Citations (65)
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Read on this site (11)
Ann R. Kennedy. (2023) Proteases, protease inhibitors and radiation carcinogenesis. International Journal of Radiation Biology 99:6, pages 882-890.
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Gabriela Paun, Simona Carmen Litescu, Elena Neagu, Andreia Tache & Gabriel Lucian Radu. (2014) Evaluation of Geranium spp., Helleborus spp. and Hyssopus spp. polyphenolic extracts inhibitory activity against urease and α-chymotrypsin. Journal of Enzyme Inhibition and Medicinal Chemistry 29:1, pages 28-34.
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PamelaJ. Magee, Richard Owusu-Apenten, MarkJ. McCann, ChrisI. Gill & IanR. Rowland. (2012) Chickpea (Cicer arietinum) and Other Plant-Derived Protease Inhibitor Concentrates Inhibit Breast and Prostate Cancer Cell Proliferation In Vitro. Nutrition and Cancer 64:5, pages 741-748.
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DavidL. McCormick, WilliamD. Johnson, MaartenC. Bosland, RonaldA. Lubet & VernonE. Steele. (2007) Chemoprevention of Rat Prostate Carcinogenesis by Soy Isoflavones and by Bowman-Birk Inhibitor. Nutrition and Cancer 57:2, pages 184-193.
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Ann R. Kennedy, Paul C. Billings, X. Steven Wan & Paul M. Newberne. (2002) Effects of Bowman-Birk Inhibitor on Rat Colon Carcinogenesis. Nutrition and Cancer 43:2, pages 174-186.
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X. Steven Wan, David G. Serota, Jeffrey H. Ware, James A. Crowell & Ann R. Kennedy. (2002) Detection of Bowman-Birk Inhibitor and Anti-Bowman-Birk Inhibitor Antibodies in Sera of Humans and Animals Treated With Bowman-Birk Inhibitor Concentrate. Nutrition and Cancer 43:2, pages 167-173.
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Jeffrey H. Ware, X. Steven Wan & Ann R. Kennedy. (1999) Bowman-Birk Inhibitor Suppresses Production of Superoxide Anion Radicals in Differentiated HL-60 Cells. Nutrition and Cancer 33:2, pages 174-177.
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Lili Zhang, X. Steven Wan, Jeremiah J. Donahue, Jeffrey H. Ware & Ann R. Kennedy. (1999) Effects of the Bowman-Birk Inhibitor on Clonogenic Survival and Cisplatin- or Radiation-Induced Cytotoxicity in Human Breast, Cervical, and Head and Neck Cancer Cells. Nutrition and Cancer 33:2, pages 165-173.
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X. Steven Wan, ThomasC. Hamilton, JeffreyH. Ware, JeremiahJ. Donahue & AnnR. Kennedy. (1998) Growth inhibition and cytotoxicity induced by Bowman‐Birk inhibitor concentrate in cisplatin‐resistant human ovarian cancer cells. Nutrition and Cancer 31:1, pages 8-17.
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ChristopherW. Kennedy, JeremiahJ. Donahue & X. Steven Wan. (1996) Effects of the bowman‐Birk protease inhibitor on survival of fibroblasts and cancer cells exposed to radiation and cis‐platinum. Nutrition and Cancer 26:2, pages 209-217.
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PatriciaA. Maki, Yvonne Paterson & AnnR. Kennedy. (1994) Studies related to the potential antigenicity of the Bowman‐Birk inhibitor, an anticarcinogenic protease inhibitor isolated from soybeans. Nutrition and Cancer 22:2, pages 185-193.
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Articles from other publishers (54)
Abigail Raffner Basson, Saleh Ahmed, Rawan Almutairi, Brian Seo & Fabio Cominelli. (2021) Regulation of Intestinal Inflammation by Soybean and Soy-Derived Compounds. Foods 10:4, pages 774.
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Agata Gitlin-Domagalska, Aleksandra Maciejewska & Dawid Dębowski. (2020) Bowman-Birk Inhibitors: Insights into Family of Multifunctional Proteins and Peptides with Potential Therapeutical Applications. Pharmaceuticals 13:12, pages 421.
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Kenneth L. Bost & Kenneth J. Piller. 2020. Mucosal Vaccines. Mucosal Vaccines
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382
.
Arindam Barman, Chinky M. Marak, Rituparna Mitra Barman & Cheana S. Sangma. 2019. Legume Seed Nutraceutical Research. Legume Seed Nutraceutical Research.
Tong-Cui Ma, Le Guo, Run-Hong Zhou, Xu Wang, Jin-Biao Liu, Jie-Liang Li, Yu Zhou, Wei Hou & Wen-Zhe Ho. (2018) Soybean-derived Bowman-Birk inhibitor (BBI) blocks HIV entry into macrophages. Virology 513, pages 91-97.
