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Original Articles

Extreme exercise and oxidative DNA modification

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Pages 343-346 | Accepted 15 Mar 1996, Published online: 15 May 2007

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Ricardo Aparecido Baptista Nucci, Ana Caroline de Souza Teodoro, Walter Krause Neto, Wellington de Assis Silva, Romeu Rodrigues de Souza, Carlos Alberto Anaruma & Eliane Florencio Gama. (2018) Effects of resistance training on liver structure and function of aged rats. The Aging Male 21:1, pages 60-64.
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Pernille K. Ellegaard & Henrik E. Poulsen. (2016) Tobacco smoking and oxidative stress to DNA: a meta-analysis of studies using chromatographic and immunological methods. Scandinavian Journal of Clinical and Laboratory Investigation 76:2, pages 151-158.
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D. Villaño, C. Vilaplana, S. Medina, R. Cejuela-Anta, J. M. Martínez-Sanz, P. Gil, H.-G. Genieser, F. Ferreres & A. Gil-Izquierdo. (2015) Effect of elite physical exercise by triathletes on seven catabolites of DNA oxidation. Free Radical Research 49:8, pages 973-983.
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GlenE. Kisby, JuanF. Muniz, Jennifer Scherer, MichaelR. Lasarev, Mary Koshy, YokeW. Kow & Linda McCauley. (2009) Oxidative Stress and DNA Damage in Agricultural Workers. Journal of Agromedicine 14:2, pages 206-214.
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Domenico Fusco, Giuseppe Colloca, Maria Rita Lo Monaco & Matteo Cesari. (2007) Effects of antioxidant supplementation on the aging process. Clinical Interventions in Aging 2:3, pages 377-387.
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Jefferey L. Burgess, María M. Meza, Arun B. Josyula, Gerald S. Poplin, Michael J. Kopplin, Hannah E. McClellen, Stefan Stürup & R. Clark Lantz. (2007) Environmental Arsenic Exposure and Urinary 8-OHdG in Arizona and Sonora. Clinical Toxicology 45:5, pages 490-498.
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Jefferey L. Burgess, Joy E. Fleming, Emmanuel M. Mulenga, Arun Josyula, Tracy A. Hysong, Philip J. Joggerst, Margaret Kurzius-Spencer & Hugh B. Miller. (2007) Acute changes in sputum IL-10 following underground exposure to diesel exhaust. Clinical Toxicology 45:3, pages 255-260.
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Tomi-Pekka Tuomainen, Steffen Loft, Kristiina Nyyssönen, Kari Punnonen, Jukka T. Salonen & Henrik E. Poulsen. (2007) Body iron is a contributor to oxidative damage of DNA. Free Radical Research 41:3, pages 324-328.
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Sampath Parthasarathy, Nalini Santanam, Sumathi Ramachandran & Olivier Meilhac. (2000) Potential role of oxidized lipids and lipoproteins in antioxidant defense. Free Radical Research 33:3, pages 197-215.
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Henrik E. Poulsen, Steffen Loft, Helene Prieme, Kirsten Vistisen, Jens Lykkesfeldt, Kristiina Nyyssonen & Jukka T. Salonen. (1998) Oxidative DNA damage in vivo: Relationship to age, plasma antioxidants, drug metabolism, glutathione-S-transferase activity and urinary creatinine excretion. Free Radical Research 29:6, pages 565-571.
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Sai Yi Pan & Howard Morrison. 2011. Physical Activity and Cancer. Physical Activity and Cancer 135 158 .
Kelsey Fisher-Wellman & Richard J Bloomer. (2009) Acute exercise and oxidative stress: a 30 year history. Dynamic Medicine 8:1.
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Richard J. Bloomer. 2008. 1 50 .
Hideko Nakamoto, Takao Kaneko, Shoichi Tahara, Eri Hayashi, Hisashi Naito, Zsolt Radak & Sataro Goto. (2007) Regular exercise reduces 8-oxodG in the nuclear and mitochondrial DNA and modulates the DNA repair activity in the liver of old rats. Experimental Gerontology 42:4, pages 287-295.
