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Short Communication

The altered promoter methylation of oxytocin receptor gene in autism

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Pages 280-284 | Received 17 Dec 2015, Accepted 14 Jun 2016, Published online: 05 Aug 2016

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Andrea Stoccoro, Roberta Gallo, Sara Calderoni, Romina Cagiano, Filippo Muratori, Lucia Migliore, Enzo Grossi & Fabio Coppedè. (2022) Artificial Neural Networks Reveal Sex Differences in Gene Methylation, and Connections Between Maternal Risk Factors and Symptom Severity in Autism Spectrum Disorder. Epigenomics 14:19, pages 1181-1195.
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Roberta Gallo, Andrea Stoccoro, Romina Cagiano, Vanessa Nicolì, Rosanna Ricciardi, Raffaella Tancredi, Rosanna Trovato, Filippo Maria Santorelli, Sara Calderoni, Filippo Muratori, Lucia Migliore & Fabio Coppedè. (2022) Correlation among maternal risk factors, gene methylation and disease severity in females with autism spectrum disorder. Epigenomics 14:4, pages 175-185.
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Articles from other publishers (39)

Jelte Wieting, Kirsten Jahn, Stefan Bleich, Helge Frieling & Maximilian Deest. (2023) A targeted long-read sequencing approach questions the association of OXTR methylation with high-functioning autism. Clinical Epigenetics 15:1.
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Lane Strathearn, Allison Momany, Emese HC Kovács, William Guiler & Christine Ladd-Acosta. (2023) The intersection of genome, epigenome and social experience in autism spectrum disorder: Exploring modifiable pathways for intervention. Neurobiology of Learning and Memory 202, pages 107761.
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Andrea Stoccoro, Eugenia Conti, Elena Scaffei, Sara Calderoni, Fabio Coppedè, Lucia Migliore & Roberta Battini. (2023) DNA Methylation Biomarkers for Young Children with Idiopathic Autism Spectrum Disorder: A Systematic Review. International Journal of Molecular Sciences 24:11, pages 9138.
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Monika Lesicka, Monika Dmitrzak-Weglarz, Ewa Jablonska, Edyta Wieczorek, Pawel Kapelski, Aleksandra Szczepankiewicz, Joanna Pawlak & Edyta Reszka. (2023) Methylation of melatonin receptors in patients with unipolar and bipolar depression. Mechanisms of Ageing and Development 211, pages 111776.
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William D. Hopkins, Nicky Staes, Elaine E. Guevara, Michele M. Mulholland, Chet C. Sherwood & Brenda J. Bradley. (2023) Vasopressin, and not oxytocin, receptor gene methylation is associated with individual differences in receptive joint attention in chimpanzees ( Pan troglodytes ) . Autism Research 16:4, pages 713-722.
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Elise N. Erickson, Leslie Myatt, Joshua S. Danoff, Kathleen M. Krol & Jessica J. Connelly. (2023) Oxytocin receptor DNA methylation is associated with exogenous oxytocin needs during parturition and postpartum hemorrhage. Communications Medicine 3:1.
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Hannah M. Heseding, Kirsten Jahn, Christian K. Eberlein, Jelte Wieting, Hannah B. Maier, Phileas J. Proskynitopoulos, Alexander Glahn, Stefan Bleich, Helge Frieling & Maximilian Deest. (2022) Distinct promoter regions of the oxytocin receptor gene are hypomethylated in Prader-Willi syndrome and in Prader-Willi syndrome associated psychosis. Translational Psychiatry 12:1.
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Donatella Marazziti, Phuoc-Tan Diep, Sue Carter & Manuel Glauco Carbone. (2022) Oxytocin: An Old Hormone, a Novel Psychotropic Drug and its Possible Use in Treating Psychiatric Disorders. Current Medicinal Chemistry 29:35, pages 5615-5687.
