Advanced search
Publication Cover
Liquid Crystals Volume 38, 2011 - Issue 11-12: Liquid Crystals that affected the World
Submit an article Journal homepage
629
Views
39
CrossRef citations to date
0
Altmetric
Invited Topical Review

Cationic liposome–nucleic acid complexes: liquid crystal phases with applications in gene therapy

C.R. Safinya Materials Department, Physics Department, and Molecular, Cellular, and Developmental Biology Department, University of California, Santa Barbara, CA, USACorrespondence[email protected]
,
K.K. Ewert Materials Department, Physics Department, and Molecular, Cellular, and Developmental Biology Department, University of California, Santa Barbara, CA, USA
&
C. Leal Materials Department, Physics Department, and Molecular, Cellular, and Developmental Biology Department, University of California, Santa Barbara, CA, USA
Pages 1715-1723 | Received 08 Sep 2011, Accepted 12 Sep 2011, Published online: 22 Nov 2011

Citations (39)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (6)

Marilyn Porras-Gomez & Cecilia Leal. (2019) Lipid-based liquid crystalline films and solutions for the delivery of cargo to cells. Liquid Crystals Reviews 7:2, pages 167-182.
Read now
J. Shankaraswamy, Shikhar Tyagi, Anju Singh, Daisuke Miyoshi & Sarika Saxena. (2019) Metal sensitive and DNA concentration dependent structural rearrangement of short oligonucleotide into large suprastructures. Journal of Biomolecular Structure and Dynamics 37:9, pages 2211-2218.
Read now
Izabela Korbecka, Damian Pociecha & Zbigniew Galewski. (2017) 4-Octylphenylazo-4′-phenyl alkanoates – homologous series of azomesogens with extremely rich liquid-crystalline polymorphism. Liquid Crystals 44:10, pages 1600-1606.
Read now
Xiao-Feng Liu, Xiao-Xu Xu, Qun Li, Jian-She Hu, Li-Qun Yang, Qi-Fan Chen & Yan-Hua Lu. (2017) New side chain cholesterol-functionalised aliphatic polycarbonate copolymer: synthesis and phase behaviour. Liquid Crystals 44:9, pages 1356-1364.
Read now
Ivo Lopes, Ana C. N. Oliveira, Marisa P. Sárria, João P. Neves Silva, Odete Gonçalves, Andreia C. Gomes & Maria Elisabete C. D. Real Oliveira. (2016) Monoolein-based nanocarriers for enhanced folate receptor-mediated RNA delivery to cancer cells. Journal of Liposome Research 26:3, pages 199-210.
Read now
Alberto Ciferri. (2012) A supramolecular polymerisation model for the structurisation of DNA–lipid complexes. Liquid Crystals 39:10, pages 1231-1236.
Read now

Articles from other publishers (33)

