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Experimental Lung Research Volume 31, 2005 - Issue 6
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AMORPHOUS SILICA PARTICLES PROMOTE INFLAMMATORY GENE EXPRESSION THROUGH THE REDOX SENSITIVE TRANSCRIPTION FACTOR, AP-1, IN ALVEOLAR EPITHELIAL CELLS

Madhuri Singal Department of Environmental Medicine, School of Medicine and Dentistry, The University of Rochester, Rochester New York, USA
&
Jacob N. Finkelstein Departments of Environmental Medicine and Pediatrics, School of Medicine and Dentistry The University of Rochester, Rochester New York, USA
Pages 581-597 | Received 28 Oct 2004, Accepted 01 Mar 2005, Published online: 02 Jul 2009

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Madhuri Singal & Jacob N. Finkelstein. (2005) Use of Indicator Cell Lines for Determining Inflammatory Gene Changes and Screening the Inflammatory Potential of Particulate and Non-Particulate Stimuli. Inhalation Toxicology 17:9, pages 415-425.
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Articles from other publishers (16)

Vanessa Marques Da Silva, Manon Benjdir, Pierrick Montagne, Jean-Claude Pairon, Sophie Lanone & Pascal Andujar. (2022) Pulmonary Toxicity of Silica Linked to Its Micro- or Nanometric Particle Size and Crystal Structure: A Review. Nanomaterials 12:14, pages 2392.
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Yuan Cheng, Xue-lei Ma, Yu-quan Wei & Xia-Wei Wei. (2019) Potential roles and targeted therapy of the CXCLs/CXCR2 axis in cancer and inflammatory diseases. Biochimica et Biophysica Acta (BBA) - Reviews on Cancer 1871:2, pages 289-312.
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Mostafa Yazdimamaghani, Philip J. Moos, Marina A. Dobrovolskaia & Hamidreza Ghandehari. (2019) Genotoxicity of amorphous silica nanoparticles: Status and prospects. Nanomedicine: Nanotechnology, Biology and Medicine 16, pages 106-125.
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Ayushi Priyam, Pushplata Prasad Singh & Shweta Gehlout. (2018) Role of Endocrine-Disrupting Engineered Nanomaterials in the Pathogenesis of Type 2 Diabetes Mellitus. Frontiers in Endocrinology 9.
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Gayatri Premshekharan, Kennedy Nguyen, Hongqiao Zhang, Henry Jay Forman & Valerie Jean Leppert. (2017) Low dose inflammatory potential of silica particles in human-derived THP-1 macrophage cell culture studies – Mechanism and effects of particle size and iron. Chemico-Biological Interactions 272, pages 160-171.
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Horacio Bach. 2015. Bio-Nanoparticles. Bio-Nanoparticles 273 302 .
Madhuri Singal. 2015. Comparative Biology of the Normal Lung. Comparative Biology of the Normal Lung 601 627 .
Joanna McCarthy, Iwona Inkielewicz-Stępniak, J. Jose Corbalan & Marek W. Radomski. (2012) Mechanisms of Toxicity of Amorphous Silica Nanoparticles on Human Lung Submucosal Cells in Vitro: Protective Effects of Fisetin. Chemical Research in Toxicology 25:10, pages 2227-2235.
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Tobias Müller, Christian Schumann & Annette Kraegeloh. (2012) STED Microscopy and its Applications: New Insights into Cellular Processes on the Nanoscale. ChemPhysChem 13:8, pages 1986-2000.
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Claudia Fruijtier-Pölloth. (2012) The toxicological mode of action and the safety of synthetic amorphous silica—A nanostructured material. Toxicology 294:2-3, pages 61-79.
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Laurel E. Plummer, Kent E. Pinkerton, Amy K. Madl & Dennis W. Wilson. 2011. Cardiovascular Effects of Inhaled Ultrafine and Nanosized Particles. Cardiovascular Effects of Inhaled Ultrafine and Nanosized Particles 317 350 .
Sabrina Schübbe, Christian Cavelius, Christian Schumann, Marcus Koch & Annette Kraegeloh. (2010) STED Microscopy to Monitor Agglomeration of Silica Particles Inside A549 Cells. Advanced Engineering Materials 12:5, pages 417-422.
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Galya Orr, David J. Panther, Kaylyn J. Cassens, Jaclyn L. Phillips, Barbara J. Tarasevich & Joel G. Pounds. (2009) Syndecan-1 mediates the coupling of positively charged submicrometer amorphous silica particles with actin filaments across the alveolar epithelial cell membrane. Toxicology and Applied Pharmacology 236:2, pages 210-220.
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Cristina Buzea, Ivan I. Pacheco & Kevin Robbie. (2007) Nanomaterials and nanoparticles: Sources and toxicity. Biointerphases 2:4, pages MR17-MR71.
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Galya Orr, David J. Panther, Jaclyn L. Phillips, Barbara J. Tarasevich, Alice Dohnalkova, Dehong Hu, Justin G. Teeguarden & Joel G. Pounds. (2007) Submicrometer and Nanoscale Inorganic Particles Exploit the Actin Machinery To Be Propelled along Microvilli-like Structures into Alveolar Cells. ACS Nano 1:5, pages 463-475.
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Jared M. Brown, Emily J. Swindle, Nataliya M. Kushnir-Sukhov, Andrij Holian & Dean D. Metcalfe. (2007) Silica-Directed Mast Cell Activation Is Enhanced by Scavenger Receptors. American Journal of Respiratory Cell and Molecular Biology 36:1, pages 43-52.
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