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Original Articles

Azaspiracid poisoning, the food-borne illness associated with shellfish consumption

Pages 879-892 | Received 23 Apr 2004, Accepted 19 Jul 2004, Published online: 20 Feb 2007

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (2)

Roberto CortéS Altamirano & Arturo P. Sierra-Beltrán. (2008) BIOTOXINS FROM FRESHWATER AND MARINE HARMFUL ALGAL BLOOMS OCCURRING IN MEXICO. Toxin Reviews 27:1, pages 27-77.
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V. Economou, C. Papadopoulou, M. Brett, A. Kansouzidou, K. Charalabopoulos, G. Filioussis & K. Seferiadis. (2007) Diarrheic shellfish poisoning due to toxic mussel consumption: The first recorded outbreak in Greece. Food Additives & Contaminants 24:3, pages 297-305.
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Articles from other publishers (40)

Amechi S. Nwankwegu, Lei Zhang, Deti Xie, Okugbe E. Ohore, Yiping Li, Guanglang Yang, Xuexing Yao, Zenghui Song & Qing Yang. (2023) Metabolites dynamics exacerbated by external nutrients inputs into a Ceratium hirundinella-dominated bloom in the Pengxi River, Three Gorges Reservoir, China. Aquatic Toxicology 258, pages 106507.
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Pablo Estevez & Ana Gago-Martinez. (2023) Contribution of Mass Spectrometry to the Advances in Risk Characterization of Marine Biotoxins: Towards the Characterization of Metabolites Implied in Human Intoxications. Toxins 15:2, pages 103.
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Maria Carmen Louzao, Natalia Vilariño, Carmen Vale, Celia Costas, Alejandro Cao, Sandra Raposo-Garcia, Mercedes R. Vieytes & Luis M. Botana. (2022) Current Trends and New Challenges in Marine Phycotoxins. Marine Drugs 20:3, pages 198.
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Xingyi Jiang, Yaqi Zhao, Chunya Tang, Megan Appelbaum & Qinchun Rao. (2022) Aquatic food animals in the United States: Status quo and challenges. Comprehensive Reviews in Food Science and Food Safety 21:2, pages 1336-1382.
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Kazuya Takahashi, Wai Mun Lum, Garry Benico, Hajime Uchida, Mayu Ozawa, Hiroshi Oikawa, Toshiyuki Suzuki, Nguyen Van Nguyen, Dao Viet Ha & Mitsunori Iwataki. (2021) Toxigenic strains of Azadinium poporum (Amphidomataceae, Dinophyceae) from Japan and Vietnam, with first reports of A. poporum (ribotype A) and A. trinitatum in Asian Pacific . Phycological Research 69:3, pages 175-187.
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Joseph V. Rodricks, Duncan Turnbull, Farah Chowdhury & Felicia Wu. 2020. Environmental Toxicants. Environmental Toxicants 149 204 .
Natalia Vilariño, M. Louzao, Paula Abal, Eva Cagide, Cristina Carrera, Mercedes Vieytes & Luis Botana. (2018) Human Poisoning from Marine Toxins: Unknowns for Optimal Consumer Protection. Toxins 10:8, pages 324.
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Mélanie Roué, Hélène Darius & Mireille Chinain. (2018) Solid Phase Adsorption Toxin Tracking (SPATT) Technology for the Monitoring of Aquatic Toxins: A Review. Toxins 10:4, pages 167.
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Santosh Kumar SarkarSantosh Kumar Sarkar. 2018. Marine Algal Bloom: Characteristics, Causes and Climate Change Impacts. Marine Algal Bloom: Characteristics, Causes and Climate Change Impacts 111 170 .
Sara F. Ferreiro, Natalia Vilariño, Cristina Carrera, M. Carmen Louzao, Germán Santamarina, Antonio G. Cantalapiedra, J. Manuel Cifuentes, Andrés Crespo & Luis M. Botana. (2016) In vivo cardiomyocyte response to YTX- and AZA-1-induced damage: autophagy versus apoptosis. Archives of Toxicology 91:4, pages 1859-1870.
