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Research Article

Preparation and characterization of ibuprofen microspheres

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Pages 529-538 | Received 03 Oct 2004, Accepted 12 Jan 2005, Published online: 03 Oct 2008

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Thaddeus H. Gugu, Geraldine C. Agu, Emmanuel M. Uronnachi & Salome A. Chime. (2023) Enhanced anti-inflammatory and ulcerogenicity of Ibuprofen microsphere formulations using Irvingia wombolu fat (IRW) and moringa oil (MO) as co-lipids. BMC Complementary Medicine and Therapies 23:1.
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Hassan El Itawi, Sami Fadlallah, Florent Allais & Patrick Perré. (2022) Green assessment of polymer microparticles production processes: a critical review. Green Chemistry 24:11, pages 4237-4269.
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Dina Ahmed, Hima Puthussery, Pooja Basnett, Jonathan C. Knowles, Sigrun Lange & Ipsita Roy. (2021) Controlled Delivery of Pan-PAD-Inhibitor Cl-Amidine Using Poly(3-Hydroxybutyrate) Microspheres. International Journal of Molecular Sciences 22:23, pages 12852.
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Yupaporn Niyom, Daniel Crespy & Adrian E. Flood. (2021) Compatibility between Drugs and Polymer in Nanoparticles Produced by the Miniemulsion‐Solvent Evaporation Technique. Macromolecular Materials and Engineering 306:7, pages 2100102.
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Paroma Arefin, Md Shehan Habib, Dipankar Chakraborty, Sreebash Chandra Bhattacharjee & Suman Das. (2021) An overview of microcapsule dosage form. International Journal of Pharmaceutical Chemistry and Analysis 7:4, pages 155-160.
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Tal Shpigel, Almog Uziel & Dan Y. Lewitus. (2018) SPHRINT – Printing Drug Delivery Microspheres from Polymeric Melts. European Journal of Pharmaceutics and Biopharmaceutics 127, pages 398-406.
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Yiping Deng, Fengjian Yang, Xiuhua Zhao, Lu Wang, Weiwei Wu, Chang Zu & Mingfang Wu. (2018) Improving the skin penetration and antifebrile activity of ibuprofen by preparing nanoparticles using emulsion solvent evaporation method. European Journal of Pharmaceutical Sciences 114, pages 293-302.
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Omar Mady. (2017) Ibuprofen Encapsulation by Eudragit RS100 as Microspheres: Preparation and Drug Release. MOJ Bioequivalence & Bioavailability 4:1.
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Paroma Arefin, Ikramul Hasan & Md. Selim Reza. (2016) Design, characterization and in vitro evaluation of HPMC K100 M CR loaded Fexofenadine HCl microspheres. SpringerPlus 5:1.
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Nootchanartch Panith, Apinya Assavanig, Sittiwat Lertsiri, Magnus Bergkvist, Rudee Surarit & Nuttawee Niamsiri. (2016) Development of tunable biodegradable polyhydroxyalkanoates microspheres for controlled delivery of tetracycline for treating periodontal disease. Journal of Applied Polymer Science 133:42.
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Ozlem Aydin, Baran Aydin, Aysen Tezcaner & Dilek Keskin. (2015) Study on physiochemical structure and in vitro release behaviors of doxycycline-loaded PCL microspheres . Journal of Applied Polymer Science 132:14, pages n/a-n/a.
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Sanjoy Kumar Das, K. Yuvaraja, Jasmina Khanam & Arunabha Nanda. (2015) Formulation development and statistical optimization of ibuprofen-loaded polymethacrylate microspheres using response surface methodology. Chemical Engineering Research and Design 96, pages 1-14.
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Praveen Kumar Gaur, Shikha Mishra & Meenakshi Bajpai. (2014) Formulation and evaluation of controlled-release of telmisartan microspheres: In vitro/in vivo study. Journal of Food and Drug Analysis 22:4, pages 542-548.
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S.A. Yehia, A.H. Elshafeey, A.N. ElMeshad & H. Al-Bialey. (2013) Formulation and évaluation of itopride microcapsules in human volunteers. Journal of Drug Delivery Science and Technology 23:3, pages 239-245.
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Bogdan C. Simionescu, Mihaela Olaru, Irina Bordianu, Cristian Ursu & Corneliu Cotofana. (2012) PVA-based hybrid composites with luminescent properties for drug delivery. High Performance Polymers 24:6, pages 449-459.
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Paz Robert, Paula García, Natalia Reyes, Jorge Chávez & José Santos. (2012) Acetylated starch and inulin as encapsulating agents of gallic acid and their release behaviour in a hydrophilic system. Food Chemistry 134:1, pages 1-8.
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Tetty Kemala, Emil Budianto & Bambang Soegiyono. (2012) Preparation and characterization of microspheres based on blend of poly(lactic acid) and poly(ɛ-caprolactone) with poly(vinyl alcohol) as emulsifier. Arabian Journal of Chemistry 5:1, pages 103-108.
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A. Sheikh Hassan, A. Sapin, A. Lamprecht, E. Emond, F. El Ghazouani & P. Maincent. (2009) Composite microparticles with in vivo reduction of the burst release effect. European Journal of Pharmaceutics and Biopharmaceutics 73:3, pages 337-344.
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Madan Mohan Kamila, Nita Mondal, Lakshmi Kanta Ghosh & Bijan Kumar Gupta. (2009) Multiunit Floating Drug Delivery System of Rosiglitazone Maleate: Development, Characterization, Statistical Optimization of Drug Release and In Vivo Evaluation. AAPS PharmSciTech 10:3.
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P. Valot, M. Baba, J.-M. Nedelec & N. Sintes-Zydowicz. (2009) Effects of process parameters on the properties of biocompatible Ibuprofen-loaded microcapsules. International Journal of Pharmaceutics 369:1-2, pages 53-63.
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S. K. Prajapati, Purnima Tripathi, Udhumansha Ubaidulla & Vikas Anand. (2008) Design and Development of Gliclazide Mucoadhesive Microcapsules: In Vitro and In Vivo Evaluation. AAPS PharmSciTech 9:1.
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