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Original Articles

Determination of synthetic drugs used to adulterate botanical dietary supplements using QTRAP LC-MS/MS

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Pages 595-603 | Received 01 Jul 2008, Accepted 16 Nov 2008, Published online: 24 Jun 2009

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (9)

Samin Hamidi. (2023) Assessment of Undeclared Synthetic Drugs in Dietary Supplements in an Analytical View: A Comprehensive Review. Critical Reviews in Analytical Chemistry 53:5, pages 986-996.
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Mahsa Alikord, Abdorreza Mohammadi, Marzieh Kamankesh & Nabi Shariatifar. (2022) Food safety and quality assessment: comprehensive review and recent trends in the applications of ion mobility spectrometry (IMS). Critical Reviews in Food Science and Nutrition 62:18, pages 4833-4866.
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Pengfei Jin, Shuo Xu, Wenfeng Xu, Xiaorong He, Yongmei Kuang & Xin Hu. (2020) Screening and quantification of fourteen synthetic antidiabetic adulterants in herbal pharmaceuticals and health foods by HPLC and confirmation by LC-Q-TOF-MS/MS. Food Additives & Contaminants: Part A 37:1, pages 11-18.
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João Guilherme Costa, Bojana Vidovic, Nuno Saraiva, Maria do Céu Costa, Giorgia Del Favero, Doris Marko, Nuno G. Oliveira & Ana Sofia Fernandes. (2019) Contaminants: a dark side of food supplements?. Free Radical Research 53:sup1, pages 1113-1135.
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Noortje M. Reeuwijk, Bastiaan J. Venhuis, Dries de Kaste, Ron L.A.P. Hoogenboom, Ivonne M.C.M. Rietjens & Martijn J. Martena. (2014) Active pharmaceutical ingredients detected in herbal food supplements for weight loss sampled on the Dutch market. Food Additives & Contaminants: Part A 31:11, pages 1783-1793.
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Caroline Mathon, Anita Ankli, Eike Reich, Stefan Bieri & Philippe Christen. (2014) Screening and determination of sibutramine in adulterated herbal slimming supplements by HPTLC-UV densitometry. Food Additives & Contaminants: Part A 31:1, pages 15-20.
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L.M. De Carvalho, P.A. Cohen, C.V. Silva, A.P.L. Moreira, T.M. Falcão, T.R. Dal Molin, G. Zemolin & M. Martini. (2012) A new approach to determining pharmacologic adulteration of herbal weight loss products. Food Additives & Contaminants: Part A 29:11, pages 1661-1667.
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J. Vaysse, S. Balayssac, V. Gilard, D. Desoubdzanne, M. Malet-Martino & R. Martino. (2010) Analysis of adulterated herbal medicines and dietary supplements marketed for weight loss by DOSY 1H-NMR. Food Additives & Contaminants: Part A 27:7, pages 903-916.
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Articles from other publishers (48)

Hardi Joshi, Payal Bahliwala, Jigna Vadalia & Udaykumar Vegad. (2023) Detection of synthetic lipid‐lowering adulterants in herbal products using high‐performance thin‐layer chromatography. SEPARATION SCIENCE PLUS.
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C. Maina, A. Gachanja, E. M. Kigondu, P. K. Kairigo, J. Ouma, T. Tuhkanen, J. Gichuki, L. C. Koech & R. M. Nyangacha. (2023) Simultaneous Determination of Selected Antidiabetic Pharmaceutical Drugs as Adulterants in Herbal Medicines Sold in Kenya Using Liquid Chromatography–Tandem Mass Spectrometry (LC–MS/MS). Chemistry Africa.
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A. L. Mpanyakavili, C. J. Mwankuna, F. P. Mabiki & B. Styrishave. (2022) LC–MS/MS Method for Determination of Non-opioid Analgesics Adulterants in Herbal Medicines. Chemistry Africa 5:6, pages 2149-2162.
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Ensie Hosseini, Jahan B Ghasemi & Maryam Shekarchi. (2022) Simultaneous Determination of Adulterants in Dietary Food Supplements Using Multivariate Data Analysis after Preconcentration with Novel Nanosorbents and Chromatographic Measurement. Journal of AOAC INTERNATIONAL 105:5, pages 1309-1318.
