38
Views
89
CrossRef citations to date
0
Altmetric
Reports

Urinary Lignan and isoflavonoid excretion in men and women consuming vegetable and soy diets

, , , &
Pages 1-12 | Received 28 Sep 1994, Accepted 23 Feb 1995, Published online: 04 Aug 2009

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (11)

Qixing Nie, Mengmeng Xing, Jielun Hu, Xiaojuan Hu, Shaoping Nie & Mingyong Xie. (2017) Metabolism and health effects of phyto-estrogens. Critical Reviews in Food Science and Nutrition 57:11, pages 2432-2454.
Read now
Shin-ichiro YOKOYAMA & Tohru SUZUKI. (2008) Isolation and Characterization of a Novel Equol-Producing Bacterium from Human Feces. Bioscience, Biotechnology, and Biochemistry 72:10, pages 2660-2666.
Read now
D. B. Clarke & A. S. Lloyd. (2004) Dietary exposure estimates of isoflavones from the 1998 UK Total Diet Study. Food Additives & Contaminants 21:4, pages 305-316.
Read now
Lon R. White, Helen Petrovitch, G. Webster Ross, Kamal Masaki, John Hardman, James Nelson, Daron Davis & William Markesbery. (2000) Brain Aging and Midlife Tofu Consumption. Journal of the American College of Nutrition 19:2, pages 242-255.
Read now
Fortune Kohen, Batya Gayer, Yehudith Amir-Zaltsman, Herzl Ben-Hur, Emily Thomas & Lee-Jane W. Lu. (1999) A Nonisotopic Enzyme-Based Immunoassay for Assessing Human Exposure to Genistein. Nutrition and Cancer 35:1, pages 96-103.
Read now
Zhi Chen, Wei Zheng, LaurieJ. Custer, Qi Dai, Xiao‐Ou Shu, Fan Jin & AdrianA. Franke. (1999) Usual dietary consumption of soy foods and its correlation with the excretion rate of isoflavonoids in overnight urine samples among Chinese women in shanghai. Nutrition and Cancer 33:1, pages 82-87.
Read now
SuzanneM. Shoff, PollyA. Newcomb, JulieA. Mares‐Perlman, BarbaraE.K. Klein, StevenM. Haffner, BarryE. Storer & Ronald Klein. (1998) Usual consumption of plant foods containing phytoestrogens and sex hormone levels in postmenopausal women in Wisconsin. Nutrition and Cancer 30:3, pages 207-212.
Read now
Herman Adlercreutz & Witold Mazur. (1997) Phyto-oestrogens and Western Diseases. Annals of Medicine 29:2, pages 95-120.
Read now
PaulaD. Nesbitt & LilianU. Thompson. (1997) Lignans in homemade and commercial products containing flaxseed. Nutrition and Cancer 29:3, pages 222-227.
Read now
Joanne Slavin, David Jacobs & Leonard Marquart. (1997) Whole‐grain consumption and chronic disease: Protective mechanisms. Nutrition and Cancer 27:1, pages 14-21.
Read now

Articles from other publishers (78)

Sara Motyka, Karolina Jafernik, Halina Ekiert, Javad Sharifi-Rad, Daniela Calina, Basem Al-Omari, Agnieszka Szopa & William C. Cho. (2023) Podophyllotoxin and its derivatives: Potential anticancer agents of natural origin in cancer chemotherapy. Biomedicine & Pharmacotherapy 158, pages 114145.
Crossref
Qinghua Cui, Ruikun Du, Miaomiao Liu & Lijun Rong. (2020) Lignans and Their Derivatives from Plants as Antivirals. Molecules 25:1, pages 183.
Crossref
Pedapati S. C. Sri Harsha, Roshaida Abdul Wahab, Mar Garcia-Aloy, Francisco Madrid-Gambin, Sheila Estruel-Amades, Bernhard Watzl, Cristina Andrés-Lacueva & Lorraine Brennan. (2018) Biomarkers of legume intake in human intervention and observational studies: a systematic review. Genes & Nutrition 13:1.
