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Experimental Lung Research Volume 45, 2019 - Issue 5-6
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Original Article

Schisandrin B inhibits TGF-β1-induced epithelial-mesenchymal transition in human A549 cells through epigenetic silencing of ZEB1

Wenyue ZhuangDepartment of Molecular Biology Test Technique, College of Medical Technology, Beihua University, Jilin, China; View further author information
,
Zhengyi LiDepartment of Clinical Examination Basis, Laboratory Academy, Jilin Medical College, Jilin, China; View further author information
,
Xiaoman DongDepartment of Molecular Biology Test Technique, College of Medical Technology, Beihua University, Jilin, China; View further author information
,
Na ZhaoDepartment of Molecular Biology Test Technique, College of Medical Technology, Beihua University, Jilin, China; View further author information
,
Yan LiuDepartment of Molecular Biology Test Technique, College of Medical Technology, Beihua University, Jilin, China; View further author information
,
Chunmei WangDepartment of Pharmacology, College of Pharmacy, Beihua University, Jilin, ChinaCorrespondence[email protected]
View further author information
&
Jianguang ChenDepartment of Pharmacology, College of Pharmacy, Beihua University, Jilin, ChinaCorrespondence[email protected]
View further author information
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Pages 157-166 | Received 10 Nov 2018, Accepted 06 Jun 2019, Published online: 03 Jul 2019

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Hasan Badibostan, Nastaran Eizadi-Mood, A. Wallace Hayes & Gholamreza Karimi. (2024) Protective effects of natural compounds against paraquat-induced pulmonary toxicity: the role of the Nrf2/ARE signaling pathway. International Journal of Environmental Health Research 34:1, pages 611-624.
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Articles from other publishers (17)

