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Original

Effects of medroxyprogesterone acetate on cerebral oedema and spatial learning performance after traumatic brain injury in rats

, , & , PhD
Pages 107-113 | Received 05 Nov 2007, Accepted 14 Dec 2007, Published online: 03 Jul 2009

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Janet P. Niemeier, Jennifer H. Marwitz, William C. Walker, Lynne C. Davis, Tamara Bushnik, David L. Ripley & Jessica M. Ketchum. (2013) Are there cognitive and neurobehavioural correlates of hormonal neuroprotection for women after TBI?. Neuropsychological Rehabilitation 23:3, pages 363-382.
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Bar Richmond-Hacham, Haim Izchak, Tomer Elbaum, Doaa Qubty, Miaad Bader, Vardit Rubovitch & Chaim G. Pick. (2022) Sex-specific cognitive effects of mild traumatic brain injury to the frontal and temporal lobes. Experimental Neurology 352, pages 114022.
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Xin Huang, Wendong You, Yuanrun Zhu, Kangli Xu, Xiaofeng Yang & Liang Wen. (2021) Microglia: A Potential Drug Target for Traumatic Axonal Injury. Neural Plasticity 2021, pages 1-13.
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Iqbal Sayeed, Bushra Wali, David B. Guthrie, Manohar T. Saindane, Michael G. Natchus, Dennis C. Liotta & Donald G. Stein. (2019) Development of a novel progesterone analog in the treatment of traumatic brain injury. Neuropharmacology 145, pages 292-298.
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Craig S. Atwood & Samuel F. Ekstein. (2019) Human versus non-human sex steroid use in hormone replacement therapies part 1: Preclinical data. Molecular and Cellular Endocrinology 480, pages 12-35.
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Stefanie Howell & Grace S. Griesbach. (2018) The interplay between neuroendocrine and sleep alterations following traumatic brain injury. NeuroRehabilitation 43:3, pages 327-345.
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Yunhui Zeng, Yujie Zhang, Junpeng Ma & Jianguo Xu. (2015) Progesterone for Acute Traumatic Brain Injury: A Systematic Review of Randomized Controlled Trials. PLOS ONE 10:10, pages e0140624.
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Frank Z. Stanczyk & Bhagu R. Bhavnani. (2015) Reprint of “Use of medroxyprogesterone acetate for hormone therapy in postmenopausal women: Is it safe?”. The Journal of Steroid Biochemistry and Molecular Biology 153, pages 151-159.
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Courtney L. Robertson, Emin Fidan, Rachel M. Stanley, Corina Noje & Hülya Bayir. (2015) Progesterone for Neuroprotection in Pediatric Traumatic Brain Injury. Pediatric Critical Care Medicine 16:3, pages 236-244.
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Frank Z. Stanczyk & Bhagu R. Bhavnani. (2014) Use of medroxyprogesterone acetate for hormone therapy in postmenopausal women: Is it safe?. The Journal of Steroid Biochemistry and Molecular Biology 142, pages 30-38.
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Gabriel Alcalá-Cerra. (2013) Different pharmacological effects of progestins should be considered when applied in traumatic brain injury patients. Clinical Neurology and Neurosurgery 115:12, pages 2554-2555.
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Eric R. Deutsch, Tamara R. Espinoza, Fahim Atif, Elise Woodall, Jordan Kaylor & David W. Wright. (2013) Progesterone's role in neuroprotection, a review of the evidence. Brain Research 1530, pages 82-105.
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Lana J. Mawhinney, Davita Mabourakh & Michael C. Lewis. (2012) Gender-Specific Differences in the Central Nervous System’s Response to Anesthesia. Translational Stroke Research 4:4, pages 462-475.
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Frank Z. StanczykJanet P. Hapgood, Sharon Winer & Daniel R. MishellJr.Jr.. (2013) Progestogens Used in Postmenopausal Hormone Therapy: Differences in Their Pharmacological Properties, Intracellular Actions, and Clinical Effects. Endocrine Reviews 34:2, pages 171-208.
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Alicia A. Walf, Jason J. Paris, Madeline E. Rhodes, James W. Simpkins & Cheryl A. Frye. (2011) Divergent mechanisms for trophic actions of estrogens in the brain and peripheral tissues. Brain Research 1379, pages 119-136.
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Fang Hua, Jun Wang, Tauheed Ishrat, Wenjing Wei, Fahim Atif, Iqbal Sayeed & Donald G Stein. (2011) Genomic profile of Toll-like receptor pathways in traumatically brain-injured mice: effect of exogenous progesterone. Journal of Neuroinflammation 8:1, pages 42.
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Cheryl A. Frye, Alicia A. Walf & Jason J. Paris. (2010) Conjugated equine estrogen, with medroxyprogesterone acetate, enhances formation of 5α-reduced progestogens and reduces anxiety-like behavior of middle-aged rats. Behavioural Pharmacology 21:5-6, pages 530-539.
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Nioka C. Lowry, Laura P. Pardon, Melissa A. Yates & Janice M. Juraska. (2010) Effects of long-term treatment with 17 β-estradiol and medroxyprogesterone acetate on water maze performance in middle aged female rats. Hormones and Behavior 58:2, pages 200-207.
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Cheryl A. Frye, Carolyn J. Koonce & Alicia A. Walf. (2010) Mnemonic effects of progesterone to mice require formation of 3α,5α-THP. NeuroReport 21:8, pages 590-595.
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Sivan Vadakkadath Meethal, Tianbing Liu, Hsien W. Chan, Erika Ginsburg, Andrea C. Wilson, Danielle N. Gray, Richard L. Bowen, Barbara K. Vonderhaar & Craig S. Atwood. (2009) Identification of a regulatory loop for the synthesis of neurosteroids: a steroidogenic acute regulatory protein-dependent mechanism involving hypothalamic-pituitary-gonadal axis receptors. Journal of Neurochemistry 110:3, pages 1014-1027.
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Markus Kipp & Cordian Beyer. (2009) Impact of sex steroids on neuroinflammatory processes and experimental multiple sclerosis. Frontiers in Neuroendocrinology 30:2, pages 188-200.
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Alejandro F. De Nicola, Florencia Labombarda, Maria Claudia Gonzalez Deniselle, Susana L. Gonzalez, Laura Garay, Maria Meyer, Gisella Gargiulo, Rachida Guennoun & Michael Schumacher. (2009) Progesterone neuroprotection in traumatic CNS injury and motoneuron degeneration. Frontiers in Neuroendocrinology 30:2, pages 173-187.
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