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David J Harriss, N Tim Cable, Keith George, Thomas Reilly, Andrew G Renehan & Najib Haboubi. (2007) Physical Activity Before and After Diagnosis of Colorectal Cancer. Sports Medicine 37:11, pages 947-960.
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Bente Glintborg, Allan Weimann, Thomas W. Kensler & Henrik E. Poulsen. (2006) Oltipraz chemoprevention trial in Qidong, People's Republic of China: Unaltered oxidative biomarkers. Free Radical Biology and Medicine 41:6, pages 1010-1014.
Crossref
Steffen Loft, Peter Svoboda, Hiroshi Kasai, Anne Tjønneland, Ulla Vogel, Peter Møller, Kim Overvad & Ole Raaschou-Nielsen. (2006) Prospective study of 8-oxo-7,8-dihydro-2′-deoxyguanosine excretion and the risk of lung cancer. Carcinogenesis 27:6, pages 1245-1250.
Crossref
Christian P. Fischer, Natalie J. Hiscock, Samar Basu, Bengt Vessby, Anders Kallner, Lars-Börje Sjöberg, Mark A. Febbraio & Bente K. Pedersen. (2006) Vitamin E isoform-specific inhibition of the exercise-induced heat shock protein 72 expression in humans. Journal of Applied Physiology 100:5, pages 1679-1687.
Crossref
Alok Kumar Pandey, Mahima Bajpayee, Devendra Parmar, Subodh K. Rastogi, Neeraj Mathur, Prahlad K. Seth & Alok Dhawan. (2005) DNA damage in lymphocytes of Indian rickshaw pullers as measured by the alkaline comet assay. Environmental and Molecular Mutagenesis 47:1, pages 25-30.
Crossref
Sai Yi Pan, Anne‐Marie Ugnat & Yang Mao. (2005) Physical activity and the risk of ovarian cancer: A case‐control study in Canada. International Journal of Cancer 117:2, pages 300-307.
Crossref
A. Marcuello, J. González-Alonso, J. A. L. Calbet, R. Damsgaard, M. J. López-Pérez & C. Díez-Sánchez. (2005) Skeletal muscle mitochondrial DNA content in exercising humans. Journal of Applied Physiology 99:4, pages 1372-1377.
Crossref
Carolyn Berdanier. 2005. Mitochondria in Health and Disease. Mitochondria in Health and Disease 455 506 .
Niels B J Vollaard, Jerry P Shearman & Chris E Cooper. (2005) Exercise-Induced Oxidative Stress. Sports Medicine 35:12, pages 1045-1062.
Crossref
Marcelo Marcos Piva Demarzo & Sérgio Britto Garcia. (2004) Exhaustive physical exercise increases the number of colonic preneoplastic lesions in untrained rats treated with a chemical carcinogen. Cancer Letters 216:1, pages 31-34.
Crossref
John Kauh & Jay Umbreit. (2004) Colorectal cancer prevention. Current Problems in Cancer 28:5, pages 240-264.
Crossref
Allan Weimann, Bente Riis & Henrik E Poulsen. (2004) Oligonucleotides in human urine do not contain 8-oxo-7,8-dihydrodeoxyguanosine. Free Radical Biology and Medicine 36:11, pages 1378-1382.
Crossref
Angela Mastaloudis, Tian-Wei Yu, Robert P. O'Donnell, Balz Frei, Roderick H. Dashwood & Maret G. Traber. (2004) Endurance exercise results in DNA damage as detected by the comet assay. Free Radical Biology and Medicine 36:8, pages 966-975.
Crossref
KIM C. WESTERLIND. (2003) Physical Activity and Cancer Prevention???Mechanisms. Medicine & Science in Sports & Exercise 35:11, pages 1834-1840.