Crossref
Dafne García-Mateos, Rocío García-Villalba, Jon A. Otero, José A. Marañón, Juan C. Espín, Ana I. Álvarez & Gracia Merino. (2018) An altered tissue distribution of flaxseed lignans and their metabolites in Abcg2 knockout mice. Food & Function 9:1, pages 636-642.
Crossref
Karina Chávez-Suárez, María Ortega-Vélez, Ana Valenzuela-Quintanar, Marcia Galván-Portillo, Lizbeth López-Carrillo, Julián Esparza-Romero, María Saucedo-Tamayo, María Robles-Burgueño, Susana Palma-Durán, María Gutiérrez-Coronado, Melissa Campa-Siqueiros, Patricia Grajeda-Cota & Graciela Caire-Juvera. (2017) Phytoestrogen Concentrations in Human Urine as Biomarkers for Dietary Phytoestrogen Intake in Mexican Women. Nutrients 9:10, pages 1078.
Crossref
Xiaoling Song, Ying Huang, Marian L Neuhouser, Lesley F Tinker, Mara Z Vitolins, Ross L Prentice & Johanna W Lampe. (2017) Dietary long-chain fatty acids and carbohydrate biomarker evaluation in a controlled feeding study in participants from the Women’s Health Initiative cohort ,. The American Journal of Clinical Nutrition 105:6, pages 1272-1282.
Crossref
Johanna W Lampe, Ying Huang, Marian L Neuhouser, Lesley F Tinker, Xiaoling Song, Dale A Schoeller, Soyoung Kim, Daniel Raftery, Chongzhi Di, Cheng Zheng, Yvonne Schwarz, Linda Van Horn, Cynthia A Thomson, Yasmin Mossavar-Rahmani, Shirley AA Beresford & Ross L Prentice. (2017) Dietary biomarker evaluation in a controlled feeding study in women from the Women’s Health Initiative cohort ,. The American Journal of Clinical Nutrition 105:2, pages 466-475.
Crossref
Amanda J. Cross, Johanna W. Lampe, Cheryl L. Rock & Carol J. Boushey. 2017. Nutrition in the Prevention and Treatment of Disease. Nutrition in the Prevention and Treatment of Disease 217 234 .
Seth C. Yoder, Samuel M. Lancaster, Meredith A.J. Hullar & Johanna W. Lampe. 2015. Diet-Microbe Interactions in the Gut. Diet-Microbe Interactions in the Gut 103 117 .
Ilaria Campesi, Annalisa Romani, Maria Marino & Flavia Franconi. 2014. Recent Advances in Polyphenol Research. Recent Advances in Polyphenol Research 327 339 .
Tina Sehm, Zheng Fan, Ruth Weiss, Marc Schwarz, Tobias Engelhorn, Nirjhar Hore, Arnd Doerfler, Michael Buchfelder, IIker Y. Eyüpoglu & Nic E. Savaskan. (2014) The impact of dietary isoflavonoids on malignant brain tumors. Cancer Medicine 3:4, pages 865-877.
Crossref
Amanda J. Cross, Johanna W. Lampe & Cheryl L. Rock. 2013. Nutrition in the Prevention and Treatment of Disease. Nutrition in the Prevention and Treatment of Disease 209 225 .
Toktam Mohammadpour. (2012) Estrogen-dependent effect of soy extract on pentylenetetrazole-induced seizures in rats. Journal of Chinese Integrative Medicine 10:12, pages 1470-1475.
Crossref
Nina Føns Johnsen, Anja Olsen, Birthe Lykke Riegels Thomsen, Jane Christensen, Rikke Egeberg, Knud Erik Bach Knudsen, Steffen Loft, Kim Overvad & Anne Tjønneland. (2009) Plasma enterolactone and risk of colon and rectal cancer in a case–cohort study of Danish men and women. Cancer Causes & Control 21:1, pages 153-162.
Crossref
Christopher D. Gardner, Lorraine M. Chatterjee & Adrian A. Franke. (2009) Effects of isoflavone supplements vs. soy foods on blood concentrations of genistein and daidzein in adults. The Journal of Nutritional Biochemistry 20:3, pages 227-234.
Crossref
Ock Kyoung Chun, Sang Jin Chung & Won O. Song. (2009) Urinary Isoflavones and Their Metabolites Validate the Dietary Isoflavone Intakes in US Adults. Journal of the American Dietetic Association 109:2, pages 245-254.
