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Guest Editorial

Conclusions from the workshops on Ochratoxin A in Food: Recent developments and significance, organized by ILSI Europe in Baden (Austria), 29 June–1 July 2005

Pages 1-5 | Published online: 09 Aug 2006

Keep up to date with the latest research on this topic with citation updates for this article.

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Rana Muhammad Bilal, Muhammad Ali Tahir, Asim Shahzad, Mayada R. Farag, Abdelmonem Siddiq, Nahed A. El-Shall, Kuldeep Dhama, Shaaban S. Elnesr & Mahmoud Alagawany. (2023) Yeast and derived products: their uses in preventing mycotoxins in poultry feeds. World's Poultry Science Journal 79:2, pages 351-378.
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Mohammadreza Khalesi, Mahmoud Tabrizchi & Mahmoud Sheikh-Zeinoddin. (2013) The effects of temperature and relative humidity on ochratoxin A formation in fresh liquorice root. Food Additives & Contaminants: Part A 30:2, pages 339-344.
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Imen Ayed-Boussema, Jean Marc Pascussi, Chiraz Zaied, Patrick Maurel, Hassen Bacha & Wafa Hassen. (2012) Ochratoxin A induces CYP3A4, 2B6, 3A5, 2C9, 1A1, and CYP1A2 gene expression in primary cultured human hepatocytes: a possible activation of nuclear receptors. Drug and Chemical Toxicology 35:1, pages 71-80.
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T. Kuiper-Goodman, C. Hilts, S.M. Billiard, Y. Kiparissis, I.D.K. Richard & S. Hayward. (2010) Health risk assessment of ochratoxin A for all age-sex strata in a market economy. Food Additives & Contaminants: Part A 27:2, pages 212-240.
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A. M. Pacin, E. V. Ciancio Bovier, E. Motta, S. L. Resnik, D. Villa & M. Olsen. (2008) Survey of Argentinean human plasma for ochratoxin A. Food Additives & Contaminants: Part A 25:5, pages 635-641.
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A. Ariño, M. Herrera, E. Langa, J. Raso & A. Herrera. (2007) Ochratoxin A in liquorice as affected by processing methods. Food Additives & Contaminants 24:9, pages 987-992.
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Vladisav Stefanovic, Bojan Jelakovic, Rade Cukuranovic, Dana Bukvic, Jovan Nikolic, Ljiljana Lukic, Gheorge Gluhovschi, Draga Toncheva, Momir Polenakovic & Jean-Pierre Cosyns. (2007) Diagnostic Criteria for Balkan Endemic Nephropathy: Proposal by an International Panel. Renal Failure 29:7, pages 867-880.
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Stela Živčić-Ćosić, Mirjana Gržetić, Maksim Valenčić, Romano Oguić, Anton Maričić, Gordana Đorđević, Sanja Balen, Lidija Orlić, Sanjin Rački & Željko Fučkar. (2007) Urothelial Cancer in Patients with Endemic Balkan Nephropathy (EN) after Renal Transplantation. Renal Failure 29:7, pages 861-865.
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Jean Lou C. M. Dorne, Martina Cirlini, Jochem Louisse, Lorenzo Pedroni, Gianni Galaverna & Luca Dellafiora. (2022) A Computational Understanding of Inter-Individual Variability in CYP2D6 Activity to Investigate the Impact of Missense Mutations on Ochratoxin A Metabolism. Toxins 14:3, pages 207.
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Rehab E. Abdelrahman, Abdel Azeim A. Khalaf, Mohamed A. Elhady, Marwa A. Ibrahim, Eman I. Hassanen & Peter A. Noshy. (2022) Quercetin ameliorates ochratoxin A-Induced immunotoxicity in broiler chickens by modulation of PI3K/AKT pathway. Chemico-Biological Interactions 351, pages 109720.
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Firas Abdul-kareem, Ahmed Ismail Al-nazzal & Ali Ameen Yaseen. (2021) Isolation, Diagnosis and Characterization of Aspergillus sp from Tea Bags Samples and Its Ability to Produce Ochratoxin A. Tikrit journal for agricultural sciences 21:3, pages 11-19.
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Shuangshuang Zhai, Yongwen Zhu, Peishi Feng, Macheng Li, Wence Wang, Lin Yang & Ye Yang. (2021) Ochratoxin A: its impact on poultry gut health and microbiota, an overview. Poultry Science 100:5, pages 101037.
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Ran Xu, Niel A. Karrow, Umesh K. Shandilya, Lv-hui Sun & Haruki Kitazawa. (2020) In-Vitro Cell Culture for Efficient Assessment of Mycotoxin Exposure, Toxicity and Risk Mitigation. Toxins 12:3, pages 146.
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S.S. Zhai, D. Ruan, Y.W. Zhu, M.C. Li, H. Ye, W.C. Wang & L. Yang. (2020) Protective effect of curcumin on ochratoxin A–induced liver oxidative injury in duck is mediated by modulating lipid metabolism and the intestinal microbiota. Poultry Science 99:2, pages 1124-1134.
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Susana Viegas, Ricardo Assunção, Magdalena Twarużek, Robert Kosicki, Jan Grajewski & Carla Viegas. (2019) Mycotoxins feed contamination in a dairy farm – potential implications for milk contamination and workers' exposure in a One Health approach. Journal of the Science of Food and Agriculture 100:3, pages 1118-1123.
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Wence Wang, Shuangshuang Zhai, Yaoyao Xia, Hao Wang, Dong Ruan, Ting Zhou, Yongwen Zhu, Hongfu Zhang, Minhong Zhang, Hui Ye, Wenkai Ren & Lin Yang. (2019) Ochratoxin A induces liver inflammation: involvement of intestinal microbiota. Microbiome 7:1.
