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Food Additives & Contaminants Volume 22, 2005 - Issue 6
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Original Articles

The occurrence of nitrofuran metabolites in the tissues of chickens exposed to very low dietary concentrations of the nitrofurans

R. J Mccracken Chemical Surveillance Department, Veterinary Sciences Division, Department of Agriculture and Rural Development, Belfast, Northern Ireland, UK
,
J. A Van Rhijn State Institute for Quality Control of Agricultural Products, RIKILT-DLO, Wageningen, The Netherlands
&
D. G Kennedy Dr Chemical Surveillance Department, Veterinary Sciences Division, Department of Agriculture and Rural Development, Belfast, Northern Ireland, UK
Pages 567-572 | Received 16 Feb 2004, Accepted 22 Mar 2005, Published online: 20 Feb 2007

Citations (33)

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Girma Regassa Fayissa, Simiso Dube & Mathew Muzi Nindi. (2023) Fast screening method to determine metabolites of nitrofurans in chicken meat using partitioned dispersive liquid–liquid microextraction combined with HPLC/DAD. Food Additives & Contaminants: Part A 40:1, pages 56-66.
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Huamei Yang, Xiaoli Jiang, Yanli Wang, Chen Li, Li Hang & Weihong Huang. (2021) Determination of semicarbazide residue in human urine samples using liquid chromatography-tandem mass spectrometry. Food Additives & Contaminants: Part A 38:6, pages 922-930.
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R.J. McCracken & D.G. Kennedy. (2013) Furazolidone in chicken: case study of an incident of widespread contamination. British Poultry Science 54:6, pages 704-712.
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Justin G. Bendall. (2009) Semicarbazide is non-specific as a marker metabolite to reveal nitrofurazone abuse as it can form under Hofmann conditions. Food Additives & Contaminants: Part A 26:1, pages 47-56.
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K. M. Cooper, R. J. Mccracken, M. Buurman & D. G. Kennedy. (2008) Residues of nitrofuran antibiotic parent compounds and metabolites in eyes of broiler chickens. Food Additives & Contaminants: Part A 25:5, pages 548-556.
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J. R. Wang & L. Y. Zhang. (2006) Simultaneous Determination and Identification of Furazolidone, Furaltadone, Nitrofurazone, and Nitrovin in Feeds by HPLC and LC‐MS. Journal of Liquid Chromatography & Related Technologies 29:3, pages 377-390.
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Articles from other publishers (27)

