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Vitamin B6 suppresses growth and expression of albumin gene in a human hepatoma cell line HepG2

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Pages 206-211 | Received 02 Jan 1997, Accepted 06 May 1997, Published online: 04 Aug 2009

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Dai SHIMADA, Ayumi FUKUDA, Hiroaki KANOUCHI, Mitsuharu MATSUMOTO & Tatsuzo OKA. (2006) Vitamin B6 Suppresses Growth of the Feline Mammary Tumor Cell Line FRM. Bioscience, Biotechnology, and Biochemistry 70:4, pages 1038-1040.
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Dai Shimada, Ayumi Fukuda, Hiroaki Kawaguchi, Norihisa Kato, Hiroki Yoshida, Hiroaki Kanouchi & Tatsuzo Oka. (2005) Effect of High Dose of Pyridoxine on Mammary Tumorigenesis. Nutrition and Cancer 53:2, pages 202-207.
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Michael N. Viegas, Vincent Laizé, Maria A. Salgado, Carla Aguiar & Jorge Dias. (2019) Effect of Trace Minerals and B Vitamins on the Proliferation/Cytotoxicity and Mineralization of a Gilthead Seabream Bone–Derived Cell Line. Biological Trace Element Research 196:2, pages 629-638.
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L Galluzzi, E Vacchelli, J Michels, P Garcia, O Kepp, L Senovilla, I Vitale & G Kroemer. (2013) Effects of vitamin B6 metabolism on oncogenesis, tumor progression and therapeutic responses. Oncogene 32:42, pages 4995-5004.
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Galina Lurie, Lynne R. Wilkens, Yurii B. Shvetsov, Nicholas J. Ollberding, Adrian A. Franke, Brian E. Henderson, Laurence N. Kolonel & Marc T. Goodman. (2012) Prediagnostic Plasma Pyridoxal 5′-Phosphate (Vitamin B6) Levels and Invasive Breast Carcinoma Risk: The Multiethnic Cohort. Cancer Epidemiology, Biomarkers & Prevention 21:11, pages 1942-1948.
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Sang Woon Choi & Simonetta Friso. 2012. Water Soluble Vitamins. Water Soluble Vitamins 247 264 .
Halina Jurkowska, Wojciech Placha, Noriuki Nagahara & Maria Wróbel. (2010) The expression and activity of cystathionine-γ-lyase and 3-mercaptopyruvate sulfurtransferase in human neoplastic cell lines. Amino Acids 41:1, pages 151-158.
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Masashi Kuwahata. (2011) Regulatory Effect of Nutritional Status on Albumin Synthesis. Nippon Eiyo Shokuryo Gakkaishi 64:4, pages 215-219.
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Miwa NAKARI, Hiroaki KANOUCHI & Tatsuzo OKA. (2011) High Dose of Pyridoxine Induces IGFBP-3 mRNA Expression in MCF-7 Cells and Its Induction Is Inhibited by the p53-Specific Inhibitor Pifithrin-α. Journal of Nutritional Science and Vitaminology 57:4, pages 280-284.
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José S. Casas, Alfonso Castiñeiras, Félix Condori, María D. Couce, Umberto Russo, Agustín Sánchez, José Sordo, José Ma Varela & Ezequiel M. Vázquez López. (2007) Synthesis, structure and cytotoxicity of diorganotin(IV) complexes of 2,6-lutidine-α2,3-diol (Lu): The crystal structures of Lu and [SnMe2(H2O)(Lu-2H)]. Journal of Organometallic Chemistry 692:16, pages 3547-3554.
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Takahiro Masaki, Tomokazu Matsuura, Kiyoshi Ohkawa, Tatsuo Miyamura, Isao Okazaki, Tetsu Watanabe & Tetsuro Suzuki. (2006) All- trans retinoic acid down-regulates human albumin gene expression through the induction of C/EBPβ-LIP . Biochemical Journal 397:2, pages 345-353.
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Yoshiyuki Mizushina, Xianai Xu, Kiminori Matsubara, Chikako Murakami, Isoko Kuriyama, Masahiko Oshige, Masaharu Takemura, Norihisa Kato, Hiromi Yoshida & Kengo Sakaguchi. (2003) Pyridoxal 5′-phosphate is a selective inhibitor in vivo of DNA polymerase α and ε. Biochemical and Biophysical Research Communications 312:4, pages 1025-1032.
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Kiminori Matsubara, Shun-ichiro Komatsu, Tatsuzo Oka & Norihisa Kato. (2003) Vitamin B6-mediated suppression of colon tumorigenesis, cell proliferation, and angiogenesis (review). The Journal of Nutritional Biochemistry 14:5, pages 246-250.
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David C. Plais, James Gardner-Thorpe, Hiromichi Ito, Stanley W. Ashley & Edward E. Whang. (2003) Vitamin B6 inhibits the growth of human pancreatic carcinoma. Nutrition Research 23:5, pages 673-679.
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S. Komatsu, N. Yanaka, K. Matsubara & N. Kato. (2003) Antitumor effect of vitamin B6 and its mechanisms. Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics 1647:1-2, pages 127-130.
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T. Oka. (2009) Modulation of gene expression by vitamin B6. Nutrition Research Reviews 14:02, pages 257.
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Shun-ichiro Komatsu, Norihisa Kato, Hiromitsu Watanabe, Tatsuzo Oka, Haruhito Tsuge & Hironori Nii. (2001) Vitamin B-6–Supplemented Diets Compared with a Low Vitamin B-6 Diet Suppress Azoxymethane-Induced Colon Tumorigenesis in Mice by Reducing Cell Proliferation. The Journal of Nutrition 131:8, pages 2204-2207.
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Yasuo Natori, Tatsuzo Oka & Masashi Kuwahata. 2000. Biochemistry and Molecular Biology of Vitamin B6 and PQQ-dependent Proteins. Biochemistry and Molecular Biology of Vitamin B6 and PQQ-dependent Proteins 301 306 .

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