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Original Articles

Carnosine and taurine contents in individual fibres of human vastus lateralis muscle

Pages 639-643 | Published online: 01 Dec 2010

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (7)

Kim Van Vossel, Julie Hardeel, Freek Van de Casteele, Sarah de Jager, Eline Lievens, Jan Boone & Wim Derave. (2023) Muscle typology influences the number of repetitions to failure during resistance training. European Journal of Sport Science 23:10, pages 2021-2030.
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Richard Simmonds, James Cole, Jamie Tallent, Owen Jeffries, Nicola Theis & Mark Waldron. (2022) Physiological and thermoregulatory effects of oral taurine supplementation on exercise tolerance during forced convective cooling. European Journal of Sport Science 22:2, pages 209-217.
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Lee Kevin Page, Owen Jeffries & Mark Waldron. (2019) Acute taurine supplementation enhances thermoregulation and endurance cycling performance in the heat. European Journal of Sport Science 19:8, pages 1101-1109.
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Chad M. Kerksick, Colin D. Wilborn, Michael D. Roberts, Abbie Smith-Ryan, Susan M. Kleiner, Ralf Jäger, Rick Collins, Mathew Cooke, Jaci N. Davis, Elfego Galvan, Mike Greenwood, Lonnie M. Lowery, Robert Wildman, Jose Antonio & Richard B. Kreider. (2018) ISSN exercise & sports nutrition review update: research & recommendations. Journal of the International Society of Sports Nutrition 15:1.
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Eric T. Trexler, Abbie E. Smith-Ryan, Jeffrey R. Stout, Jay R. Hoffman, Colin D. Wilborn, Craig Sale, Richard B. Kreider, Ralf Jäger, Conrad P. Earnest, Laurent Bannock, Bill Campbell, Douglas Kalman, Tim N. Ziegenfuss & Jose Antonio. (2015) International society of sports nutrition position stand: Beta-Alanine. Journal of the International Society of Sports Nutrition 12:1.
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Craig Sale, Chester A Hill, James Ponte & Roger C Harris. (2012) β-alanine supplementation improves isometric endurance of the knee extensor muscles. Journal of the International Society of Sports Nutrition 9:1.
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Richard B Kreider, Colin D Wilborn, Lem Taylor, Bill Campbell, Anthony L Almada, Rick Collins, Mathew Cooke, Conrad P Earnest, Mike Greenwood, Douglas S Kalman, Chad M Kerksick, Susan M Kleiner, Brian Leutholtz, Hector Lopez, Lonnie M Lowery, Ron Mendel, Abbie Smith, Marie Spano, Robert Wildman, Darryn S Willoughby, Tim N Ziegenfuss & Jose Antonio. (2010) ISSN exercise & sport nutrition review: research & recommendations. Journal of the International Society of Sports Nutrition 7:1.
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Articles from other publishers (73)

Wannes Swinnen, Eline Lievens, Wouter Hoogkamer, Friedl De Groote, Wim Derave & Benedicte Vanwanseele. (2024) Muscle fibre typology affects whole‐body metabolic rate during isolated muscle contractions and human locomotion. The Journal of Physiology 602:7, pages 1297-1311.
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Eline Lievens, Kim Van Vossel, Freek Van de Casteele, Wim Derave & James B. Murdoch. (2024) The effects of residual dipolar coupling on carnosine in proton muscle spectra. NMR in Biomedicine 37:4.
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Kate Hamilton, Andrew E. Kilding, Daniel J. Plews, Mathew J. Mildenhall, Mark Waldron, Thanchanok Charoensap, Tobias H. Cox, Matthew J. Brick, Warren B. Leigh & Ed Maunder. (2024) Durability of the moderate-to-heavy-intensity transition is related to the effects of prolonged exercise on severe-intensity performance. European Journal of Applied Physiology.
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Wojciech Wójcik, Olga Świder, Monika Łukasiewicz-Mierzejewska, Krzysztof Damaziak, Julia Riedel, Agata Marzec, Michał Wójcicki, Marek Roszko & Jan Niemiec. (2024) Content of amino acids and biogenic amines in stored meat as a result of a broiler diet supplemented with β-alanine and garlic extract. Poultry Science 103:2, pages 103319.
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Thibaux Van der Stede, Jan Spaas, Sarah de Jager, Jana De Brandt, Camilla Hansen, Jan Stautemas, Bjarne Vercammen, Siegrid De Baere, Siska Croubels, Charles‐Henri Van Assche, Berta Cillero Pastor, Michiel Vandenbosch, Ruud Van Thienen, Kenneth Verboven, Dominique Hansen, Thierry Bové, Bruno Lapauw, Charles Van Praet, Karel Decaestecker, Bart Vanaudenaerde, Bert O. Eijnde, Lasse Gliemann, Ylva Hellsten & Wim Derave. (2023) Extensive profiling of histidine‐containing dipeptides reveals species‐ and tissue‐specific distribution and metabolism in mice, rats, and humans. Acta Physiologica 239:1.
