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Original Articles

Development of levosulpiride-loaded solid lipid nanoparticles and their in vitro and in vivo comparison with commercial product

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Pages 160-169 | Received 31 Jul 2019, Accepted 23 Dec 2019, Published online: 17 Jan 2020

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (8)

Xuemei Luo, Aiman Saleem, Uswa Shafique, Sadia Sarwar, Kalim Ullah, Muhammad Imran, Alam Zeb & Fakhar ud Din. (2023) Rivaroxaban-loaded SLNs with treatment potential of deep vein thrombosis: in-vitro, in-vivo, and toxicity evaluation. Pharmaceutical Development and Technology 28:7, pages 625-637.
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Touseef Nawaz, Muhammad Iqbal, Barkat Ali Khan, Naveed Ahmed, Asif Nawaz, Akhtar Rasul, Waleed Y. Rizg, Abdulmajeed M. Jali, Rayan A. Ahmed & Awaji Y. Safhi. (2022) Polycaprolactone based pharmaceutical nanoemulsion loaded with acriflavine: optimization and in vivo burn wound healing activity. Drug Delivery 29:1, pages 3233-3244.
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Hezhong Ouyang, Jinquan Hu, XingYing Qiu, Shaochang Wu, Fudong Guo & Youguo Tan. (2022) Improved biopharmaceutical performance of antipsychotic drug using lipid nanoparticles via intraperitoneal route. Pharmaceutical Development and Technology 27:7, pages 853-863.
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Guo Yu, Zakir Ali, Anam Sajjad Khan, Kalim Ullah, Humzah Jamshaid, Alam Zeb, Muhammad Imran, Sadia Sarwar, Han-Gon Choi & Fakhar ud Din. (2021) RETRACTED ARTICLE: Preparation, Pharmacokinetics, and Antitumor Potential of Miltefosine-Loaded Nanostructured Lipid Carriers. International Journal of Nanomedicine 16, pages 3255-3273.
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Sibgha Batool, Fatima Zahid, Fakhar- Ud-Din, Syeda Sohaila Naz, Muhammad Junaid Dar, Muhammad Waseem Khan, Alam Zeb & Gul Majid Khan. (2021) Macrophage targeting with the novel carbopol-based miltefosine-loaded transfersomal gel for the treatment of cutaneous leishmaniasis: in vitro and in vivo analyses. Drug Development and Industrial Pharmacy 47:3, pages 440-453.
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Articles from other publishers (25)