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Sara F. Ferreiro, Natalia Vilariño, Cristina Carrera, M. Carmen Louzao, Antonio G. Cantalapiedra, Germán Santamarina, J. Manuel Cifuentes, Andrés C. Vieira & Luis M. Botana. (2016) Subacute Cardiovascular Toxicity of the Marine Phycotoxin Azaspiracid-1 in Rats. Toxicological Sciences 151:1, pages 104-114.
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Kirsty F. Smith, Lesley Rhodes, D. Tim Harwood, Janet Adamson, Catherine Moisan, Rex Munday & Urban Tillmann. (2015) Detection of Azadinium poporum in New Zealand: the use of molecular tools to assist with species isolations. Journal of Applied Phycology 28:2, pages 1125-1132.
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Philipp Hess, Michael J. Twiner, Jane Kilcoyne & Silvio Sosa. 2016. Marine and Freshwater Toxins. Marine and Freshwater Toxins 169 191 .
Philipp Hess, Michael J. Twiner, Jane Kilcoyne & Silvio Sosa. 2014. Marine and Freshwater Toxins. Marine and Freshwater Toxins 1 19 .
Samanta S. Khora. 2015. Hb25_Springer Handbook of Marine Biotechnology. Hb25_Springer Handbook of Marine Biotechnology 789 814 .
Daniel O'Driscoll, Zuzana Škrabáková & Kevin J. James. (2014) Confirmation of extensive natural distribution of azaspiracids in the tissue compartments of mussels (Mytilus edulis). Toxicon 92, pages 123-128.
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Sara F. Ferreiro, Natalia Vilariño, Cristina Carrera, M. Carmen Louzao, Germán Santamarina, Antonio G. Cantalapiedra, Laura P. Rodríguez, J. Manuel Cifuentes, Andrés C. Vieira, K. C. Nicolaou, Michael O. Frederick & Luis M. Botana. (2013) In vivo arrhythmogenicity of the marine biotoxin azaspiracid-2 in rats. Archives of Toxicology 88:2, pages 425-434.
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Soheil Chegini, Sarah J. Austin & Dean D. Metcalfe. 2013. Food Allergy. Food Allergy 518 534 .
Thierry Jauffrais, Claire Marcaillou, Christine Herrenknecht, Philippe Truquet, Véronique Séchet, Elodie Nicolau, Urban Tillmann & Philipp Hess. (2012) Azaspiracid accumulation, detoxification and biotransformation in blue mussels (Mytilus edulis) experimentally fed Azadinium spinosum. Toxicon 60:4, pages 582-595.
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Michael J. Twiner, Racha El-Ladki, Jane Kilcoyne & Gregory J. Doucette. (2012) Comparative Effects of the Marine Algal Toxins Azaspiracid-1, -2, and -3 on Jurkat T Lymphocyte Cells. Chemical Research in Toxicology 25:3, pages 747-754.
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Aurelia Tubaro, Silvio Sosa & James Hungerford. 2012. Veterinary Toxicology. Veterinary Toxicology 896 934 .
Hyukjae Choi, Alban R. Pereira & William H. Gerwick. 2012. Handbook of Marine Natural Products. Handbook of Marine Natural Products 55 152 .
Daniel O’Driscoll, Zuzana Škrabáková, John O’Halloran, Frank N. A. M. van Pelt & Kevin J. James. (2011) Mussels Increase Xenobiotic (Azaspiracid) Toxicity Using a Unique Bioconversion Mechanism. Environmental Science & Technology 45:7, pages 3102-3108.
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Paulo Vale. (2011) Biotoxinas emergentes em águas europeias e novos riscos para a saúde pública. Revista Portuguesa de Saúde Pública 29:1, pages 77-87.
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Zuzana Škrabáková, John O'Halloran, Frank N.A.M. van Pelt & Kevin J. James. (2010) Food contaminant analysis at ultra‐high mass resolution: application of hybrid linear ion trap – orbitrap mass spectrometry for the determination of the polyether toxins, azaspiracids, in shellfish. Rapid Communications in Mass Spectrometry 24:20, pages 2966-2974.
