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Original Articles

ICU sedation with dexmedetomidine after severe traumatic brain injury

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Pages 1266-1270 | Received 01 Feb 2016, Accepted 04 May 2016, Published online: 26 Jul 2016

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (2)

Ahmet Sen, Basar Erdivanlı, Levent Tümkaya, Hüseyin Avni Uydu, Tolga Mercantepe, Şule Batcik & Abdullah Ozdemir. (2024) The effects of dexmedetomidine on trauma-induced secondary injury in rat brain. Neurological Research 46:1, pages 23-32.
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Brendan P. George, J. Priyanka Vakkalanka, Karisa K. Harland, Brett Faine, Stacey Rewitzer, Anne Zepeski, Brian M. Fuller, Nicholas M. Mohr & Azeemuddin Ahmed. (2020) Sedation Depth is Associated with Increased Hospital Length of Stay in Mechanically Ventilated Air Medical Transport Patients: A Cohort Study. Prehospital Emergency Care 24:6, pages 783-792.
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Articles from other publishers (37)

Zhu Deng, Yong Gu, Le Luo, Lin Deng, Yingwei Li & Wanyong Huang. (2024) The effect of dexmedetomidine on the postoperative recovery of patients with severe traumatic brain injury undergoing craniotomy treatment: a retrospective study. European Journal of Medical Research 29:1.
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Sunny Yang LiuMargot Kelly-HedrickNancy TemkinJason BarberJordan KomisarowJordan HatfieldTetsu OhnumaGeoffrey ManleyMiriam M. TreggiariKatharine ColtonMonica S. VavilalaRamesh GrandhiDaniel T. LaskowitzJoseph P. MathewAdrian HernandezMichael L. JamesKarthik RaghunathanBen GoldsteinAmy MarkowitzVijay Krishnamoorthy. (2023) Association of Early Dexmedetomidine Utilization With Clinical and Functional Outcomes Following Moderate-Severe Traumatic Brain Injury: A Transforming Clinical Research and Knowledge in Traumatic Brain Injury Study*. Critical Care Medicine 52:4, pages 607-617.
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Jordan Hatfield, Alexandria L. Soto, Margot Kelly-Hedrick, Samantha Kaplan, Jordan M. Komisarow, Tetsu Ohnuma & Vijay Krishnamoorthy. (2024) Safety, Efficacy, and Clinical Outcomes of Dexmedetomidine for Sedation in Traumatic Brain Injury: A Scoping Review. Journal of Neurosurgical Anesthesiology 36:2, pages 101-108.
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Mar Saavedra-Mitjans, Anne Julie Frenette, Victoria A. McCredie, Lisa Burry, Caroline Arbour, Sangeeta Mehta, Emmanuel Charbonney, Han Ting Wang, Martin Albert, Francis Bernard & David Williamson. (2023) Physicians’ beliefs and perceived importance of traumatic brain injury-associated agitation in critically ill patients: a survey of Canadian intensivistsCroyances et importance perçue par les médecins de l’agitation associée aux traumatismes crâniens chez la patientèle gravement malade : un sondage réalisé auprès d’intensivistes au Canada. Canadian Journal of Anesthesia/Journal canadien d'anesthésie 71:2, pages 264-273.
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Jean-François Payen, Clotilde Schilte & Alexandre Behouche. 2024. Traumatic Brain Injury. Traumatic Brain Injury 243 254 .
Rianne G.F. Dolmans, Brian V. Nahed, Faith C. Robertson, Wilco C. Peul, Eric S. Rosenthal & Marike L.D. Broekman. (2023) Practice-Pattern Variation in Sedation of Neurotrauma Patients in the Intensive Care Unit: An International Survey. Journal of Intensive Care Medicine 38:12, pages 1143-1150.
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Hosseinali Khalili, Amin Niakan, Ali Rajabpour-Sanati, Elaheh Shaghaghian, Mohammad Hesam Alavi, Maryam Dehghankhalili & Fariborz Ghaffarpasand. (2023) Effect of Dexmedotomdine hydrochloride (Percedex®) on functional outcome of patients with moderate and severe traumatic brain injury. Journal of Clinical Neuroscience 114, pages 146-150.
