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Original Articles

NovaSil clay intervention in Ghanaians at high risk for aflatoxicosis. I. Study design and clinical outcomes

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Pages 76-87 | Received 18 Dec 2006, Accepted 17 May 2007, Published online: 29 Nov 2007

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Read on this site (11)

Khurram Muaz, Muhammad Riaz, Carlos Augusto Fernandes de Oliveira, Saeed Akhtar, Shinawar Waseem Ali, Habibullah Nadeem, Sungkwon Park & Balamuralikrishnan Balasubramanian. (2022) Aflatoxin M1 in milk and dairy products: global occurrence and potential decontamination strategies. Toxin Reviews 41:2, pages 588-605.
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Abigael O. Awuor, Ellen Yard, Johnni H. Daniel, Collen Martin, Christine Bii, Amelia Romoser, Elvis Oyugi, Sarah Elmore, Samwel Amwayi, John Vulule, Nicholas C. Zitomer, Michael E. Rybak, Timothy D. Phillips, Joel M. Montgomery & Lauren S. Lewis. (2017) Evaluation of the efficacy, acceptability and palatability of calcium montmorillonite clay used to reduce aflatoxin B1 dietary exposure in a crossover study in Kenya. Food Additives & Contaminants: Part A 34:1, pages 93-102.
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Calvin C. Willhite, Nataliya A. Karyakina, Robert A. Yokel, Nagarajkumar Yenugadhati, Thomas M. Wisniewski, Ian M.F. Arnold, Franco Momoli & Daniel Krewski. (2014) Systematic review of potential health risks posed by pharmaceutical, occupational and consumer exposures to metallic and nanoscale aluminum, aluminum oxides, aluminum hydroxide and its soluble salts. Critical Reviews in Toxicology 44:sup4, pages 1-80.
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Nicole J. Mitchell, Justice Kumi, Natalie M. Johnson, Eunice Dotse, Alicia Marroquin-Cardona, Jia-Sheng Wang, Pauline E. Jolly, Nii-Ayi Ankrah & Timothy D. Phillips. (2013) Reduction in the urinary aflatoxin M1 biomarker as an early indicator of the efficacy of dietary interventions to reduce exposure to aflatoxins. Biomarkers 18:5, pages 391-398.
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Calvin C. Willhite, Gwendolyn L. Ball & Clifton J. McLellan. (2012) Total allowable concentrations of monomeric inorganic aluminum and hydrated aluminum silicates in drinking water. Critical Reviews in Toxicology 42:5, pages 358-442.
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Felicia Wu & Pornsri Khlangwiset. (2010) Evaluating the technical feasibility of aflatoxin risk reduction strategies in Africa. Food Additives & Contaminants: Part A 27:5, pages 658-676.
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L. Tang, L. Xu, E. Afriyie-Gyawu, W. Liu, P. Wang, Y. Tang, Z. Wang, H.J. Huebner, N.-A. Ankrah, D. Ofori-Adjei, J.H. Williams, J.-S. Wang & T.D. Phillips. (2009) Aflatoxin–albumin adducts and correlation with decreased serum levels of vitamins A and E in an adult Ghanaian population. Food Additives & Contaminants: Part A 26:1, pages 108-118.
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E. Afriyie-Gyawu, Z. Wang, N.-A. Ankrah, L. Xu, N.M. Johnson, L. Tang, H. Guan, H.J. Huebner, P.E. Jolly, W.O. Ellis, R. Taylor, B. Brattin, D. Ofori-Adjei, J.H. Williams, J.-S. Wang & T.D. Phillips. (2008) NovaSil clay does not affect the concentrations of vitamins A and E and nutrient minerals in serum samples from Ghanaians at high risk for aflatoxicosis. Food Additives & Contaminants: Part A 25:7, pages 872-884.
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John L. Richard. (2008) DISCOVERY OF AFLATOXINS AND SIGNIFICANT HISTORICAL FEATURES. Toxin Reviews 27:3-4, pages 171-201.
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Mohammad Nazari, Reza Heidari, Zahra Hami, Mahdi Shiri, Ehsan Nassireslami & Mohsen Chamanara. Some relevant mitigating agents of chronic aflatoxin exposure: a treatise. Drug and Chemical Toxicology 0:0, pages 1-10.
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Gilbert Kipkoech, Mercy Jepkorir, Sally Kamau, Alice Wanyoko, Susan Kibunja, Rechard Amozi Jeremiah, Johnson Masese, Vincent Ntui-Njock, Charles Mutai & Peter Mwitari. (2023) Immunomodulatory effects of aflatoxin B1 (AFB1) and the use of natural products to ameliorate its immunotoxic effects: A review. Open Research Africa 6, pages 22.
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Meichen Wang, Kelly J. Rivenbark & Timothy D. Phillips. (2022) Adsorption and detoxification of glyphosate and aminomethylphosphonic acid by montmorillonite clays. Environmental Science and Pollution Research 30:5, pages 11417-11430.
