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Original Articles

Mechanistic aspects the dioxin (aryl hydrocarbon) receptor

Pages 261-266 | Published online: 06 Dec 2010

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Quancai Sun, John Marshall Clark & Yeonhwa Park. (2017) Environmental pollutants and type 2 diabetes: a review of human studies. Toxicological & Environmental Chemistry 99:9-10, pages 1283-1303.
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Laurence Kaminsky. (2006) The Role of Trace Metals in Cytochrome P4501 Regulation. Drug Metabolism Reviews 38:1-2, pages 227-234.
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Articles from other publishers (52)

Nour Aldeli, Chadi Soukkarie & Abdulsamie Hanano. (2023) Transcriptional, hormonal and histological alterations in the ovaries of BALB/c mice exposed to TCDD in connection with multigenerational female infertility. Ecotoxicology and Environmental Safety 258, pages 114990.
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Eliška Zgarbová & Radim Vrzal. (2022) The Impact of Indoles Activating the Aryl Hydrocarbon Receptor on Androgen Receptor Activity in the 22Rv1 Prostate Cancer Cell Line. International Journal of Molecular Sciences 24:1, pages 502.
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Zhongkun Du, Kaixuan Hou, Tongtong Zhou, Baihui Shi, Cheng Zhang, Lusheng Zhu, Bing Li, Jinhua Wang & Jun Wang. (2022) Polyhalogenated carbazoles (PHCZs) induce cardiotoxicity and behavioral changes in zebrafish at early developmental stages. Science of The Total Environment 841, pages 156738.
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Chenyang Ji, Chao Shen, Yixi Zhou, Kongyang Zhu, Zhe SunZhenghong Zuo & Meirong Zhao. (2019) AhR Agonist Activity Confirmation of Polyhalogenated Carbazoles (PHCZs) Using an Integration of in Vitro, in Vivo, and in Silico Models. Environmental Science & Technology 53:24, pages 14716-14723.
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Shanjie Zha, Wei Shi, Wenhao Su, Xiaofan Guan & Guangxu Liu. (2019) Exposure to 2,3,7,8-tetrachlorodibenzo-paradioxin (TCDD) hampers the host defense capability of a bivalve species, Tegillarca granosa. Fish & Shellfish Immunology 86, pages 368-373.
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Li Shangguan, Yuanqing Wei, Kan Wang, Yuanjian Zhang & Songqin Liu. (2019) Highly sensitive fluorescent bioassay of 2,3,7,8-tetrachloro-dibenzo-p-dioxin based on abnormal expression of cytochrome P450 1A2 in human cells. Analytica Chimica Acta 1046, pages 179-184.
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Jannick Theobald, Xinlai Cheng, Ali Ghanem, Haristi Gaitantzi, Guangqi Song, Edda Klipp, Judith Wodke, Holger Becker, Ralf Mrowka, Katja Breitkopf-Heinlein, Steven Dooley & Stefan Wölfl. (2017) Monitoring cytochrome P450 activity in living hepatocytes by chromogenic substrates in response to drug treatment or during cell maturation. Archives of Toxicology 92:3, pages 1133-1149.
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Alejandro Barranco, Laura Escudero, Jon Sanz Landaluze & Sandra Rainieri. (2017) Detection of exposure effects of mixtures of heavy polycyclic aromatic hydrocarbons in zebrafish embryos. Journal of Applied Toxicology 37:3, pages 253-264.
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Janina Helle, Manuela I. Bader, Annekathrin M. Keiler, Oliver Zierau, Günter Vollmer, Sridar V. Chittur, Martin Tenniswood & Georg Kretzschmar. (2016) Cross-Talk in the Female Rat Mammary Gland: Influence of Aryl Hydrocarbon Receptor on Estrogen Receptor Signaling. Environmental Health Perspectives 124:5, pages 601-610.
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Vincenza Sofo, Martin Götte, Antonio Simone Laganà, Francesca Maria Salmeri, Onofrio Triolo, Emanuele Sturlese, Giovanni Retto, Maria Alfa, Roberta Granese & Mauricio Simões Abrão. (2015) Correlation between dioxin and endometriosis: an epigenetic route to unravel the pathogenesis of the disease. Archives of Gynecology and Obstetrics 292:5, pages 973-986.