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Asim A. Khogeer, Iman S. AboMansour & Dia A. Mohammed. (2022) The Role of Genetics, Epigenetics, and the Environment in ASD: A Mini Review. Epigenomes 6:2, pages 15.
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Leonora King, Stephanie Robins, Gary Chen, Gustavo Turecki & Phyllis Zelkowitz. 2022. Oxytocin. Oxytocin 81 103 .
Zahra Rahmani, Mohammad Reza Fayyazi Bordbar, Mohsen Dibaj, Maliheh Alimardani & Meysam Moghbeli. (2021) Genetic and molecular biology of autism spectrum disorder among Middle East population: a review. Human Genomics 15:1.
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Simeon O. A. Helgers, Svilen Angelov, Marc A. N. Muschler, Alexander Glahn, Shadi Al-Afif, Yazeed Al Krinawe, Elvis J. Hermann, Joachim K. Krauss, Helge Frieling, Kerstin Schwabe & Mathias Rhein. (2021) Epigenetic Regulation of Neural Transmission after Cerebellar Fastigial Nucleus Lesions in Juvenile Rats. The Cerebellum 20:6, pages 922-930.
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Joshua S. Danoff, Jessica J. Connelly, James P. Morris & Allison M. Perkeybile. (2021) An epigenetic rheostat of experience: DNA methylation of OXTR as a mechanism of early life allostasis. Comprehensive Psychoneuroendocrinology 8, pages 100098.
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María Victoria García-Ortiz, María José de la Torre-Aguilar, Teresa Morales-Ruiz, Antonio Gómez-Fernández, Katherine Flores-Rojas, Mercedes Gil-Campos, Pilar Martin-Borreguero, Rafael R. Ariza, Teresa Roldán-Arjona & Juan Luis Perez-Navero. (2021) Analysis of Global and Local DNA Methylation Patterns in Blood Samples of Patients With Autism Spectrum Disorder. Frontiers in Pediatrics 9.
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Janelle E. Stanton, Sigita Malijauskaite, Kieran McGourty & Andreas M. Grabrucker. (2021) The Metallome as a Link Between the “Omes” in Autism Spectrum Disorders. Frontiers in Molecular Neuroscience 14.
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Matthijs Moerkerke, Marie-Laure Bonte, Nicky Daniels, Viktoria Chubar, Kaat Alaerts, Jean Steyaert & Bart Boets. (2021) Oxytocin receptor gene (OXTR) DNA methylation is associated with autism and related social traits – A systematic review. Research in Autism Spectrum Disorders 85, pages 101785.
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Neluwa-Liyanage R. Indika, Nicolaas E.P. Deutz, Marielle P.K.J. Engelen, Hemantha Peiris, Swarna Wijetunge & Rasika Perera. (2021) Sulfur amino acid metabolism and related metabotypes of autism spectrum disorder: A review of biochemical evidence for a hypothesis. Biochimie 184, pages 143-157.
Crossref
Donald W. Pfaff. 2021. Origins of Human Socialization. Origins of Human Socialization 177 203 .
Chun Il Park, Hae Won Kim, Sumoa Jeon, Jee In Kang & Se Joo Kim. (2020) Reduced DNA methylation of the oxytocin receptor gene is associated with obsessive-compulsive disorder. Clinical Epigenetics 12:1.
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Desirée De Leon, Shota Nishitani, Hasse Walum, Kai M. McCormack, Mark E. Wilson, Alicia K. Smith, Larry J. Young & Mar M. Sanchez. (2020) Methylation of OXT and OXTR genes, central oxytocin, and social behavior in female macaques. Hormones and Behavior 126, pages 104856.
Crossref
Anna L. MacKinnon, Nancy Feeley, Ian Gold, Barbara Hayton, Leonora King, Corina Nagy, Stephanie Robins, Gustavo Turecki & Phyllis Zelkowitz. (2019) The interaction between oxytocin receptor gene methylation and maternal behavior on children's early theory of mind abilities. Development and Psychopathology 32:2, pages 511-519.
