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Current Eye Research Volume 30, 2005 - Issue 8

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Original Article

Systemic and Periocular Deliveries of Plasminogen Kringle 5 Reduce Vascular Leakage in Rat Models of Oxygen-Induced Retinopathy and Diabetes

Sarah X. Zhang Department of Medicine, Department of Cell Biology, The University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA

Jing Sima Department of Medicine, Department of Cell Biology, The University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA

Joshua J. Wang Department of Medicine, Department of Cell Biology, The University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA

Chunkui Shao Department of Medicine, Department of Cell Biology, The University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA

James Fant Department of Medicine, Department of Cell Biology, The University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA

Jian-xing Ma Department of Medicine, Department of Cell Biology, The University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA

Pages 681-689 | Received 13 Apr 2004, Accepted 10 Nov 2004, Published online: 02 Jul 2009

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https://doi.org/10.1080/02713680590934102

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Burak Turgut. 2024. Retinal and Choroidal Vascular Diseases of the Eye. Retinal and Choroidal Vascular Diseases of the Eye 13 32 .

Biplab Sarkar, Zain Siddiqui, Ka Kyung Kim, Peter K. Nguyen, Xavier Reyes, Trevor J. McGill & Vivek A. Kumar. (2020) Implantable anti-angiogenic scaffolds for treatment of neovascular ocular pathologies. Drug Delivery and Translational Research 10:5, pages 1191-1202.
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Peter K. Nguyen, Biplab Sarkar, Zain Siddiqui, Michael McGowan, Patricia Iglesias-Montoro, Sruti Rachapudi, Soojin Kim, William Gao, Eun Jung Lee & Vivek A. Kumar. (2018) Self-Assembly of an Antiangiogenic Nanofibrous Peptide Hydrogel. ACS Applied Bio Materials 1:3, pages 865-870.
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Selwyn M. Prea, Elsa C. Chan, Gregory J. Dusting, Algis J. Vingrys, Bang V. Bui & Guei-Sheung Liu. (2015) Gene Therapy with Endogenous Inhibitors of Angiogenesis for Neovascular Age-Related Macular Degeneration: Beyond Anti-VEGF Therapy. Journal of Ophthalmology 2015, pages 1-12.
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Giovanni Casini, Massimo Dal Monte, Irene Fornaciari, Luca Filippi & Paola Bagnoli. (2014) The β-adrenergic system as a possible new target for pharmacologic treatment of neovascular retinal diseases. Progress in Retinal and Eye Research 42, pages 103-129.
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Yimin Zhong, Jingming Li, Yanming Chen, Joshua J. Wang, Rajiv Ratan & Sarah X. Zhang. (2012) Activation of Endoplasmic Reticulum Stress by Hyperglycemia Is Essential for Müller Cell–Derived Inflammatory Cytokine Production in Diabetes. Diabetes 61:2, pages 492-504.
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Jingming Li, Joshua J. Wang & Sarah X. Zhang. (2011) Preconditioning with Endoplasmic Reticulum Stress Mitigates Retinal Endothelial Inflammation via Activation of X-box Binding Protein 1. Journal of Biological Chemistry 286:6, pages 4912-4921.
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Hans E. Grossniklaus, Shin J. Kang & Lennart Berglin. (2010) Animal models of choroidal and retinal neovascularization. Progress in Retinal and Eye Research 29:6, pages 500-519.
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R A Mahdy, W M Nada, K M Hadhoud & S A El-Tarhony. (2010) The role of vascular endothelial growth factor in the progression of diabetic vascular complications. Eye 24:10, pages 1576-1584.
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Kyoungmin ParkYing ChenYang HuAaron S. MayoUday B. KompellaRichard LongerasJian-xing Ma. (2009) Nanoparticle-Mediated Expression of an Angiogenic Inhibitor Ameliorates Ischemia-Induced Retinal Neovascularization and Diabetes-Induced Retinal Vascular Leakage. Diabetes 58:8, pages 1902-1913.
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Jingming Li, Joshua J. Wang, Qiang Yu, Min Wang & Sarah X. Zhang. (2009) Endoplasmic reticulum stress is implicated in retinal inflammation and diabetic retinopathy. FEBS Letters 583:9, pages 1521-1527.
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Katja Vehanen, Margit Hornof, Arto Urtti & Hannu Uusitalo. (2008) Peribulbar poloxamer for ocular drug delivery. Acta Ophthalmologica 86:1, pages 91-96.
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David A. Antonetti, Heather D. VanGuilder & Cheng Mao-Lin. 2008. Diabetic Retinopathy. Diabetic Retinopathy 333 352 .

Sarah X. Zhang & Jian-xing Ma. (2007) Ocular neovascularization: Implication of endogenous angiogenic inhibitors and potential therapy. Progress in Retinal and Eye Research 26:1, pages 1-37.
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. (2006) Current World Literature. Current Opinion in Ophthalmology 17:6, pages 574-583.
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Systemic and Periocular Deliveries of Plasminogen Kringle 5 Reduce Vascular Leakage in Rat Models of Oxygen-Induced Retinopathy and Diabetes

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Systemic and Periocular Deliveries of Plasminogen Kringle 5 Reduce Vascular Leakage in Rat Models of Oxygen-Induced Retinopathy and Diabetes

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