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Jean-François Payen, Clotilde Schilte, Barthelemy Bertrand & Alexandre Behouche. (2023) Toward individualized sedation in patients with acute brain damage. Anaesthesia Critical Care & Pain Medicine 42:4, pages 101219.
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Toby JeffcoteTimothy Weir, James Anstey, Robert Mcnamara, Rinaldo BellomoAndrew Udy. (2023) The Impact of Sedative Choice on Intracranial and Systemic Physiology in Moderate to Severe Traumatic Brain Injury: A Scoping Review. Journal of Neurosurgical Anesthesiology 35:3, pages 265-273.
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Ebtesam Abdulla, Amit Agrawal, Rafael Cincu, Tariq Janjua & Luis Rafael Moscote-Salazar. (2023) Cooperative Sedation in Moderate Traumatic Brain Injury: A Tool for Neurocritical Care Management. Journal of Neurointensive Care 6:1, pages 67-68.
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Jinbu Xu & Qing Xiao. (2022) Assessment of the effects of dexmedetomidine on outcomes of traumatic brain injury using propensity score analysis. BMC Anesthesiology 22:1.
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Alexandre Behouche, Clotilde Schilte & Jean-François Payen. (2022) Hypertension intracrânienne et gestion de la sédation. Anesthésie & Réanimation 8:4, pages 396-401.
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Yanxia Huang, Yunxin Deng, Renjing Zhang, Mei Meng & Dechang Chen. (2022) Comparing the Effect of Dexmedetomidine and Midazolam in Patients with Brain Injury. Brain Sciences 12:6, pages 752.
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Dicle Karakaya, Canan Cakir-Aktas, Sennur Uzun, Figen Soylemezoglu & Melike Mut. (2021) Tailored Therapeutic Doses of Dexmedetomidine in Evolving Neuroinflammation after Traumatic Brain Injury. Neurocritical Care 36:3, pages 802-814.
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Slavica Kvolik, Nenad Koruga & Sonja Skiljic. (2022) Analgesia in the Neurosurgical Intensive Care Unit. Frontiers in Neurology 12.
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R. K. Kayambankadzanja, R. Samwel & T. Baker. (2022) Pragmatic sedation strategies to prevent secondary brain injury in low‐resource settings. Anaesthesia 77:S1, pages 43-48.
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C. Bureau & A. Demoule. (2022) Weaning from mechanical ventilation in neurocritical care. Revue Neurologique 178:1-2, pages 111-120.
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Denise Battaglini, Chiara Robba & Paolo Pelosi. 2022. Perioperative Neuroscience. Perioperative Neuroscience 139 154 .
Hugues Marechal, Aline Defresne, Javier Montupil & Vincent Bonhomme. 2022. Essentials of Evidence-Based Practice of Neuroanesthesia and Neurocritical Care. Essentials of Evidence-Based Practice of Neuroanesthesia and Neurocritical Care 321 358 .
Indu Kapoor, Charu Mahajan & Hemanshu Prabhakar. (2021) Dexmedetomidine in Modern Neuroanesthesia Practice. Current Anesthesiology Reports 11:3, pages 181-188.
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Véronique Bilodeau, Mar Saavedra‐Mitjans, Anne Julie Frenette, Lisa Burry, Martin Albert, Francis Bernard & David R. Williamson. (2021) Safety of dexmedetomidine for the control of agitation in critically ill traumatic brain injury patients: a descriptive study. Journal of Clinical Pharmacy and Therapeutics 46:4, pages 1020-1026.
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Shane Musick & Anthony Alberico. (2021) Neurologic Assessment of the Neurocritical Care Patient. Frontiers in Neurology 12.
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Swagata Tripathy. (2021) Consensus Statement on Analgo-sedation in Neurocritical Care and Review of Literature. Indian Journal of Critical Care Medicine 25:2, pages 126-133.
