1,143
Views
46
CrossRef citations to date
0
Altmetric
Original Articles

DNA adduct formation by ochratoxin A: Review of the available evidence

&
Pages 65-74 | Published online: 09 Aug 2006

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (3)

Frantisek Malir, Vladimir Ostry & Eva Novotna. (2013) Toxicity of the mycotoxin ochratoxin A in the light of recent data. Toxin Reviews 32:2, pages 19-33.
Read now
P. Burdaspal & T. Legarda. (2007) Occurrence of ochratoxin A in sweet wines produced in Spain and other countries. Food Additives & Contaminants 24:9, pages 976-986.
Read now
A. Zinedine, J. M. Soriano, C. Juan, B. Mojemmi, J. C. Moltó, A. Bouklouze, Y. Cherrah, L. Idrissi, R. El Aouad & J. Mañes. (2007) Incidence of ochratoxin A in rice and dried fruits from Rabat and Salé area, Morocco. Food Additives & Contaminants 24:3, pages 285-291.
Read now

Articles from other publishers (43)

Gerald Schwerdt, Michael Kopf & Michael Gekle. (2023) The nephrotoxin ochratoxin a impairs resilience of energy homeostasis of human proximal tubule cells. Mycotoxin Research 39:4, pages 393-403.
Crossref
Seema Zargar & Tanveer A. Wani. (2023) Food Toxicity of Mycotoxin Citrinin and Molecular Mechanisms of Its Potential Toxicity Effects through the Implicated Targets Predicted by Computer-Aided Multidimensional Data Analysis. Life 13:4, pages 880.
Crossref
Tetyana Kobets, Benjamin P. C. Smith & Gary M. Williams. (2022) Food-Borne Chemical Carcinogens and the Evidence for Human Cancer Risk. Foods 11:18, pages 2828.
Crossref
Barbara De Santis, Emanuela Gregori, Francesca Debegnach, Gabriele Moracci, Chiara Saitta & Carlo Brera. (2020) Determination of ochratoxin A in pork meat products: single laboratory validation method and preparation of homogeneous batch materials. Mycotoxin Research 36:2, pages 235-241.
Crossref
Nelly Babayan, Gohar Tadevosyan, Lusine Khondkaryan, Ruzanna Grigoryan, Natalya Sarkisyan, Rouben Haroutiounian & Helga Stopper. (2019) Ochratoxin A induces global DNA hypomethylation and oxidative stress in neuronal cells in vitro. Mycotoxin Research 36:1, pages 73-81.
Crossref
Paulina Markowiak, Katarzyna Śliżewska, Adriana Nowak, Agnieszka Chlebicz, Artur Żbikowski, Karol Pawłowski & Piotr Szeleszczuk. (2019) Probiotic microorganisms detoxify ochratoxin A in both a chicken liver cell line and chickens. Journal of the Science of Food and Agriculture 99:9, pages 4309-4318.
Crossref
Gordon C. Hard. (2018) Mechanisms of Rodent Renal Carcinogenesis Revisited. Toxicologic Pathology 46:8, pages 956-969.
Crossref
Michael Higgins, Ismael Obaidi & Tara McMorrow. 2018. Cancer Causing Substances. Cancer Causing Substances.
A.-M. Domijan & M. Peraica. 2018. Comprehensive Toxicology. Comprehensive Toxicology 154 167 .
Hyun Jung Lee & Dojin Ryu. (2017) Worldwide Occurrence of Mycotoxins in Cereals and Cereal-Derived Food Products: Public Health Perspectives of Their Co-occurrence. Journal of Agricultural and Food Chemistry 65:33, pages 7034-7051.
Crossref
Agnieszka Loboda, Anna Stachurska, Mateusz Sobczak, Paulina Podkalicka, Olga Mucha, Alicja Jozkowicz & Jozef Dulak. (2017) Nrf2 deficiency exacerbates ochratoxin A-induced toxicity in vitro and in vivo. Toxicology 389, pages 42-52.
Crossref
Marie Stiborová, Volker M. Arlt & Heinz H. Schmeiser. (2016) Balkan endemic nephropathy: an update on its aetiology. Archives of Toxicology 90:11, pages 2595-2615.
Crossref