Crossref
L I Mennen, D Sapinho, H Ito, P Galan, S Hercberg & A Scalbert. (2007) Urinary excretion of 13 dietary flavonoids and phenolic acids in free-living healthy subjects – variability and possible use as biomarkers of polyphenol intake. European Journal of Clinical Nutrition 62:4, pages 519-525.
Crossref
Timothy Murray, Jinguo Kang, Lee Astheimer & William E. Price. (2007) Tissue Distribution of Lignans in Rats in Response to Diet, Dose−Response, and Competition with Isoflavones. Journal of Agricultural and Food Chemistry 55:12, pages 4907-4912.
Crossref
Shin-ichiro YOKOYAMA & Tsuyoshi KUZUGUCHI. (2007) Rapid and Convenient Detection of Urinary Equol by Thin-Layer Chromatography. Journal of Nutritional Science and Vitaminology 53:1, pages 43-47.
Crossref
Mary H. McMullenJill M. Hamilton-ReevesMelissa J.L. BonordenKerry E. WangenWilliam R. PhippsJoellen M. FeirtagMindy S. Kurzer. (2006) Consumption of Lactobacillus acidophilus and Bifidobacterium longum Does Not Alter Phytoestrogen Metabolism and Plasma Hormones in Men: A Pilot Study . The Journal of Alternative and Complementary Medicine 12:9, pages 887-894.
Crossref
Ajita V. Singh, Adrian A. Franke, George L. Blackburn & Jin-Rong Zhou. (2006) Soy Phytochemicals Prevent Orthotopic Growth and Metastasis of Bladder Cancer in Mice by Alterations of Cancer Cell Proliferation and Apoptosis and Tumor Angiogenesis. Cancer Research 66:3, pages 1851-1858.
Crossref
Jayne V. Woodside, Michael S. Morton, Alethea Cooper & Anthony J.C. Leathem. (2006) Short-term consumption of phytoestrogen-rich foods in humans alters dietary macro- and micronutrient intake. Nutrition Research 26:1, pages 7-10.
Crossref
Anneleen Kuijsten, Ilja C.W. Arts, Pieter van’t Veer & Peter C.H. Hollman. (2005) The Relative Bioavailability of Enterolignans in Humans Is Enhanced by Milling and Crushing of Flaxseed. The Journal of Nutrition 135:12, pages 2812-2816.
Crossref
Aedín Cassidy. (2007) Dietary phyto-oestrogens: molecular mechanisms, bioavailability and importance to menopausal health. Nutrition Research Reviews 18:2, pages 183-201.
Crossref
Liza Valentín-Blasini, Melissa A Sadowski, Donna Walden, Lisa Caltabiano, Larry L Needham & Dana B Barr. (2005) Urinary phytoestrogen concentrations in the U.S. population (1999–2000). Journal of Exposure Science & Environmental Epidemiology 15:6, pages 509-523.
Crossref
Charlotte Atkinson, Cara L. Frankenfeld & Johanna W. Lampe. (2016) Gut Bacterial Metabolism of the Soy Isoflavone Daidzein: Exploring the Relevance to Human Health. Experimental Biology and Medicine 230:3, pages 155-170.
Crossref
S J Blakesmith, P M Lyons-Wall, G E Joannou, P Petocz & S Samman. (2004) Urinary isoflavonoid excretion is inversely associated with the ratio of protein to dietary fibre intake in young women. European Journal of Clinical Nutrition 59:2, pages 284-290.
Crossref
Heather Patisaul & Patricia Whitten. 2004. Endocrine Disruptors. Endocrine Disruptors 135 173 .
Helen Wiseman, Karen Casey, Elizabeth A Bowey, Rosanna Duffy, Margaret Davies, Ian R Rowland, Antony S Lloyd, Alistair Murray, Richard Thompson & Don B Clarke. (2004) Influence of 10 wk of soy consumption on plasma concentrations and excretion of isoflavonoids and on gut microflora metabolism in healthy adults. The American Journal of Clinical Nutrition 80:3, pages 692-699.