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Gérard Jaouen, Siden Top & Michael J. McGlinchey. 2014. Bioorganometallic Chemistry. Bioorganometallic Chemistry 43 84 .
Maria Teresa Pallotta, Francesca Fallarino, Davide Matino, Antonio Macchiarulo & Ciriana Orabona. (2014) AhR-Mediated, Non-Genomic Modulation of IDO1 Function. Frontiers in Immunology 5.
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Aroha Miller, Jenny E. Hedman, Elisabeth Nyberg, Peter Haglund, Ian T. Cousins, Karin Wiberg & Anders Bignert. (2013) Temporal trends in dioxins (polychlorinated dibenzo-p-dioxin and dibenzofurans) and dioxin-like polychlorinated biphenyls in Baltic herring (Clupea harengus). Marine Pollution Bulletin 73:1, pages 220-230.
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Yu-Sheng Lin, James L. Caffrey, Ping-Chi Hsu, Man-Huei Chang, Mohammed F. Faramawi & Jou-Wei Lin. (2012) Environmental exposure to dioxin-like compounds and the mortality risk in the U.S. population. International Journal of Hygiene and Environmental Health 215:6, pages 541-546.
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Fumiaki Ohtake & Shigeaki Kato. 2011. The AH Receptor in Biology and Toxicology. The AH Receptor in Biology and Toxicology 143 156 .
Fumiaki Ohtake, Yoshiaki Fujii-Kuriyama, Kaname Kawajiri & Shigeaki Kato. (2011) Cross-talk of dioxin and estrogen receptor signals through the ubiquitin system. The Journal of Steroid Biochemistry and Molecular Biology 127:1-2, pages 102-107.
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Natalija Marinković, Daria Pašalić, Goran Ferenčak, Branka Gršković & Ana Rukavina. (2010) Dioxins and Human Toxicity. Archives of Industrial Hygiene and Toxicology 61:4, pages 445-453.
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Daniele F. Staskal, Linda S. Birnbaum & Laurie C. Haws. 2010. Principles and Practice of Mixtures Toxicology. Principles and Practice of Mixtures Toxicology 67 97 .
Carrie R. Fleming, Sonya M. Billiard & Richard T. Di Giulio. (2009) Hypoxia inhibits induction of aryl hydrocarbon receptor activity in topminnow hepatocarcinoma cells in an ARNT-dependent manner. Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology 150:3, pages 383-389.
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Christoph F.A. Vogel & Fumio Matsumura. (2009) A new cross-talk between the aryl hydrocarbon receptor and RelB, a member of the NF-κB family. Biochemical Pharmacology 77:4, pages 734-745.
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Fumiaki Ohtake, Yoshiaki Fujii-Kuriyama & Shigeaki Kato. (2009) AhR acts as an E3 ubiquitin ligase to modulate steroid receptor functions. Biochemical Pharmacology 77:4, pages 474-484.
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Yoshiaki Amakura, Tomoaki Tsutsumi, Kumiko Sasaki, Masafumi Nakamura, Takashi Yoshida & Tamio Maitani. (2008) Influence of food polyphenols on aryl hydrocarbon receptor-signaling pathway estimated by in vitro bioassay. Phytochemistry 69:18, pages 3117-3130.
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Po-Hsiung Lin, Chia-Hua Lin, Chuan-Chen Huang, Ju-Pin Fang & Ming-Chieh Chuang. (2008) 2,3,7,8-Tetrachlorodibenzo- p -Dioxin Modulates the Induction of DNA Strand Breaks and Poly(ADP-ribose) Polymerase-1 Activation by 17β-Estradiol in Human Breast Carcinoma Cells Through Alteration of CYP1A1 and CYP1B1 Expression . Chemical Research in Toxicology 21:7, pages 1337-1347.
