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Research Article

Fucosphere—New microsphere carriers for peptide and protein delivery: Preparation and in vitro characterization

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Pages 513-522 | Received 13 Sep 2005, Accepted 15 Dec 2005, Published online: 08 Oct 2008

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Lara L. Reys, Simone S. Silva, Diana Soares da Costa, Rui L. Reis & Tiago H. Silva. (2022) Fucoidan-based hydrogels particles as versatile carriers for diabetes treatment strategies. Journal of Biomaterials Science, Polymer Edition 33:15, pages 1939-1954.
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Ludmylla Cunha, Ana M. Rosa da Costa, João P. Lourenço, Francesca Buttini & Ana Grenha. (2018) Spray-dried fucoidan microparticles for pulmonary delivery of antitubercular drugs. Journal of Microencapsulation 35:4, pages 392-405.
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Ali Demir Sezer, Hande Kazak Sarılmışer, Erkan Rayaman, Adile Çevikbaş, Ebru Toksoy Öner & Jülide Akbuğa. (2017) Development and characterization of vancomycin-loaded levan-based microparticular system for drug delivery. Pharmaceutical Development and Technology 22:5, pages 627-634.
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Tiago H. Silva, Anabela Alves, Elena G. Popa, Lara L. Reys, Manuela E. Gomes, Rui A. Sousa, Simone S. Silva, João F. Mano & Rui L. Reis. (2012) Marine algae sulfated polysaccharides for tissue engineering and drug delivery approaches. Biomatter 2:4, pages 278-289.
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Ali Demir Sezer & Jülide Akbuğa. (2012) The design of biodegradable ofloxacin-based core-shell microspheres: Influence of the formulation parameters on in vitro characterization. Pharmaceutical Development and Technology 17:1, pages 118-124.
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StanislavR. Khil’chenko, TatianaS. Zaporozhets, NataliaM. Shevchenko, TatianaN. Zvyagintseva, Uwe Vogel, Peter Seeberger & Bernd Lepenies. (2011) Immunostimulatory Activity of Fucoidan from the Brown Alga Fucus evanescens: Role of Sulfates and Acetates. Journal of Carbohydrate Chemistry 30:4-6, pages 291-305.
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Alcina M. M. B. Morais, Ana Alves, Decha Kumla & Rui M. S. C. Morais. 2020. Polysaccharides of Microbial Origin. Polysaccharides of Microbial Origin 1 28 .
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Mina Jafari, Vishnu Sriram, Zhenyuan Xu, Greg M. Harris & Joo-Youp Lee. (2020) Fucoidan-Doxorubicin Nanoparticles Targeting P-Selectin for Effective Breast Cancer Therapy. Carbohydrate Polymers 249, pages 116837.
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S. R. Khil'chenko, T. S. Zaporozhets, T. N. Zvyagintseva, N. M. Shevchenko & N. N. Besednov. (2020) The Role of Sulfates in Fucoidan Extracted from Fucus evanescens in Proinflammatory Cytokines Production by Human Peripheral Blood Cells in vitro. Antibiotics and Chemotherapy 65:5-6, pages 3-10.
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Gopi Suresh Oggu, Surekha Velidandla, Kranti Kiran Reddy Ealla, Jayachandran Venkatesan, Amit Asthana, Se‐Kwon Kim & Ira Bhatnagar. 2020. Encyclopedia of Marine Biotechnology. Encyclopedia of Marine Biotechnology 1209 1229 .
Lara L. Reys, Simone S. Silva, Catarina Oliveira, Rita Lopez‐Cebral, Nuno M. Neves, Albino Martins, Joaquim M. Oliveira, Tiago H. Silva & Rui L. Reis. 2020. Encyclopedia of Marine Biotechnology. Encyclopedia of Marine Biotechnology 2619 2650 .
Natalya V. Krylova, Svetlana P. Ermakova, Vyacheslav F. Lavrov, Irina A. Leneva, Galina G. Kompanets, Olga V. Iunikhina, Marina N. Nosik, Linna K. Ebralidze, Irina N. Falynskova, Artem S. Silchenko & Tatyana S. Zaporozhets. (2020) The Comparative Analysis of Antiviral Activity of Native and Modified Fucoidans from Brown Algae Fucus evanescens In Vitro and In Vivo. Marine Drugs 18:4, pages 224.