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Abdelkrim Rebiai, Bachir Ben Seghir, Hadia Hemmami, Soumeia Zeghoud, Ilham Ben Amor, Imane Kouadri, Mohammed Messaoudi, Ardalan Pasdaran, Gianluca Caruso, Somesh Sharma, Maria Atanassova & Pawel Pohl. (2022) Quality Assessment of Medicinal Plants via Chemometric Exploration of Quantitative NMR Data: A Review. Compounds 2:2, pages 163-181.
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Wadhah Atef Salem, Ehab Farouk Elkady, Marwa Ahmed Fouad & Mohammad Abdul-Azim Mohammad. (2021) Analysis of Metformin and Five Gliptins in Counterfeit Herbal Products: Designs of Experiment Screening and Optimization. Journal of AOAC INTERNATIONAL 104:6, pages 1667-1680.
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Jinmei Gao, Chunyan Ma, Qiong Duan, Wenhui Gao & Hui Li. (2021) Simultaneous Determination of 16 Illegally Added Drugs in Capsule Dietary Supplements Using a QuEChERS Method and HPLC–MS/MS. Chromatographia 84:11, pages 1009-1023.
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Erik Duiven, Luc J.C. van Loon, Laila Spruijt, Willem Koert & Olivier M. de Hon. (2021) Undeclared Doping Substances are Highly Prevalent in Commercial Sports Nutrition Supplements. Journal of Sports Science and Medicine, pages 328-338.
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Dan Osei Mensah Bonsu, Constance Afoakwah & Maria de la Paz Aguilar-Caballos. (2021) Counterfeit formulations: analytical perspective on anorectics. Forensic Toxicology 39:1, pages 1-25.
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Liliana Muschietti, Flavia Redko & Jerónimo Ulloa. (2020) Adulterants in selected dietary supplements and their detection methods. Drug Testing and Analysis 12:7, pages 861-886.
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Yogini S. Jaiswal & Leonard L. Williams. 2020. Herbal Medicine in India. Herbal Medicine in India 249 261 .
Lixia Zhang, Peng Li, Xiangfeng Bu, Jiawei Wu, Xiaolei Zhang, Bing Zhao & Yuan Tian. (2018) Combined host-guest complex with coffee-ring effect for constructing ultrasensitive SERS substrate for phenformin hydrochloride detection in healthcare products. Analytical and Bioanalytical Chemistry 410:29, pages 7599-7609.
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E. Deconinck, C. Aouadi, J.L. Bothy & P. Courselle. (2018) Detection and identification of multiple adulterants in plant food supplements using attenuated total reflectance—Infrared spectroscopy. Journal of Pharmaceutical and Biomedical Analysis 152, pages 111-119.
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Jun Ma, Rahul S. Pawar & Erich Grundel. (2018) Validation of an LC-MS/MS method for analysis of anti-diabetic drugs in botanical dietary supplements labeled for blood sugar management. Drug Testing and Analysis 10:3, pages 609-617.
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Bin bin Zhang, Yi Shi, Hui Chen, Qing xia Zhu, Feng Lu & Ying wei Li. (2018) A separable surface-enhanced Raman scattering substrate modified with MIL-101 for detection of overlapping and invisible compounds after thin-layer chromatography development. Analytica Chimica Acta 997, pages 35-43.
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Meiran Wu, Hao Li, Diya Lv & Feng Lu. (2017) Dynamic-SERS spectroscopy for the in situ discrimination of xanthine analogues in ternary mixture. Analytical and Bioanalytical Chemistry 409:23, pages 5569-5579.
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Paula Paíga, Manuela J.E. Rodrigues, Manuela Correia, Joana S. Amaral, M. Beatriz P.P. Oliveira & Cristina Delerue-Matos. (2017) Analysis of pharmaceutical adulterants in plant food supplements by UHPLC-MS/MS. European Journal of Pharmaceutical Sciences 99, pages 219-227.
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Qingxia Zhu, Mengyun Chen, Lu Han, Yongfang Yuan & Feng Lu. (2017) High efficiency screening of nine lipid-lowering adulterants in herbal dietary supplements using thin layer chromatography coupled with surface enhanced Raman spectroscopy. Analytical Methods 9:10, pages 1595-1602.
