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Brain Injury Volume 19, 2005 - Issue 7
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Original Article

Effects of the dopaminergic agent and NMDA receptor antagonist amantadine on cognitive function, cerebral glucose metabolism and D2 receptor availability in chronic traumatic brain injury: A study using positron emission tomography (PET)

M. F. Kraus Center for Cognitive Medicine, Department of Psychiatry, University of Illinois at Chicago, Chicago, IL, USACorrespondence[email protected]
,
G. S. Smith The Zucker Hillside Hospital and Center for Neurosciences, North Shore-Long Island Jewish Research Institute, North Shore-Long Island Jewish Health System, New York
,
M. Butters Departments of Psychiatry, University of Pittsburgh Medical Center, Pittsburgh, USA
,
A. J. Donnell Center for Cognitive Medicine, Department of Psychiatry, University of Illinois at Chicago, Chicago, IL, USA
,
E. Dixon Neurosurgery, University of Pittsburgh Medical Center, Pittsburgh, USA
,
C. Yilong The Zucker Hillside Hospital and Center for Neurosciences, North Shore-Long Island Jewish Research Institute, North Shore-Long Island Jewish Health System, New York
&
D. Marion Department of Neurological Surgery, Boston University Medical Center, Boston, MA, USA
 show all
Pages 471-479 | Received 25 May 2004, Accepted 20 Sep 2004, Published online: 03 Jul 2009

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Thomas Müller, Peter Riederer & Wilfried Kuhn. (2023) Aminoadamantanes: from treatment of Parkinson’s and Alzheimer’s disease to symptom amelioration of long COVID-19 syndrome?. Expert Review of Clinical Pharmacology 16:2, pages 101-107.
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Moein Khormali, Sama Heidari, Sana Ahmadi, Melika Arab Bafrani, Vali Baigi & Mahdi Sharif-Alhoseini. (2022) N-methyl-D-aspartate receptor antagonists in improving cognitive deficits following traumatic brain injury: a systematic review. Brain Injury 36:9, pages 1071-1088.
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Peggy Spauwen, Bert Ter Mors, Peter van Harten, Anne-Fleur Domensino, Rudolf Ponds & Caroline van Heugten. (2022) Efficacy and safety of amantadine as a treatment for apathy after brain injury: Two single-case experimental design studies. Neuropsychological Rehabilitation 32:6, pages 872-896.
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Heather M. Ma & Ross D. Zafonte. (2020) Amantadine and memantine: a comprehensive review for acquired brain injury. Brain Injury 34:3, pages 299-315.
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B.J. Ter Mors, A.P.M. Backx, P. Spauwen, R.W.H.M. Ponds, P.N. Van Harten & C.M. Van Heugten. (2019) Efficacy of amantadine on behavioural problems due to acquired brain injury: A systematic review. Brain Injury 33:9, pages 1137-1150.
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Thomas Müller, Wilfried Kuhn & Jan-Dominique Möhr. (2019) Evaluating ADS5102 (amantadine) for the treatment of Parkinson’s disease patients with dyskinesia. Expert Opinion on Pharmacotherapy 20:10, pages 1181-1187.
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Swati Mehta, Amanda McIntyre, Shannon Janzen, Jerome Iruthayarajah, Ali Bateman & Robert Teasell. (2018) Pharmacological management of agitation among individuals with moderate to severe acquired brain injury: A systematic review. Brain Injury 32:3, pages 287-296.
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Ryo Shimada, Keiichi Abe, Rui Furutani & Kazuhiko Kibayashi. (2014) Changes in dopamine transporter expression in the midbrain following traumatic brain injury: an immunohistochemical and in situ hybridization study in a mouse model. Neurological Research 36:3, pages 239-246.
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Samir Al-Adawi, Heather Hoaglin, Fariba Vesali, Atsu S. S. Dorvlo & David T. Burke. (2009) Effect of amantadine on the sleep–wake cycle of an inpatient with brain injury. Brain Injury 23:6, pages 559-565.
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Olga N. Kokiko & Robert J. Hamm. (2007) A review of pharmacological treatments used in experimental models of traumatic brain injury. Brain Injury 21:3, pages 259-274.
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