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Experimental Lung Research Volume 30, 2004 - Issue 2
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Research Article

EFFICIENT DEPLETION OF ALVEOLAR MACROPHAGES USING INTRATRACHEALLY INHALED AEROSOLS OF LIPOSOME-ENCAPSULATED CLODRONATE

A. C. P. Elder Department of Environmental Medicine, University of Rochester, Rochester, New York, USACorrespondence[email protected]
,
R. Gelein Department of Environmental Medicine, University of Rochester, Rochester, New York, USA
,
G. Oberdörster Department of Environmental Medicine, University of Rochester, Rochester, New York, USA
,
J. Finkelstein Departments of Environmental Medicine and Pediatrics, University of Rochester, Rochester, New York, USA
,
R. Notter Departments of Environmental Medicine and Pediatrics, University of Rochester, Rochester, New York, USA
&
Z. Wang Department of Pediatrics, University of Rochester, Rochester, New York, USA
Pages 105-120 | Published online: 02 Jul 2009

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Read on this site (2)

Anne Van der Meeren, Agnes Moureau & Nina M. Griffiths. (2014) Macrophages as key elements of Mixed-oxide [U-Pu(O2)] distribution and pulmonary damage after inhalation?. International Journal of Radiation Biology 90:11, pages 1095-1103.
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A. Elder, C. Johnston, R. Gelein, J. Finkelstein, Z. Wang, R. Notter & G. Oberdörster. (2005) LUNG INFLAMMATION INDUCED BY ENDOTOXIN IS ENHANCED IN RATS DEPLETED OF ALVEOLAR MACROPHAGES WITH AEROSOLIZED CLODRONATE. Experimental Lung Research 31:6, pages 527-546.
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Articles from other publishers (10)

Sowbarnika Ravichandran, Nivethitha Manickam & Mahesh Kandasamy. (2022) Liposome encapsulated clodronate mediated elimination of pathogenic macrophages and microglia: A promising pharmacological regime to defuse cytokine storm in COVID-19. Medicine in Drug Discovery 15, pages 100136.
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Lu Wang, Huasheng Zhang, Liya Sun, Wei Gao, Ye Xiong, Aying Ma, Xiali Liu, Lei Shen, Qiang Li & Hong Yang. (2020) Manipulation of macrophage polarization by peptide-coated gold nanoparticles and its protective effects on acute lung injury. Journal of Nanobiotechnology 18:1.
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Debra L. LaskinVasanthi R. SunilCarol R. GardnerJeffrey D. Laskin. (2011) Macrophages and Tissue Injury: Agents of Defense or Destruction?. Annual Review of Pharmacology and Toxicology 51:1, pages 267-288.
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Bo-Ram BangEunyoung ChunEun-Jin ShimHyun-Seung LeeSoo-Yeon LeeSang-Heon ChoKyung-Up MinYou-Young KimHeung-Woo Park. (2011) Alveolar macrophages modulate allergic inflammation in a murine model of asthma. Experimental and Molecular Medicine 43:5, pages 275.
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Sandra Lo Re, Laure Dumoutier, Isabelle Couillin, Charlotte Van Vyve, Yousof Yakoub, Francine Uwambayinema, Benoît Marien, Sybille van den Brûle, Jacques Van Snick, Catherine Uyttenhove, Bernard Ryffel, Jean-Christophe Renauld, Dominique Lison & François Huaux. (2010) IL-17A–Producing γδ T and Th17 Lymphocytes Mediate Lung Inflammation but Not Fibrosis in Experimental Silicosis. The Journal of Immunology 184:11, pages 6367-6377.
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David Y. Lai & Philip G. Sayre. 2009. Nanotoxicity. Nanotoxicity 427 457 .
D van Berlo, C Albrecht, A M Knaapen, F J van Schooten & R P F Schins. (2009) The role of macrophage mediators in respirable quartz-elicited inflammation. Journal of Physics: Conference Series 151, pages 012046.
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Chiming Wei, Wenchi Wei, Michael Morris, Eisaku Kondo, Mikhail Gorbounov & Donald A. Tomalia. (2007) Nanomedicine and Drug Delivery. Medical Clinics of North America 91:5, pages 863-870.
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Minqing Zhao, Lucas G. Fernandez, Allan Doctor, Ashish K. Sharma, Alexander Zarbock, Curtis G. Tribble, Irving L. Kron & Victor E. Laubach. (2006) Alveolar macrophage activation is a key initiation signal for acute lung ischemia-reperfusion injury. American Journal of Physiology-Lung Cellular and Molecular Physiology 291:5, pages L1018-L1026.
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Peiyong Li, Zhonghua Tan, Yihua Zhu, Suyun Chen, Shuli Ding & Hongming Zhuang. (2006) Targeting study of gelatin adsorbed clodronate in reticuloendothelial system and its potential application in immune thrombocytopenic purpura of rat model. Journal of Controlled Release 114:2, pages 202-208.
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