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Zongyang Lu, Zhen Liu, Wei Mao, Xinying Wang, Xiaoguo Zheng, Shanshan Chen, Beibei Cao, Shisheng Huang, Xuliang Zhang, Tao Zhou, Yu Zhang, Xingxu Huang, Qiang Sun & Jia-Da Li. (2020) Locus-specific DNA methylation of Mecp2 promoter leads to autism-like phenotypes in mice. Cell Death & Disease 11:2.
Crossref
Brandon T. Pekarek, Patrick J. Hunt & Benjamin R. Arenkiel. (2020) Oxytocin and Sensory Network Plasticity. Frontiers in Neuroscience 14.
Crossref
A.N. Chernov. (2020) Pathophysiological mechanisms of autism in children. Zhurnal nevrologii i psikhiatrii im. S.S. Korsakova 120:3, pages 97.
Crossref
Kholoud N. Bastaki, Sura Alwan & Farah R. Zahir. 2020. Personalized Food Intervention and Therapy for Autism Spectrum Disorder Management. Personalized Food Intervention and Therapy for Autism Spectrum Disorder Management 143 162 .
Donald Pfaff & Helen Barbas. (2019) Mechanisms for the Approach/Avoidance Decision Applied to Autism. Trends in Neurosciences 42:7, pages 448-457.
Crossref
Sanne Tops, Ute Habel & Sina Radke. (2019) Genetic and epigenetic regulatory mechanisms of the oxytocin receptor gene (OXTR) and the (clinical) implications for social behavior. Hormones and Behavior 108, pages 84-93.
Crossref
Kelly Glendining & Christine Jasoni. (2019) Maternal High Fat Diet-Induced Obesity Modifies Histone Binding and Expression of Oxtr in Offspring Hippocampus in a Sex-Specific Manner. International Journal of Molecular Sciences 20:2, pages 329.
Crossref
Eline J. Kraaijenvanger, Yujie He, Hannah Spencer, Alicia K. Smith, Peter A. Bos & Marco P.M. Boks. (2019) Epigenetic variability in the human oxytocin receptor (OXTR) gene: A possible pathway from early life experiences to psychopathologies. Neuroscience & Biobehavioral Reviews 96, pages 127-142.
Crossref
Aaron J. Towers, Martine W. Tremblay, Leeyup Chung, Xin-lei Li, Alexandra L. Bey, Wenhao Zhang, Xinyu Cao, Xiaoming Wang, Ping Wang, Lara J. Duffney, Stephen K. Siecinski, Sonia Xu, Yuna Kim, Xiangyin Kong, Simon Gregory, Wei Xie & Yong-hui Jiang. (2018) Epigenetic dysregulation of Oxtr in Tet1-deficient mice has implications for neuropsychiatric disorders. JCI Insight 3:23.
Crossref
Catherine Maud, Joanne Ryan, Jennifer E. McIntosh & Craig A. Olsson. (2018) The role of oxytocin receptor gene (OXTR) DNA methylation (DNAm) in human social and emotional functioning: a systematic narrative review. BMC Psychiatry 18:1.
Crossref
Jessie Poquérusse, Luigi Pastore, Sara Dellantonio & Gianluca Esposito. (2018) Alexithymia and Autism Spectrum Disorder: A Complex Relationship. Frontiers in Psychology 9.
Crossref
Zhenyu Hu, Yong Yang, Yuanzhi Zhao, Hang Yu, Xiuru Ying, Dongsheng Zhou, Jie Zhong, Zhonghua Zheng, Jing Liu, Ranran Pan, Wenwu Zhang, Fang Cheng & Shiwei Duan. (2018) APOE hypermethylation is associated with autism spectrum disorder in a Chinese population. Experimental and Therapeutic Medicine.
Crossref
Hyerim Kim, Xudong Wang & Peng Jin. (2018) Developing DNA methylation-based diagnostic biomarkers. Journal of Genetics and Genomics 45:2, pages 87-97.
Crossref
Ji-Song Guan, Hong Xie & San-Xiong Liu. (2017) Epigenetic regulators sculpt the plastic brain. Frontiers in Biology 12:5, pages 317-332.
Crossref
Silvia Ripamonti, Mateusz C Ambrozkiewicz, Francesca Guzzi, Marta Gravati, Gerardo Biella, Ingo Bormuth, Matthieu Hammer, Liam P Tuffy, Albrecht Sigler, Hiroshi Kawabe, Katsuhiko Nishimori, Mauro Toselli, Nils Brose, Marco Parenti & JeongSeop Rhee. (2017) Transient oxytocin signaling primes the development and function of excitatory hippocampal neurons. eLife 6.
Crossref
Michelle T. Siu & Rosanna Weksberg. 2017. Neuroepigenomics in Aging and Disease. Neuroepigenomics in Aging and Disease 63 90 .
Shui-Ying Tsang, Tanveer Ahmad, Flora W. K. Mat, Cunyou Zhao, Shifu Xiao, Kun Xia & Hong Xue. (2016) Variation of global DNA methylation levels with age and in autistic children. Human Genomics 10:1.
Crossref

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