Jelka Pleadin, Nina Kudumija, Dragan Kovačević, Giampiero Scortichini, Salvatore Milone & Ivana Kmetič. (2016) Comparison of ochratoxin A levels in edible pig tissues and in biological fluids after exposure to a contaminated diet. Mycotoxin Research 32:3, pages 145-151.
Crossref
Carlotta Giromini, Raffaella Rebucci, Eleonora Fusi, Luciana Rossi, Francesca Saccone & Antonella Baldi. (2016) Cytotoxicity, apoptosis, DNA damage and methylation in mammary and kidney epithelial cell lines exposed to ochratoxin A. Cell Biology and Toxicology 32:3, pages 249-258.
Crossref
Chit Woo & Hani El-Nezami. (2016) Maternal-Fetal Cancer Risk Assessment of Ochratoxin A during Pregnancy. Toxins 8:4, pages 87.
Crossref
Lucia Rutigliano, Luisa Valentini, Nicola Antonio Martino, Flavia Pizzi, Antonina Zanghì, Maria Elena Dell'Aquila & Fiorenza Minervini. (2015) Ochratoxin A at low concentrations inhibits in vitro growth of canine umbilical cord matrix mesenchymal stem cells through oxidative chromatin and DNA damage. Reproductive Toxicology 57, pages 121-129.
Crossref
Alexandra Heussner & Lewis Bingle. (2015) Comparative Ochratoxin Toxicity: A Review of the Available Data. Toxins 7:10, pages 4253-4282.
Crossref
Clara Y. Chan & Bruce J. Kelman. 2015. Hamilton & Hardy's Industrial Toxicology. Hamilton & Hardy's Industrial Toxicology 1283 1294 .
Chiara Bernardini, Ester Grilli, Johanna Catharina Duvigneau, Augusta Zannoni, Benedetta Tugnoli, Fabio Gentilini, Terenzio Bertuzzi, Silvia Spinozzi, Cecilia Camborata, Maria Laura Bacci, Andrea Piva & Monica Forni. (2014) Cellular stress marker alteration and inflammatory response in pigs fed with an ochratoxin contaminated diet. Research in Veterinary Science 97:2, pages 244-250.
Crossref
Sevtap Aydin, Şaziye Sezin Palabiyik, Pinar Erkekoglu, Gonul Sahin, Nurşen Başaran & Belma Kocer Giray. (2013) The carotenoid lycopene protects rats against DNA damage induced by Ochratoxin A. Toxicon 73, pages 96-103.
Crossref
Ayse Gul Mutlu. (2012) Increase in Mitochondrial DNA Copy Number in Response to Ochratoxin A and Methanol-Induced Mitochondrial DNA Damage in Drosophila. Bulletin of Environmental Contamination and Toxicology 89:6, pages 1129-1132.
Crossref
L.A. Corcuera, A. Vettorazzi, L. Arbillaga, E. González-Peñas & A. López de Cerain. (2012) An approach to the toxicity and toxicokinetics of aflatoxin B1 and ochratoxin A after simultaneous oral administration to fasted F344 rats. Food and Chemical Toxicology 50:10, pages 3440-3446.
Crossref
L.A. Corcuera, S. Amézqueta, L. Arbillaga, A. Vettorazzi, S. Touriño, J.L. Torres & A. López de Cerain. (2012) A polyphenol-enriched cocoa extract reduces free radicals produced by mycotoxins. Food and Chemical Toxicology 50:3-4, pages 989-995.
Crossref
Annie Pfohl-Leszkowicz & Richard A. Manderville. (2011) An Update on Direct Genotoxicity as a Molecular Mechanism of Ochratoxin A Carcinogenicity. Chemical Research in Toxicology 25:2, pages 252-262.
Crossref
L.A. Corcuera, L. Arbillaga, A. Vettorazzi, A. Azqueta & A. López de Cerain. (2011) Ochratoxin A reduces aflatoxin B1 induced DNA damage detected by the comet assay in Hep G2 cells. Food and Chemical Toxicology 49:11, pages 2883-2889.
Crossref
Kristin Czakai, Katja Müller, Pasquale Mosesso, Gaetano Pepe, Markus Schulze, Antje Gohla, Debasis Patnaik, Wolfgang Dekant, Jonathan M.G. Higgins & Angela Mally. (2011) Perturbation of Mitosis through Inhibition of Histone Acetyltransferases: The Key to Ochratoxin A Toxicity and Carcinogenicity?. Toxicological Sciences 122:2, pages 317-329.
Crossref
Abdellah Zinedine. (2010) Ochratoxin A in Moroccan Foods: Occurrence and Legislation. Toxins 2:5, pages 1121-1133.
