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Current Eye Research Volume 30, 2005 - Issue 4
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Research Article

Pharmacokinetic and Pharmacodynamic Analysis of Systemic Effect of Topically Applied Timolol Maleate Ophthalmic Gelling Vehicle (Rysmon® TG)

Yoshiyuki Ohno Department of Pharmacy, University of Tokyo Hospital, Faculty of Medicine, University of Tokyo, Tokyo, Japan
,
Risa Takayanagi Department of Pharmacy, University of Tokyo Hospital, Faculty of Medicine, University of Tokyo, Tokyo, Japan
,
Tatuji Iga Department of Pharmacy, University of Tokyo Hospital, Faculty of Medicine, University of Tokyo, Tokyo, Japan
,
Yasuhiko Yamada Department of Clinical Evaluation of Drug Efficacy, School of Pharmacy, Tokyo University of Pharmacy and Life Science, Tokyo, Japan
,
Miyuki Nagahara Department of Ophthalmology, University of Tokyo Hospital, Faculty of Medicine, University of Tokyo, Tokyo, Japan
&
Makoto Araie Department of Ophthalmology, University of Tokyo Hospital, Faculty of Medicine, University of Tokyo, Tokyo, Japan
Pages 319-328 | Received 04 Jul 2004, Accepted 03 Oct 2004, Published online: 02 Jul 2009

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T. Nieminen, T. Lehtimäki, J. Mäenpää, A. Ropo, H. Uusitalo & M. Kähönen. (2007) Ophthalmic timolol: Plasma concentration and systemic cardiopulmonary effects. Scandinavian Journal of Clinical and Laboratory Investigation 67:2, pages 237-245.
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Articles from other publishers (9)

Daniel J. Yoon, Ramanjot Kaur, Anthony Gallegos, Kaitlyn West, Hsinya Yang, Saul Schaefer, Catherine Tchanque-Fossuo, Sara E. Dahle & R. Rivkah Isseroff. (2020) Repurposing Ophthalmologic Timolol for Dermatologic Use: Caveats and Historical Review of Adverse Events. American Journal of Clinical Dermatology 22:1, pages 89-99.
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Miguel Moreno Raja, Pei Qi Lim, Yee Shan Wong, Gordon M. Xiong, Yiming Zhang, Subbu Venkatraman & Yingying Huang. 2019. Nanocarriers for Drug Delivery. Nanocarriers for Drug Delivery 557 653 .
Daisuke Iohara, Masanori Okubo, Makoto Anraku, Shunji Uramatsu, Toshio Shimamoto, Kaneto Uekama & Fumitoshi Hirayama. (2017) Hydrophobically Modified Polymer/α-Cyclodextrin Thermoresponsive Hydrogels for Use in Ocular Drug Delivery. Molecular Pharmaceutics 14:8, pages 2740-2748.
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Jaleh Barar, Ayuob Aghanejad, Marziyeh Fathi & Yadollah Omidi. (2016) Advanced drug delivery and targeting technologies for the ocular diseases. BioImpacts 6:1, pages 49-67.
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Nicole L. Pratt, Emmae N. Ramsay, Lisa M. Kalisch Ellett, Tuan A. Nguyen & Elizabeth E. Roughead. (2015) Association between Ophthalmic Timolol and Hospitalisation for Bradycardia. Journal of Ophthalmology 2015, pages 1-6.
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Christopher B. Chambers, William R. Katowitz, James A. Katowitz & Gil Binenbaum. (2012) A Controlled Study of Topical 0.25% Timolol Maleate Gel for the Treatment of Cutaneous Infantile Capillary Hemangiomas. Ophthalmic Plastic & Reconstructive Surgery 28:2, pages 103-106.
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KK Lau, HW Ng & ML Tse. (2017) Timolol Eye Drops Induced Bradycardia. Hong Kong Journal of Emergency Medicine 17:1, pages 71-74.
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Ken-ichi Shimokawa, Katsuhiko Saegusa & Fumiyoshi Ishii. (2009) Rheological properties of reversible thermo-setting in situ gelling solutions with the methylcellulose–polyethylene glycol–citric acid ternary system (2): Effects of various water-soluble polymers and salts on the gelling temperature. Colloids and Surfaces B: Biointerfaces 74:1, pages 56-58.
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Deepta Ghate & Henry F. Edelhauser. (2008) Barriers to Glaucoma Drug Delivery. Journal of Glaucoma 17:2, pages 147-156.
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