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Original Article

Oxidative Stress and Antioxidant Activity in Orbital Fibroadipose Tissue in Graves' Ophthalmopathy

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Pages 421-427 | Received 28 Nov 2007, Accepted 02 Apr 2008, Published online: 02 Jul 2009

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Read on this site (2)

Mohsen Bahmani Kashkouli, Mohamadreza Aghamirsalim, Naser Karimi & Sahab Shahrzad. (2015) Autoimmune hyperthyroidism and thyroid eye disease: what is the role of pro-oxidants and antioxidants?. Expert Review of Ophthalmology 10:2, pages 135-143.
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Apjit Kaur, Sukant Pandey, Sandeep Kumar, Abbas A. Mehdi & Arvind Mishra. (2010) Oxidative Stress Profile in Graves’ Ophthalmopathy in Indian Patients. Orbit 29:2, pages 97-101.
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Francesco Buonfiglio, Katharina A. Ponto, Norbert Pfeiffer, George J. Kahaly & Adrian Gericke. (2024) Redox mechanisms in autoimmune thyroid eye disease. Autoimmunity Reviews 23:5, pages 103534.
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Tracy Aoun, Diana Danielova Gueorguieva & Kevin Y. Wu. (2024) Orbital Inflammation in Thyroid Eye Disease: Stress Responses and Their Implications. Stresses 4:1, pages 54-78.
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Sainan Chen, Jiale Diao, Zifan Yue & Ruili Wei. (2023) Identification and validation of ferroptosis-related genes and immune cell infiltration in thyroid associated ophthalmopathy. Frontiers in Genetics 14.
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Diana Bajkowska, Małgorzata Szelachowska, Angelika Buczyńska, Adam Jacek Krętowski & Katarzyna Siewko. (2022) Tears as a Source of Biomarkers in the Diagnosis of Graves’ Orbitopathy. Biomolecules 12:11, pages 1620.
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Chao Ma, Haoyu Li, Wei Liu, Shuwen Lu, Xian Li, Jinyuan Chen, Kaijun Li & Wenzhan Wang. (2022) Therapeutic Effect of Gypenosides on Antioxidant Stress Injury in Orbital Fibroblasts of Graves’ Orbitopathy. Journal of Immunology Research 2022, pages 1-20.
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Stephanie Hiu Ling Poon, Janice Jing-Chee Cheung, Kendrick Co Shih & Yau Kei Chan. (2022) A systematic review of multimodal clinical biomarkers in the management of thyroid eye disease. Reviews in Endocrine and Metabolic Disorders 23:3, pages 541-567.
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Shadi Akbarian, Samira Chaibakhsh, MohsenBahmani Kashkouli, Nasser Karimi, Parya Abdolalizadeh & Hossein Ghahvehchian. (2022) A systematic review on the role of antioxidants in thyroid eye disease. Journal of Current Ophthalmology 34:1, pages 16.
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Tzu-Yu Hou, Shi-Bei Wu, Hui-Chuan Kau & Chieh-Chih Tsai. (2021) The Role of Oxidative Stress and Therapeutic Potential of Antioxidants in Graves’ Ophthalmopathy. Biomedicines 9:12, pages 1871.
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Magdalena Londzin-Olesik, Beata Kos-Kudla, Jacek Karpe, Aleksandra Nowak & Mariusz Nowak. (2020) The Effect of Immunosuppression on Selected Antioxidant Parameters in Patients with Graves’ Disease with Active Thyroid-Associated Orbitopathy. Experimental and Clinical Endocrinology & Diabetes 129:10, pages 762-769.
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Bo-Yeon Kim, Sun-Young JangDug-Hyun Choi, Chan-Hee Jung, Ji-Oh Mok & Chul-Hee Kim. (2021) Anti-inflammatory and Antioxidant Effects of Selenium on Orbital Fibroblasts of Patients With Graves Ophthalmopathy. Ophthalmic Plastic & Reconstructive Surgery 37:5, pages 476-481.
