Publication Cover
Comments on Inorganic Chemistry
A Journal of Critical Discussion of the Current Literature
Volume 16, 1994 - Issue 1-2
118
Views
44
CrossRef citations to date
0
Altmetric
Original Articles

The Role of Metals in the Hydrolytic Cleavage of DNA and RNA

&
Pages 77-93 | Received 18 Oct 1993, Published online: 23 Sep 2006

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (2)

William C. Putnam & James K. Bashkin. (2005) Synthesis and Evaluation of RNA Transesterification Efficiency Using Stereospecific Serinol-Terpyridine Conjugates. Nucleosides, Nucleotides & Nucleic Acids 24:9, pages 1309-1323.
Read now

Articles from other publishers (42)

Lisa Bornewasser, Christof Domnick & Stephanie Kath-Schorr. (2022) Stronger together for in-cell translation: natural and unnatural base modified mRNA. Chemical Science 13:17, pages 4753-4761.
Crossref
Shagufta Haque, Sanchita Tripathy & Chitta Ranjan Patra. (2021) Manganese-based advanced nanoparticles for biomedical applications: future opportunity and challenges. Nanoscale 13:39, pages 16405-16426.
Crossref
Samuel A. Juliano, Leonardo F. Serafim, Searle S. Duay, Maria Heredia Chavez, Gaurav Sharma, Mary Rooney, Fatih Comert, Scott Pierce, Andrei Radulescu, Myriam L. Cotten, Mihaela Mihailescu, Eric R. May, Alexander I. Greenwood, Rajeev Prabhakar & Alfredo M. Angeles-Boza. (2020) A Potent Host Defense Peptide Triggers DNA Damage and Is Active against Multidrug-Resistant Gram-Negative Pathogens. ACS Infectious Diseases 6:5, pages 1250-1263.
Crossref
Kristian Le Vay, Elia Salibi, Emilie Y. Song & Hannes Mutschler. (2019) Nucleic Acid Catalysis under Potential Prebiotic Conditions. Chemistry – An Asian Journal 15:2, pages 214-230.
Crossref
Qiaoyu Hu, Vindi M. Jayasinghe-Arachchige, Joshua Zuchniarz & Rajeev Prabhakar. (2019) Effects of the Metal Ion on the Mechanism of Phosphodiester Hydrolysis Catalyzed by Metal-Cyclen Complexes. Frontiers in Chemistry 7.
Crossref
Ruchi Gaur & Lallan Mishra. (2013) Bi-nuclear Ru(ii) complexes of bis-chalcone and bis-flavonol: synthesis, characterization, photo cleavage of DNA and Topoisomerase I inhibition. RSC Advances 3:30, pages 12210.
Crossref
Niraj Kumari, Brajesh Kumar Maurya, Raj Kumar Koiri, Surendra Kumar Trigun, Srikrishna Saripella, Michael P. Coogan & Lallan Mishra. (2011) Cytotoxic activity, cell imaging and photocleavage of DNA induced by a Pt(ii) cyclophane bearing 1,2 diamino ethane as a terminal ligand. MedChemComm 2:12, pages 1208.
Crossref
Wanda Radecka-Paryzek. (2009) Self-assembly in Schiff base lanthanide complexes — From supramolecular dimers to coordination polymers. Canadian Journal of Chemistry 87:1, pages 1-7.
Crossref
Ashu Chaudhary & R.V. Singh. (2008) Review: Metal Complexes of Polyaza and Polyoxaaza Macrocyclic Ligands: A Look into the Past and Present Work. Reviews in Inorganic Chemistry 28:1.
Crossref
Wanda Radecka-Paryzek, Violetta Patroniak & Jerzy Lisowski. (2005) Metal complexes of polyaza and polyoxaaza Schiff base macrocycles. Coordination Chemistry Reviews 249:21-22, pages 2156-2175.
Crossref
M. Lainé, F. Richard, E. Tarnaud, C. Bied-Charreton & C. Verchère-Béaur. (2004) Synthesis of novel types of copper-bipyridyl porphyrins and characterization of their interactions and reactivity with DNA. JBIC Journal of Biological Inorganic Chemistry 9:5, pages 550-562.