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Fumiaki Ohtake, Atsushi Baba, Yoshiaki Fujii-Kuriyama & Shigeaki Kato. (2008) Intrinsic AhR function underlies cross-talk of dioxins with sex hormone signalings. Biochemical and Biophysical Research Communications 370:4, pages 541-546.
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Kaylon L. Bruner-Tran, Grant R. Yeaman, Marta A. Crispens, Toshio M. Igarashi & Kevin G. Osteen. (2008) Dioxin may promote inflammation-related development of endometriosis. Fertility and Sterility 89:5, pages 1287-1298.
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Mercedes Alonso, Susana Casado, Carlos Miranda, José V. Tarazona, José M. Navas & Bernardo Herradón. (2008) Decabromobiphenyl (PBB-209) Activates the Aryl Hydrocarbon Receptor While Decachlorobiphenyl (PCB-209) Is Inactive: Experimental Evidence and Computational Rationalization of the Different Behavior of Some Halogenated Biphenyls. Chemical Research in Toxicology 21:3, pages 643-658.
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Marie-Louise Scippo, Gauthier Eppe, Claude Saegerman, Georges Scholl, Edwin De Pauw, Guy Maghuin-Rogister & Jean-François Focant. 2008. Food Contaminants and Residue Analysis. Food Contaminants and Residue Analysis 457 506 .
Jessica Malavia, Manuela Abalos, F. Javier Santos, Esteban Abad, Josep Rivera & M. Teresa Galceran. (2007) Ion-Trap Tandem Mass Spectrometry for the Analysis of Polychlorinated Dibenzo- p -dioxins, Dibenzofurans, and Dioxin-like Polychlorinated Biphenyls in Food . Journal of Agricultural and Food Chemistry 55:26, pages 10531-10539.
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Fumiaki Ohtake, Atsushi Baba, Ichiro Takada, Maiko Okada, Kei Iwasaki, Hiromi Miki, Sayuri Takahashi, Alexander Kouzmenko, Keiko Nohara, Tomoki Chiba, Yoshiaki Fujii-Kuriyama & Shigeaki Kato. (2007) Dioxin receptor is a ligand-dependent E3 ubiquitin ligase. Nature 446:7135, pages 562-566.
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M Diry, C Tomkiewicz, C Koehle, X Coumoul, K Walter Bock, R Barouki & C Transy. (2006) Activation of the dioxin/aryl hydrocarbon receptor (AhR) modulates cell plasticity through a JNK-dependent mechanism. Oncogene 25:40, pages 5570-5574.
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E. Maria Jönsson, Alexandra Abrahamson, Björn Brunström & Ingvar Brandt. (2006) Cytochrome P4501A induction in rainbow trout gills and liver following exposure to waterborne indigo, benzo[a]pyrene and 3,3′,4,4′,5-pentachlorobiphenyl. Aquatic Toxicology 79:3, pages 226-232.
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Maria E. J?nsson, Carina Carlsson, Richard W. Smith & Peter P?rt. (2006) Effects of copper on CYP1A activity and epithelial barrier properties in the rainbow trout gill. Aquatic Toxicology 79:1, pages 78-86.
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Sandra L. Petersen, Sudha Krishnan & Edward D. Hudgens. (2006) The Aryl Hydrocarbon Receptor Pathway and Sexual Differentiation of Neuroendocrine Functions. Endocrinology 147:6, pages s33-s42.
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Michael Schwarz & Klaus E. Appel. (2005) Carcinogenic risks of dioxin: Mechanistic considerations. Regulatory Toxicology and Pharmacology 43:1, pages 19-34.
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Jouko Tuomisto, Juha Pekkanen, Hannu Kiviranta, Erkki Tukiainen, Terttu Vartiainen, Matti Viluksela & Jouni T. Tuomisto. (2005) Dioxin Cancer Risk — Example of Hormesis?. Dose-Response 3:3, pages dose-response.0.
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Jere Lindén, Merja Korkalainen, Sanna Lensu, Jouko Tuomisto & Raimo Pohjanvirta. (2005) Effects of 2,3,7,8‐tetrachlorodibenzo‐ p ‐dioxin (TCDD) and leptin on hypothalamic mRNA expression of factors participating in food intake regulation in a TCDD‐sensitive and a TCDD‐resistant rat strain . Journal of Biochemical and Molecular Toxicology 19:3, pages 139-148.
