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Research Article

Thermosensitivity of multidrug-resistant human gastric and pancreatic carcinoma cells

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Pages 291-303 | Published online: 09 Jul 2009

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Julian Palzer, Benedikt Mues, Richard Goerg, Merel Aberle, Sander S Rensen, Steven W M Olde Damink, Rianne D W Vaes, Thorsten Cramer, Thomas Schmitz-Rode, Ulf P Neumann, Ioana Slabu & Anjali A Roeth. (2021) Magnetic Fluid Hyperthermia as Treatment Option for Pancreatic Cancer Cells and Pancreatic Cancer Organoids. International Journal of Nanomedicine 16, pages 2965-2981.
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Ibrahim M El-Sherbiny, Nancy M Elbaz, Mohammed Sedki, Abdulaziz Elgammal & Magdi H Yacoub. (2017) Magnetic nanoparticles-based Drug and Gene Delivery Systems for the Treatment of Pulmonary Diseases. Nanomedicine 12:4, pages 387-402.
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Toshihiko Torigoe, Yoshihiko Hirohashi, Kazuyo Yasuda & Noriyuki Sato. (2013) Constitutive expression and activation of stress response genes in cancer stem-like cells/tumour initiating cells: Potent targets for cancer stem cell therapy. International Journal of Hyperthermia 29:5, pages 436-441.
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Faraz Chamani, Marla M. Pyle, Tej B. Shrestha, Jan Sebek, Stefan H. Bossmann, Matthew T. Basel, Rahul A. Sheth & Punit Prakash. (2023) In Vitro Measurement and Mathematical Modeling of Thermally-Induced Injury in Pancreatic Cancer Cells. Cancers 15:3, pages 655.
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Hailei Lin, Liangliang Yin, Beidong Chen & Yanqin Ji. (2022) Design of functionalized magnetic silica multi-core composite nanoparticles for synergistic magnetic hyperthermia/radiotherapy in cancer cells. Colloids and Surfaces B: Biointerfaces 219, pages 112814.
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Maohua Huang, Minfeng Chen, Wencai Ye & Dongmei Zhang. 2019. Protein Kinase Inhibitors as Sensitizing Agents for Chemotherapy. Protein Kinase Inhibitors as Sensitizing Agents for Chemotherapy 29 43 .
Sonja L. B. Arneaud & Peter M. Douglas. (2016) The stress response paradox: fighting degeneration at the cost of cancer. The FEBS Journal 283:22, pages 4047-4055.
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Sylwia Borska, Monika Pedziwiatr, Monika Danielewicz, Katarzyna Nowinska, Bartosz Pula, Malgorzata Drag-Zalesinska, Mateusz Olbromski, Agnieszka Gomulkiewicz & Piotr Dziegiel. (2016) Classical and atypical resistance of cancer cells as a target for resveratrol. Oncology Reports 36:3, pages 1562-1568.
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Marc Hemmer, Sören Krawczyk, Ina Simon, Hermann Lage & Andreas Hilgeroth. (2015) Discovery of substituted 1,4-dihydroquinolines as novel class of ABCB1 modulators. Bioorganic & Medicinal Chemistry 23:15, pages 5015-5021.
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Mariana A. Reis, Angela Paterna, Ricardo J. Ferreira, Hermann Lage & Maria-José U. Ferreira. (2014) Macrocyclic diterpenes resensitizing multidrug resistant phenotypes. Bioorganic & Medicinal Chemistry 22:14, pages 3696-3702.
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Ling-Yun Zhao, Jia-Yi Liu, Wei-Wei Ouyang, Dan-Ye Li, Li Li, Li-Ya Li & Jin-Tian Tang. (2013) Magnetic-mediated hyperthermia for cancer treatment: Research progress and clinical trials. Chinese Physics B 22:10, pages 108104.
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Claudius Coburger, Hermann Lage, Joséf Molnár, Andreas Langner & Andreas Hilgeroth. (2010) Multidrug resistance reversal properties and cytotoxic evaluation of representatives of a novel class of HIV-1 protease inhibitors. Journal of Pharmacy and Pharmacology 62:12, pages 1704-1710.
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Sylwia Borska, Malgorzata Drag-Zalesinska, Teresa Wysocka, Miroslaw Sopel, Malgorzata Dumanska, Maciej Zabel & Piotr Dziegiel. (2010) Antiproliferative and pro-apoptotic effects of quercetin on human pancreatic carcinoma cell lines EPP85-181P and EPP85-181RDB.. Folia Histochemica et Cytobiologica 48:2.
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Claudius Coburger, Jörg Wollmann, Martin Krug, Christiane Baumert, Marianne Seifert, Joséf Molnár, Hermann Lage & Andreas Hilgeroth. (2010) Novel structure–activity relationships and selectivity profiling of cage dimeric 1,4-dihydropyridines as multidrug resistance (MDR) modulators. Bioorganic & Medicinal Chemistry 18:14, pages 4983-4990.
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Sylwia Borska, Miroslaw Sopel, Magdalena Chmielewska, Maciej Zabel & Piotr Dziegiel. (2010) Quercetin as a Potential Modulator of P-Glycoprotein Expression and Function in Cells of Human Pancreatic Carcinoma Line Resistant to Daunorubicin. Molecules 15:2, pages 857-870.
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O. V. Melnikov, O. Yu. Gorbenko, M. N. M̌arkelova, A. R. Kaul, V. A. Atsarkin, V. V. Demidov, C. Soto, E. J. Roy & B. M. Odintsov. (2008) Ag‐doped manganite nanoparticles: New materials for temperature‐controlled medical hyperthermia. Journal of Biomedical Materials Research Part A 91A:4, pages 1048-1055.