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Claudia Kalbe, Katharina Metzger, Claude Gariépy & Marie-France Palin. (2023) Effect of muscle fibre types and carnosine levels on the expression of carnosine-related genes in pig skeletal muscle. Histochemistry and Cell Biology 160:1, pages 63-77.
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Ishay Ostfeld & Jay R. Hoffman. (2023) The Effect of β-Alanine Supplementation on Performance, Cognitive Function and Resiliency in Soldiers. Nutrients 15:4, pages 1039.
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Gloria Vega, Germán Ricaurte, Mauricio Estrada-Castrillón, Harmen Reyngoudt, Oscar M. Cardona, Jaime A. Gallo-Villegas, Raul Narvaez-Sanchez & Juan C. Calderón. (2022) In vivo absolute quantification of carnosine in the vastus lateralis muscle with 1H MRS using a surface coil and water as internal reference. Skeletal Radiology 52:2, pages 157-165.
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Jana De Brandt, Wim Derave, Frank Vandenabeele, Pascal Pomiès, Laura Blancquaert, Charly Keytsman, Marina S. Barusso‐Grüninger, Fabiano F. de Lima, Maurice Hayot, Martijn A. Spruit & Chris Burtin. (2022) Efficacy of 12 weeks oral beta‐alanine supplementation in patients with chronic obstructive pulmonary disease: a double‐blind, randomized, placebo‐controlled trial. Journal of Cachexia, Sarcopenia and Muscle 13:5, pages 2361-2372.
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Eline Lievens, Kim Van Vossel, Freek Van de Casteele, Audrey Baguet & Wim Derave. (2021) Sex-specific maturation of muscle metabolites carnosine, creatine, and carnitine over puberty: a longitudinal follow-up study. Journal of Applied Physiology 131:4, pages 1241-1250.
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J. De Brandt, C. Burtin, P. Pomiès, F. Vandenabeele, K. Verboven, J. Aumann, L. Blancquaert, I. Everaert, L. Van Ryckeghem, J. Cops, M. Hayot, M. A. Spruit & W. Derave. (2021) Carnosine, oxidative and carbonyl stress, antioxidants, and muscle fiber characteristics of quadriceps muscle of patients with COPD. Journal of Applied Physiology 131:4, pages 1230-1240.
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E. Lievens, K. Van Vossel, F. Van de Casteele, M. Krššák, J. B. Murdoch, D. E. Befroy & W. Derave. (2021) CORP: quantification of human skeletal muscle carnosine concentration by proton magnetic resonance spectroscopy. Journal of Applied Physiology 131:1, pages 250-264.
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Ivana Jukić, Nikolina Kolobarić, Ana Stupin, Anita Matić, Nataša Kozina, Zrinka Mihaljević, Martina Mihalj, Petar Šušnjara, Marko Stupin, Željka Breškić Ćurić, Kristina Selthofer-Relatić, Aleksandar Kibel, Anamarija Lukinac, Luka Kolar, Gordana Kralik, Zlata Kralik, Aleksandar Széchenyi, Marija Jozanović, Olivera Galović, Martina Medvidović-Kosanović & Ines Drenjančević. (2021) Carnosine, Small but Mighty—Prospect of Use as Functional Ingredient for Functional Food Formulation. Antioxidants 10:7, pages 1037.
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Kleiner Nemezio, Guilherme de Carvalho Yamaguchi, Ana Paula Boito Ramkrapes, Mariane Leichsenring Schulz, Igor Luchini Baptista, Luiz Augusto Riani, Lívia de Souza Gonçalves, Craig Sale, Marisa Helena Gennari de Medeiros, Bruno Gualano & Guilherme Giannini Artioli. (2021) The role of chronic muscle (in)activity on carnosine homeostasis: a study with spinal cord-injured athletes. American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 320:6, pages R824-R832.
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Adam Mallett, Phillip Bellinger, Wim Derave, Eline Lievens, Ben Kennedy, Hal Rice & Clare Minahan. (2021) Muscle Fiber Typology and Its Association With Start and Turn Performance in Elite Swimmers. International Journal of Sports Physiology and Performance 16:6, pages 834-840.