Santosh Prasad Gupta, Mukesh Chandra Bos, Shallu Dhingra & Santanu Kumar Pal. (2023) A theoretical investigation on the relative stability of the columnar hexagonal and columnar square phases of discotic molecules. Journal of Molecular Liquids 386, pages 122497.
Crossref
Jacob Rueben, Ashish Jayaraman, Mahesh K. Mahanthappa & Cecilia Leal. (2022) Near-Infrared-Triggered Reversible Transformations of Gold Nanorod-Laden Lipid Assemblies: Implications for Cellular Delivery. ACS Applied Nano Materials 5:1, pages 710-717.
Crossref
Federica Ponti, Matilde Campolungo, Clara Melchiori, Nina Bono & Gabriele Candiani. (2021) Cationic lipids for gene delivery: many players, one goal. Chemistry and Physics of Lipids 235, pages 105032.
Crossref
Zheng‐Rong Lu, Victoria E. A. Laney, Ryan Hall & Nadia Ayat. (2020) Environment‐Responsive Lipid/siRNA Nanoparticles for Cancer Therapy. Advanced Healthcare Materials 10:5, pages 2001294.
Crossref
Sampa Sarkar, Nhiem Tran, Sarvesh Kumar Soni, Charlotte E. Conn & Calum J. Drummond. (2020) Size-Dependent Encapsulation and Release of dsDNA from Cationic Lyotropic Liquid Crystalline Cubic Phases. ACS Biomaterials Science & Engineering 6:8, pages 4401-4413.
Crossref
Jenny Marie Andersson, Quoc Dat Pham, Helena Mateos, Sylvia Eriksson, Pia Harryson & Emma Sparr. (2020) The plant dehydrin Lti30 stabilizes lipid lamellar structures in varying hydration conditions. Journal of Lipid Research 61:7, pages 1014-1024.
Crossref
Sakinah Mohd Alauddin, Nurul Fadhilah Kamalul Aripin, Thamil Selvi Velayutham & Alfonso Martinez-Felipe. (2020) Liquid Crystalline Copolymers Containing Sulfonic and Light-Responsive Groups: From Molecular Design to Conductivity. Molecules 25:11, pages 2579.
Crossref
Elham Bidram, Yasaman Esmaeili, Hadi Ranji-Burachaloo, Nuha Al-Zaubai, Ali Zarrabi, Alastair Stewart & Dave E. Dunstan. (2019) A concise review on cancer treatment methods and delivery systems. Journal of Drug Delivery Science and Technology 54, pages 101350.
Crossref
Lei Zhang, Chao Ma, Jing Sun, Baiqi Shao, Giuseppe Portale, Dong Chen, Kai Liu & Andreas Herrmann. (2018) Genetically Engineered Supercharged Polypeptide Fluids: Fast and Persistent Self-Ordering Induced by Touch. Angewandte Chemie International Edition 57:23, pages 6878-6882.
Crossref
Lei Zhang, Chao Ma, Jing Sun, Baiqi Shao, Giuseppe Portale, Dong Chen, Kai Liu & Andreas Herrmann. (2018) Genetically Engineered Supercharged Polypeptide Fluids: Fast and Persistent Self-Ordering Induced by Touch. Angewandte Chemie 130:23, pages 6994-6998.
Crossref
Antje Ziller, Sara S. Nogueira, Eva Hühn, Sergio S. Funari, Gerald Brezesinski, Hermann Hartmann, Ugur Sahin, Heinrich Haas & Peter Langguth. (2018) Incorporation of mRNA in Lamellar Lipid Matrices for Parenteral Administration. Molecular Pharmaceutics 15:2, pages 642-651.
Crossref
Nily Dan. 2018. Lipid Nanocarriers for Drug Targeting. Lipid Nanocarriers for Drug Targeting 529 562 .
Kai Liu, Lifei Zheng, Chao Ma, Robert Göstl & Andreas Herrmann. (2017) DNA–surfactant complexes: self-assembly properties and applications. Chemical Society Reviews 46:16, pages 5147-5172.
Crossref
Marc A Ilies, Uttam Satyal & Vishnu D. Sharma. 2017. Control of Amphiphile Self-Assembling at the Molecular Level: Supra-Molecular Assemblies with Tuned Physicochemical Properties for Delivery Applications. Control of Amphiphile Self-Assembling at the Molecular Level: Supra-Molecular Assemblies with Tuned Physicochemical Properties for Delivery Applications 1 34 .
Nily Dan. 2017. Nanostructures for Novel Therapy. Nanostructures for Novel Therapy 517 538 .
Manuel M. Neidhardt, Manpreet Wolfrum, Stuart Beardsworth, Tobias Wöhrle, Wolfgang Frey, Angelika Baro, Cosima Stubenrauch, Frank Giesselmann & Sabine Laschat. (2016) Tyrosine-Based Ionic Liquid Crystals: Switching from a Smectic A to a Columnar Mesophase by Exchange of the Spherical Counterion. Chemistry - A European Journal 22:46, pages 16494-16504.