Muhammad Jawad, Uswa Shafique, Fakhar ud Din, Ainy Butt, Salman Khan, Gul Majid Khan, Ali H. Alamri, Ahmed A. Lahiq, Shaker T. Alsharif & Khulod S. Almerai. (2024) Nose to brain delivery of escitalopram-loaded nano-structured lipid carriers thermosensitive gel: Formulation, physiochemical, pharmacokinetic and pharmacodynamics evaluation. Journal of Drug Delivery Science and Technology 97, pages 105800.
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Mao Li, Gang Fang, Fatima Zahid, Raheela Saleem, Ghazala Ishrat, Zakir Ali, Muhammad Naeem & Fakhar ud Din. (2024) Co-delivery of paclitaxel and curcumin loaded solid lipid nanoparticles for improved targeting of lung cancer: In vitro and in vivo investigation. Heliyon 10:9, pages e30290.
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Sachin Dattram Pawar, Komal Gawali, Sandeep Jat, Pooja Singh, Ashok Kumar Datusalia, Hitesh Kulhari & Pramod Kumar. (2024) Physiochemical characterization and pharmacokinetic assessment of Bergamottin solid lipid nanoparticles. Journal of Drug Delivery Science and Technology 93, pages 105426.
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Jingyu Ren, Tao Liu, Bo Bi, Saba Sohail & Fakhar ud Din. (2024) Development and Evaluation of Tacrolimus Loaded Nano-Transferosomes for Skin Targeting and Dermatitis Treatment. Journal of Pharmaceutical Sciences 113:2, pages 471-485.
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Aiman Saleem, Fakhar ud Din, Zakir Ali, Fatima Zahid, Ali H. Alamri, Ahmed A. Lahiq, Taha Alqahtani & Hanan M. Alharbi. (2024) Development and evaluation of regorafenib loaded liquid suppository for rectal delivery: In vitro, in vivo analyses. Journal of Drug Delivery Science and Technology 91, pages 105239.
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Hadiqa Nazish Raja, Fakhar ud Din, Kanwal Shabbir, Salman Khan, Ali H. Alamri, Ahmed Abdullah Al Awadh, Ahmed A. Lahiq & Ali Alasiri. (2023) Sodium alginate-based smart gastro-retentive drug delivery system of revaprazan loaded SLNs; Formulation and characterization. International Journal of Biological Macromolecules 253, pages 127402.
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Sidra Bashir, Kanwal Shabbir, Fakhar ud Din, Saif Ullah Khan, Zakir Ali, Barkat Ali Khan, Dong Wuk Kim & Gul Majid Khan. (2023) Nitazoxanide and quercetin co-loaded nanotransfersomal gel for topical treatment of cutaneous leishmaniasis with macrophage targeting and enhanced anti-leishmanial effect. Heliyon 9:11, pages e21939.
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Pushkaraj Wagh, Jonathan Moreno, Christopher Nayar & Jeffrey Wang. 2023. Oral Bioavailability and Drug Delivery. Oral Bioavailability and Drug Delivery 575 590 .
Yan Jiao, Shijing Xie, Abdul Baseer & Fakhar Ud-din. (2023) Rectal Administration of Celecoxib Liquid Suppositories with Enhanced Bioavailability and Safety in Rats. Current Drug Delivery 20:2, pages 201-210.
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Humzah Jamshaid, Fakhar ud Din, Kainat Nousheen, Saif Ullah Khan, Anam Fatima, Salman Khan, Han Gon Choi & Gul Majid Khan. (2023) Mannosylated imiquimod-terbinafine co-loaded transethosomes for cutaneous leishmaniasis; assessment of its anti-leishmanial potential, in vivo safety and immune response modulation. Biomaterials Advances 145, pages 213266.
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Summaira Maqsood, Fakhar Ud Din, Saif Ullah Khan, Ehsan Elahi, Zakir Ali, Humzah Jamshaid, Alam Zeb, Tunazza Nadeem, Wajed Ahmed, Salman Khan & Han Gon Choi. (2022) Levosulpiride-loaded nanostructured lipid carriers for brain delivery with antipsychotic and antidepressant effects. Life Sciences 311, pages 121198.
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Zakir Ali, Fakhar ud Din, Fatima Zahid, Saba Sohail, Basalat Imran, Salman Khan, Maimoona Malik, Alam Zeb & Gul Majid Khan. (2022) RETRACTED ARTICLE: Transdermal delivery of allopurinol-loaded nanostructured lipid carrier in the treatment of gout. BMC Pharmacology and Toxicology 23:1.
