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Research Article

Formulation and process parameters affecting protein encapsulation into PLGA microspheres during ethyl acetate-based microencapsulation process

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Pages 1-12 | Received 06 Jan 2004, Accepted 10 May 2004, Published online: 03 Oct 2008

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Read on this site (2)

BørgeN. Fredriksen, Linn Benjaminsen Hølvold, Jarl Bøgwald & RoyA. Dalmo. (2012) Optimization of Formulation Variables to Increase Antigen Entrapment in PLGA Particles. Polymer-Plastics Technology and Engineering 51:14, pages 1468-1473.
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Xue Li, Anna Radomski, Owen I Corrigan, Lidia Tajber, Fabio De Sousa Menezes, Sibylle Endter, Carlos Medina & Marek W Radomski. (2009) Platelet Compatibility of PLGA, Chitosan and PLGA–Chitosan Nanoparticles. Nanomedicine 4:7, pages 735-746.
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Articles from other publishers (15)

Heejun Park. (2024) Exploring the Effects of Process Parameters during W/O/W Emulsion Preparation and Supercritical Fluid Extraction on the Protein Encapsulation and Release Properties of PLGA Microspheres. Pharmaceutics 16:3, pages 302.
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Fangfei Hu, Jianping Qi, Yi Lu, Haisheng He & Wei Wu. (2023) PLGA-based implants for sustained delivery of peptides/proteins: Current status, challenge and perspectives. Chinese Chemical Letters 34:11, pages 108250.
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Akihiro MatsumotoMasahiro Murakami. (2023) Harmless and ecologically acceptable fabrication of long-acting injectable microspheres. Drug Discoveries & Therapeutics 17:3, pages 170-176.
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Heejun Park, Eun‐Sol Ha, Jeong‐Soo Kim & Min‐Soo Kim. (2023) Injectable sustained‐release poly(lactic‐co‐glycolic acid) (PLGA) microspheres of exenatide prepared by supercritical fluid extraction of emulsion process based on a design of experiment approach. Bioengineering & Translational Medicine 8:3.
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Abdulkareem A. Alanezi, Steven H. Neau & Anil P. D’mello. (2020) Development and Application of a Modified Method to Determine the Encapsulation Efficiency of Proteins in Polymer Matrices. AAPS PharmSciTech 21:7.
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Dwi L. Priwitaningrum, Julian Jentsch, Ruchi Bansal, Sima Rahimian, Gert Storm, Wim E. Hennink & Jai Prakash. (2020) Apoptosis-inducing peptide loaded in PLGA nanoparticles induces anti-tumor effects in vivo. International Journal of Pharmaceutics 585, pages 119535.
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Audrey Arrighi, Sarah Marquette, Claude Peerboom, Laurence Denis, Jonathan Goole & Karim Amighi. (2019) Development of PLGA microparticles with high immunoglobulin G-loaded levels and sustained-release properties obtained by spray-drying a water-in-oil emulsion. International Journal of Pharmaceutics 566, pages 291-298.
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Yi Wei, Yuxia Wang, Huixia Zhang, Weiqing Zhou & Guanghui Ma. (2016) A novel strategy for the preparation of porous microspheres and its application in peptide drug loading. Journal of Colloid and Interface Science 478, pages 46-53.
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Shalu Suri, Gang Ruan, Jessica Winter & Christine E. Schmidt. 2013. Biomaterials Science. Biomaterials Science 360 388 .
Yan Wang & Diane J. Burgess. 2012. Long Acting Injections and Implants. Long Acting Injections and Implants 167 194 .
Johannes Kluge, Francesco Fusaro, Nathalie Casas, Marco Mazzotti & Gerhard Muhrer. (2009) Production of PLGA micro- and nanocomposites by supercritical fluid extraction of emulsions: I. Encapsulation of lysozyme. The Journal of Supercritical Fluids 50:3, pages 327-335.
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Li Liu, Jian-Ping Yang, Xiao-Jie Ju, Rui Xie, Lihua Yang, Bin Liang & Liang-Yin Chu. (2009) Microfluidic preparation of monodisperse ethyl cellulose hollow microcapsules with non-toxic solvent. Journal of Colloid and Interface Science 336:1, pages 100-106.
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Kenneth Chibuzor Ofokansi, Ogbonna Okorie & Michael Umale Adikwu. (2009) Biodegradable Microspheres Based on Gelatin-Porcine Mucin Admixtures: in Vitro and in Vivo Delivery Studies. Biological and Pharmaceutical Bulletin 32:10, pages 1754-1759.
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Akihiro Matsumoto, Takeo Kitazawa, Junichi Murata, Yuji Horikiri & Hiroshi Yamahara. (2008) A novel preparation method for PLGA microspheres using non-halogenated solvents. Journal of Controlled Release 129:3, pages 223-227.
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Raghavendra C. Mundargi, V. Ramesh Babu, Vidhya Rangaswamy, Pradip Patel & Tejraj M. Aminabhavi. (2008) Nano/micro technologies for delivering macromolecular therapeutics using poly(d,l-lactide-co-glycolide) and its derivatives. Journal of Controlled Release 125:3, pages 193-209.
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