Jingchao Guo, Liyun Zhang, Yongxia Zhao, Awais Ihsan, Xu Wang & Yanfei Tao. (2023) Study on the Metabolic Transformation Rule of Enrofloxacin Combined with Tilmicosin in Laying Hens. Metabolites 13:4, pages 528.
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Amanda Pacholak, Agnieszka Zgoła-Grześkowiak & Ewa Kaczorek. (2023) Dynamics of microbial communities during biotransformation of nitrofurantoin. Environmental Research 216, pages 114531.
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A. O. Melekhin, V. V. Tolmacheva, Yu. N. Kholyavskaya, E. S. Sedykh, S. G. Dmitrienko, V. V. Apyari & A. L. Bairov. (2022) Rapid Hydrolysis and Derivatization of Nitrofuran Metabolites with a New Derivatizing Agent 5-Nitro-2-Furaldehyde in Their Determination in Chicken Meat by HPLC–MS/MS. Journal of Analytical Chemistry 77:10, pages 1300-1306.
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Michael O'Keeffe, Anna Christodoulidou & Carlo Nebbia. (2021) Presence of nitrofurans and their metabolites in gelatine. EFSA Journal 19:10.
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Xiuhui Tian, Huanjun Li, Dianfeng Han, Fenggong Wen, Huan Liu, Ge Liu, Kaixiu Peng, Xianghong Gong, Xin Liu, Weiyun Wang, Haixia Yu & Yingjiang Xu. (2021) Sources, Toxicity and Detection Techniques of Semicarbazide: A Review. Journal of Ocean University of China 20:5, pages 1263-1275.
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Lihong Xing, Weihong Sun, Xiaojie Sun, Jixing Peng, Zhaoxin Li, Panpan Zhu & Xuying Zheng. (2021) Semicarbazide Accumulation, Distribution and Chemical Forms in Scallop (Chlamys farreri) after Seawater Exposure. Animals 11:6, pages 1500.
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Jigyasa & Jaspreet Kaur Rajput. 2021. Management of Contaminants of Emerging Concern (CEC) in Environment. Management of Contaminants of Emerging Concern (CEC) in Environment 179 204 .
Justin G. Bendall, Robert A. Crawford, Jaap M. Evers, Betty W. Smythe, Thomas Bessaire, Pascal Mottier, Claudia Mujahid, Gordana Aleksic & Robert Hutchinson. (2019) Determination of nitrofurazone in fluid milk and dairy powders. Part 1: An international pilot study. International Dairy Journal 91, pages 185-192.
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Jin-Wook Kwon. (2017) Semicarbazide: Natural occurrence and uncertain evidence of its formation from food processing. Food Control 72, pages 268-275.
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. (2015) Scientific Opinion on nitrofurans and their metabolites in food. EFSA Journal 13:6.
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Sijun Deng, Shusheng Tang, Shen Zhang, Chaoming Zhang, Congcong Wang, Yan Zhou, Chongshan Dai & Xilong Xiao. (2015) Furazolidone induces apoptosis through activating reactive oxygen species-dependent mitochondrial signaling pathway and suppressing PI3K/Akt signaling pathway in HepG2 cells. Food and Chemical Toxicology 75, pages 173-186.
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Hamed Meskarpour Amiri, Hamidreza Tavakoli, Ghavam Hashemi, Tanaz Mousavi, Hosein Rostami, Mohammad Gholami Fesharaki & Mohammadmahdi Gholian. (2014) The Occurrence of Residues of Furazolidone Metabolite, 3-Amino-2-Oxazolidone, in Eggs Distributed in Mazandaran Province, Iran. Scimetr 2:4.
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Edward L.E. Jester, Ann Abraham, Yuesong Wang, Kathleen R. El Said & Steven M. Plakas. (2014) Performance evaluation of commercial ELISA kits for screening of furazolidone and furaltadone residues in fish. Food Chemistry 145, pages 593-598.
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Jorge Barbosa, Andreia Freitas, José Luis Mourão, Maria Irene Noronha da Silveira & Fernando Ramos. (2012) Determination of Furaltadone and Nifursol Residues in Poultry Eggs by Liquid Chromatography–Electrospray Ionization Tandem Mass Spectrometry. Journal of Agricultural and Food Chemistry 60:17, pages 4227-4234.
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Jorge Barbosa, Andreia Freitas, Sara Moura, José Luis Mourão, Maria Irene Noronha da Silveira & Fernando Ramos. (2011) Detection, Accumulation, Distribution, and Depletion of Furaltadone and Nifursol Residues in Poultry Muscle, Liver, and Gizzard. Journal of Agricultural and Food Chemistry 59:22, pages 11927-11934.
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Colin S. Thompson, Imelda M. Traynor, Terence L. Fodey, Steven R.H. Crooks & D. Glenn Kennedy. (2011) Screening method for the detection of a range of nitrofurans in avian eyes by optical biosensor. Analytica Chimica Acta 700:1-2, pages 177-182.
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Nobuo Sasaki, Tomoyuki Matsumoto, Yoshinori Ikenaka, Akio Kazusaka, Mayumi Ishizuka & Shoichi Fujita. (2011) Furazolidone induces the activity of microsomal enzymes that metabolize furazolidone in chickens. Pesticide Biochemistry and Physiology 100:2, pages 135-139.
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Christof Van Poucke, Christ'l Detavernier, Mathieu Wille, Jan Kwakman, Patrick Sorgeloos & Carlos Van Peteghem. (2011) Investigation into the Possible Natural Occurence of Semicarbazide in Macrobrachium rosenbergii Prawns. Journal of Agricultural and Food Chemistry 59:5, pages 2107-2112.
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Jun Li, Jing Liu, Hui-Cai Zhang, Hui Li & Jian-Ping Wang. (2010) Broad specificity indirect competitive immunoassay for determination of nitrofurans in animal feeds. Analytica Chimica Acta 678:1, pages 1-6.
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Shau Grossman & Neil D. Danielson. (2009) Methylammonium formate as a mobile phase modifier for totally aqueous reversed-phase liquid chromatography. Journal of Chromatography A 1216:16, pages 3578-3586.
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Jun Li, Ju Xiang Liu & Jian Ping Wang. (2009) Multidetermination of Four Nitrofurans in Animal Feeds by a Sensitive and Simple Enzyme-Linked Immunosorbent Assay. Journal of Agricultural and Food Chemistry 57:6, pages 2181-2185.
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Laddawan KRONGPONG, Kunihiko FUTAMI, Takayuki KATAGIRI, Makoto ENDO & Masashi MAITA. (2008) Application of ELISA-based kit for detecting AOZ and determining its clearance in eel tissues. Fisheries Science 74:5, pages 1055-1061.
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M. Vass, K. Hruska & M. Franek. (2008) Nitrofuran antibiotics: a review on the application, prohibition and residual analysis. Veterinární medicína 53:9, pages 469-500.
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J.V. Samsonova, A.J. Douglas, K.M. Cooper, D.G. Kennedy & C.T. Elliott. (2008) The identification of potential alternative biomarkers of nitrofurazone abuse in animal derived food products. Food and Chemical Toxicology 46:5, pages 1548-1554.
Crossref
Masakazu HORIE, Yayoi TABARA, Rie ISHII, Kazuaki HASHIMOTO & Youko YAMAGISHI. (2008) Determination of Nitrofurazone in Livestock Products and Seafoods by Liquid Chromatography-Tandem Mass Spectrometry. Journal of the Food Hygienic Society of Japan (Shokuhin Eiseigaku Zasshi) 49:3, pages 204-210.
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Hanaa H. Ahmed, Sekena H. Abd El-Aziem & Mosaad A. Abdel-Wahhab. (2008) Potential role of cysteine and methionine in the protection against hormonal imbalance and mutagenicity induced by furazolidone in female rats. Toxicology 243:1-2, pages 31-42.
Crossref
Sherri B. Turnipseed & Wendy C. Andersen. 2008. Food Contaminants and Residue Analysis. Food Contaminants and Residue Analysis 307 338 .

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