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Tooba Naz Shamsi, Romana Parveen & Sadaf Fatima. (2016) Characterization, biomedical and agricultural applications of protease inhibitors: A review. International Journal of Biological Macromolecules 91, pages 1120-1133.
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Hari B. Krishnan & Thomas T.Y. Wang. (2015) An effective and simple procedure to isolate abundant quantities of biologically active chemopreventive Lunasin Protease Inhibitor Concentrate (LPIC) from soybean. Food Chemistry 177, pages 120-126.
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LILIE L. LIN, ROSEMARIE MICK, JEFFREY WARE, JAMES METZ, ROBERT LUSTIG, NEHA VAPIWALA, RAMESH RENGAN & ANN R. KENNEDY. (2014) Phase I randomized double-blind placebo-controlled single-dose safety studies of Bowman-Birk inhibitor concentrate. Oncology Letters 7:4, pages 1151-1158.
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William B. Armstrong, Thomas H. Taylor, Ann R. Kennedy, Raymond J. Melrose, Diana V. Messadi, Mai Gu, Anh D. Le, Marjorie Perloff, Francisco Civantos, William Jarrard Goodwin, Lori J. Wirth, Alexander Ross Kerr & Frank L. MeyskensJrJr. (2013) Bowman Birk Inhibitor Concentrate and Oral Leukoplakia: A Randomized Phase IIb Trial. Cancer Prevention Research 6:5, pages 410-418.
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Lara Moussa, Valérie Bézirard, Christel Salvador-Cartier, Valérie Bacquié, Eric Houdeau & Vassilia Théodorou. (2013) A new soy germ fermented ingredient displays estrogenic and protease inhibitor activities able to prevent irritable bowel syndrome-like symptoms in stressed female rats. Clinical Nutrition 32:1, pages 51-58.
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Miryam Amigo-Benavent, Chiara Nitride, Laura Bravo, Pasquale Ferranti & M. Dolores del Castillo. (2013) Stability and bioactivity of a Bowman–Birk inhibitor in orange juice during processing and storage. Food & Function 4:7, pages 1051.
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Ann R. Kennedy. 2013. Antitumor Potential and other Emerging Medicinal Properties of Natural Compounds. Antitumor Potential and other Emerging Medicinal Properties of Natural Compounds
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186
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Alfonso Clemente, M. Carmen Marín-Manzano, Elisabeth Jiménez, M. Carmen Arques & Claire Domoney. (2012)
The anti-proliferative effect of TI1B, a major Bowman–Birk isoinhibitor from pea (
Pisum sativum
L.), on HT29 colon cancer cells is mediated through protease inhibition
. British Journal of Nutrition 108:S1, pages S135-S144.
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A.R. Kennedy & X.S. Wan. (2011) Countermeasures for space radiation induced adverse biologic effects. Advances in Space Research 48:9, pages 1460-1479.
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Micaela Rocco, Livia Malorni, Angela Chambery, Elia Poerio, Augusto Parente & Antimo Di Maro. (2011) A Bowman–Birk inhibitor with anti-elastase activity from Lathyrus sativus L. seeds. Molecular BioSystems 7:8, pages 2500.
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C. A. Morris, J. T. Selsby, L. D. Morris, K. Pendrak & H. L. Sweeney. (2010) Bowman-Birk inhibitor attenuates dystrophic pathology in mdx mice. Journal of Applied Physiology 109:5, pages 1492-1499.
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Soghra Khatun Haq, Gulam Rabbani, Ejaz Ahmad, Sheikh Muhammad Atif & Rizwan Hasan Khan. (2010) Protease inhibitors: A panacea?. Journal of Biochemical and Molecular Toxicology 24:4, pages 270-277.
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James G. Davis, X. Steven Wan, Jeffrey H. Ware & Ann R. Kennedy. (2010) Dietary Supplements Reduce the Cataractogenic Potential of Proton and HZE-Particle Radiation in Mice. Radiation Research 173:3, pages 353-361.
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Alfonso Clemente, Francisco Javier Moreno, Maria del Carmen Marín‐Manzano, Elisabeth Jiménez & Claire Domoney. (2010)
The cytotoxic effect of Bowman–Birk isoinhibitors, IBB1 and IBBD2, from soybean (
Glycine max
) on HT29 human colorectal cancer cells is related to their intrinsic ability to inhibit serine proteases
. Molecular Nutrition & Food Research 54:3, pages 396-405.
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Ann R. Kennedy. (2009) FACTORS THAT MODIFY RADIATION-INDUCED CARCINOGENESIS. Health Physics 97:5, pages 433-445.