Crossref
S. Verma, S. G. Srivatsan & C. Madhavaiah. 2004. Artificial Nucleases. Artificial Nucleases 129 150 .
A. Dallas, A. V. Vlassov & S. A. Kazakov. 2004. Artificial Nucleases. Artificial Nucleases 61 88 .
Ramaswamy Murugavel, Malaichamy Sathiyendiran, Ramasamy Pothiraja & Ray J. Butcher. (2003) O–H Bond elongation in co-ordinated water through intramolecular PO⋯H–O bonding. ‘Snap-shots’ in phosphate ester hydrolysis. Chem. Commun.:20, pages 2546-2547.
Crossref
Jian Gao, Arthur E Martell & Joseph Reibenspies. (2002) Novel Cu(II)Cd(II) macrocyclic complex that hydrolyzes an activated phosphate diester. Inorganica Chimica Acta 329:1, pages 122-128.
Crossref
Paul E. Jurek & Arthur E. Martell. (1999) Molecular Recognition of Activated and Unactivated Phosphate Diesters. Inorganic Chemistry 38:26, pages 6003-6007.
Crossref
James K Bashkin. (1999) Hydrolysis of phosphates, esters and related substrates by models of biological catalysts. Current Opinion in Chemical Biology 3:6, pages 752-758.
Crossref
Lisa A. Jenkins, James K. Bashkin, Jennifer D. Pennock, Jan Florián & Arieh Warshel. (1999) Catalytic Hydrolysis of Adenosine 2‘,3‘-Cyclic Monophosphate by Cu II Terpyridine . Inorganic Chemistry 38:13, pages 3215-3222.
Crossref
Andrei Blaskó & Thomas C. Bruice. (1999) Recent Studies of Nucleophilic, General-Acid, and Metal Ion Catalysis of Phosphate Diester Hydrolysis. Accounts of Chemical Research 32:6, pages 475-484.
Crossref
Louis Y. Kuo & Laurie A. Barnes. (1999) Aqueous Phosphoester Bond Cleavage of Dimethyl Phosphate by Cp 2 MoCl 2 :  First Reported Case of Hydrolytic Cleavage on an Unactivated Phosphate Diester by an Organometallic Complex . Inorganic Chemistry 38:4, pages 814-817.
Crossref
Masaki Warashina, De-Min Zhou, Tomoko Kuwabara & Kazunari Taira. 1999. Comprehensive Natural Products Chemistry. Comprehensive Natural Products Chemistry 235 268 .
Timothy M. Glennon & Arieh Warshel. (1998) Energetics of the Catalytic Reaction of Ribonuclease A: A Computational Study of Alternative Mechanisms. Journal of the American Chemical Society 120:39, pages 10234-10247.
Crossref
I. Zagorowska, S. Kuusela & H. Lonnberg. (1998) Metal ion-dependent hydrolysis of RNA phosphodiester bonds within hairpin loops. A comparative kinetic study on chimeric ribo/2'-O-methylribo oligonucleotides. Nucleic Acids Research 26:14, pages 3392-3396.
Crossref
De-Min Zhou & Kazunari Taira. (1998) The Hydrolysis of RNA:  From Theoretical Calculations to the Hammerhead Ribozyme-Mediated Cleavage of RNA. Chemical Reviews 98:3, pages 991-1026.
Crossref
Robert G. Kuimelis & Larry W. McLaughlin. (1998) Mechanisms of Ribozyme-Mediated RNA Cleavage. Chemical Reviews 98:3, pages 1027-1044.
Crossref
Bobby N. Trawick, Andrew T. Daniher & James K. Bashkin. (1998) Inorganic Mimics of Ribonucleases and Ribozymes:  From Random Cleavage to Sequence-Specific Chemistry to Catalytic Antisense Drugs. Chemical Reviews 98:3, pages 939-960.
Crossref
Anne Roigk, Ronald Hettich & Hans-Jörg Schneider. (1998) Unusual Catalyst Concentration Effects in the Hydrolysis of Phenyl Phosphate Esters and of DNA:  A Systematic Investigation of the Lanthanide Series 1 . Inorganic Chemistry 37:4, pages 751-756.
