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Research Article

Formulation, in vitro evaluation and kinetic analysis of chitosan–gelatin bilayer muco-adhesive buccal patches of insulin nanoparticles

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Pages 613-624 | Received 01 Feb 2016, Accepted 05 Sep 2016, Published online: 05 Oct 2016

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Nusaiba K. Al-Nemrawi, Sara S. M. Alsharif, Karem H. Alzoubi & Rami Q. Alkhatib. (2019) Preparation and characterization of insulin chitosan-nanoparticles loaded in buccal films. Pharmaceutical Development and Technology 24:8, pages 967-974.
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Muhammet Davut Arpa, Neslihan Üstündağ Okur, Mehmet Koray Gök, Saadet Özgümüş & Erdal Cevher. (2023) Chitosan-based buccal mucoadhesive patches to enhance the systemic bioavailability of tizanidine. International Journal of Pharmaceutics 642, pages 123168.
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Nimisha Srivastava & Sahifa Aslam. (2022) Recent Advancements and Patents on Buccal Drug Delivery Systems: A Comprehensive Review. Recent Patents on Nanotechnology 16:4, pages 308-325.
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Diaa Al-Domi, Ayat Bozeya & Mohamed Al-Fandi. (2022) Development of an Insulin Nano-delivery System through Buccal Administration. Current Drug Delivery 19:8, pages 889-901.
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Gustavo Moraes, Carolina Zambom & Walter L. Siqueira. (2021) Nanoparticles in Dentistry: A Comprehensive Review. Pharmaceuticals 14:8, pages 752.
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Marija Jovanović, Nataša Tomić, Sandra Cvijić, Dušica Stojanović, Svetlana Ibrić & Petar Uskoković. (2021) Mucoadhesive Gelatin Buccal Films with Propranolol Hydrochloride: Evaluation of Mechanical, Mucoadhesive, and Biopharmaceutical Properties. Pharmaceutics 13:2, pages 273.
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Guilherme T. Voss, Matheus S. Gularte, Renata L. de Oliveira, Cristiane Luchese, André R. Fajardo & Ethel A. Wilhelm. (2020) Biopolymeric films as delivery vehicles for controlled release of hydrocortisone: Promising devices to treat chronic skin diseases. Materials Science and Engineering: C 114, pages 111074.
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Adebanji Joseph Olasupo Oluwole, Daniel Imwansi Ikhu-Omoregbe & Victoria Adaora Jideani. (2020) Physicochemical Properties of African Catfish Mucus and Its Effect on the Stability of Soya Milk Emulsions. Applied Sciences 10:3, pages 916.
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Andrea C. Ortiz & Javier O. Morales. 2020. Mucosal Delivery of Drugs and Biologics in Nanoparticles. Mucosal Delivery of Drugs and Biologics in Nanoparticles 107 124 .
Susan Hua. (2019) Advances in Nanoparticulate Drug Delivery Approaches for Sublingual and Buccal Administration. Frontiers in Pharmacology 10.
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Zahra Mahdizadeh Barzoki, Zahra Emam-Djomeh, Elaheh Mortazavian, Niyousha Rafiee-Tehrani, Homa Behmadi, Morteza Rafiee-Tehrani & Ali Akbar Moosavi-Movahedi. (2018) Determination of diffusion coefficient for released nanoparticles from developed gelatin/chitosan bilayered buccal films. International Journal of Biological Macromolecules 112, pages 1005-1013.
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Mario Jug, Anita Hafner, Jasmina Lovrić, Maja Lusina Kregar, Ivan Pepić, Željka Vanić, Biserka Cetina-Čižmek & Jelena Filipović-Grčić. (2018) An overview of in vitro dissolution/release methods for novel mucosal drug delivery systems. Journal of Pharmaceutical and Biomedical Analysis 147, pages 350-366.
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