizuri & Norihiko Misawa. (1998) Production of new carotenoids, astaxanthin glucosides, by Escherichia coli transformants carrying carotenoid biosynthesis genes. Tetrahedron Letters 39:22, pages 3709-3712.
Crossref
Paul D. Fraser, Yutaka Miura & Norihiko Misawa. (1997) In Vitro Characterization of Astaxanthin Biosynthetic Enzymes. Journal of Biological Chemistry 272:10, pages 6128-6135.
Crossref
R. Walker. (1996) Modulation of toxicity by dietary and environmental factors. Environmental Toxicology and Pharmacology 2:2-3, pages 181-188.
Crossref
Ranald B. Cope, Meira Bosnic, Christa Boehm-Wilcox, Detlef Mohr & Vivienne E. Reeve. (1996) Dietary Butter Protects against Ultraviolet Radiation-Induced Suppression of Contact Hypersensitivity in Skh:HR-1 Hairless Mice. The Journal of Nutrition 126:3, pages 681-692.
Crossref
Nobuyoshi ShimidzuMasafumi GotoWataru Miki. (1996) Carotenoids as Singlet Oxygen Quenchers in Marine Organisms. Fisheries science 62:1, pages 134-137.
Crossref
SN Meydani, D Wu, MS Santos & MG Hayek. (1995) Antioxidants and immune response in aged persons: overview of present evidence. The American Journal of Clinical Nutrition 62:6, pages 1462S-1476S.
Crossref
N MisawaY SatomiK KondoA YokoyamaS KajiwaraT SaitoT OhtaniW Miki. (1995) Structure and functional analysis of a marine bacterial carotenoid biosynthesis gene cluster and astaxanthin biosynthetic pathway proposed at the gene level. Journal of Bacteriology 177:22, pages 6575-6584.
Crossref
Susumu Kajiwara, Toshihide Kakizono, Toshiko Saito, Keiji Kondo, Takeshi Ohtani, Naomichi Nishio, Shiro Nagai & Norihiko Misawa. (1995) Isolation and functional identification of a novel cDNA for astaxanthin biosynthesis from Haematococcus pluvialis, and astaxanthin synthesis in Escherichia coli. Plant Molecular Biology 29:2, pages 343-352.
Crossref
C E Taylor. (1995) Cytokines as adjuvants for vaccines: antigen-specific responses differ from polyclonal responses. Infection and Immunity 63:9, pages 3241-3244.
Crossref
Akihiro Yokoyama & Wataru Miki. (1995) Composition and presumed biosynthetic pathway of carotenoids in the astaxanthin-producing bacterium Agrobacterium aurantiacum . FEMS Microbiology Letters 128:2, pages 139-144.
Crossref
Eric A. Johnson & William A. Schroeder. 1996. Downstream Processing Biosurfactants Carotenoids. Downstream Processing Biosurfactants Carotenoids 119 178 .
I. T. Johnson, G. Williamson & S. R. R. Musk. (2007) Anticarcinogenic Factors in Plant Foods: A New Class of Nutrients?. Nutrition Research Reviews 7:1, pages 175-204.
Crossref

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