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Sahil Agrawal, Rajendra Prakash Maurya, Ananya P R, Syeed Mehbub UL Kadir, Virendra Pratap Singh, Deepsekhar Das, Saloni Gupta, Vibha Singh & Meghna Roy. (2021) Recent advances in thyroid eye disease: An overview. IP International Journal of Ocular Oncology and Oculoplasty 7:2, pages 117-130.
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Giulia Lanzolla, Michele Marinò & Claudio Marcocci. (2021) Selenium in the Treatment of Graves’ Hyperthyroidism and Eye Disease. Frontiers in Endocrinology 11.
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Magdalena Londzin-Olesik, Beata Kos-Kudła, Aleksandra Nowak & Mariusz Nowak. (2021) Rola stresu oksydacyjnego w patogenezie orbitopatii Gravesa. Postępy Higieny i Medycyny Doświadczalnej 75:1, pages 448-455.
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Giulia Lanzolla, Claudio Marcocci & Michele Marinò. (2020) Antioxidant Therapy in Graves’ Orbitopathy. Frontiers in Endocrinology 11.
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Cetin Akpolat, Muhammed M. Kurt, Merve Yılmaz, Fikriye Ordulu & Ferhat Evliyaoglu. (2020) Analysis of Foveal and Parafoveal Microvascular Density and Retinal Vessel Caliber Alteration in Inactive Graves’ Ophthalmopathy. Journal of Ophthalmology 2020, pages 1-8.
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Nilay Yuksel, Derya Yaman, Ozge Tugce Pasaoglu & Hatice Pasaoglu. (2020) The Effect of Smoking on Mitochondrial Biogenesis in Patients With Graves Ophthalmopathy. Ophthalmic Plastic & Reconstructive Surgery 36:2, pages 172-177.
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JaeSang Ko, Ji-Young Kim, Jae-woo Kim & Jin Sook Yoon. (2020) Anti-oxidative and anti-adipogenic effects of caffeine in an <i>in vitro</i> model of Graves’ orbitopathy. Endocrine Journal 67:4, pages 439-447.
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Giulia Lanzolla, Claudio Marcocci & Michele Marinò. (2020) Oxidative Stress in Graves Disease and Graves Orbitopathy. European Thyroid Journal 9:Suppl. 1, pages 40-50.
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Michele Marinò, Giulia Lanzolla, Giovanna Rotondo Dottore & Claudio Marcocci. 2020. Pathology. Pathology 335 344 .
Olga Łach, Jakub Wojnarowicz & Mariusz Nowak. (2019) The role of oxidation-reduction mechanisms in pathogenesis of thyroid orbitopathy. Annales Academiae Medicae Silesiensis 73, pages 150-153.
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Won Choi, Ying Li, Yong Sok Ji & Kyung Chul Yoon. (2018) Oxidative stress markers in tears of patients with Graves’ orbitopathy and their correlation with clinical activity score. BMC Ophthalmology 18:1.
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Michele Marinò, Francesca Menconi, Giovanna Rotondo Dottore, Marenza Leo & Claudio Marcocci. (2018) Selenium in Graves Hyperthyroidism and Orbitopathy. Ophthalmic Plastic & Reconstructive Surgery 34:4S, pages S105-S110.
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Jwu Jin Khong, Alan A McNab, Peter R Ebeling, Jamie E Craig & Dinesh Selva. (2016) Pathogenesis of thyroid eye disease: review and update on molecular mechanisms. British Journal of Ophthalmology 100:1, pages 142-150.
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Guy J. Ben Simon, Gabriel Katz, Ofira Zloto, Hana Leiba, Beatrix Hadas & Ruth Huna-Baron. (2015) Age differences in clinical manifestation and prognosis of thyroid eye disease. Graefe's Archive for Clinical and Experimental Ophthalmology 253:12, pages 2301-2308.
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Chieh-Chih Tsai, Shi-Bei Wu, Pei-Chen Chang & Yau-Huei Wei. (2015) Alteration of Connective Tissue Growth Factor (CTGF) Expression in Orbital Fibroblasts from Patients with Graves’ Ophthalmopathy. PLOS ONE 10:11, pages e0143514.