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Eline Lievens, Phillip Bellinger, Kim Van Vossel, Jan Vancompernolle, Tine Bex, Clare Minahan & Wim Derave. (2021) Muscle Typology of World-Class Cyclists across Various Disciplines and Events. Medicine & Science in Sports & Exercise 53:4, pages 816-824.
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Linda Heskamp, Franciska Lebbink, Mark J. van Uden, Marnix C. Maas, Jurgen A. H. R. Claassen, Martijn Froeling, Graham J. Kemp, Andreas Boss & Arend Heerschap. (2021) Post‐exercise intramuscular O 2 supply is tightly coupled with a higher proximal‐to‐distal ATP synthesis rate in human tibialis anterior . The Journal of Physiology 599:5, pages 1533-1550.
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Qianqian Yu, Xiaojing Tian, Lele Shao, Xingmin Li & Ruitong Dai. (2020) Mitochondria changes and metabolome differences of bovine longissimus lumborum and psoas major during 24 h postmortem. Meat Science 166, pages 108112.
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Bryan Saunders, Mariana Franchi, Luana Farias de Oliveira, Vinicius da Eira Silva, Rafael Pires da Silva, Vitor de Salles Painelli, Luiz Augusto Riani Costa, Craig Sale, Roger Charles Harris, Hamilton Roschel, Guilherme Giannini Artioli & Bruno Gualano. (2018) 24-Week β-alanine ingestion does not affect muscle taurine or clinical blood parameters in healthy males. European Journal of Nutrition 59:1, pages 57-65.
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JOSEPH J. MATTHEWS, GUILHERME G. ARTIOLI, MARK D. TURNER & CRAIG SALE. (2019) The Physiological Roles of Carnosine and β-Alanine in Exercising Human Skeletal Muscle. Medicine & Science in Sports & Exercise 51:10, pages 2098-2108.
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Eimear Dolan, Bryan Saunders, Roger Charles Harris, Jose Eduardo Pereira Wilken Bicudo, David John Bishop, Craig Sale & Bruno Gualano. (2019) Comparative physiology investigations support a role for histidine-containing dipeptides in intracellular acid–base regulation of skeletal muscle. Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology 234, pages 77-86.
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Ulrike Seidel, Patricia Huebbe & Gerald Rimbach. (2018) Taurine: A Regulator of Cellular Redox Homeostasis and Skeletal Muscle Function. Molecular Nutrition & Food Research 63:16.
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Lívia de Souza Gonçalves, Mariana Franchi, Monica B. Mathor, Ademar B. Lugao, Victor H. Carvalho, Marisa H. G. Medeiros, Guilherme Giannini Artioli & Gustavo H. C. Varca. (2019) The molecular structure of β-alanine is resistant to sterilising doses of gamma radiation. PLOS ONE 14:1, pages e0210713.
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Gabriel M.P. Brisola & Alessandro M. Zagatto. (2019) Ergogenic Effects of β-Alanine Supplementation on Different Sports Modalities: Strong Evidence or Only Incipient Findings?. Journal of Strength and Conditioning Research 33:1, pages 253-282.
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Ladislav Valkovič, Radka Klepochová & Martin Krššák. 2018. Muscle Cell and Tissue - Current Status of Research Field. Muscle Cell and Tissue - Current Status of Research Field.
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Colleen S. Deane, Daniel J. WilkinsonBethan E. PhillipsKenneth SmithTimothy Etheridge & Philip J. Atherton. (2017) “Nutraceuticals” in relation to human skeletal muscle and exercise. American Journal of Physiology-Endocrinology and Metabolism 312:4, pages E282-E299.
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Yumiko Takahashi & Hideo Hatta. (2017) Effects of taurine administration on exercise-induced fatigue and recovery. The Journal of Physical Fitness and Sports Medicine 6:1, pages 33-39.
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Ryan Ward, Craig A. Bridge, Lars R. McNaughton & S. Andy Sparks. (2016) The effect of acute taurine ingestion on 4-km time trial performance in trained cyclists. Amino Acids 48:11, pages 2581-2587.
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Jordan J. OutlawAbbie E. Smith-RyanAmanda L. Buckley, Stacie L. UrbinaSara HaywardHailee L. WingfieldBill Campbell, Cliffa Foster, Lem W. Taylor & Colin D. Wilborn. (2016) Effects of β-Alanine on Body Composition and Performance Measures in Collegiate Women. Journal of Strength and Conditioning Research 30:9, pages 2627-2637.