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Ambrose Furey, Sinead O'Doherty, Keith O'Callaghan, Mary Lehane & Kevin J. James. (2010) Azaspiracid poisoning (AZP) toxins in shellfish: Toxicological and health considerations. Toxicon 56:2, pages 173-190.
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Arjen Gerssen, Erik H. W. van Olst, Patrick P. J. Mulder & Jacob de Boer. (2010) In-house validation of a liquid chromatography tandem mass spectrometry method for the analysis of lipophilic marine toxins in shellfish using matrix-matched calibration. Analytical and Bioanalytical Chemistry 397:7, pages 3079-3088.
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K. J. JAMES, B. CAREY, J. O'HALLORAN, F. N. A. M. van PELT & Z. ŠKRABÁKOVÁ. (2010) Shellfish toxicity: human health implications of marine algal toxins. Epidemiology and Infection 138:7, pages 927-940.
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Arjen Gerssen, Irene E. Pol-Hofstad, Marnix Poelman, Patrick P.J. Mulder, Hester J. Van den Top & Jacob De Boer. (2010) Marine Toxins: Chemistry, Toxicity, Occurrence and Detection, with Special Reference to the Dutch Situation. Toxins 2:4, pages 878-904.
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A. López-Rivera, K. O’Callaghan, M. Moriarty, D. O’Driscoll, B. Hamilton, M. Lehane, K.J. James & A. Furey. (2010) First evidence of azaspiracids (AZAs): A family of lipophilic polyether marine toxins in scallops (Argopecten purpuratus) and mussels (Mytilus chilensis) collected in two regions of Chile. Toxicon 55:4, pages 692-701.
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Michael O. Frederick , Sandra De Lamo Marin, Kim D. Janda, K. C. Nicolaou  & Tobin J. Dickerson. (2009) Monoclonal Antibodies with Orthogonal Azaspiracid Epitopes. ChemBioChem 10:10, pages 1625-1629.
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G. Boyer. 2009. Shellfish Safety and Quality. Shellfish Safety and Quality 129 161 .
Donald G. Barceloux. 2008. Medical Toxicology of Natural Substances. Medical Toxicology of Natural Substances 218 221 .
. (2008) Marine biotoxins in shellfish – Azaspiracid group ‐ Scientific Opinion of the Panel on Contaminants in the Food chain. EFSA Journal 6:10.
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Michael Twiner, Nils Rehmann, Philipp Hess & Gregory Doucette. (2008) Azaspiracid Shellfish Poisoning: A Review on the Chemistry, Ecology, and Toxicology with an Emphasis on Human Health Impacts. Marine Drugs 6:2, pages 39-72.
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Trine Torgersen, Nanna Bruun Bremnes, Thomas Rundberget & Tore Aune. (2008) Structural confirmation and occurrence of azaspiracids in Scandinavian brown crabs (Cancer pagurus). Toxicon 51:1, pages 93-101.
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Ambrose Furey, Javier García, Keith O'Callaghan, Mary Lehane, Mónica Fernández Amandi & Kevin J. James. 2007. Phycotoxins: Chemistry and Biochemistry. Phycotoxins: Chemistry and Biochemistry 19 46 .
Natalia Vilariño. 2007. Phycotoxins: Chemistry and Biochemistry. Phycotoxins: Chemistry and Biochemistry 311 318 .
Aurelia Tubaro & James Hungerford. 2007. Veterinary Toxicology. Veterinary Toxicology 725 752 .
Sandra E. Shumway, JoAnn M. Burkholder & Jeffrey Springer. (2006) Effects of the estuarine dinoflagellate Pfiesteria shumwayae (Dinophyceae) on survival and grazing activity of several shellfish species. Harmful Algae 5:4, pages 442-458.
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