Crossref
Kai K. Ewert, Venkata Ramana Kotamraju, Ramsey N. Majzoub, Victoria M. Steffes, Emily A. Wonder, Tambet Teesalu, Erkki Ruoslahti & Cyrus R. Safinya. (2016) Synthesis of linear and cyclic peptide–PEG–lipids for stabilization and targeting of cationic liposome–DNA complexes. Bioorganic & Medicinal Chemistry Letters 26:6, pages 1618-1623.
Crossref
Alberto Ciferri. (2015) Translation of Molecular Order to the Macroscopic Level. Chemical Reviews 116:3, pages 1353-1374.
Crossref
L. Pigeon, C. Gonçalves, C. Pichon & P. Midoux. (2016) Evidence for plasmid DNA exchange after polyplex mixing. Soft Matter 12:33, pages 7012-7019.
Crossref
Nawal Belmadi, Patrick Midoux, Pascal Loyer, Catherine Passirani, Chantal Pichon, Tony Le Gall, Paul-Alain Jaffres, Pierre Lehn & Tristan Montier. (2015) Synthetic vectors for gene delivery: An overview of their evolution depending on routes of administration.. Biotechnology Journal 10:9, pages 1370-1389.
Crossref
Nily Dan. (2015) Lipid-Nucleic Acid Supramolecular Complexes: Lipoplex Structure and the Kinetics of Formation. AIMS Biophysics 2:2, pages 163-183.
Crossref
Ariane Tschiche, Shashwat Malhotra & Rainer Haag. (2014) Nonviral gene delivery with dendritic self-assembling architectures. Nanomedicine 9:5, pages 667-693.
Crossref
Nily Dan & Dganit Danino. (2014) Structure and kinetics of lipid–nucleic acid complexes. Advances in Colloid and Interface Science 205, pages 230-239.
Crossref
Chia-Ling Chan, Kai K. Ewert, Ramsey N. Majzoub, Yeu-Kuang Hwu, Keng S. Liang, Cecília Leal & Cyrus R. Safinya. (2014) Optimizing cationic and neutral lipids for efficient gene delivery at high serum content. The Journal of Gene Medicine 16:3-4, pages 84-96.
Crossref
Cyrus R. Safinya, Kai K. Ewert, Ramsey N. Majzoub & Cecília Leal. (2014) Cationic liposome–nucleic acid complexes for gene delivery and gene silencing. New J. Chem. 38:11, pages 5164-5172.
Crossref
Cristine Gonçalves, Mathieu Berchel, Marie-Pierre Gosselin, Virginie Malard, Hervé Cheradame, Paul-Alain Jaffrès, Philippe Guégan, Chantal Pichon & Patrick Midoux. (2014) Lipopolyplexes comprising imidazole/imidazolium lipophosphoramidate, histidinylated polyethyleneimine and siRNA as efficient formulation for siRNA transfection. International Journal of Pharmaceutics 460:1-2, pages 264-272.
Crossref
M Kornreich, R Avinery & R Beck. (2013) Modern X-ray scattering studies of complex biological systems. Current Opinion in Biotechnology 24:4, pages 716-723.
Crossref
Kazuki Iwabata, Urara Sugai, Yasutaka Seki, Hirokazu Furue & Kengo Sakaguchi. (2013) Applications of Biomaterials to Liquid Crystals. Molecules 18:4, pages 4703-4717.
Crossref
Francesca Cuomo, Monica Mosca, Sergio Murgia, Andrea Ceglie & Francesco Lopez. (2013) Oligonucleotides and polynucleotides condensation onto liposome surface: Effects of the base and of the nucleotide length. Colloids and Surfaces B: Biointerfaces 104, pages 239-244.
Crossref
Zia ur Rehman, Inge S. Zuhorn & Dick Hoekstra. (2013) How cationic lipids transfer nucleic acids into cells and across cellular membranes: Recent advances. Journal of Controlled Release 166:1, pages 46-56.
Crossref
Daniel Harries, Sylvio May & Avinoam Ben-Shaul. (2013) Counterion release in membrane–biopolymer interactions. Soft Matter 9:39, pages 9268.
Crossref
Cecília Leal, Kai K. Ewert, Nathan F. Bouxsein, Rahau S. Shirazi, Youli Li & Cyrus R. Safinya. (2013) Stacking of short DNA induces the gyroid cubic-to-inverted hexagonal phase transition in lipid–DNA complexes. Soft Matter 9:3, pages 795-804.
Crossref
Cyrus R. Safinya & Kai K. Ewert. (2012) Liposomes derived from molecular vases. Nature 489:7416, pages 372-374.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.