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José Manuel Enciso, Adela López de Cerain, Laura Pastor, Amaya Azqueta & Ariane Vettorazzi. (2018) Is oxidative stress involved in the sex-dependent response to ochratoxin A renal toxicity?. Food and Chemical Toxicology 116, pages 379-387.
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Yanfei Tao, Shuyu Xie, Fanfan Xu, Aimei Liu, Yanxin Wang, Dongmei Chen, Yuanhu Pan, Lingli Huang, Dapeng Peng, Xu Wang & Zonghui Yuan. (2018) Ochratoxin A: Toxicity, oxidative stress and metabolism. Food and Chemical Toxicology 112, pages 320-331.
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V. Bunel, F. Souard, M.-H. Antoine, C. Stévigny & J.L. Nortier. 2018. Comprehensive Toxicology. Comprehensive Toxicology 340 379 .
Firdevs Mor, Omur Sengul, Senay Topsakal, Mehmet Kilic & Ozlem Ozmen. (2017) Diabetogenic Effects of Ochratoxin A in Female Rats. Toxins 9:4, pages 144.
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Peyman Akbari, Saskia Braber, Soheil Varasteh, Arash Alizadeh, Johan Garssen & Johanna Fink-Gremmels. (2016) The intestinal barrier as an emerging target in the toxicological assessment of mycotoxins. Archives of Toxicology 91:3, pages 1007-1029.
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Kathleen G. Dickman, Hans-Martin Fritsche, Arthur P. Grollman, George N. Thalmann & James Catto. 2015. Upper Tract Urothelial Carcinoma. Upper Tract Urothelial Carcinoma 1 30 .
Valeria Sorrenti, Claudia Di Giacomo, Rosaria Acquaviva, Ignazio Barbagallo, Matteo Bognanno & Fabio Galvano. (2013) Toxicity of Ochratoxin A and Its Modulation by Antioxidants: A Review. Toxins 5:10, pages 1742-1766.
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Rahul Kumar, Kausar M. Ansari, Neha Saxena, Premendra D. Dwivedi, Swatantra K. Jain & Mukul Das. (2012) Detection of Ochratoxin A in wheat samples in different regions of India. Food Control 26:1, pages 63-67.
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Bojan Jelaković, Sandra Karanović, Ivana Vuković-Lela, Frederick Miller, Karen L. Edwards, Jovan Nikolić, Karla Tomić, Neda Slade, Branko Brdar, Robert J. Turesky, Želimir Stipančić, Damir Dittrich, Arthur P. Grollman & Kathleen G. Dickman. (2012) Aristolactam-DNA adducts are a biomarker of environmental exposure to aristolochic acid. Kidney International 81:6, pages 559-567.
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Seyoung LimHyun-Jun JangJung Kuk KimJung-Min KimEun Hee ParkJun Hyuk YangYun-Hee KimKyungmoo YeaSung Ho RyuPann-Ghill Suh. (2011) Ochratoxin A Inhibits Adipogenesis Through the Extracellular Signal-Related Kinases–Peroxisome Proliferator-Activated Receptor-γ Pathway in Human Adipose Tissue-Derived Mesenchymal Stem Cells. Stem Cells and Development 20:3, pages 415-426.
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M. Marin-Kuan, V. Ehrlich, T. Delatour, C. Cavin & B. Schilter. (2011) Evidence for a Role of Oxidative Stress in the Carcinogenicity of Ochratoxin A. Journal of Toxicology 2011, pages 1-15.
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K.G. Dickman & A.P. Grollman. 2010. Comprehensive Toxicology. Comprehensive Toxicology 433 458 .
M. Herrera, A. Herrera & A. Ariño. (2009) Estimation of dietary intake of ochratoxin A from liquorice confectionery. Food and Chemical Toxicology 47:8, pages 2002-2006.
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Christophe Cavin, Thierry Delatour, Maricel Marin-Kuan, François Fenaille, Daisy Holzhäuser, Gabrièla Guignard, Claudine Bezençon, Dominique Piguet, Véronique Parisod, Janique Richoz-Payot & Benoît Schilter. (2009) Ochratoxin A–Mediated DNA and Protein Damage: Roles of Nitrosative and Oxidative Stresses. Toxicological Sciences 110:1, pages 84-94.
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Neda Slade, Ute M. Moll, Branko Brdar, Arijana Zorić & Bojan Jelaković. (2009) p53 mutations as fingerprints for aristolochic acid – an environmental carcinogen in endemic (Balkan) nephropathy. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 663:1-2, pages 1-6.
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Maricel Marin-Kuan, Christophe Cavin, Thierry Delatour & Benoît Schilter. (2008) Ochratoxin A carcinogenicity involves a complex network of epigenetic mechanisms. Toxicon 52:2, pages 195-202.
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Arthur P. Grollman, Shinya Shibutani, Masaaki Moriya, Frederick MillerLin WuUte MollNaomi Suzuki, Andrea Fernandes, Thomas Rosenquist, Zvonimir Medverec, Krunoslav JakovinaBranko BrdarNeda SladeRobert J. TureskyAngela K. GoodenoughRobert Rieger, Mato VukelićBojan Jelaković. (2007) Aristolochic acid and the etiology of endemic (Balkan) nephropathy. Proceedings of the National Academy of Sciences 104:29, pages 12129-12134.
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W. Föllmann, C. Behm & G. H. Degen. (2007) Induction of micronuclei by ochratoxin A is a sensitive parameter of its genotoxicity in cultured cells. Mycotoxin Research 23:2, pages 101-109.
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A. Ariño, M. Herrera, G. Estopañan & T. Juan. (2007) High levels of ochratoxin A in licorice and derived products. International Journal of Food Microbiology 114:3, pages 366-369.
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