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Research Article

Investigation of the release of aspirin from spray-congealed micro-pellets

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Pages 245-251 | Received 21 Mar 2004, Accepted 10 Sep 2004, Published online: 03 Oct 2008

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Hongyi Ouyang, Soon Jun Ang, Zong Yang Lee, Tze Ning Hiew, Paul Wan Sia Heng & Lai Wah Chan. (2022) Effect of drug load and lipid–wax blends on drug release and stability from spray-congealed microparticles. Pharmaceutical Development and Technology 27:10, pages 1069-1082.
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Priscilla Chui Hong Wong, Paul Wan Sia Heng & Lai Wah Chan. (2016) A study on the solid state characteristics of spray-congealed glyceryl dibehenate solid lipid microparticles containing ibuprofen. Drug Development and Industrial Pharmacy 42:3, pages 364-377.
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Ching Mien Oh, Qiyun Guo, Paul Wan Sia Heng & Lai Wah Chan. (2014) Spray-congealed microparticles for drug delivery – an overview of factors influencing their production and characteristics. Expert Opinion on Drug Delivery 11:7, pages 1047-1060.
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Articles from other publishers (9)

Hongyi Ouyang, Annabel Shi Yin Poh, Paul Wan Sia Heng & Lai Wah Chan. (2020) Effect of Surfactants on the Melt Viscosity and Extent of Drug Embedment of Paraffin Wax Blends in Spray Congealing. Journal of Pharmaceutical Innovation 17:2, pages 414-428.
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Zehra Günel, Emine Varhan, Mehmet Koç, Ayhan Topuz & Hilal Sahin-Nadeem. (2021) Production of pungency-suppressed capsaicin microcapsules by spray chilling. Food Bioscience 40, pages 100918.
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Hongyi Ouyang, Chen Yee Ang, Paul Wan Sia Heng & Lai Wah Chan. (2019) Effects of Drug Particle Size and Lipid Additives on Drug Release from Paraffin Wax Formulations Prepared by Spray Congealing Technique. AAPS PharmSciTech 20:7.
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Hongyi Ouyang, Audrey Zheng, Paul Heng & Lai Chan. (2018) Effect of Lipid Additives and Drug on the Rheological Properties of Molten Paraffin Wax, Degree of Surface Drug Coating, and Drug Release in Spray-Congealed Microparticles. Pharmaceutics 10:3, pages 75.
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Larissa Consoli, Renato Grimaldi, Tanara Sartori, Florencia Cecilia Menegalli & Míriam Dupas Hubinger. (2016) Gallic acid microparticles produced by spray chilling technique: Production and characterization. LWT - Food Science and Technology 65, pages 79-87.
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Kenneth Chibuzor Ofokansi, Ogbonna Okorie & Michael Umale Adikwu. (2009) Biodegradable Microspheres Based on Gelatin-Porcine Mucin Admixtures: in Vitro and in Vivo Delivery Studies. Biological and Pharmaceutical Bulletin 32:10, pages 1754-1759.
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Oya Şanlı, İlker Karaca & Nuran Işıklan. (2008) Preparation, characterization, and salicylic acid release behavior of chitosan/poly(vinyl alcohol) blend microspheres. Journal of Applied Polymer Science 111:6, pages 2731-2740.
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Sreekhar Cheboyina & Christy M. Wyandt. (2008) Wax-based sustained release matrix pellets prepared by a novel freeze pelletization technique. International Journal of Pharmaceutics 359:1-2, pages 167-173.
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Kunn Hadinoto, Kewu Zhu & Reginald B.H. Tan. (2007) Drug release study of large hollow nanoparticulate aggregates carrier particles for pulmonary delivery. International Journal of Pharmaceutics 341:1-2, pages 195-206.
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