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Research Article

Spray-dried microspheres containing ketoprofen formulated into capsules and tablets

Pages 111-121 | Published online: 29 Sep 2008

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Acarilia Eduardo Silva, Elquio Eleamen Oliveira, Monique C. Salgado Gomes, Henrique Rodrigues Marcelino, Karen C. Holanda Silva, Bartolomeu Santos Souza, Toshiyuki Nagashima$suffix/text()$suffix/text(), Alejandro Pedro Ayala, Anselmo Gomes Oliveira & Eryvaldo Sócrates Tabosa do Egito. (2013) Producing xylan/Eudragit® S100-based microparticles by chemical and physico-mechanical approaches as carriers for 5-aminosalicylic acid. Journal of Microencapsulation 30:8, pages 787-795.
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Qionghua Wei, Feifei Yang & Libiao Luan. (2013) Preparation and in vitro/in vivo evaluation of a ketoprofen orally disintegrating/sustained release tablet. Drug Development and Industrial Pharmacy 39:6, pages 928-934.
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CláudiaR. F. Souza & WanderleyP. Oliveira. (2012) Microencapsulation of Ketoprofen in Blends of Acrylic Resins by Spray Drying. Drying Technology 30:3, pages 263-275.
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Jaleh Varshosaz, Fatemeh Ahmadi, Jaber Emami, Naser Tavakoli, Mohsen Minaiyan, Parvin Mahzouni & Farid Dorkoosh. (2011) Microencapsulation of budesonide with dextran by spray drying technique for colon-targeted delivery: an in vitro/in vivo evaluation in induced colitis in rat. Journal of Microencapsulation 28:1, pages 62-73.
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Mahmoud EL-Badry, Fars K. Alanazi, Gamal M. Mahrous & Ibrahim A. Alsarra. (2010) Effects of Kollicoat IR® and hydroxypropyl-β-cyclodextrin on the dissolution rate of omeprazole from its microparticles and enteric-coated capsules. Pharmaceutical Development and Technology 15:5, pages 500-510.
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Alaa Edeen B. Yassin, Fars K. Alanazi, Mahmoud El-Badry, Ibrahim A. Alsarra, Nahla S. Barakat & Fars K. Alanazi. (2009) Preparation and Characterization of Spironolactone-Loaded Gelucire Microparticles Using Spray-Drying Technique. Drug Development and Industrial Pharmacy 35:3, pages 297-304.
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Giovanna Rassu, Elisabetta Gavini, Gianpiera Spada, Paolo Giunchedi & Salvatore Marceddu. (2008) Ketoprofen Spray-dried Microspheres Based on Eudragit® RS and RL: Study of the Manufacturing Parameters. Drug Development and Industrial Pharmacy 34:11, pages 1178-1187.
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Articles from other publishers (23)