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Iwona Matraszek-Zuchowska, Barbara Wozniak & Andrzej Posyniak. (2016) Comparison of the Multiple Reaction Monitoring and Enhanced Product Ion Scan Modes for Confirmation of Stilbenes in Bovine Urine Samples Using LC–MS/MS QTRAP® System. Chromatographia 79:15-16, pages 1003-1012.
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Tiago Rocha, Joana S. Amaral & Maria Beatriz P.P. Oliveira. (2016) Adulteration of Dietary Supplements by the Illegal Addition of Synthetic Drugs: A Review. Comprehensive Reviews in Food Science and Food Safety 15:1, pages 43-62.
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Bin Hu, Yingyan Huang, Guo Yin, Gaofei Zhang, Liyang Zhang, Tiejie Wang & Zhong-Ping Yao. (2016) Rapid detection of adulterated drugs in herbal dietary supplements by wooden-tip electrospray ionization mass spectrometry. Analytical Methods 8:38, pages 6840-6846.
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Chinyere N. Nnaji, Phillip M. Mach, Jason S. Acheampong, Travis M. Falconer & Guido F. Verbeck. (2016) Analysis of trace amounts of adulterants found in powders/supplements utilizing Raman spectroscopy coupled to direct analyte-probed nanoextraction-nanospray ionization-mass spectrometry. Analytical Methods 8:24, pages 4798-4807.
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Ana Paula Lançanova Moreira, Luciana Assis Gobo, Carine Viana & Leandro Machado de Carvalho. (2016) Simultaneous analysis of antihypertensive drugs and diuretics as adulterants in herbal-based products by ultra-high performance liquid chromatography-electrospray tandem mass spectrometry. Analytical Methods 8:8, pages 1881-1888.
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N. Satheeshkumar, David Paul & A. Lingesh. 2016. Medicinal Plants - Recent Advances in Research and Development. Medicinal Plants - Recent Advances in Research and Development 73 95 .
Hao Li, Qing xia Zhu, Tsz sian Chwee, Lin Wu, Yi feng Chai, Feng Lu & Yong fang Yuan. (2015) Detection of structurally similar adulterants in botanical dietary supplements by thin-layer chromatography and surface enhanced Raman spectroscopy combined with two-dimensional correlation spectroscopy. Analytica Chimica Acta 883, pages 22-31.
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Zhe Wang, Caisheng Wu, Gangli Wang, Qingsheng Zhang & Jinlan Zhang. (2015) Novel strategy for the determination of illegal adulterants in health foods and herbal medicines using high-performance liquid chromatography with high-resolution mass spectrometry. Journal of Separation Science 38:6, pages 925-935.
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Diya Lv, Yan Cao, Ziyang Lou, Shujin Li, Xiaofei Chen, Yifeng Chai & Feng Lu. (2014) Rapid on-site detection of ephedrine and its analogues used as adulterants in slimming dietary supplements by TLC-SERS. Analytical and Bioanalytical Chemistry 407:5, pages 1313-1325.
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E. Deconinck, T. Cauwenbergh, J.L. Bothy, D. Custers, P. Courselle & J.O. De Beer. (2014) Detection of sibutramine in adulterated dietary supplements using attenuated total reflectance-infrared spectroscopy. Journal of Pharmaceutical and Biomedical Analysis 100, pages 279-283.
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Qingxia Zhu, Yongbing Cao, Yingying Cao, Yifeng Chai & Feng Lu. (2014) Rapid on-site TLC–SERS detection of four antidiabetes drugs used as adulterants in botanical dietary supplements. Analytical and Bioanalytical Chemistry 406:7, pages 1877-1884.
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Lukas Vaclavik, Alexander J. Krynitsky & Jeanne I. Rader. (2014) Targeted analysis of multiple pharmaceuticals, plant toxins and other secondary metabolites in herbal dietary supplements by ultra-high performance liquid chromatography–quadrupole-orbital ion trap mass spectrometry. Analytica Chimica Acta 810, pages 45-60.