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Alicia G. Marroquín-Cardona, Youjun Deng, Jose F. Garcia-Mazcorro, Natalie M. Johnson, Nicolle J. Mitchell, Lili Tang, Jia-Sheng Wang, Roger B. Harvey & Timothy D. Phillips. (2024) Aflatoxin B 1 Sorption and Safety of Dietary Sodium Bentonite in Sprague-Dawley Rats . Clays and Clay Minerals 70:2, pages 165-181.
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Justice Kumi, Regina Appiah-Opong, Dietrich Rein, Godfred Egbi, Enoch Aninagyei, Alex Boye & Desmond Omane-Acheampong. (2022) Safety and Efficacy of Novasil Clay (Calcium Montmorillonite) in Children Exposed to Aflatoxin in Ejura-Sekyedumase District in Ghana. Global Pediatric Health 9, pages 2333794X2211212.
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Elham Jahanmard, Javad Keramat, Ali Nasirpour & Rahmatollah Emadi. (2021) Efficiency of calcined Aluminum‐Magnesium layered double hydroxide for adsorption of aflatoxin M 1 from solution and matrix of milk . Journal of Food Science 86:12, pages 5200-5212.
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Meichen Wang, Kelly Rivenbark, Joonho Gong, Fred A. Wright & Timothy D. Phillips. (2021) Application of Edible Montmorillonite Clays for the Adsorption and Detoxification of Microcystin. ACS Applied Bio Materials 4:9, pages 7254-7265.
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Blake R. Rushing & Mustafa I. Selim. (2019) Aflatoxin B1: A review on metabolism, toxicity, occurrence in food, occupational exposure, and detoxification methods. Food and Chemical Toxicology 124, pages 81-100.
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Kathy S. Xue, Guoqing Qian, Shuhan Lin, Jianjia Su, Lili Tang, Wentzel C.A. Gelderblom, Ronald T. Riley, Timothy D. Phillips & Jia-Sheng Wang. (2018) Modulation of pre-neoplastic biomarkers induced by sequential aflatoxin B1 and fumonisin B1 exposure in F344 rats treated with UPSN clay. Food and Chemical Toxicology 114, pages 316-324.
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Dilawar Hussain, Abdul Mateen & Delbert M. GatlinIIIIII. (2017) Alleviation of aflatoxin B 1 (AFB 1 ) toxicity by calcium bentonite clay: Effects on growth performance, condition indices and bioaccumulation of AFB 1 residues in Nile tilapia ( Oreochromis niloticus ). Aquaculture 475, pages 8-15.
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Veronica Ngole-Jeme & Georges-Ivo Ekosse. (2015) A Comparative Analyses of Granulometry, Mineral Composition and Major and Trace Element Concentrations in Soils Commonly Ingested by Humans. International Journal of Environmental Research and Public Health 12:8, pages 8933-8955.
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Sara Maisanaba, Silvia Pichardo, María Puerto, Daniel Gutiérrez-Praena, Ana M. Cameán & Angeles Jos. (2015) Toxicological evaluation of clay minerals and derived nanocomposites: A review. Environmental Research 138, pages 233-254.
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Nii-Ayi Ankrah, Katherine E. Zychowski, Sarah E. Elmore, Amelia A. Romoser, Justice Kumi, Nicole J. Mitchell, Timothy D. Phillips, Kristal A. Rychlik & Mildred Aleser. (2014) Short-Term Safety and Efficacy of Calcium Montmorillonite Clay (UPSN) in Children. The American Journal of Tropical Medicine and Hygiene 91:4, pages 777-785.
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A. Carraro, A. De Giacomo, M.L. Giannossi, L. Medici, M. Muscarella, L. Palazzo, V. Quaranta, V. Summa & F. Tateo. (2014) Clay minerals as adsorbents of aflatoxin M1 from contaminated milk and effects on milk quality. Applied Clay Science 88-89, pages 92-99.
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A. Marroquín-Cardona, Y. Deng, J.F. Garcia-Mazcorro, N.M. Johnson, N.J. Mitchell, L. Tang, A. Robinson, J.F. Taylor, J.-S. Wang & T.D. Phillips. (2011) Characterization and safety of uniform particle size NovaSil clay as a potential aflatoxin enterosorbent. Applied Clay Science 54:3-4, pages 248-257.
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Youjun Deng & Marek Szczerba. (2011) Computational evaluation of bonding between aflatoxin B1 and smectite. Applied Clay Science 54:1, pages 26-33.
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Lauren E. Seifert, Jack P. Davis, Joe W. Dorner, William F. Jaynes, Richard E. Zartman & Timothy H. Sanders. (2010) Value-Added Processing of Peanut Meal: Aflatoxin Sequestration during Protein Extraction. Journal of Agricultural and Food Chemistry 58:9, pages 5625-5632.
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J. F. Taylor, A. Robinson, N. Johnson, A. Marroquin-Cardona, B. Brattin, R. Taylor & T. D. Phillips. (2009) In Vitro Evaluation of Ferrihydrite as an Enterosorbent for Arsenic from Contaminated Drinking Water . Environmental Science & Technology 43:14, pages 5501-5506.
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