Crossref
C. L. Frankenfeld, C. Atkinson, W. K. Thomas, E. L. Goode, A. Gonzalez, T. Jokela, K. Wähälä, S. M. Schwartz, S. S. Li & J. W. Lampe. (2016) Familial Correlations, Segregation Analysis, and Nongenetic Correlates of Soy Isoflavone–Metabolizing Phenotypes. Experimental Biology and Medicine 229:9, pages 902-913.
Crossref
Nina F. Johnsen, Helene Hausner, Anja Olsen, Inge Tetens, Jane Christensen, Knud Erik Bach Knudsen, Kim Overvad & Anne Tjønneland. (2004) Intake of Whole Grains and Vegetables Determines the Plasma Enterolactone Concentration of Danish Women. The Journal of Nutrition 134:10, pages 2691-2697.
Crossref
Marian S. Faughnan, Ann Hawdon, Eric Ah-Singh, Jonathan Brown, D. J. Millward & Aedin Cassidy. (2007) Urinary isoflavone kinetics: the effect of age, gender, food matrix and chemical composition. British Journal of Nutrition 91:4, pages 567-574.
Crossref
Aynun Nahar Begum, Catherine Nicolle, Christian Rémésy, Augustin Scalbert, Isabelle Mila, Catherine Lapierre, Kazutane Nagano, Kazuhiko Fukushima, Satu-Maarit Heinonen & Herman Adlercreutz. (2004) Dietary Lignins Are Precursors of Mammalian Lignans in Rats. The Journal of Nutrition 134:1, pages 120-127.
Crossref
Andrea Hutchins a & Joanne Slavinb b. 2003. Flaxseed in Human Nutrition, Second Edition. Flaxseed in Human Nutrition, Second Edition.
Robert M. Blair, Susan E. Appt, Thomas B. Clarkson & Adrian A. Franke. (2003) Treatment with Antibiotics Reduces Plasma Equol Concentration in Cynomolgus Monkeys (Macaca fascicularis). The Journal of Nutrition 133:7, pages 2262-2267.
Crossref
Liza Valentín-Blasini, Benjamin C Blount, Samuel P Caudill & Larry L Needham. (2003) Urinary and serum concentrations of seven phytoestrogens in a human reference population subset. Journal of Exposure Science & Environmental Epidemiology 13:4, pages 276-282.
Crossref
Ian Rowland, Marian Faughnan, Leane Hoey, Kristiina Wähälä, Gary Williamson & Aedin Cassidy. (2011) Bioavailability of phyto-oestrogens. British Journal of Nutrition 89:S1, pages S45-S58.
Crossref
Antti A. Hoikkala, Emidio Schiavoni & Kristiina Wähälä. (2011) Analysis of phyto-oestrogens in biological matrices. British Journal of Nutrition 89:S1, pages S5-S18.
Crossref
Kenneth D.R. Setchell, Nadine Maynard Brown, Pankaj B. Desai, Linda Zimmer-Nechimias, Brian Wolfe, Abhijeet S. Jakate, Vivian Creutzinger & James E. Heubi. (2003) Bioavailability, Disposition, and Dose-Response Effects of Soy Isoflavones When Consumed by Healthy Women at Physiologically Typical Dietary Intakes. The Journal of Nutrition 133:4, pages 1027-1035.
Crossref
Johanna W. Lampe. (2003) Isoflavonoid and Lignan Phytoestrogens as Dietary Biomarkers. The Journal of Nutrition 133:3, pages 956S-964S.
Crossref
S. KREIJKAMP-KASPERS & Y.T. VAN DER SCHOUW. 2003. Performance Functional Foods. Performance Functional Foods 61 77 .
Sam J Bhathena & Manuel T Velasquez. (2002) Beneficial role of dietary phytoestrogens in obesity and diabetes. The American Journal of Clinical Nutrition 76:6, pages 1191-1201.
Crossref
Catherine Nicolle, Claudine Manach, Christine Morand, Witold Mazur, Herman Adlercreutz, Christian Rémésy & Augustin Scalbert. (2002) Mammalian Lignan Formation in Rats Fed a Wheat Bran Diet. Journal of Agricultural and Food Chemistry 50:21, pages 6222-6226.