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Laura Blancquaert, Shahid P. Baba, Sebastian Kwiatkowski, Jan Stautemas, Sanne Stegen, Silvia Barbaresi, Weiliang Chung, Adjoa A. Boakye, J. David Hoetker, Aruni Bhatnagar, Joris Delanghe, Bert Vanheel, Maria Veiga‐da‐Cunha, Wim Derave & Inge Everaert. (2016) Carnosine and anserine homeostasis in skeletal muscle and heart is controlled by β‐alanine transamination. The Journal of Physiology 594:17, pages 4849-4863.
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Julian Vallejo, Madoka Spence, An-Lin Cheng, Leticia Brotto, Neile K. Edens, Sean M. Garvey & Marco Brotto. (2016) Cellular and Physiological Effects of Dietary Supplementation with β-Hydroxy-β-Methylbutyrate (HMB) and β-Alanine in Late Middle-Aged Mice. PLOS ONE 11:3, pages e0150066.
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Ivica Just Kukurová, Ladislav Valkovič, Jozef Ukropec, Barbora de Courten, Marek Chmelík, Barbara Ukropcová, Siegfried Trattnig & Martin Krššák. (2015) Improved spectral resolution and high reliability of in vivo 1 H MRS at 7 T allow the characterization of the effect of acute exercise on carnosine in skeletal muscle . NMR in Biomedicine 29:1, pages 24-32.
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Jay R. Hoffman, Jeffrey R. Stout, Roger C. Harris & Daniel S. Moran. (2015) β-Alanine supplementation and military performance. Amino Acids 47:12, pages 2463-2474.
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Sanne Stegen, Inge Everaert, Louise Deldicque, Silvia Vallova, Barbora de Courten, Barbara Ukropcova, Jozef Ukropec & Wim Derave. (2015) Muscle Histidine-Containing Dipeptides Are Elevated by Glucose Intolerance in Both Rodents and Men. PLOS ONE 10:3, pages e0121062.
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Colin Wilborn. 2015. Nutritional Supplements in Sports and Exercise. Nutritional Supplements in Sports and Exercise 223 252 .
T. L. Dutka, C. R. Lamboley, R. M. Murphy & G. D. Lamb. (2014) Acute effects of taurine on sarcoplasmic reticulum Ca 2+ accumulation and contractility in human type I and type II skeletal muscle fibers . Journal of Applied Physiology 117:7, pages 797-805.
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Phillip M. Bellinger. (2014) β-Alanine Supplementation for Athletic Performance. Journal of Strength and Conditioning Research 28:6, pages 1751-1770.
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Alexander A. Boldyrev, Giancarlo Aldini & Wim Derave. (2013) Physiology and Pathophysiology of Carnosine. Physiological Reviews 93:4, pages 1803-1845.
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Trent Stellingwerff, Jacques Decombaz, Roger C. Harris & Chris Boesch. (2012) Optimizing human in vivo dosing and delivery of β-alanine supplements for muscle carnosine synthesis. Amino Acids 43:1, pages 57-65.
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R. C. Harris, J. A. Wise, K. A. Price, H. J. Kim, C. K. Kim & C. Sale. (2012) Determinants of muscle carnosine content. Amino Acids 43:1, pages 5-12.
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Craig Sale, Bryan Saunders & Roger C. Harris. (2009) Effect of beta-alanine supplementation on muscle carnosine concentrations and exercise performance. Amino Acids 39:2, pages 321-333.
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Ashley A Walter, Abbie E Smith, Kristina L Kendall, Jeffrey R Stout & Joel T Cramer. (2010) Six Weeks of High-Intensity Interval Training With and Without β-Alanine Supplementation for Improving Cardiovascular Fitness in Women. Journal of Strength and Conditioning Research 24:5, pages 1199-1207.
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Wim Derave, Inge Everaert, Sam Beeckman & Audrey Baguet. (2010) Muscle Carnosine Metabolism and β-Alanine Supplementation in Relation to Exercise and Training. Sports Medicine 40:3, pages 247-263.
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Eva Blomstrand & Birgitta Essén-Gustavsson. (2008) Changes in amino acid concentration in plasma and type I and type II fibres during resistance exercise and recovery in human subjects. Amino Acids 37:4, pages 629-636.
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Hyo-Jeong Kim. (2008) Comparison of the carnosine and taurine contents of vastus lateralis of elderly Korean males, with impaired glucose tolerance, and young elite Korean swimmers. Amino Acids 36:2, pages 359-363.
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Iain P. Kendrick, Roger C. Harris, Hyo Jeong Kim, Chang Keun Kim, Viet H. Dang, Thanh Q. Lam, Toai T. Bui, Marcus Smith & John A. Wise. (2008) The effects of 10 weeks of resistance training combined with β-alanine supplementation on whole body strength, force production, muscular endurance and body composition. Amino Acids 34:4, pages 547-554.
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