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Ann R. Kennedy. 2009. Chemoprevention of Cancer and DNA Damage by Dietary Factors. Chemoprevention of Cancer and DNA Damage by Dietary Factors
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767
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Tarik Touil, Bogoljub Ciric, Elvira Ventura, Kenneth S. Shindler, Bruno Gran & Abdolmohamad Rostami. (2008) Bowman–Birk inhibitor suppresses autoimmune inflammation and neuronal loss in a mouse model of multiple sclerosis. Journal of the Neurological Sciences 271:1-2, pages 191-202.
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Klaus Dittmann, Claus Mayer, Rainer Kehlbach & H. Peter Rodemann. (2008) The radioprotector Bowman–Birk proteinase inhibitor stimulates DNA repair via epidermal growth factor receptor phosphorylation and nuclear transport. Radiotherapy and Oncology 86:3, pages 375-382.
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Gary R. Lichtenstein, Julius J. Deren, Seymour Katz, James D. Lewis, Ann R. Kennedy & Jeffrey H. Ware. (2007) Bowman-Birk Inhibitor Concentrate: A Novel Therapeutic Agent for Patients with Active Ulcerative Colitis. Digestive Diseases and Sciences 53:1, pages 175-180.
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Sandrine Arbogast, Jacqueline Smith, Yves Matuszczak, Brian J. Hardin, Jennifer S. Moylan, Jeffrey D. Smith, Jeffrey Ware, Ann R. Kennedy & Michael B. Reid. (2007) Bowman-Birk inhibitor concentrate prevents atrophy, weakness, and oxidative stress in soleus muscle of hindlimb-unloaded mice. Journal of Applied Physiology 102:3, pages 956-964.
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B GranN Tabibzadeh, A Martin, E S Ventura, J H Ware, G-X Zhang, J L Parr, A R Kennedy & A M Rostami. (2016) The protease inhibitor, Bowman-Birk Inhibitor, suppresses experimental autoimmune encephalomyelitis: a potential oral therapy for multiple sclerosis. Multiple Sclerosis Journal 12:6, pages 688-697.
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Carl A. Morris, Linda D. Morris, Ann R. Kennedy & H. Lee Sweeney. (2005) Attenuation of skeletal muscle atrophy via protease inhibition. Journal of Applied Physiology 99:5, pages 1719-1727.
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Mark Morse & Gary Stoner. 2005. Molecular Carcinogenesis and the Molecular Biology of Human Cancer. Molecular Carcinogenesis and the Molecular Biology of Human Cancer
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478
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Ann Kennedy. 2005. Soy in Health and Disease Prevention. Soy in Health and Disease Prevention
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223
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E.O Farombi, M Hansen, G Ravn-Haren, P Møller & L.O Dragsted. (2004) Commonly consumed and naturally occurring dietary substances affect biomarkers of oxidative stress and DNA damage in healthy rats. Food and Chemical Toxicology 42:8, pages 1315-1322.
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Alfonso Clemente, Donald A MacKenzie, David J Jeenes & Claire Domoney. (2004) The effect of variation within inhibitory domains on the activity of pea protease inhibitors from the Bowman–Birk class. Protein Expression and Purification 36:1, pages 106-114.
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William B. Armstrong, X. Steven Wan, Ann R. Kennedy, Thomas H. Taylor & Frank L. MeyskensJr.Jr.. (2010) Development of the Bowman‐Birk inhibitor for oral cancer chemoprevention and analysis of neu immunohistochemical staining intensity with Bowman‐Birk inhibitor concentrate treatment. The Laryngoscope 113:10, pages 1687-1702.
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Alfonso Clemente, Donald MacKenzie, David Jeenes, Jenny Gee, Ian Johnson & Claire Domoney. 2003. Plant Biotechnology 2002 and Beyond. Plant Biotechnology 2002 and Beyond
429
431
.
S. Bruce Malkowicz, Shih‐Ping Liu, Gregory A. Broderick, Alan J. Wein, Ann R. Kennedy & Robert M. Levin. (2002) Effect of the Bowman‐Birk inhibitor (a soy protein) on in vitro bladder neck/urethral and penile corporal smooth muscle activity. Neurourology and Urodynamics 22:1, pages 54-57.
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Hanspeter Witschi & Imelda Espiritu. (2002) Development of tobacco smoke-induced lung tumors in mice fed Bowman-Birk protease inhibitor concentrate (BBIC). Cancer Letters 183:2, pages 141-146.