Crossref
E. Venturelli, S. Rinaldi, M. Cambiè, A. Cavalleri & G. Secreto. (2018) Quantitative Analysis of Urinary Daidzein and Equol by Gas Chromatography after Solid-Phase Extraction and High-Performance Liquid Chromatography. The International Journal of Biological Markers 17:3, pages 182-188.
Crossref
Michelle P. Warren, Barbara Shortle & Jennifer E. Dominguez. (2002) Use of alternative therapies in menopause. Best Practice & Research Clinical Obstetrics & Gynaecology 16:3, pages 411-448.
Crossref
Jill Nicholls, Barbara O. Schneeman, Bill L. Lasley, Steven T. Nakajima & Kenneth D.R. Setchell. (2002) Effects of Soy Consumption on Gonadotropin Secretion and Acute Pituitary Responses to Gonadotropin-Releasing Hormone in Women. The Journal of Nutrition 132:4, pages 708-714.
Crossref
John Roboz. 2002. Mass Spectrometry in Cancer Research. Mass Spectrometry in Cancer Research 201 360 .
Susan R. Davis. 2002. Selective Estrogen Receptor Modulators. Selective Estrogen Receptor Modulators 345 363 .
C. P. Wild, C. Andersson, N. M. O'Brien, L. Wilson & J. A. Woods. (2007) A critical evaluation of the application of biomarkers in epidemiological studies on diet and health. British Journal of Nutrition 86:S1, pages S37-S53.
Crossref
Mary Satterfield, David M Black & Jennifer S Brodbelt. (2001) Detection of the isoflavone aglycones genistein and daidzein in urine using solid-phase microextraction–high-performance liquid chromatography–electrospray ionization mass spectrometry. Journal of Chromatography B: Biomedical Sciences and Applications 759:1, pages 33-41.
Crossref
Manuel T. Velasquez & Sam J. Bhathena. (2001) Dietary phytoestrogens: A possible role in renal disease protection. American Journal of Kidney Diseases 37:5, pages 1056-1068.
Crossref
Johanna W. Lampe, Heather E. Skor, Sue Li, Kristiina Wähälä, William N. Howald & Chu Chen. (2001) Wheat Bran and Soy Protein Feeding Do Not Alter Urinary Excretion of the Isoflavan Equol in Premenopausal Women. The Journal of Nutrition 131:3, pages 740-744.
Crossref
Lynette Wroblewski Lissin & John P Cooke. (2000) Phytoestrogens and cardiovascular health. Journal of the American College of Cardiology 35:6, pages 1403-1410.
Crossref
R.S. Ward. 2000. Bioactive Natural Products (Part E). Bioactive Natural Products (Part E) 739 798 .
MICHELLE P. WARREN & RUSSALIND H. RAMOS. 2000. Menopause. Menopause 459 480 .
Susan R. Davis. 2000. Sex Hormone Replacement Therapy. Sex Hormone Replacement Therapy 83 107 .
Stefano Chimichi, Massimo Bambagiotti-Alberti, Silvia A. Coran, Valerio Giannellini & Boris Biddau. (1999) Complete assignment of the1H and13C NMR spectra of secoisolariciresinol diglucoside, a mammalian lignan precursor isolated fromLinum usitatissimum. Magnetic Resonance in Chemistry 37:11, pages 860-863.
Crossref
Jih-Tay Hsu, Wei-Lu Hsu & Chingwen Ying. (1999) Dietary phytoestrogen regulates estrogen receptor gene expression in human mammary carcinoma cells. Nutrition Research 19:10, pages 1447-1457.
Crossref
Jed W. Fahey, Beverly A. Clevidence & Robert M. Russell. (2009) Methods for Assessing the Biological Effects of Specific Plant Components. Nutrition Reviews 57:9, pages 34-40.
Crossref
Jih-Tay Hsu, Hsiao-Chiao Hung, Ching-Jung Chen, Wei-Lun Hsu & Chingwen Ying. (1999) Effects of the dietary phytoestrogen biochanin A on cell growth in the mammary carcinoma cell line MCF-7. The Journal of Nutritional Biochemistry 10:9, pages 510-517.
Crossref
Lucy P. Meagher, Gary R. Beecher, Vincent P. Flanagan & Betty W. Li. (1999) Isolation and Characterization of the Lignans, Isolariciresinol and Pinoresinol, in Flaxseed Meal. Journal of Agricultural and Food Chemistry 47:8, pages 3173-3180.