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Lancelot MariqueMaximin SenouJulie CrapsAurélie DelaigleElliott Van RegemorterAlexis WérionVictoria Van RegemorterMichel MouradCatherine Nyssen-BehetsBenoit LengeléLelio BaldeschiAntonella BoschiSonia BrichardChantal DaumerieMarie-Christine Many. (2015) Oxidative Stress and Upregulation of Antioxidant Proteins, Including Adiponectin, in Extraocular Muscular Cells, Orbital Adipocytes, and Thyrocytes in Graves' Disease Associated with Orbitopathy. Thyroid 25:9, pages 1033-1042.
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Claudio Marcocci & Francesca Menconi. 2015. Thyroid Eye Disease. Thyroid Eye Disease 53 61 .
He Li, Caroline Fitchett, Katarzyna Kozdon, Hari Jayaram, Geoffrey E. Rose, Maryse Bailly & Daniel G. Ezra. (2014) Independent Adipogenic and Contractile Properties of Fibroblasts in Graves’ Orbitopathy: An In Vitro Model for the Evaluation of Treatments. PLoS ONE 9:4, pages e95586.
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Claudio Marcocci, Maria Antonietta Altea & Francesca Menconi. 2014. Handbook of Nutrition, Diet and the Eye. Handbook of Nutrition, Diet and the Eye 361 369 .
Masahiro Sugawara. 2014. Systems Biology of Free Radicals and Antioxidants. Systems Biology of Free Radicals and Antioxidants 3521 3538 .
Li-hong JIANG & Rui-li WEI. (2013) Analysis of Graves’ ophthalmopathy patients’ tear protein spectrum. Chinese Medical Journal 126:23, pages 4493-4498.
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Kai-Chun Cheng, Han-Hsiang Huang, Chun-Tzu Hung, Cheng-Chi Chen, Wen-Chuan Wu, Jau-Ling Suen, Kuo-Jen Chen, Yu-Jen Wu & Cheng-Hsien Chang. (2013) Proteomic analysis of the differences in orbital protein expression in thyroid orbitopathy. Graefe's Archive for Clinical and Experimental Ophthalmology 251:12, pages 2777-2787.
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Jin Sook Yoon, Hyun Jung Lee, Min Kyung Chae, Sang Yeul Lee & Eun Jig Lee. (2013) Cigarette smoke extract-induced adipogenesis in Graves' orbital fibroblasts is inhibited by quercetin via reduction in oxidative stress. Journal of Endocrinology 216:2, pages 145-156.
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I. Genol Saavedra, N. Toledano Fernández & A. Nogueira Goriba. (2012) Oxidative stress and Graves’ orbitopathy. Archivos de la Sociedad Española de Oftalmología (English Edition) 87:8, pages 235-236.
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I. Genol Saavedra, N. Toledano Fernández & A. Nogueira Goriba. (2012) Estrés oxidativo y orbitopatía de Graves. Archivos de la Sociedad Española de Oftalmología 87:8, pages 235-236.
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Suk Jin KimHaeng Ku KangSung Mo Kang. (2012) The Antifibrotic Effects of α-Tocotrienols in Primary Cultured Orbital Fibroblasts from Thyroid-Associated Ophthalmopathy Patients. Journal of the Korean Ophthalmological Society 53:2, pages 323.
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Miloš Žarković. (2012) The Role of Oxidative Stress on the Pathogenesis of Graves' Disease. Journal of Thyroid Research 2012, pages 1-5.
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C-C Tsai, S-B Wu, C-Y Cheng, S-C Kao, H-C Kau, S-H Chiou, W-M Hsu & Y-H Wei. (2010) Increased oxidative DNA damage, lipid peroxidation, and reactive oxygen species in cultured orbital fibroblasts from patients with Graves’ ophthalmopathy: evidence that oxidative stress has a role in this disorder. Eye 24:9, pages 1520-1525.
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