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T. Garcı́a-Gasca, L.A. Salazar-Olivo, E. Mendiola-Olaya & A. Blanco-Labra. (2002) The effects of a protease inhibitor fraction from tepary bean (Phaseolus acutifolius) on in vitro cell proliferation and cell adhesion of transformed cells. Toxicology in Vitro 16:3, pages 229-233.
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Ann R. Kennedy & X. Steven Wan. (2002) Effects of the Bowman‐Birk inhibitor on growth, invasion, and clonogenic survival of human prostate epithelial cells and prostate cancer cells*. The Prostate 50:2, pages 125-133.
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FRANK L. MEYSKENSJR.JR.. (2001) Development of Bowman-Birk Inhibitor for Chemoprevention of Oral Head and Neck Cancer. Annals of the New York Academy of Sciences 952:1, pages 116-123.
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David J. Sessa & Walter J Wolf. (2001) Bowman–Birk inhibitors in soybean seed coats. Industrial Crops and Products 14:1, pages 73-83.
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S. Bruce Malkowicz, W. Gillies McKenna, David J. Vaughn, X. Steven Wan, Kathleen J. Propert, Kenneth Rockwell, Sheldon H.F. Marks, Alan J. Wein & Ann R. Kennedy. (2001) Effects of Bowman–Birk inhibitor concentrate (BBIC) in patients with benign prostatic hyperplasia*†. The Prostate 48:1, pages 16-28.
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Anthony W Tolcher, Ann Kennedy, Robert J Padley, Noreen Majeed, Michael Pollak & Philip W Kantoff. (2001) Other novel agents: Rationale and current status as chemopreventive agents. Urology 57:4, pages 86-89.
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Mary Jean Sawey. (2001) Role of Gap-Junctional Communication in Breast Cancer Progression and Chemoprevention. The Journal of Nutrition 131:1, pages 167S-169S.
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David B. Fournier, John W. ErdmanJr.Jr. & Gary B. Gordon. 2001. Primary and Secondary Preventive Nutrition. Primary and Secondary Preventive Nutrition
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54
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Elizabeth M. T. de Souza. (2000) Journal of Protein Chemistry 19:6, pages 507-513.
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X. Steven Wan, Jeffrey H. Ware, Lili Zhang, Paul M. Newberne, Sydney M. Evans, Larry C. Clark & Ann R. Kennedy. (1999) Treatment with soybean-derived Bowman Birk inhibitor increases serum prostate-specific antigen concentration while suppressing growth of human prostate cancer xenografts in nude mice. The Prostate 41:4, pages 243-252.
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Ann R Kennedy. (1998) The Bowman-Birk inhibitor from soybeans as an anticarcinogenic agent. The American Journal of Clinical Nutrition 68:6, pages 1406S-1412S.
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Ann R. Kennedy. (1998) Chemopreventive Agents. Pharmacology & Therapeutics 78:3, pages 167-209.
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Jeffrey H. Ware, X.Steven Wan, Harvey Rubin, Norman M. Schechter & Ann R. Kennedy. (1997) Soybean Bowman–Birk Protease Inhibitor Is a Highly Effective Inhibitor of Human Mast Cell Chymase. Archives of Biochemistry and Biophysics 344:1, pages 133-138.
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Sonia M de Freitas, Luciane V de Mello, Maria Cristina M da Silva, Gerrit Vriend, Goran Neshich & Manuel M Ventura. (1997) Analysis of the black-eyed pea trypsin and chymotrypsin inhibitor-α-chymotrypsin complex. FEBS Letters 409:2, pages 121-127.
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Z. EL-SHAMEI, J.W. WU & N.F. HAARD. (1996) INFLUENCE OF WOUND INJURY ON ACCUMULATION OF PROTEINASE INHIBITORS IN LEAF AND STEM TISSUES OF TWO PROCESSING TOMATO CULTIVARS. Journal of Food Biochemistry 20:5, pages 155-171.
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Ann R. Kennedy. (1996) A Reply to Liener. The Journal of Nutrition 126:2, pages 584-585.
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X. Steven Wan, Cameron J. Koch, Edith M. Lord, Holly Manzone, Paul C. Billings, Jeremiah J. Donahue, Carolyn S. Odell, John H. Miller, Norman A. Schmidt & Ann R. Kennedy. (1995) Monoclonal antibodies differentially reactive with native and reductively modified Bowman-Birk protease inhibitor. Journal of Immunological Methods 180:1, pages 117-130.
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Ann R. Kennedy & Holly Manzone. (1995) Effects of protease inhibitors on levels of proteolytic activity in normal and premalignant cells and tissues. Journal of Cellular Biochemistry 59:S22, pages 188-194.
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Bozidar Stavric. (1994) Role of chemopreventers in human diet. Clinical Biochemistry 27:5, pages 319-332.
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