Crossref
Beverly D. Lyn-Cook, Heather L. Stottman, Yan Yan, Ernice Blann, Fred F. Kadlubar & George J. Hammons. (1999) The effects of phytoestrogens on human pancreatic tumor cells in vitro. Cancer Letters 142:1, pages 111-119.
Crossref
PHYLLIS KIRK, RUTH E PATTERSON & JOHANNA LAMPE. (1999) Development of a Soy Food Frequency Questionnaire to Estimate Isoflavone Consumption in US Adults. Journal of the American Dietetic Association 99:5, pages 558-563.
Crossref
Paula D Nesbitt, Yi Lam & Lilian U Thompson. (1999) Human metabolism of mammalian lignan precursors in raw and processed flaxseed. The American Journal of Clinical Nutrition 69:3, pages 549-555.
Crossref
Helen Wiseman. (2007) The bioavailability of non-nutrient plant factors: dietary flavonoids and phyto-oestrogens. Proceedings of the Nutrition Society 58:1, pages 139-146.
Crossref
John Birkbeck. 1999. Medical Importance of the Normal Microflora. Medical Importance of the Normal Microflora 262 294 .
Joshua D. Ford, Laurence B. Davin & Norman G. Lewis. 2000. Plant Polyphenols 2. Plant Polyphenols 2 675 694 .
Joanne L Slavin, Susan C Karr, Andrea M Hutchins & Johanna W Lampe. (1998) Influence of soybean processing, habitual diet, and soy dose on urinary isoflavonoid excretion. The American Journal of Clinical Nutrition 68:6, pages 1492S-1495S.
Crossref
Danielle F McMichael-Phillips, Claudia Harding, Mike Morton, Stephen A Roberts, Anthony Howell, Christopher S Potten & Nigel J Bundred. (1998) Effects of soy-protein supplementation on epithelial proliferation in the histologically normal human breast. The American Journal of Clinical Nutrition 68:6, pages 1431S-1436S.
Crossref
Susan R. Davis, Alice L. Murkies & Gisela Wilcox. (1998) Phytoestrogens in Clinical Practice. Integrative Medicine 1:1, pages 27-34.
Crossref
Lilian U. Thompson. (1998) 9Experimental studies on lignans and cancer. Baillière's Clinical Endocrinology and Metabolism 12:4, pages 691-705.
Crossref
Fabien S Dalais, Gregory E Rice, Mark L Wahlqvist, Bridget HH Hsu-Hage & Naiyana Wattanapenpaiboon. (1998) Urinary excretion of isoflavonoid phytoestrogens in Chinese and Anglo-Celtic populations in Australia. Nutrition Research 18:10, pages 1703-1709.
Crossref
H. Przyrembel. (1998) Natürliche Pflanzeninhaltsstoffe mit Wirkung auf das Hormonsystem. Bundesgesundheitsblatt 41:8, pages 335-340.
Crossref
Jörg Heilmann & Irmgard Merfort. (2006) Aktueller Kenntnisstand zum Metabolismus von Flavonoiden II. Resorption und Metabolismus von Flavonen, Flavanonen, Flavanen, Proanthocyanidinen und Isoflavonoiden. Pharmazie in unserer Zeit 27:4, pages 173-183.
Crossref
John J.B.^Anderson & Sanford C. Garner. (1997) The effects of phytoestrogens on bone. Nutrition Research 17:10, pages 1617-1632.
Crossref
SC Karr, JW Lampe, AM Hutchins & JL Slavin. (1997) Urinary isoflavonoid excretion in humans is dose dependent at low to moderate levels of soy-protein consumption. The American Journal of Clinical Nutrition 66:1, pages 46-51.
Crossref
Kenneth DR Setchell, Linda Zimmer-Nechemias, Jinnan Cai & James E Heubi. (1997) Exposure of infants to phyto-oestrogens from soy-based infant formula. The Lancet 350:9070, pages 23-27.
Crossref
Robert S. Ward. (1997) Lignans, neolignans and related compounds. Natural Product Reports 14:1, pages 43.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.