Crossref
Geneviève Pratviel, Jean Bernadou & Bernard Meunier. 1998. 251 312 .
Vishnu J Ram & Atul Goel. (1997) Synthesis of Dipyridinyls and Terpyridinyls with Phenyl Spacers through Base Induced Ring Transformation Reactions. Chemistry Letters 26:10, pages 1021-1022.
Crossref
Lisa A. Jenkins Autry & James K. Bashkin. (1997) Transesterification of RNA by Cu(II) terpyridine. Inorganica Chimica Acta 263:1-2, pages 49-52.
Crossref
Robert G. Kuimelis & Larry W. McLaughlin. (1997) Application of a 5′-bridging phosphorothioate to probe divalent metal and hammerhead ribozyme mediated RNA cleavage. Bioorganic & Medicinal Chemistry 5:6, pages 1051-1061.
Crossref
James K Bashkin. (1997) DNA enzymes: New-found chemical reactivity. Current Biology 7:5, pages R286-R288.
Crossref
Eric L. Hegg, Kim A. Deal, Laura L. Kiessling & Judith N. Burstyn. (1997) Hydrolysis of Double-Stranded and Single-Stranded RNA in Hairpin Structures by the Copper(II) Macrocycle Cu([9]aneN 3 )Cl 2 . Inorganic Chemistry 36:8, pages 1715-1718.
Crossref
Satu Kuusela, Andrei Guzaev & Harri Lönnberg. (1996) Acceleration of the Zn 2+ -promoted phosphodiester hydrolysis of oligonucleotides by the 3′-terminal monophosphate group: intrastrand participation over several nucleoside units . J. Chem. Soc., Perkin Trans. 2:9, pages 1895-1899.
Crossref
James K. Bashkin, Jin Xie, Andrew T. Daniher, UmaShanker Sampath & Jeffrey L.-F. Kao. (1996) Building Blocks for Ribozyme Mimics:  Conjugates of Terpyridine and Bipyridine with Nucleosides. The Journal of Organic Chemistry 61:7, pages 2314-2321.
Crossref
Thomas C. Bruice, Akira Tsubouchi, Robert O. Dempcy & Leif P. Olson. (1996) One- and Two-Metal Ion Catalysis of the Hydrolysis of Adenosine 3‘-Alkyl Phosphate Esters. Models for One- and Two-Metal Ion Catalysis of RNA Hydrolysis. Journal of the American Chemical Society 118:41, pages 9867-9875.
Crossref
Lisa A. Jenkins, James K. Bashkin & Mark E. Autry. (1996) The Embedded Ribonucleotide Assay:  A Chimeric Substrate for Studying Cleavage of RNA by Transesterification. Journal of the American Chemical Society 118:29, pages 6822-6825.
Crossref
George C. Yeh, Alicia M. Beatty & James K. Bashkin. (1996) Synthesis and Characterization of Cobalt-Cage Complexes with Pendant Phenol Groups. Inorganic Chemistry 35:13, pages 3828-3835.
Crossref
Soon Jin Oh, Kyong Hwa Song, Dongmok Whang, Kimoon Kim, Tae Hyun Yoon, Hichung Moon & Joon Won Park. (1996) Catalytic Hydrolysis of Phosphate Diesters by Lanthanide(III) Cryptate (2.2.1) Complexes. Inorganic Chemistry 35:13, pages 3780-3785.
Crossref
James K. Bashkin, Jin Xie, Andrew T. Daniher, Lisa A. Jenkins & George C. Yeh. 1996. DNA and RNA Cleavers and Chemotherapy of Cancer and Viral Diseases. DNA and RNA Cleavers and Chemotherapy of Cancer and Viral Diseases 355 366 .
R. G. Kuimelis & L. W. McLaughlin. 1996. Catalytic RNA. Catalytic RNA 197 215 .
James K. Bashkin, Umashanker Sampath & Elena Frolova. (1995) Ribozyme mimics as catalytic antisense reagents. Applied Biochemistry and Biotechnology 54:1-3, pages 43-56.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.