Crossref
Iman A. Hakim, Robin B. Harris, Sylvia Brown, H-H. Sherry Chow, Sheila Wiseman, Sanjiv Agarwal & Wendy Talbot. (2003) Effect of Increased Tea Consumption on Oxidative DNA Damage among Smokers: A Randomized Controlled Study. The Journal of Nutrition 133:10, pages 3303S-3309S.
Crossref
MALCOLM COLLINS, VAL??RIE RENAULT, LIESL A. GROBLER, ALAN ST CLAIR GIBSON, MICHAEL I. LAMBERT, E. WAYNE DERMAN, GILLIAN S. BUTLER-BROWNE, TIMOTHY D. NOAKES & VINCENT MOULY. (2003) Athletes with Exercise-Associated Fatigue Have Abnormally Short Muscle DNA Telomeres. Medicine & Science in Sports & Exercise 35:9, pages 1524-1528.
Crossref
Antoni Aguiló, Pere Tauler, Maria Pilar Guix, Gerardo Villa, Alfredo Córdova, Josep A Tur & Antoni Pons. (2003) Effect of exercise intensity and training on antioxidants and cholesterol profile in cyclists. The Journal of Nutritional Biochemistry 14:6, pages 319-325.
Crossref
Yuji Sato, Hiroki Nanri, Masanori Ohta, Hiroshi Kasai & Masaharu Ikeda. (2003) Increase of human MTH1 and decrease of 8-hydroxydeoxyguanosine in leukocyte DNA by acute and chronic exercise in healthy male subjects. Biochemical and Biophysical Research Communications 305:2, pages 333-338.
Crossref
Zsolt Radák, Peter Apor, Jozsef Pucsok, Istvan Berkes, Helga Ogonovszky, Gabor Pavlik, Hideko Nakamoto & Sataro Goto. (2003) Marathon running alters the DNA base excision repair in human skeletal muscle. Life Sciences 72:14, pages 1627-1633.
Crossref
Jennifer M. Sacheck & Jeffrey B. Blumberg. (2001) Role of vitamin E and oxidative stress in exercise. Nutrition 17:10, pages 809-814.
Crossref
PETER MØLLER, STEFFEN LOFT, CARSTEN LUNDBY & NIELS VIDIENDAL OLSEN. (2001) Acute hypoxia and hypoxic exercise induce DNA strand breaks and oxidative DNA damage in humans. The FASEB Journal 15:7, pages 1181-1186.
Crossref
Chandan K. Sen. (2001) Antioxidants in Exercise Nutrition. Sports Medicine 31:13, pages 891-908.
Crossref
J Pincemail, J Lecomte, J.P Castiaux, E Collart, R Limet & J.O Defraigne. (2001) Évaluation de l'état de stress oxydatif chez des footballeurs et des basketteurs professionnels. Science & Sports 16:3, pages 168-170.
Crossref
Keizo Umegaki, Pang Daohua, Ayako Sugisawa, Michiyo Kimura & Mitsuru Higuchi. (2000) Influence of one bout of vigorous exercise on ascorbic acid in plasma and oxidative damage to DNA in blood cells and muscle in untrained rats. The Journal of Nutritional Biochemistry 11:7-8, pages 401-407.
Crossref
Andreas Hartmann & Andreas M. Niess. 2000. Handbook of Oxidants and Antioxidants in Exercise. Handbook of Oxidants and Antioxidants in Exercise 195 217 .
Chandan K. Sen, Sashwati Roy & Lester Packer. 2000. Nutrition in Sport. Nutrition in Sport 292 317 .
M. Hirsch-Kauffmann & M. Schweiger. 1999. Reviews of Physiology, Biochemistry and Pharmacology, Volume 139. Reviews of Physiology, Biochemistry and Pharmacology, Volume 139 141 174 .
Steffen Loft & Henrik Enghusen Poulsen. 1999. Advances in DNA Damage and Repair. Advances in DNA Damage and Repair 267 281 .
Andrew R Collins. (1998) Molecular epidemiology in cancer research. Molecular Aspects of Medicine 19:6, pages 359-432.
Crossref

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