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Cláudia Nunes & Manuel A. Coimbra. (2019) The Potential of Fucose-Containing Sulfated Polysaccharides As Scaffolds for Biomedical Applications. Current Medicinal Chemistry 26:35, pages 6399-6411.
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Viktoria Evgenievna Suprunchuk. (2019) Low-molecular-weight fucoidan: Chemical modification, synthesis of its oligomeric fragments and mimetics. Carbohydrate Research 485, pages 107806.
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Aleksandra Citkowska, Marta Szekalska & Katarzyna Winnicka. (2019) Possibilities of Fucoidan Utilization in the Development of Pharmaceutical Dosage Forms. Marine Drugs 17:8, pages 458.
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Göran Roos, Anthony Cheshire, Sasi Nayar, Steven M. Clarke & Wei ZhangSasi Nayar, Wei Zhang & Göran Roos. 2019. Harnessing Marine Macroalgae for Industrial Purposes in an Australian Context. Harnessing Marine Macroalgae for Industrial Purposes in an Australian Context 22 109 .
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Lucas Chollet, Pierre Saboural, Cédric Chauvierre, Jean-Noël Villemin, Didier Letourneur & Frédéric Chaubet. (2016) Fucoidans in Nanomedicine. Marine Drugs 14:8, pages 145.
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Lara L. Reys, Simone S. Silva, Diana Soares da Costa, Nuno M. Oliveira, João F. Mano, Rui L. Reis & Tiago H. Silva. (2016) Fucoidan Hydrogels Photo-Cross-Linked with Visible Radiation As Matrices for Cell Culture. ACS Biomaterials Science & Engineering 2:7, pages 1151-1161.
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Ludmylla Cunha & Ana Grenha. (2016) Sulfated Seaweed Polysaccharides as Multifunctional Materials in Drug Delivery Applications. Marine Drugs 14:3, pages 42.
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Matias Cardoso, Rui Costa & João Mano. (2016) Marine Origin Polysaccharides in Drug Delivery Systems. Marine Drugs 14:2, pages 34.
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Ndidi Chinyelu Ngwuluka & Nelson Ochekpe. 2015. Encyclopedia of Biomedical Polymers and Polymeric Biomaterials. Encyclopedia of Biomedical Polymers and Polymeric Biomaterials 5603 5618 .
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Sehyun Park, Sunae Hwang & Jonghwi Lee. (2011) pH-responsive hydrogels from moldable composite microparticles prepared by coaxial electro-spray drying. Chemical Engineering Journal 169:1-3, pages 348-357.
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Nils Carlsson, Annika Borde, Sebastian Wölfel, Björn Åkerman & Anette Larsson. (2011) Quantification of protein concentration by the Bradford method in the presence of pharmaceutical polymers. Analytical Biochemistry 411:1, pages 116-121.
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Ali Demir Sezer, Hande Kazak, Ebru Toksoy Öner & Jülide Akbuğa. (2011) Levan-based nanocarrier system for peptide and protein drug delivery: Optimization and influence of experimental parameters on the nanoparticle characteristics. Carbohydrate Polymers 84:1, pages 358-363.
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Ali Demir Sezer & Erdal Cevher. 2011. Active Implants and Scaffolds for Tissue Regeneration. Active Implants and Scaffolds for Tissue Regeneration 377 406 .
Ali Demir Sezer & Jülide Akbuğa. (2009) Comparison on In Vitro Characterization of Fucospheres and Chitosan Microspheres Encapsulated Plasmid DNA (pGM-CSF): Formulation Design and Release Characteristics. AAPS PharmSciTech 10:4, pages 1193-1199.
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Enrique Muñoz Tavera, Shyam B. Kadali, Hitesh G. Bagaria, Amy W. Liu & Michael S. Wong. (2009) Experimental and modeling analysis of diffusive release from single‐shell microcapsules. AIChE Journal 55:11, pages 2950-2965.
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A.D. Sezer, E. Cevher, F. Hatipoğlu, Z. Oğurtan, A.L. Baş & J. Akbuğa. (2008) The use of fucosphere in the treatment of dermal burns in rabbits. European Journal of Pharmaceutics and Biopharmaceutics 69:1, pages 189-198.
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