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Sarah Aubanel, Florian Bruiset, Claire Chapuis, Gerald Chanques & Jean-François Payen. (2020) Therapeutic options for agitation in the intensive care unit. Anaesthesia Critical Care & Pain Medicine 39:5, pages 639-646.
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Rui-Zhe Zheng, Zhong-Qi Lei, Run-Ze Yang, Guo-Hui Huang & Guang-Ming Zhang. (2020) Identification and Management of Paroxysmal Sympathetic Hyperactivity After Traumatic Brain Injury. Frontiers in Neurology 11.
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Hasan B. Alam, Gary Vercruysse, Matthew Martin, Carlos V.R. Brown, Karen Brasel, Ernest E. Moore, Jack Sava, David Ciesla & Kenji Inaba. (2020) Western Trauma Association critical decisions in trauma: Management of intracranial hypertension in patients with severe traumatic brain injuries. Journal of Trauma and Acute Care Surgery 88:2, pages 345-351.
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Geir Olav Dahle. 2020. Management of Severe Traumatic Brain Injury. Management of Severe Traumatic Brain Injury 461 465 .
Niklas Marklund. 2020. Management of Severe Traumatic Brain Injury. Management of Severe Traumatic Brain Injury 259 265 .
Simone Carelli, Gennaro De Pascale, Nicoletta Filetici, Maria Grazia Bocci, Gian Marco Maresca, Salvatore Lucio Cutuli, Cecilia Maria Pizzo, Giuseppe Bello, Luca Montini, Anselmo Caricato, Giorgio Conti & Massimo Antonelli. (2019) The place of dexmedetomidine light sedation in patients with acute brain injury. Critical Care 23:1.
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Nan Lin, Laszlo Vutskits, John F. Bebawy & Adrian W. Gelb. (2019) Perspectives on Dexmedetomidine Use for Neurosurgical Patients. Journal of Neurosurgical Anesthesiology 31:4, pages 366-377.
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Henry W. Caplan & Charles S. CoxJr.Jr.. (2019) Resuscitation Strategies for Traumatic Brain Injury. Current Surgery Reports 7:7.
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Katleen Chester, Kristy N. Greene & Gretchen M. Brophy. 2019. Textbook of Neuroanesthesia and Neurocritical Care. Textbook of Neuroanesthesia and Neurocritical Care 299 318 .
Deacon Farrell & Audrée A. Bendo. (2018) Perioperative Management of Severe Traumatic Brain Injury: What Is New?. Current Anesthesiology Reports 8:3, pages 279-289.
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Shalendra Singh, Rajendra Singh Chouhan, Ashish Bindra & Nayani Radhakrishna. (2018) Comparison of effect of dexmedetomidine and lidocaine on intracranial and systemic hemodynamic response to chest physiotherapy and tracheal suctioning in patients with severe traumatic brain injury. Journal of Anesthesia 32:4, pages 518-523.
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Joanna L. Stollings, Jennifer L. Thompson, Benjamin A. Ferrell, Mika Scheinin, Grant R. Wilkinson, Christopher G. Hughes, Ayumi K. Shintani, E. Wesley Ely, Timothy D. Girard, Pratik P. Pandharipande & Mayur B. Patel. (2018) Sedative Plasma Concentrations and Delirium Risk in Critical Illness. Annals of Pharmacotherapy 52:6, pages 513-521.
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Niklas Marklund. (2017) The Neurological Wake-up Test—A Role in Neurocritical Care Monitoring of Traumatic Brain Injury Patients?. Frontiers in Neurology 8.
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Yuan Peng, Haifeng Zhu, Haodong Chen, Zijin Zhu, Huahai Zhou, Shuguang Zhang, Lili Gao, Lei Shi, Xiaoliang Li & Zhengxiang Luo. (2017) Dexmedetomidine attenuates acute paroxysmal sympathetic hyperactivity. Oncotarget 8:40, pages 69012-69019.
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