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Experimental Lung Research Volume 45, 2019 - Issue 7
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Original Articles

The novel inhibitor PRI-724 for Wnt/β-catenin/CBP signaling ameliorates bleomycin-induced pulmonary fibrosis in mice

Hiroyasu OkazakiDepartment of Respiratory Medicine and Rheumatology, Graduate School of Biomedical Sciences, Tokushima University, Tokushima, Japan; View further author information
,
Seidai SatoDepartment of Respiratory Medicine and Rheumatology, Graduate School of Biomedical Sciences, Tokushima University, Tokushima, Japan; View further author information
,
Kazuya KoyamaDepartment of Respiratory Medicine and Rheumatology, Graduate School of Biomedical Sciences, Tokushima University, Tokushima, Japan; View further author information
,
Shun MorizumiDepartment of Respiratory Medicine and Rheumatology, Graduate School of Biomedical Sciences, Tokushima University, Tokushima, Japan; View further author information
,
Shuichi AbeDepartment of Respiratory Medicine and Rheumatology, Graduate School of Biomedical Sciences, Tokushima University, Tokushima, Japan; View further author information
,
Momoyo AzumaDepartment of Respiratory Medicine and Rheumatology, Graduate School of Biomedical Sciences, Tokushima University, Tokushima, Japan; View further author information
,
Yajuan ChenDepartment of Respiratory Medicine and Rheumatology, Graduate School of Biomedical Sciences, Tokushima University, Tokushima, Japan; View further author information
,
Hisatsugu GotoDepartment of Respiratory Medicine and Rheumatology, Graduate School of Biomedical Sciences, Tokushima University, Tokushima, Japan; View further author information
,
Yoshinori AonoDepartment of Respiratory Medicine and Rheumatology, Graduate School of Biomedical Sciences, Tokushima University, Tokushima, Japan; ;National Hospital Organization Higashi Tokushima Medical Center, Tokushima, Japan; View further author information
,
Hirohisa OgawaDepartment of Pathology and Laboratory Medicine, Tokushima University Graduate School, Tokushima, Japan; View further author information
,
Kozo KagawaDepartment of Respiratory Medicine and Rheumatology, Graduate School of Biomedical Sciences, Tokushima University, Tokushima, Japan; View further author information
,
Haruka NishimuraDepartment of Respiratory Medicine and Rheumatology, Graduate School of Biomedical Sciences, Tokushima University, Tokushima, Japan; View further author information
,
Hiroshi KawanoDepartment of Respiratory Medicine and Rheumatology, Graduate School of Biomedical Sciences, Tokushima University, Tokushima, Japan; View further author information
,
Yuko ToyodaDepartment of Respiratory Medicine and Rheumatology, Graduate School of Biomedical Sciences, Tokushima University, Tokushima, Japan; View further author information
,
Hisanori UeharaDepartment of Pathology and Laboratory Medicine, Tokushima University Graduate School, Tokushima, Japan; View further author information
,
Hiroyuki KoujiPRISM BioLab Co., Ltd., Midori-ku, Yokohama, Japan; ;Faculty of Medicine, Oita University, Yufu-city, Oita, JapanView further author information
&
Yasuhiko NishiokaDepartment of Respiratory Medicine and Rheumatology, Graduate School of Biomedical Sciences, Tokushima University, Tokushima, Japan; Correspondence[email protected]
View further author information
 show all
Pages 188-199 | Received 16 Jan 2019, Accepted 27 Jun 2019, Published online: 12 Jul 2019

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Yucong Li, Dong Wang, Jingshu Liu, Yunzhe Li, Duke Chen, Lei Zhou, Tingyuan Lang & Qi Zhou. (2020) Baicalin Attenuates YAP Activity to Suppress Ovarian Cancer Stemness. OncoTargets and Therapy 13, pages 7151-7163.
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Ronggui Liu, Qinqin Wang, Zhaoyan Ding, Xiaojuan Zhang, Yunping Li, Yichen Zang & Guijun Zhang. (2020) Silibinin Augments the Antifibrotic Effect of Valsartan Through Inactivation of TGF-β1 Signaling in Kidney. Drug Design, Development and Therapy 14, pages 603-611.
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Kyung Hwa Choi, Dae Keun Kim, A Ram Kim & Seung‐Ryeol Lee. (2022) Prevention of urethral fibrosis induced by transforming growth factor beta 1 using selective Wnt/β‐catenin signaling inhibitors in a rat model. International Journal of Urology 29:7, pages 764-771.
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Chengli Liu, Shanshan Sun, Jie Xie, Hui Li, Tianyu Li, Qiqi Wu, Yongsheng Zhang, Xiangjun Bai, Jian Wang, Xin Wang, Zhanfei Li & Wei Wang. (2022) GLP-1R Agonist Exendin-4 Protects Against Hemorrhagic Transformation Induced by rtPA After Ischemic Stroke via the Wnt/β-Catenin Signaling Pathway. Molecular Neurobiology 59:6, pages 3649-3664.
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Qi Wang, Song Wei, Lei Li, Qingfa Bu, Haoming Zhou, Wantong Su, Zheng Liu, Mingming Wang & Ling Lu. (2021) miR-139-5p sponged by LncRNA NEAT1 regulates liver fibrosis via targeting β-catenin/SOX9/TGF-β1 pathway. Cell Death Discovery 7:1.
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Amit Kishore & Martin Petrek. (2021) Roles of Macrophage Polarization and Macrophage-Derived miRNAs in Pulmonary Fibrosis. Frontiers in Immunology 12.
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Michael Latour, Nam-Gu Her, Santosh Kesari & Elmar Nurmemmedov. (2021) WNT Signaling as a Therapeutic Target for Glioblastoma. International Journal of Molecular Sciences 22:16, pages 8428.
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Michal Caspi, Amnon Wittenstein, Michal Kazelnik, Yarden Shor-Nareznoy & Rina Rosin-Arbesfeld. (2021) Therapeutic targeting of the oncogenic Wnt signaling pathway for treating colorectal cancer and other colonic disorders. Advanced Drug Delivery Reviews 169, pages 118-136.
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Keane K. Y. Lai & Michael Kahn. 2021. Pharmacology of the WNT Signaling System. Pharmacology of the WNT Signaling System 383 422 .
Alexandra McMellen, Elizabeth R. Woodruff, Bradley R. Corr, Benjamin G. Bitler & Marisa R. Moroney. (2020) Wnt Signaling in Gynecologic Malignancies. International Journal of Molecular Sciences 21:12, pages 4272.
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Philip Chiu-Tsun Tang, Ying-Ying Zhang, Max Kam-Kwan Chan, Winson Wing-Yin Lam, Jeff Yat-Fai Chung, Wei Kang, Ka-Fai To, Hui-Yao Lan & Patrick Ming-Kuen Tang. (2020) The Emerging Role of Innate Immunity in Chronic Kidney Diseases. International Journal of Molecular Sciences 21:11, pages 4018.
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