Crossref
Ali Arjomand. (2010) Accelerator mass spectrometry-enabled studies: current status and future prospects. Bioanalysis 2:3, pages 519-541.
Crossref
Shohei Sakuda & Makoto Kimura. 2010. Comprehensive Natural Products II. Comprehensive Natural Products II 411 455 .
A.-M. Domijan & M. Peraica. 2010. Comprehensive Toxicology. Comprehensive Toxicology 125 137 .
Lada Rumora & Tihana Grubišić. (2009) A Journey Through Mitogen-Activated Protein Kinase and Ochratoxin A Interactions. Archives of Industrial Hygiene and Toxicology 60:4, pages 449-456.
Crossref
Erwin Märtlbauer, Ewald Usleber, Richard Dietrich & Elisabeth Schneider. (2009) Ochratoxin A in human blood serum – retrospective long-term data. Mycotoxin Research 25:4, pages 175-186.
Crossref
Melanie Adler, Katja Müller, Eva Rached, Wolfgang Dekant & Angela Mally. (2009) Modulation of key regulators of mitosis linked to chromosomal instability is an early event in ochratoxin A carcinogenicity. Carcinogenesis 30:4, pages 711-719.
Crossref
Kaoru Inoue, Midori Yoshida, Miwa Takahashi, Hitoshi Fujimoto, Kuniyoshi Ohnishi, Koichi Nakashima, Makoto Shibutani, Masao Hirose & Akiyoshi Nishikawa. (2009) Possible contribution of rubiadin, a metabolite of madder color, to renal carcinogenesis in rats. Food and Chemical Toxicology 47:4, pages 752-759.
Crossref
Angela Mally & Wolfgang Dekant. (2009) Mycotoxins and the kidney: Modes of action for renal tumor formation by ochratoxin A in rodents. Molecular Nutrition & Food Research 53:4, pages 467-478.
Crossref
Maricel Marin-Kuan, Christophe Cavin, Thierry Delatour & Benoît Schilter. (2008) Ochratoxin A carcinogenicity involves a complex network of epigenetic mechanisms. Toxicon 52:2, pages 195-202.
Crossref
Pasquale Mosesso, Serena Cinelli, Raffaela Bellacima & Gaetano Pepe. (2008) In Vitro Cytogenetic Results Supporting a DNA Nonreactive Mechanism for Ochratoxin A, Potentially Relevant for Its Carcinogenicity. Chemical Research in Toxicology 21:6, pages 1235-1243.
Crossref
Thierry Delatour, Angela Mally, Janique Richoz, Sibel Özden, Wolfgang Dekant, Heiko Ihmels, Daniela Otto, Didier Gasparutto, Maricel Marin‐Kuan, Benoît Schilter & Christophe Cavin. (2008) Absence of 2′‐deoxyguanosine‐carbon 8‐bound ochratoxin A adduct in rat kidney DNA monitored by isotope dilution LC‐MS/MS. Molecular Nutrition & Food Research 52:4, pages 472-482.
Crossref
Kaoru Inoue, Makoto Shibutani, Naoya Masutomi, Kazuhiro Toyoda, Hironori Takagi, Chikako Uneyama, Akiyoshi Nishikawa & Masao Hirose. (2008) A 13-week subchronic toxicity study of madder color in F344 rats. Food and Chemical Toxicology 46:1, pages 241-252.
Crossref
A. Mally, G.C. Hard & W. Dekant. (2007) Ochratoxin A as a potential etiologic factor in endemic nephropathy: Lessons from toxicity studies in rats. Food and Chemical Toxicology 45:11, pages 2254-2260.
Crossref
Leire Arbillaga, Amaia Azqueta, Joost H.M. van Delft & Adela López de Cerain. (2007) In vitro gene expression data supporting a DNA non-reactive genotoxic mechanism for ochratoxin A. Toxicology and Applied Pharmacology 220:2, pages 216-224.
Crossref
. (2006) Opinion of the Scientific Panel on contaminants in the food chain [CONTAM] related to ochratoxin A in food. EFSA Journal 4:6, pages 365.
Crossref
Angela Mally, Martina Decker, Michaela Bekteshi & Wolfgang Dekant. (2006) Ochratoxin A alters cell adhesion and gap junction intercellular communication in MDCK cells. Toxicology 223:1-2, pages 15-25.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.