Margherita Sisto & Sabrina Lisi. (2024) Epigenetic Regulation of EMP/EMT-Dependent Fibrosis. International Journal of Molecular Sciences 25:5, pages 2775.
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Jiajun Pan, Yichen Jiang, Yuanyuan Huang, Haiying Zhang, Xi Wang, Chao Luo, Hui Wang, Miao Tang, Gang Pei & Qun Tang. (2023) Liuwei Dihuang Decoction Drug-containing Serum Attenuates Transforming Growth Factor-β1-induced Epithelial-mesenchymal Transition in HK-2 Cells by Inhibiting NF-κB/Snail Signaling Pathway. Current Pharmaceutical Biotechnology 24:12, pages 1589-1602.
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Xian-Chen Wang, Kai Song, Bin Tu, He Sun, Yang Zhou, Sheng-Song Xu, Dong Lu, Ji-Ming Sha & Hui Tao. (2023) New aspects of the epigenetic regulation of EMT related to pulmonary fibrosis. European Journal of Pharmacology 956, pages 175959.
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Liqin Zhou, Liping Zhou, Huanjie Ma, Jinkai Zhao & Dayong Lou. (2023) Schisandrin B Inhibits Osteosarcoma Cell Proliferation and Promotes Apoptosis Through PI3K/AKT/mTOR Pathway Mediated Autophagy. Revista Brasileira de Farmacognosia 33:5, pages 945-953.
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TIANZHU LI, YU ZHANG, TONG ZHANG, YANNAN LI, HUI XUE, JINGLONG CAO, WENSHUANG HOU, YINGHUA LUO & CHENGHAO JIN. (2023) Schisandrin B exerts anticancer effects on human gastric cancer cells through ROS-mediated MAPK, STAT3, and NF-κB pathways. BIOCELL 47:1, pages 195-204.
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Miso Park, Keon Wook Kang & Ji Won Kim. (2023) The role and application of transcriptional repressors in cancer treatment. Archives of Pharmacal Research 46:1, pages 1-17.
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Zhenghua Wu, Mengqi Jia, Wenjuan Zhao, Xucong Huang, Xinyi Yang, Dongxin Chen, Xijier Qiaolongbatu, Xiaojing Li, Jiaqi Wu, Feng Qian, Yuefen Lou & Guorong Fan. (2022) Schisandrol A, the main active ingredient of Schisandrae Chinensis Fructus, inhibits pulmonary fibrosis through suppression of the TGF-β signaling pathway as revealed by UPLC-Q-TOF/MS, network pharmacology and experimental verification. Journal of Ethnopharmacology 289, pages 115031.
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Mingwei Zhu, Jiamei Niu, Jian Jiang, Tianxiu Dong, Yaodong Chen, Xiuhua Yang & Pengfei Liu. (2022) Chelerythrine inhibits the progression of glioblastoma by suppressing the TGFB1-ERK1/2/Smad2/3-Snail/ZEB1 signaling pathway. Life Sciences 293, pages 120358.
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Varalakshmi Velagacherla, Chetan Hasmukh Mehta, Yogendra Nayak & Usha Yogendra Nayak. (2022) Molecular pathways and role of epigenetics in the idiopathic pulmonary fibrosis. Life Sciences 291, pages 120283.
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Mingjie Wang, Yan Sun, Cheng Li, Jing Qu & Bing Zhou. (2022) Eosinophils Correlate with Epithelial-Mesenchymal Transition in Chronic Rhinosinusitis with Nasal Polyps. ORL 84:1, pages 70-80.
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Tiantian Liu, Pengli Xu, Shaorui Ke, Haoran Dong, Mengmeng Zhan, Qin Hu & Jiansheng Li. (2022) Histone methyltransferase SETDB1 inhibits TGF-β-induced epithelial–mesenchymal transition in pulmonary fibrosis by regulating SNAI1 expression and the ferroptosis signaling pathway. Archives of Biochemistry and Biophysics 715, pages 109087.
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Syeda Saniya Zahra, Ihsan-ul Haq & Omer Farooq. 2022. Nutraceuticals and Health Care. Nutraceuticals and Health Care 61 85 .
Tihong Shao, Xiaodong Shi, Shanpeng Yang, Wei Zhang, Xiaohu Li, Jingwei Shu, Shehabaldin Alqalyoobi, Amir A. Zeki, Patrick S. Leung & Zongwen Shuai. (2021) Interstitial Lung Disease in Connective Tissue Disease: A Common Lesion With Heterogeneous Mechanisms and Treatment Considerations. Frontiers in Immunology 12.
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Krystian Bartczak, Adam J. Białas, Mateusz J. Kotecki, Paweł Górski & Wojciech J. Piotrowski. (2020) More than a Genetic Code: Epigenetics of Lung Fibrosis. Molecular Diagnosis & Therapy 24:6, pages 665-681.
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Kamil Kiełbasiński, Wojciech Peszek, Beniamin O. Grabarek, Dariusz Boroń, Magdalena Wierzbik-Strońska & Marcin Oplawski. (2020) Effect of Salinomycin on Expression Pattern of Genes Associated with Apoptosis in Endometrial Cancer Cell Line. Current Pharmaceutical Biotechnology 21:12, pages 1269-1277.
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Milad Ashrafizadeh, Hui Li Ang, Ebrahim Rahmani Moghadam, Shima Mohammadi, Vahideh Zarrin, Kiavash Hushmandi, Saeed Samarghandian, Ali Zarrabi, Masoud Najafi, Reza Mohammadinejad & Alan Prem Kumar. (2020) MicroRNAs and Their Influence on the ZEB Family: Mechanistic Aspects and Therapeutic Applications in Cancer Therapy. Biomolecules 10:7, pages 1040.
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Andy Wai Kan Yeung, Nikolay T. Tzvetkov, Aneliya A. Balacheva, Maya G. Georgieva, Ren-You Gan, Artur Jozwik, Bożena Pyzel, Jarosław O. Horbańczuk, Ettore Novellino, Alessandra Durazzo, Massimo Lucarini, Emanuela Camilli, Eliana B. Souto, Atanas G. Atanasov & Antonello Santini. (2020) Lignans: Quantitative Analysis of the Research Literature. Frontiers in Pharmacology 11.
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