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Research Article

Preparation and evaluation of biodegradable flubiprofen gelatin micro-spheres for intra-articular administration

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Pages 515-524 | Received 23 Jun 2006, Accepted 03 May 2007, Published online: 08 Oct 2008

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Laurent Bédouet, Florentina Pascale, Michel Bonneau & Alexandre Laurent. (2015) In vitro evaluation of S-(+)-ibuprofen as drug candidate for intra-articular drug delivery system. Drug Development and Industrial Pharmacy 41:1, pages 85-94.
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Jitendra Kawadkar, Ritika Jain, Raj Kishore, Ashwinkumar Pathak & Meenakshi Kanwar Chauhan. (2013) Formulation and evaluation of flurbiprofen-loaded genipin cross-linked gelatin microspheres for intra-articular delivery. Journal of Drug Targeting 21:2, pages 200-210.
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Helen M Burt, Antonia Tsallas, Samuel Gilchrist & Linda S Liang. (2009) Intra-articular drug delivery systems: overcoming the shortcomings of joint disease therapy. Expert Opinion on Drug Delivery 6:1, pages 17-26.
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Michael D VanAuker & Elizabeth Hood. (2008) Delivery strategies to target therapies to inflammatory tissue. Expert Opinion on Drug Delivery 5:7, pages 767-774.
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Patrícia A. Coimbra, Hermínio C. De Sousa & Maria H. Gil. (2008) Preparation and characterization of flurbiprofen-loaded poly(3-hydroxybutyrate-co-3-hydroxyvalerate) microspheres. Journal of Microencapsulation 25:3, pages 170-178.
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Articles from other publishers (15)

Hemant Singh, Aniruddha Dan, Mukesh Kumar Kumawat, Vaishali Pawar, Deepak S. Chauhan, Ajeet Kaushik, Dhiraj Bhatia, Rohit Srivastava & Mukesh Dhanka. (2023) Pathophysiology to advanced intra-articular drug delivery strategies: Unravelling rheumatoid arthritis. Biomaterials 303, pages 122390.
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Sheng-Long Ding, Xin Liu, Xi-Yuan Zhao, Ke-Tao Wang, Wei Xiong, Zi-Li Gao, Cheng-Yi Sun, Min-Xuan Jia, Cheng Li, Qi Gu & Ming-Zhu Zhang. (2022) Microcarriers in application for cartilage tissue engineering: Recent progress and challenges. Bioactive Materials 17, pages 81-108.
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Sarah E. Mailhiot, Matthew A. Thompson, Akiko E. Eguchi, Sabrina E. Dinkel, Martin K. Lotz, Steven F. Dowdy & Ronald K. June. (2020) The TAT Protein Transduction Domain as an Intra-Articular Drug Delivery Technology. CARTILAGE 13:2_suppl, pages 1637S-1645S.
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Shamsul Bin Sulaiman, Ruszymah Binti Haji Idrus & Ng Min Hwei. (2020) Gelatin Microsphere for Cartilage Tissue Engineering: Current and Future Strategies. Polymers 12:10, pages 2404.
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Hend Abd-Allah, Amany O. Kamel & Omaima A. Sammour. (2016) Injectable long acting chitosan/tripolyphosphate microspheres for the intra-articular delivery of lornoxicam: Optimization and in vivo evaluation. Carbohydrate Polymers 149, pages 263-273.
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Taylor E. Kavanaugh, Thomas A. Werfel, Hongsik Cho, Karen A. Hasty & Craig L. Duvall. (2015) Particle-based technologies for osteoarthritis detection and therapy. Drug Delivery and Translational Research 6:2, pages 132-147.
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Xiaole Qi, Xiaoxue Qin, Rong Yang, Jiayi Qin, Wenyan Li, Kun Luan, Zhenghong Wu & Li Song. (2016) Intra-articular Administration of Chitosan Thermosensitive In Situ Hydrogels Combined With Diclofenac Sodium–Loaded Alginate Microspheres. Journal of Pharmaceutical Sciences 105:1, pages 122-130.
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Maarten Janssen, George Mihov, Tim Welting, Jens Thies & Pieter Emans. (2014) Drugs and Polymers for Delivery Systems in OA Joints: Clinical Needs and Opportunities. Polymers 6:3, pages 799-819.
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Laurent Bédouet, Laurence Moine, Florentina Pascale, Van-Nga Nguyen, Denis Labarre & Alexandre Laurent. (2014) Synthesis of hydrophilic intra-articular microspheres conjugated to ibuprofen and evaluation of anti-inflammatory activity on articular explants. International Journal of Pharmaceutics 459:1-2, pages 51-61.
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Laurent Bédouet, Florentina Pascale, Laurence Moine, Michel Wassef, Saïda H. Ghegediban, Van-Nga Nguyen, Michel Bonneau, Denis Labarre & Alexandre Laurent. (2013) Intra-articular fate of degradable poly(ethyleneglycol)-hydrogel microspheres as carriers for sustained drug delivery. International Journal of Pharmaceutics 456:2, pages 536-544.
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Jitendra Kawadkar & Meenakshi Kanwar Chauhan. (2012) Intra-articular delivery of genipin cross-linked chitosan microspheres of flurbiprofen: Preparation, characterization, in vitro and in vivo studies. European Journal of Pharmaceutics and Biopharmaceutics 81:3, pages 563-572.
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J. Pradal, O. Jordan & E. Allémann. (2012) Intra-articular drug delivery for arthritis diseases: the value of extended release and targeting strategies. Journal of Drug Delivery Science and Technology 22:5, pages 409-419.
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Scott H.R. Edwards. (2011) Intra-articular drug delivery: The challenge to extend drug residence time within the joint. The Veterinary Journal 190:1, pages 15-21.
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Heidi M. Mansour, MinJi Sohn, Abeer Al-Ghananeem & Patrick P. DeLuca. (2010) Materials for Pharmaceutical Dosage Forms: Molecular Pharmaceutics and Controlled Release Drug Delivery Aspects. International Journal of Molecular Sciences 11:9, pages 3298-3322.
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Neethu Mohan, Prabha D. Nair & Yasuhiko Tabata. (2008) A 3D biodegradable protein based matrix for cartilage tissue engineering and stem cell differentiation to cartilage. Journal of Materials Science: Materials in Medicine 20:S1, pages 49-60.
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