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Basalat Imran, Fakhar ud Din, Zakir Ali, Anam Fatima, Muhammad Waseem Khan, Dong Wuk Kim, Maimoona Malik, Saba Sohail, Sibgha Batool, Muhammad Jawad, Kanwal Shabbir, Alam Zeb & Barkat Ali Khan. (2022) Statistically designed dexibuprofen loaded solid lipid nanoparticles for enhanced oral bioavailability. Journal of Drug Delivery Science and Technology 77, pages 103904.
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Sadia Tabassam Arif, Shahiq uz Zaman, Muhammad Ayub Khan, Tanveer A. Tabish, Muhammad Farhan Sohail, Rabia Arshad, Jin-Ki Kim & Alam Zeb. (2022) Augmented Oral Bioavailability and Prokinetic Activity of Levosulpiride Delivered in Nanostructured Lipid Carriers. Pharmaceutics 14:11, pages 2347.
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Husna Khalid, Sibgha Batool, Fakhar ud Din, Salman Khan & Gul Majid Khan. (2022) Macrophage targeting of nitazoxanide-loaded transethosomal gel in cutaneous leishmaniasis. Royal Society Open Science 9:10.
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Zhonghua Guo, Ping Qi, Donghong Pei & Xiuju Zhang. (2022) Raloxifene-loaded solid lipid nanoparticles decorated gel with enhanced treatment potential of osteoporosis. Journal of Drug Delivery Science and Technology 75, pages 103733.
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Maryam Bibi, Fakhar ud Din, Yasir Anwar, Naser A. Alkenani, Ali T. Zari, Muhammad Mukhtiar, Isam M. Abu Zeid, Eman Hilal Althubaiti, Hadiqa Nazish, Alam Zeb, Izhar Ullah, Gul Majid Khan & Han-Gon Choi. (2022) Cilostazol-loaded solid lipid nanoparticles: Bioavailability and safety evaluation in an animal model. Journal of Drug Delivery Science and Technology 74, pages 103581.
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Atif Ullah Khan, Humzah Jamshaid, Fakhar ud Din, Alam Zeb & Gul Majid Khan. (2022) Designing, Optimization and Characterization of Trifluralin Transfersomal Gel to Passively Target Cutaneous Leishmaniasis. Journal of Pharmaceutical Sciences 111:6, pages 1798-1811.
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Rukhshanda Habib, Abul Kalam Azad, Muhammad Akhlaq, Fakhria A. Al-Joufi, Gul Shahnaz, Hanan R. H. Mohamed, Muhammad Naeem, Abdulraheem S. A. Almalki, Junaid Asghar, Aamir Jalil & Mohamed M. Abdel-Daim. (2022) Thiolated Chitosan Microneedle Patch of Levosulpiride from Fabrication, Characterization to Bioavailability Enhancement Approach. Polymers 14:3, pages 415.
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Awais Mushtaq, Abdul Baseer, Syed Saoud Zaidi, Muhammad Waseem Khan, Sajiha Batool, Ehsan Elahi, Waqar Aman, Muhammad Naeem & Fakhar ud Din. (2022) Fluconazole-loaded thermosensitive system: In vitro release, pharmacokinetics and safety study. Journal of Drug Delivery Science and Technology 67, pages 102972.
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A. Alper Öztürk & Cordin Arpagaus. (2021) Nano Spray-Dried Drugs for Oral Administration: A Review. ASSAY and Drug Development Technologies 19:7, pages 412-441.
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Gulen Melike Demirbolat, Goknil Pelin Coskun, Omer Erdogan & Ozge Cevik. (2021) Long chain fatty acids can form aggregates and affect the membrane integrity. Colloids and Surfaces B: Biointerfaces 204, pages 111795.
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R. Xing, O. Mustapha, T. Ali, M. Rehman, S. S. Zaidi, A. Baseer, S. Batool, M. Mukhtiar, S. Shafique, M. Malik, S. Sohail, Z. Ali, F. Zahid, A. Zeb, F. Shah, A. Yousaf & F. Din. (2021) Development, Characterization, and Evaluation of SLN-Loaded Thermoresponsive Hydrogel System of Topotecan as Biological Macromolecule for Colorectal Delivery. BioMed Research International 2021, pages 1-14.
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Fakhar ud Din, Sung Giu Jin & Han-Gon Choi. (2021) Particle and Gel Characterization of Irinotecan-Loaded Double-Reverse Thermosensitive Hydrogel. Polymers 13:4, pages 551.
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Anam Sajjad Khan, Fakhar ud Din, Zakir Ali, Maryam Bibi, Fatima Zahid, Alam Zeb, Mujeeb-ur-Rehman & Gul Majid Khan. (2021) Development, in vitro and in vivo evaluation of miltefosine loaded nanostructured lipid carriers for the treatment of Cutaneous Leishmaniasis. International Journal of Pharmaceutics 593, pages 120109.
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