Crossref
E. Deconinck, P.-Y. Sacre, P. Courselle & J. O. De Beer. (2013) Chromatography in the Detection and Characterization of Illegal Pharmaceutical Preparations. Journal of Chromatographic Science 51:8, pages 791-806.
Crossref
Yizhi Zhou, Xunhong Liu, Fei Chen & Fengsu Zhang. (2013) Simultaneous quantitative determination of eight index constituents and compatibility changes in Longchai Decoction by UPLC–Q-TOF-MS. Acta Pharmaceutica Sinica B 3:4, pages 281-287.
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CAI Qinren, WU Jieshan, QIAN Zhenjie, PENG Yufen, CAI Jie & DU Zhifeng. (2013) Determination of nine β-agonist residues in pig tissues by liquid chromatography-tandem mass spectrometry combining with library search. Chinese Journal of Chromatography 31:3, pages 200-205.
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Merry-Jennifer Markham & Tieraona Low Dog. 2013. Consultative Hemostasis and Thrombosis. Consultative Hemostasis and Thrombosis 595 600 .
Xiaoli Wu, Jie Liu, Jinhua Wu, Yang Wang, Cheng Xue, Ruoyu Wang, Junli Hong & Xuemin Zhou. (2012) Molecular imprinting-based micro-stir bar sorptive extraction for specific analysis of Glibenclamide in herbal dietary supplements. Journal of Separation Science 35:24, pages 3593-3599.
Crossref
Venkata Suresh Ponnuru, B.R. Challa & RamaRao Nadendla. (2012) Quantification of sibutramine and its two metabolites in human plasma by LC–ESI-MS/MS and its application in a bioequivalence study. Journal of Pharmaceutical Analysis 2:4, pages 249-257.
Crossref
E. Deconinck, K. Verlinde, P. Courselle & J.O. De Beer. (2012) A validated Ultra High Pressure Liquid Chromatographic method for the characterisation of confiscated illegal slimming products containing anorexics. Journal of Pharmaceutical and Biomedical Analysis 59, pages 38-43.
Crossref
K. Stypułkowska, A. Błażewicz, J. Maurin, K. Sarna & Z. Fijałek. (2011) X-ray powder diffractometry and liquid chromatography studies of sibutramine and its analogues content in herbal dietary supplements. Journal of Pharmaceutical and Biomedical Analysis 56:5, pages 969-975.
Crossref
Uwe Wollein, Wolfgang Eisenreich & Nicholas Schramek. (2011) Identification of novel sildenafil-analogues in an adulterated herbal food supplement. Journal of Pharmaceutical and Biomedical Analysis 56:4, pages 705-712.
Crossref
Magdalene H. Y. Tang, Sammy P. L. Chen, Sau W. Ng, Albert Y. W. Chan & Tony W. L. Mak. (2011) Case series on a diversity of illicit weight‐reducing agents: from the well known to the unexpected. British Journal of Clinical Pharmacology 71:2, pages 250-253.
Crossref
Jamie D. Dunn, Connie M. Gryniewicz-Ruzicka, John F. Kauffman, Benjamin J. Westenberger & Lucinda F. Buhse. (2011) Using a portable ion mobility spectrometer to screen dietary supplements for sibutramine. Journal of Pharmaceutical and Biomedical Analysis 54:3, pages 469-474.
Crossref
Dezső Csupor, András Szekeres, Anita Kecskeméti, Erika Vékes, Katalin Veres, Ákos Micsinay, Kálmán Szendrei & Judit Hohmann. (2010) Dietary supplements on the domestic market adulterated with sildenafil and tadalafil. Orvosi Hetilap 151:43, pages 1783-1789.
Crossref
. (2009) Current Awareness in Drug Testing and Analysis. Drug Testing and Analysis 1:11-12, pages 596-611.
Crossref
. (2009) Current literature in mass spectrometry. Journal of Mass Spectrometry 44:10, pages 1542-1553.
Crossref
Anna Lucas Mpanyakavili, Christopher Johnson Mwankuna & Faith Philemon Mabiki. (2022) Evaluation of Solid Phase Extraction and Ultrasonic Assisted Extraction Methods in Enhancing Recoveries of Non-Opioid Analgesics for LC-MS/MS Analysis in Herbal Medicines. SSRN Electronic Journal.
Crossref

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