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Prabir K. Mandal. (2005) Dioxin: a review of its environmental effects and its aryl hydrocarbon receptor biology. Journal of Comparative Physiology B 175:4, pages 221-230.
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Miriam Jacobs. 2005. Nutrients and Cell Signaling. Nutrients and Cell Signaling.
Clara Y.Y. Chan, Perry M. Kim & Louise M. Winn. (2004) TCDD-induced homologous recombination: the role of the Ah receptor versus oxidative DNA damage. Mutation Research/Genetic Toxicology and Environmental Mutagenesis 563:1, pages 71-79.
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Anton Kocan. 2004. Handbook of Food Analysis, Second Edition -3 Volume Set. Handbook of Food Analysis, Second Edition -3 Volume Set 1363 1401 .
Takashi Moriguchi, Hozumi Motohashi, Tomonori Hosoya, Osamu Nakajima, Satoru Takahashi, Seiichiroh Ohsako, Yasunobu Aoki, Noriko Nishimura, Chiharu Tohyama, Yoshiaki Fujii-Kuriyama & Masayuki Yamamoto. (2003) Distinct response to dioxin in an arylhydrocarbon receptor (AHR)-humanized mouse. Proceedings of the National Academy of Sciences 100:10, pages 5652-5657.
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Merja Korkalainen, Jouko Tuomisto & Raimo Pohjanvirta. (2003) Identification of novel splice variants of ARNT and ARNT2 in the rat. Biochemical and Biophysical Research Communications 303:4, pages 1095-1100.
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Mayumi Ishizuka, Junzo Yonemoto, Hiroko Zaha, Chiharu Tohyama & Hideko Sone. (2003) Perinatal exposure to low doses of 2,3,7,8‐tetrachlorodibenzo‐ p ‐dioxin alters sex‐dependent expression of hepatic CYP2C11 . Journal of Biochemical and Molecular Toxicology 17:5, pages 278-285.
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Jiasheng Song, Margaret Clagett-Dame, Richard E. Peterson, Mark E. Hahn, William M. Westler, Rafal R. Sicinski & Hector F. DeLuca. (2002) A ligand for the aryl hydrocarbon receptor isolated from lung. Proceedings of the National Academy of Sciences 99:23, pages 14694-14699.
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Miriam N. Jacobs*David F. V. Lewis. (2007) Steroid hormone receptors and dietary ligands: a selected review. Proceedings of the Nutrition Society 61:1, pages 105-122.
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Eva Funseth, Martin Påhlman, Maija-Leena Eloranta, Göran Friman & Nils-Gunnar Ilbäck. (2002) Effects of coxsackievirus B3 infection on the acute-phase protein metallothionein and on cytochrome P-4501A1 involved in the detoxification processes of TCDD in the mouse. Science of The Total Environment 284:1-3, pages 37-47.
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Andreas Daxenberger. (2002) Pollutants with androgen-disrupting potency. European Journal of Lipid Science and Technology 104:2, pages 124-130.
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Charbel Massaad, Frida Entezami, Liliane Massade, Mouhamed Benahmed, François Olivennes, Robert Barouki & Samir Hamamah. (2002) How can chemical compounds alter human fertility?. European Journal of Obstetrics & Gynecology and Reproductive Biology 100:2, pages 127-137.
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P.I Mitrou, G Dimitriadis & S.A Raptis. (2001) Toxic effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin and related compounds. European Journal of Internal Medicine 12:5, pages 406-411.
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Merja Korkalainen, Jouko Tuomisto & Raimo Pohjanvirta. (2001) The AH Receptor of the Most Dioxin-Sensitive Species, Guinea Pig, Is Highly Homologous to the Human AH Receptor. Biochemical and Biophysical Research Communications 285:5, pages 1121-1129.
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Diane E. Heck, Amit Roy & Jeffrey D. Laskin. 2001. Biological Reactive Intermediates VI. Biological Reactive Intermediates VI 709 714 .
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