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Claudius Coburger, Hermann Lage, Josef Molnár & Andreas Hilgeroth. (2008) Impact of Novel MDR Modulators on Human Cancer Cells: Reversal Activities and Induction Studies. Pharmaceutical Research 26:1, pages 182-188.
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Claudius Coburger, Jörg Wollmann, Christiane Baumert, Martin Krug, Josef Molnár, Hermann Lage & Andreas Hilgeroth. (2008) Novel Insight in Structure−Activity Relationship and Bioanalysis of P-Glycoprotein Targeting Highly Potent Tetrakishydroxymethyl Substituted 3,9-Diazatetraasteranes. Journal of Medicinal Chemistry 51:18, pages 5871-5874.
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Reinhold Schäfer, Oleg I. Tchernitsa, Balazs Györffy, Violeta Serra, Rula Abdul-Ghani, Per Lund & Christine Sers. (2007) Functional transcriptomics: An experimental basis for understanding the systems biology for cancer cells. Advances in Enzyme Regulation 47:1, pages 41-62.
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Balázs Györffy. 2007. Targeted Therapies in Cancer. Targeted Therapies in Cancer 37 50 .
Balázs Györffy, Violeta Serra, Karsten Jürchott, Rula Abdul-Ghani, Mitch Garber, Ulrike Stein, Iver Petersen, Hermann Lage, Manfred Dietel & Reinhold Schäfer. (2005) Prediction of doxorubicin sensitivity in breast tumors based on gene expression profiles of drug-resistant cell lines correlates with patient survival. Oncogene 24:51, pages 7542-7551.
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Petra Kowalski, Pawel Surowiak & Hermann Lage. (2005) Reversal of different drug-resistant phenotypes by an autocatalytic multitarget multiribozyme directed against the transcripts of the ABC transporters MDR1/P-gp, MRP2, and BCRP. Molecular Therapy 11:4, pages 508-522.
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Hermann Lage. (2004) Proteomics in cancer cell research: an analysis of therapy resistance. Pathology - Research and Practice 200:2, pages 105-117.
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Holger Tönnies & Hermann Lage. (2004) Chromosomal imbalances associated with drug resistance and thermoresistance in human pancreatic carcinoma cells. European Journal of Cell Biology 83:10, pages 591-601.
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Julia Poland, Andrea Urbani, Hermann Lage, Martina Schnölzer & Pranav Sinha. (2004) Study of the development of thermoresistance in human pancreatic carcinoma cell lines using proteome analysis. ELECTROPHORESIS 25:1, pages 173-183.
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Holger Woehlecke, Hiroyuki Osada, Andreas Herrmann & Hermann Lage. (2003) Reversal of breast cancer resistance protein–mediated drug resistance by tryprostatin A. International Journal of Cancer 107:5, pages 721-728.
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Christiane Nieth, Axel Priebsch, Alexandra Stege & Hermann Lage. (2003) Modulation of the classical multidrug resistance (MDR) phenotype by RNA interference (RNAi). FEBS Letters 545:2-3, pages 144-150.
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Holger Tönnies, Julia Poland, Pranav Sinha & Hermann Lage. (2002) Association of genomic imbalances with drug resistance and thermoresistance in human gastric carcinoma cells. International Journal of Cancer 103:6, pages 752-758.
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Hermann Lage. (2003) Molecular Analysis of Therapy Resistance in Gastric Cancer. Digestive Diseases 21:4, pages 326-338.
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Ulrike Stein, Hermann Lage, Andreas Jordan, Wolfgang Walther, Susan E. Bates, Thomas Litman, Peter Hohenberger & Manfred Dietel. (2001) Impact of BCRP/MXR, MRP1 and MDR1/P‐Glycoprotein on thermoresistant variants of atypical and classical multidrug resistant cancer cells. International Journal of Cancer 97:6, pages 751-760.
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Julia Poland, Dirk Schadendorf, Hermann Lage, Martina Schnölzer, Julio E. Celis & Pranav Sinha. (2002) Study of Therapy Resistance in Cancer Cells with Functional Proteome Analysis. Clinical Chemistry and Laboratory Medicine 40:3.
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Xin Wang. (2002) Differential display of vincristine-resistance-related genes in gastric cancer SGC7901 cell. World Journal of Gastroenterology 8:1, pages 54.
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Hermann Lage, Christin Perlitz, Rupert Abele, Robert Tampé, Manfred Dietel, Dirk Schadendorf & Pranav Sinha. (2001) Enhanced expression of human ABC‐transporter tap is associated with cellular resistance to mitoxantrone. FEBS Letters 503:2-3, pages 179-184.
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Pranav Sinha, Julia Poland, Martina Schnölzer, Julio E. Celis & Hermann Lage. (2001) Characterization of the differential protein expression associated with thermoresistance in human gastric carcinoma cell lines. ELECTROPHORESIS 22:14, pages 2990-3000.
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Hermann Lage & Manfred Dietel. (2000) Effect of the breast-cancer resistance protein on atypical multidrug resistance. The Lancet Oncology 1:3, pages 169-175.
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