Junqi Wu & Mark P. Andrews. (2020) Carboxylated Cellulose Nanocrystal Microbeads for Removal of Organic Dyes from Wastewater: Effects of Kinetics and Diffusion on Binding and Release. ACS Applied Nano Materials 3:11, pages 11217-11228.
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Shabnam Amanat, Somayeh Taymouri, Jaleh Varshosaz, Mohsen Minaiyan & Ardeshir Talebi. (2020) Carboxymethyl cellulose-based wafer enriched with resveratrol-loaded nanoparticles for enhanced wound healing. Drug Delivery and Translational Research 10:5, pages 1241-1254.
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Rasha A. Alshaikh, Ebtessam A. Essa & Gamal M. El Maghraby. (2019) Eutexia for enhanced dissolution rate and anti-inflammatory activity of nonsteroidal anti-inflammatory agents: Caffeine as a melting point modulator. International Journal of Pharmaceutics 563, pages 395-405.
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Paola Franco, Ernesto Reverchon & Iolanda De Marco. (2018) PVP/ketoprofen coprecipitation using supercritical antisolvent process. Powder Technology 340, pages 1-7.
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Pankaj V. Dangre, Vikesh B. Sormare & Mangesh D. Godbole. (2017) Improvement in Dissolution of Bosentan Monohydrate by Solid Dispersions Using Spray Drying Technique. Open Pharmaceutical Sciences Journal 4:1, pages 23-31.
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Luz Mary Santiago, Alex Tarancón, Héctor Bagán & José Francisco García. (2015) Production of polystyrene-based scintillation microspheres for the measurement of radioactivity by spray-drying. Journal of Radioanalytical and Nuclear Chemistry 308:3, pages 789-799.
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Faisal Usman, Ibrahim Javed, Syed Zajif Hussain, Nazar Muhammad Ranjha & Irshad Hussain. (2016) Hydrophilic nanoparticles packed in oral tablets can improve the plasma profile of short half-life hydrophobic drugs. RSC Advances 6:97, pages 94896-94904.
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Apurva R. Patel, Ravi Doddapaneni, Terrick Andey, Heather Wilson, Stephen Safe & Mandip Singh. (2015) Evaluation of self-emulsified DIM-14 in dogs for oral bioavailability and in Nu/nu mice bearing stem cell lung tumor models for anticancer activity. Journal of Controlled Release 213, pages 18-26.
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Apurva R. Patel, Chandraiah Godugu, Heather Wilson, Stephen Safe & Mandip Singh. (2015) Evaluation of Spray BIO-Max DIM-P in Dogs for Oral Bioavailability and in Nu/nu Mice Bearing Orthotopic/Metastatic Lung Tumor Models for Anticancer Activity. Pharmaceutical Research 32:7, pages 2292-2300.
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M. Pastor, A. Esquisabel, A. Talavera, G. Año, S. Fernández, B. Cedré, J.F. Infante, A. Callicó & J.L. Pedraz. (2013) An approach to a cold chain free oral cholera vaccine: in vitro and in vivo characterization of Vibrio cholerae gastro-resistant microparticles. International Journal of Pharmaceutics 448:1, pages 247-258.
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Mohamed A. Alhnan, Erfan Kidia & Abdul W. Basit. (2011) Spray-drying enteric polymers from aqueous solutions: A novel, economic, and environmentally friendly approach to produce pH-responsive microparticles. European Journal of Pharmaceutics and Biopharmaceutics 79:2, pages 432-439.
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M. El-Badry. (2011) Comparative study of preparation and characterization of enteric and enhanced release omeprazole microparticles. Journal of Drug Delivery Science and Technology 21:6, pages 491-496.
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Kristen Bowey & Ronald J. Neufeld. (2010) Systemic and Mucosal Delivery of Drugs within Polymeric Microparticles Produced by Spray Drying. BioDrugs 24:6, pages 359-377.
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Nanda Gopal Sahoo, Mitali Kakran, Lin Li & Zaher Judeh. (2010) Fabrication of composite microparticles of artemisinin for dissolution enhancement. Powder Technology 203:2, pages 277-287.
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M. Kakran, N.G. Sahoo, L. Li, Z. Judeh, Y. Wang, K. Chong & L. Loh. (2010) Fabrication of drug nanoparticles by evaporative precipitation of nanosuspension. International Journal of Pharmaceutics 383:1-2, pages 285-292.
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M. El-Badry. (2010) Improvement of the in vitro release of omeprazole from suppository bases using Kollicoat IR. Journal of Drug Delivery Science and Technology 20:5, pages 391-396.
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Nanda Gopal Sahoo, Ali Abbas, Zaher Judeh, Chang Ming Li & Kah-Hay Yuen. (2009) Solubility Enhancement of a Poorly Water-Soluble Anti-Malarial Drug: Experimental Design and Use of a Modified Multifluid Nozzle Pilot Spray Drier. Journal of Pharmaceutical Sciences 98:1, pages 281-296.
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Takuto Mizoe, Tetsuya Ozeki & Hiroaki Okada. (2008) Application of a Four-fluid Nozzle Spray Drier to Prepare Inhalable Rifampicin-containing Mannitol Microparticles. AAPS PharmSciTech 9:3, pages 755-761.
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Takuto Mizoe, Tetsuya Ozeki & Hiroaki Okada. (2007) Preparation of drug nanoparticle-containing microparticles using a 4-fluid nozzle spray drier for oral, pulmonary, and injection dosage forms. Journal of Controlled Release 122:1, pages 10-15.
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Takuto Mizoe, Shuji Beppu, Tetsuya Ozeki & Hiroaki Okada. (2007) One-step preparation of drug-containing microparticles to enhance the dissolution and absorption of poorly water-soluble drugs using a 4-fluid nozzle spray drier. Journal of Controlled Release 120:3, pages 205-210.
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Kevin J. Edgar. (2006) Cellulose esters in drug delivery. Cellulose 14:1, pages 49-64.
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Tetsuya Ozeki, Shuji Beppu, Takuto Mizoe, Yuuki Takashima, Hiroshi Yuasa & Hiroaki Okada. (2005) Preparation of two-drug composite microparticles to improve the dissolution of insoluble drug in water for use with a 4-fluid nozzle spray drier. Journal of Controlled Release 107:3, pages 387-394.
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Cheng-Shu Chaw, Cherng-Wen Tan, Yi-Yan Yang, Ling Wang & Shabbir Moochhala. (2003) Design of physostigmine-loaded polymeric microparticles for pretreatment against exposure to organophosphate agents. Biomaterials 24:7, pages 1271-1277.
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